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The map label for this gene is yhxC [H]

Identifier: 119868875

GI number: 119868875

Start: 2964298

End: 2964984

Strand: Direct

Name: yhxC [H]

Synonym: Mkms_2843

Alternate gene names: 119868875

Gene position: 2964298-2964984 (Clockwise)

Preceding gene: 119868871

Following gene: 119868876

Centisome position: 51.67

GC content: 70.16

Gene sequence:

>687_bases
ATGGAGGTGCTGGTCACCGGCGGCGATACCGATCTGGGCCGGACGATCGCGGAGGGTTTCCGCGACGACGGCCACCGGGT
GGTGATCGCCGGAGCGCGGCGTGAGGACCTGGAGATCAACGCCAAGGAACTCGACGTCGACTCGATCGTCTTCGACAACA
CCGACCCGGCCGGCGTCGAAGAGGCCCGCTCGTTGTTCCCGCACCACCTCGACACCCTCGTCAACGTGCCCGCGCCGCAG
TATCCCCCGGCGGATCCGCGCACGTTCAGCCTGGCCGACCACGCCCTCGCCTGGCGGCGCGCCCTGGACACCACCGTCCT
GTCGGCCGTGCTGACGGTCCAGATCGTCGGCGACCATCTGCGCTCGGGCGGTTCGATCGTCAACGTCATCCCGGAGAACG
TCGTCATCGCCCAGGCCCGCGAGGGCAGCGTCGACGCCGCGATCAAGGCGGCGCTGTCCGACTGGACCGCCGGGCAGGCC
ACCCATTTCGGCACCCGCGGGATCACCGTCAATGCCGTCGCGACCGGTAAGAGCGCCGGACCGTCCTACGACGGTCTGTC
GAGCACCCCGCCCGCGGTGGCCGCCGAGATCGCCCGGATGGCCCTATTCCTGTCGACGCCTGCGGCCCGCCACATCACCG
GCCAGACCATGCATGTGAGCCGGGGTGCGCTCGCGAACTTCGGCTAG

Upstream 100 bases:

>100_bases
TCTGCGCGTCGGATTACCCGAGATAGCTACCGTCCAGTAACATCGACGGCGATCGCGGCCCACGCGCGCGGCGATCAAGC
CACACGAGGAGGTCATGGCG

Downstream 100 bases:

>100_bases
ACCGATAGGGTTGACGGAGTGACGATCCGACTCGGACTCCAGATCCCGAACTTCAGCTACGGCACCGGTGTCGCCGAACT
CTTCCCGACAGTCATCGCGC

Product: short chain dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: ORFX [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MEVLVTGGDTDLGRTIAEGFRDDGHRVVIAGARREDLEINAKELDVDSIVFDNTDPAGVEEARSLFPHHLDTLVNVPAPQ
YPPADPRTFSLADHALAWRRALDTTVLSAVLTVQIVGDHLRSGGSIVNVIPENVVIAQAREGSVDAAIKAALSDWTAGQA
THFGTRGITVNAVATGKSAGPSYDGLSSTPPAVAAEIARMALFLSTPAARHITGQTMHVSRGALANFG

Sequences:

>Translated_228_residues
MEVLVTGGDTDLGRTIAEGFRDDGHRVVIAGARREDLEINAKELDVDSIVFDNTDPAGVEEARSLFPHHLDTLVNVPAPQ
YPPADPRTFSLADHALAWRRALDTTVLSAVLTVQIVGDHLRSGGSIVNVIPENVVIAQAREGSVDAAIKAALSDWTAGQA
THFGTRGITVNAVATGKSAGPSYDGLSSTPPAVAAEIARMALFLSTPAARHITGQTMHVSRGALANFG
>Mature_228_residues
MEVLVTGGDTDLGRTIAEGFRDDGHRVVIAGARREDLEINAKELDVDSIVFDNTDPAGVEEARSLFPHHLDTLVNVPAPQ
YPPADPRTFSLADHALAWRRALDTTVLSAVLTVQIVGDHLRSGGSIVNVIPENVVIAQAREGSVDAAIKAALSDWTAGQA
THFGTRGITVNAVATGKSAGPSYDGLSSTPPAVAAEIARMALFLSTPAARHITGQTMHVSRGALANFG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 23919; Mature: 23919

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVLVTGGDTDLGRTIAEGFRDDGHRVVIAGARREDLEINAKELDVDSIVFDNTDPAGVE
CEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHCCCCEEEECCCCCCCHH
EARSLFPHHLDTLVNVPAPQYPPADPRTFSLADHALAWRRALDTTVLSAVLTVQIVGDHL
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGGSIVNVIPENVVIAQAREGSVDAAIKAALSDWTAGQATHFGTRGITVNAVATGKSAG
HCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCC
PSYDGLSSTPPAVAAEIARMALFLSTPAARHITGQTMHVSRGALANFG
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MEVLVTGGDTDLGRTIAEGFRDDGHRVVIAGARREDLEINAKELDVDSIVFDNTDPAGVE
CEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHCCCCEEEECCCCCCCHH
EARSLFPHHLDTLVNVPAPQYPPADPRTFSLADHALAWRRALDTTVLSAVLTVQIVGDHL
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGGSIVNVIPENVVIAQAREGSVDAAIKAALSDWTAGQATHFGTRGITVNAVATGKSAG
HCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCC
PSYDGLSSTPPAVAAEIARMALFLSTPAARHITGQTMHVSRGALANFG
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8196543 [H]