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The map label for this gene is ucpA [C]

Identifier: 119868814

GI number: 119868814

Start: 2900849

End: 2901697

Strand: Direct

Name: ucpA [C]

Synonym: Mkms_2782

Alternate gene names: 119868814

Gene position: 2900849-2901697 (Clockwise)

Preceding gene: 119868813

Following gene: 119868815

Centisome position: 50.56

GC content: 70.2

Gene sequence:

>849_bases
ATGACACCGCCGACGCAGACGCCCGGGACGACGAAGTCGATCTTCATCACGGGTGCGGGTAGCGGTATGGGACGCGCAGG
CGCGCAGCTGTTCCACGACCGCGGCTGGCGGGTCGCCGCCGTCGACCGCAACGAGGCCGGCCTGGCCGAGCTGACCGCCG
AACGCGGTGGCGACCGACTGTGGACCCGACAGGTCGACGTGACCGACAAGGCGCAGCTCGAGGCCGCGCTCGCCGACTTC
TGCGGTGACGGCGGCCTGGACATGATGTGGAACAACGCCGGGATCGGCGAATCCGGCTGGTTCGAGGACGTGCCGTACGA
AGCGGCCATGCGGGTGGTCGACGTCAACTTCAAGGCGGTGCTGACCGGGGCGTACGTGGCGCTGCCCTACCTCAAGCGGG
CGCCGGACAGCCTGATGTTCTCGACGTCGTCGTCGTCGGCGACCTACGGGATGCCGCAGATCGCGGTGTACTCGGCGACC
AAACACGGCGTCAAAGGCCTCACCGAGGCGCTCAGCGTGGAGTGGCAGCGGCACGGGGTGCGTGTCGCCGACGTGCTGCC
CGGACTGATCGACACGGCGATCCTGCGCGAGACACCCAACCGCTCCGGGCGTGCGCCGTCGGACGGTCCCGGTGCGGACG
TGACCGCTTCCGCGCCCAGGCGGGGTCCGTTCCGGTTGATGCCGGCCGTCAGTGTCGCCGAGGCGGCGTGGGCGGCCTAC
CGGCATCCGACCCGGCTGCACTGGTATGTGCCGAACAGCATCCGGTGGCTCGACCGGCTCAAGGCCGTCAGCCCGGAGTT
GGTCCGCGGCCAGATCCGTAAGGCGCTACCGCGGCTCATCGAGCGCTGA

Upstream 100 bases:

>100_bases
CGATGCGGTCGCGGCGTCCCGCGGCCTCGATGAGCTCTACCGGCACGCGCTGTCGTTCGCGACCCGGTCCTACTGCGGGT
GAACCTGTCAGGATGACCCG

Downstream 100 bases:

>100_bases
GGTTCAGTTCTCACGCGGCAGGAGTTCGGCGCGGCGCAGCGCGGCAGGCGCTGGTCCGCCGAGCCAGATGTCGAGCGGTC
GGTCGGACCTTCACACCTGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTPPTQTPGTTKSIFITGAGSGMGRAGAQLFHDRGWRVAAVDRNEAGLAELTAERGGDRLWTRQVDVTDKAQLEAALADF
CGDGGLDMMWNNAGIGESGWFEDVPYEAAMRVVDVNFKAVLTGAYVALPYLKRAPDSLMFSTSSSSATYGMPQIAVYSAT
KHGVKGLTEALSVEWQRHGVRVADVLPGLIDTAILRETPNRSGRAPSDGPGADVTASAPRRGPFRLMPAVSVAEAAWAAY
RHPTRLHWYVPNSIRWLDRLKAVSPELVRGQIRKALPRLIER

Sequences:

