BacMap

Definition	Mycobacterium sp. KMS chromosome, complete genome.
Accession	NC_008705
Length	5,737,227

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The map label for this gene is fabG [H]

Identifier: 119868735

GI number: 119868735

Start: 2826128

End: 2826889

Strand: Direct

Name: fabG [H]

Synonym: Mkms_2702

Alternate gene names: 119868735

Gene position: 2826128-2826889 (Clockwise)

Preceding gene: 119868734

Following gene: 119868737

Centisome position: 49.26

GC content: 71.26

Gene sequence:

>762_bases
GTGGACCTGGGCCTGACCGGCAAACGATTCGCCGTCACCGGCGGCACCCGCGGCATCGGCCGAGCGGTCGTCGAGGGTCT
GCTCGCCGAAGGGGCCGTGGTCGCGTTCTGCGCACGCACCCCCGAGGCGGTCACCGACGCGCAGGCGGAGTTGACGGCCG
ACGGCGCCACCGCCGTCGGTGCGGCGGTGGACGTCGGTGACCCGACAGCGCTGACCGCCTGGGTGGGCGCCGCCGCGGAC
TCGCTGGGCGGCCTGGACGGGGTGGTGGCCAACGTCAGCGCGCTGGCGATTCCGGAGTCCGCGGAGAACTGGCGCGCGTC
CTTCGACGTCGATCTGATGGGCACCGTGGGTCTGGTCGACGCCGCCCTGCCACACCTGCTGGCCGCGGGTGGCGGGTCGA
TCGTGACGATCTCGAGTGTGTCCGGGCGGGAGATCGACTTCGCCGCCGGCCCGTACGGGACGATGAAGGCCGCGATCATC
CATTACACCCAGGGCCTGGCGTACCGACTCGCCGCTCAGGGGATACGCGCGAACACCGTCAGCCCGGGCAACACGTACTT
TCCCGGCGGGGTGTGGACCTCGATCGAGGAGCACAACCCGGAACTGTTCGCCACGGCGCTCGCACTGAACCCGACCGGCC
GCATGGCGACCCCGCAGGAGGTGGCCAACGCGGTGCTGTTCCTCAGCAGTTCCGCGGCCAGCTTCGTCACCGGTACGAAC
CTGCTCGTCGACGGAGCGCTGACGCGCGGCGTGCAACTCTGA

Upstream 100 bases:

>100_bases
AAGCGTCTTCTGCCCACCGTCGCGGTCTATGACGGGATCCACGCTGAACTCCGCTCCGCGGCAGCATCATTCGGAACGAT
CACCTACTGAGGGGACTGTC

Downstream 100 bases:

>100_bases
GGCCTCACCCCACCTCGAGTGGTACGGCCATCTCCCGGCCCCCGCCGCGGGCAGCCCCGATCCCGGCGACGACCACCGCG
GCGATGCCGAGGATGCCCGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MDLGLTGKRFAVTGGTRGIGRAVVEGLLAEGAVVAFCARTPEAVTDAQAELTADGATAVGAAVDVGDPTALTAWVGAAAD
SLGGLDGVVANVSALAIPESAENWRASFDVDLMGTVGLVDAALPHLLAAGGGSIVTISSVSGREIDFAAGPYGTMKAAII
HYTQGLAYRLAAQGIRANTVSPGNTYFPGGVWTSIEEHNPELFATALALNPTGRMATPQEVANAVLFLSSSAASFVTGTN
LLVDGALTRGVQL

Sequences:

