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The map label for this gene is fur [H]

Identifier: 119868759

GI number: 119868759

Start: 2851408

End: 2851881

Strand: Direct

Name: fur [H]

Synonym: Mkms_2726

Alternate gene names: 119868759

Gene position: 2851408-2851881 (Clockwise)

Preceding gene: 119868754

Following gene: 119868760

Centisome position: 49.7

GC content: 68.78

Gene sequence:

>474_bases
ATGGCTGTCGTGTCGTCGTCGTCCGAGTACGTGGACCAGTTGCGGGGCGCGGATCTGCGCGTCACCCGTCCCCGGGTCGC
CGTGCTGGAAGCGGTCCACGCCCACCCCCACGCAGACACCGAGACCATCTTCGCCACCGTCCGGTCCAGTCTGCCGGACG
TATCGCGGCAGGCGGTCTACGACGTGCTGCACGCCCTGACCGGCGCCCGTTTGATCCGGCGGATGCAACCGTCCGGTTCG
GTCGCCCGGTACGAGACCCGCGTCGGCGACAACCACCACCACGTGGTGTGCCGCTCGTGCGGGACGATCGCCGACGTGGA
CTGCGCGGTGGGCGAAGCCCCGTGCCTGATGCCGTCCGAACACGACGCTCTCGACGGCTTCGTCCTCGACGAGGCCGAAG
TCATCTACTGGGGCGTCTGCCCCGACTGCGCCGCCGAGAGTTCCACCGCAGATAGTTCCCGATCACATCCGTGA

Upstream 100 bases:

>100_bases
CGGGCTGAAGTCACGGATATGCCTGGCGCGCAGGCCGATTGGCGTTTCGGCGCAAAACGCCCGCGATGAACTCTTGACTT
ATTCCAAAAAAGCGGGTGAT

Downstream 100 bases:

>100_bases
TCGCAGCCCATCACCACCTTGATGTATGGAATACGAAGGGAAACACCGTGTCATCCGATACCTCCGATACCCGCCCCCCG
CACTCTGACTCCGGAACCCA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MAVVSSSSEYVDQLRGADLRVTRPRVAVLEAVHAHPHADTETIFATVRSSLPDVSRQAVYDVLHALTGARLIRRMQPSGS
VARYETRVGDNHHHVVCRSCGTIADVDCAVGEAPCLMPSEHDALDGFVLDEAEVIYWGVCPDCAAESSTADSSRSHP

Sequences:

>Translated_157_residues
MAVVSSSSEYVDQLRGADLRVTRPRVAVLEAVHAHPHADTETIFATVRSSLPDVSRQAVYDVLHALTGARLIRRMQPSGS
VARYETRVGDNHHHVVCRSCGTIADVDCAVGEAPCLMPSEHDALDGFVLDEAEVIYWGVCPDCAAESSTADSSRSHP
>Mature_156_residues
AVVSSSSEYVDQLRGADLRVTRPRVAVLEAVHAHPHADTETIFATVRSSLPDVSRQAVYDVLHALTGARLIRRMQPSGSV
ARYETRVGDNHHHVVCRSCGTIADVDCAVGEAPCLMPSEHDALDGFVLDEAEVIYWGVCPDCAAESSTADSSRSHP

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16938; Mature: 16807

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVVSSSSEYVDQLRGADLRVTRPRVAVLEAVHAHPHADTETIFATVRSSLPDVSRQAVY
CCEECCCHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
DVLHALTGARLIRRMQPSGSVARYETRVGDNHHHVVCRSCGTIADVDCAVGEAPCLMPSE
HHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCCEEEECCCCCCCCCHHCCCCCCCCCCCC
HDALDGFVLDEAEVIYWGVCPDCAAESSTADSSRSHP
CCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVVSSSSEYVDQLRGADLRVTRPRVAVLEAVHAHPHADTETIFATVRSSLPDVSRQAVY
CEECCCHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
DVLHALTGARLIRRMQPSGSVARYETRVGDNHHHVVCRSCGTIADVDCAVGEAPCLMPSE
HHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCCEEEECCCCCCCCCHHCCCCCCCCCCCC
HDALDGFVLDEAEVIYWGVCPDCAAESSTADSSRSHP
CCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]