>Translated_282_residues
MTPPTQTPGTTKSIFITGAGSGMGRAGAQLFHDRGWRVAAVDRNEAGLAELTAERGGDRLWTRQVDVTDKAQLEAALADF
CGDGGLDMMWNNAGIGESGWFEDVPYEAAMRVVDVNFKAVLTGAYVALPYLKRAPDSLMFSTSSSSATYGMPQIAVYSAT
KHGVKGLTEALSVEWQRHGVRVADVLPGLIDTAILRETPNRSGRAPSDGPGADVTASAPRRGPFRLMPAVSVAEAAWAAY
RHPTRLHWYVPNSIRWLDRLKAVSPELVRGQIRKALPRLIER
>Mature_281_residues
TPPTQTPGTTKSIFITGAGSGMGRAGAQLFHDRGWRVAAVDRNEAGLAELTAERGGDRLWTRQVDVTDKAQLEAALADFC
GDGGLDMMWNNAGIGESGWFEDVPYEAAMRVVDVNFKAVLTGAYVALPYLKRAPDSLMFSTSSSSATYGMPQIAVYSATK
HGVKGLTEALSVEWQRHGVRVADVLPGLIDTAILRETPNRSGRAPSDGPGADVTASAPRRGPFRLMPAVSVAEAAWAAYR
HPTRLHWYVPNSIRWLDRLKAVSPELVRGQIRKALPRLIER

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=32.1428571428571, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI7705925, Length=184, Percent_Identity=31.5217391304348, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI20149619, Length=230, Percent_Identity=25.2173913043478, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=32.4742268041237, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7657478, Length=187, Percent_Identity=28.8770053475936, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI19743808, Length=198, Percent_Identity=31.3131313131313, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=30.8900523560209, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40548397, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI214010158, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI214010156, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI22758144, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI66933014, Length=168, Percent_Identity=29.7619047619048, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=168, Percent_Identity=30.952380952381, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680136, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI44680133, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI17738292, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=187, Percent_Identity=29.9465240641711, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=27.4725274725275, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790717, Length=194, Percent_Identity=27.319587628866, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=193, Percent_Identity=27.979274611399, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=28.4974093264249, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=194, Percent_Identity=27.8350515463918, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=200, Percent_Identity=28, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=195, Percent_Identity=27.6923076923077, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=193, Percent_Identity=32.6424870466321, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=31.3829787234043, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356301, Length=184, Percent_Identity=26.6304347826087, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=29.4736842105263, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI23397609, Length=190, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=31.413612565445, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI18859837, Length=184, Percent_Identity=28.804347826087, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30571; Mature: 30440

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPTQTPGTTKSIFITGAGSGMGRAGAQLFHDRGWRVAAVDRNEAGLAELTAERGGDRL
CCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCEE
WTRQVDVTDKAQLEAALADFCGDGGLDMMWNNAGIGESGWFEDVPYEAAMRVVDVNFKAV
EEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHEEEEECCHHHH
LTGAYVALPYLKRAPDSLMFSTSSSSATYGMPQIAVYSATKHGVKGLTEALSVEWQRHGV
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCE
RVADVLPGLIDTAILRETPNRSGRAPSDGPGADVTASAPRRGPFRLMPAVSVAEAAWAAY
EHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHH
RHPTRLHWYVPNSIRWLDRLKAVSPELVRGQIRKALPRLIER
CCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPPTQTPGTTKSIFITGAGSGMGRAGAQLFHDRGWRVAAVDRNEAGLAELTAERGGDRL
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCEE
WTRQVDVTDKAQLEAALADFCGDGGLDMMWNNAGIGESGWFEDVPYEAAMRVVDVNFKAV
EEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHEEEEECCHHHH
LTGAYVALPYLKRAPDSLMFSTSSSSATYGMPQIAVYSATKHGVKGLTEALSVEWQRHGV
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCE
RVADVLPGLIDTAILRETPNRSGRAPSDGPGADVTASAPRRGPFRLMPAVSVAEAAWAAY
EHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHH
RHPTRLHWYVPNSIRWLDRLKAVSPELVRGQIRKALPRLIER
CCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]