>Translated_253_residues
MDLGLTGKRFAVTGGTRGIGRAVVEGLLAEGAVVAFCARTPEAVTDAQAELTADGATAVGAAVDVGDPTALTAWVGAAAD
SLGGLDGVVANVSALAIPESAENWRASFDVDLMGTVGLVDAALPHLLAAGGGSIVTISSVSGREIDFAAGPYGTMKAAII
HYTQGLAYRLAAQGIRANTVSPGNTYFPGGVWTSIEEHNPELFATALALNPTGRMATPQEVANAVLFLSSSAASFVTGTN
LLVDGALTRGVQL
>Mature_253_residues
MDLGLTGKRFAVTGGTRGIGRAVVEGLLAEGAVVAFCARTPEAVTDAQAELTADGATAVGAAVDVGDPTALTAWVGAAAD
SLGGLDGVVANVSALAIPESAENWRASFDVDLMGTVGLVDAALPHLLAAGGGSIVTISSVSGREIDFAAGPYGTMKAAII
HYTQGLAYRLAAQGIRANTVSPGNTYFPGGVWTSIEEHNPELFATALALNPTGRMATPQEVANAVLFLSSSAASFVTGTN
LLVDGALTRGVQL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=30, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=30.4347826086957, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=32.1739130434783, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=30, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=28.9795918367347, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=32.156862745098, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=28.125, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=29.6, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=173, Percent_Identity=32.3699421965318, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI10190704, Length=241, Percent_Identity=29.045643153527, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=30.9803921568627, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=31.3253012048193, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=30.6451612903226, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=30.5882352941176, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=28.90625, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=31.1740890688259, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=25.3012048192771, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=31.7460317460317, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=25.968992248062, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=30.952380952381, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193204405, Length=278, Percent_Identity=28.4172661870504, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=33.2089552238806, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=30.6772908366534, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=28.735632183908, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=29.8850574712644, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=256, Percent_Identity=27.734375, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.90625, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=29.6442687747036, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=26.8199233716475, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=26.7924528301887, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.1368821292776, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=274, Percent_Identity=27.007299270073, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=26.7924528301887, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=275, Percent_Identity=27.6363636363636, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=28.1632653061224, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=25.9398496240602, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=26.0536398467433, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=25.9398496240602, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=28.8973384030418, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=28.968253968254, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=26.615969581749, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=25.7462686567164, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=28.2868525896414, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=28.6259541984733, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=28.0769230769231, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193207185, Length=157, Percent_Identity=30.5732484076433, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=28.1746031746032, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=229, Percent_Identity=29.2576419213974, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=187, Percent_Identity=30.4812834224599, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=34.5238095238095, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=31.4741035856574, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=30.5220883534137, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=29.9595141700405, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=30.1960784313725, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=29.1497975708502, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644337, Length=118, Percent_Identity=40.6779661016949, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25384; Mature: 25384

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLTGKRFAVTGGTRGIGRAVVEGLLAEGAVVAFCARTPEAVTDAQAELTADGATAVG
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHCCCCEEECCCCHHHC
AAVDVGDPTALTAWVGAAADSLGGLDGVVANVSALAIPESAENWRASFDVDLMGTVGLVD
EEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCCCEECCEEECCHHHHHH
AALPHLLAAGGGSIVTISSVSGREIDFAAGPYGTMKAAIIHYTQGLAYRLAAQGIRANTV
HHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
SPGNTYFPGGVWTSIEEHNPELFATALALNPTGRMATPQEVANAVLFLSSSAASFVTGTN
CCCCCCCCCCEECCHHHCCCEEEEEEEEECCCCCCCCHHHHHHEEEEEECCCCHHEECCC
LLVDGALTRGVQL
EEEECHHHCCCCC
>Mature Secondary Structure
MDLGLTGKRFAVTGGTRGIGRAVVEGLLAEGAVVAFCARTPEAVTDAQAELTADGATAVG
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHCCCCEEECCCCHHHC
AAVDVGDPTALTAWVGAAADSLGGLDGVVANVSALAIPESAENWRASFDVDLMGTVGLVD
EEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCCCEECCEEECCHHHHHH
AALPHLLAAGGGSIVTISSVSGREIDFAAGPYGTMKAAIIHYTQGLAYRLAAQGIRANTV
HHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
SPGNTYFPGGVWTSIEEHNPELFATALALNPTGRMATPQEVANAVLFLSSSAASFVTGTN
CCCCCCCCCCEECCHHHCCCEEEEEEEEECCCCCCCCHHHHHHEEEEEECCCCHHEECCC
LLVDGALTRGVQL
EEEECHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]