| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
Click here to switch to the map view.
The map label for this gene is hpcC [H]
Identifier: 119868690
GI number: 119868690
Start: 2788424
End: 2789926
Strand: Reverse
Name: hpcC [H]
Synonym: Mkms_2657
Alternate gene names: 119868690
Gene position: 2789926-2788424 (Counterclockwise)
Preceding gene: 119868691
Following gene: 119868689
Centisome position: 48.63
GC content: 65.27
Gene sequence:
>1503_bases GTGACCGCGAACCGTCGGCCCGAGGGTGTACCGCAGCGCATCCAGCACTTCATCGGCGGGAAGTTGGTCGACAGCCTTGC CGACACGTGGTTCGACGTCATCGATCCGGTGACCAACCAGCCGTACGCGCAGGCCGCCGCAGGACAGGCCGACGATGTCG ACCGCGCGGTGGCCGCGGCCAAAGTCGCCTTCCGGACCGGGCCCTGGCCGAACATGCAGGCCCGGAGCCGTTCCCGGGTG CTGAACAGAATCGCGGACGCCATCGAGAGCCGCGATGCGCGGCTGGCCGAGTTGGAGTCGTTCGACAGCGGCCTGCCGAT CACGCAGGCGCTCGGCCAGGCCCGCCGCGCCGCCGAGAACTTCCGCTTCTTCGCCGACCTGGTGGTGGCGCAGGCCGACG ACGCCTACAAGGTGCCCGGCAGCCAGATCAACTACGTCAACCGCAAACCAAAAGGTGTCGCCGGCCTGATCACGCCATGG AACACCCCGTTCATGCTGGAGAGCTGGAAGTTGGCGCCGGCCTTGGCATCCGGATGCACCGTCGTATTAAAACCCGCCGA ATTCACTCCGCTGTCCGCTGGACTGTGGGCCGACATCTTCCGCGACGCGGGCGTTCCCGATGGGGTGTTCAACTTGGTCA ACGGCATTGGCGAAGAAGCCGGCGACGCGTTGGTCAAGCATCCCGACGTCAGAGTCATCTCCTTCACCGGTGAGTCGGCC ACCGGCGAGATCATCTTCCGCAACTGCGCCACCGGCCTCAAAGGCATGTCGATGGAACTCGGCGGCAAATCACCGGCGGT GGTGTTCGCCGATGCCGACCTCGACGCCGCCCTGGACTCCACGCTGTTCGGTGTCTTCTCACTCAACGGCGAGCGATGCA CGGCGGGCAGCCGCATCCTCGTCGAAGAGGAGATCTACGACGAATTCGTCGAACGGTTTGCCGCGCGGGCGGCCGGCATT GTGGTCGGGGATCCCCAGGATCCACGGACCGAGGTGGGTGCCCTGGTCCATCCTGAGCATTTCGCCAAAGTGATGTCCTA CATCGACGTCGGCAAGACAGAGGGACGGCTGCTGTGTGGGGGTGGGCGGCCGGCGCATCTGCCGCAGGGCAACTTCGTGG CGCCGACGGCCTTCGCCGATGTGGAGCCGAACGCGCGGATCTTTCAGGAGGAGATCTTCGGACCGGTGGTCGCGCTGTCG CGATTCCAGACCGAAGAGCAGGCGCTCGCGTTGGCTAATGGCGTGAAATACGGTCTGGCTGCTTACATCTGGACCAACGA CCTCAAACGTGCCCACCGGTTCGCGCAGAATGTCGACAGCGGCATGGTGTGGGTCAACTCCCACAACGTTCGCGATCTGC GCACCCCCTTCGGCGGAGTCAAGGCCTCGGGCCTTGGCCACGAAGGTGGCTACCGGTCCCTGGACTTCTACACCGACCAG CAGGCTGTGCACATCACCCTCGGCGACGTCCACACACCGAGATTCGGCATCACCGCCCGCTGA
Upstream 100 bases:
>100_bases CGCCGACGCCGGGCGCACTGGAGAGAATCGCCGTGTTGCGGCGTGCTGGCGAGAAGTTCCTCACGCCAGTAGGCGATTTC GCACTGGAAGGAGCTTTCGC
Downstream 100 bases:
>100_bases CCAGACTCCCTTCTGATGAAAGTGAGCCGACACATGGCCTCCGTTTCACCGCCCGACATCGTCCGCTGTGCGTACATGGA ATTGGTCGTCACCGACCTGG
Product: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+
Alternate protein names: CHMS dehydrogenase [H]
Number of amino acids: Translated: 500; Mature: 499
Protein sequence:
>500_residues MTANRRPEGVPQRIQHFIGGKLVDSLADTWFDVIDPVTNQPYAQAAAGQADDVDRAVAAAKVAFRTGPWPNMQARSRSRV LNRIADAIESRDARLAELESFDSGLPITQALGQARRAAENFRFFADLVVAQADDAYKVPGSQINYVNRKPKGVAGLITPW NTPFMLESWKLAPALASGCTVVLKPAEFTPLSAGLWADIFRDAGVPDGVFNLVNGIGEEAGDALVKHPDVRVISFTGESA TGEIIFRNCATGLKGMSMELGGKSPAVVFADADLDAALDSTLFGVFSLNGERCTAGSRILVEEEIYDEFVERFAARAAGI VVGDPQDPRTEVGALVHPEHFAKVMSYIDVGKTEGRLLCGGGRPAHLPQGNFVAPTAFADVEPNARIFQEEIFGPVVALS RFQTEEQALALANGVKYGLAAYIWTNDLKRAHRFAQNVDSGMVWVNSHNVRDLRTPFGGVKASGLGHEGGYRSLDFYTDQ QAVHITLGDVHTPRFGITAR
Sequences:
>Translated_500_residues MTANRRPEGVPQRIQHFIGGKLVDSLADTWFDVIDPVTNQPYAQAAAGQADDVDRAVAAAKVAFRTGPWPNMQARSRSRV LNRIADAIESRDARLAELESFDSGLPITQALGQARRAAENFRFFADLVVAQADDAYKVPGSQINYVNRKPKGVAGLITPW NTPFMLESWKLAPALASGCTVVLKPAEFTPLSAGLWADIFRDAGVPDGVFNLVNGIGEEAGDALVKHPDVRVISFTGESA TGEIIFRNCATGLKGMSMELGGKSPAVVFADADLDAALDSTLFGVFSLNGERCTAGSRILVEEEIYDEFVERFAARAAGI VVGDPQDPRTEVGALVHPEHFAKVMSYIDVGKTEGRLLCGGGRPAHLPQGNFVAPTAFADVEPNARIFQEEIFGPVVALS RFQTEEQALALANGVKYGLAAYIWTNDLKRAHRFAQNVDSGMVWVNSHNVRDLRTPFGGVKASGLGHEGGYRSLDFYTDQ QAVHITLGDVHTPRFGITAR >Mature_499_residues TANRRPEGVPQRIQHFIGGKLVDSLADTWFDVIDPVTNQPYAQAAAGQADDVDRAVAAAKVAFRTGPWPNMQARSRSRVL NRIADAIESRDARLAELESFDSGLPITQALGQARRAAENFRFFADLVVAQADDAYKVPGSQINYVNRKPKGVAGLITPWN TPFMLESWKLAPALASGCTVVLKPAEFTPLSAGLWADIFRDAGVPDGVFNLVNGIGEEAGDALVKHPDVRVISFTGESAT GEIIFRNCATGLKGMSMELGGKSPAVVFADADLDAALDSTLFGVFSLNGERCTAGSRILVEEEIYDEFVERFAARAAGIV VGDPQDPRTEVGALVHPEHFAKVMSYIDVGKTEGRLLCGGGRPAHLPQGNFVAPTAFADVEPNARIFQEEIFGPVVALSR FQTEEQALALANGVKYGLAAYIWTNDLKRAHRFAQNVDSGMVWVNSHNVRDLRTPFGGVKASGLGHEGGYRSLDFYTDQQ AVHITLGDVHTPRFGITAR
Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM) [H]
COG id: COG1012
COG function: function code C; NAD-dependent aldehyde dehydrogenases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldehyde dehydrogenase family [H]
Homologues:
Organism=Homo sapiens, GI25777732, Length=488, Percent_Identity=41.8032786885246, Blast_Score=373, Evalue=1e-103, Organism=Homo sapiens, GI12007648, Length=484, Percent_Identity=40.0826446280992, Blast_Score=366, Evalue=1e-101, Organism=Homo sapiens, GI25777730, Length=477, Percent_Identity=41.5094339622642, Blast_Score=361, Evalue=1e-100, Organism=Homo sapiens, GI153266822, Length=498, Percent_Identity=39.5582329317269, Blast_Score=352, Evalue=4e-97, Organism=Homo sapiens, GI25777724, Length=478, Percent_Identity=39.5397489539749, Blast_Score=336, Evalue=3e-92, Organism=Homo sapiens, GI21361176, Length=480, Percent_Identity=39.1666666666667, Blast_Score=333, Evalue=2e-91, Organism=Homo sapiens, GI238814322, Length=479, Percent_Identity=38.6221294363257, Blast_Score=326, Evalue=4e-89, Organism=Homo sapiens, GI115387104, Length=463, Percent_Identity=36.0691144708423, Blast_Score=322, Evalue=6e-88, Organism=Homo sapiens, GI21614513, Length=491, Percent_Identity=39.1038696537678, Blast_Score=320, Evalue=2e-87, Organism=Homo sapiens, GI25777728, Length=422, Percent_Identity=40.7582938388626, Blast_Score=311, Evalue=1e-84, Organism=Homo sapiens, GI25952152, Length=478, Percent_Identity=35.9832635983264, Blast_Score=296, Evalue=2e-80, Organism=Homo sapiens, GI25777726, Length=477, Percent_Identity=36.8972746331237, Blast_Score=293, Evalue=3e-79, Organism=Homo sapiens, GI301500698, Length=281, Percent_Identity=42.3487544483986, Blast_Score=238, Evalue=7e-63, Organism=Homo sapiens, GI4507229, Length=476, Percent_Identity=34.0336134453782, Blast_Score=231, Evalue=1e-60, Organism=Homo sapiens, GI25777721, Length=489, Percent_Identity=33.1288343558282, Blast_Score=223, Evalue=4e-58, Organism=Homo sapiens, GI11095441, Length=478, Percent_Identity=29.9163179916318, Blast_Score=216, Evalue=4e-56, Organism=Homo sapiens, GI188035924, Length=460, Percent_Identity=28.0434782608696, Blast_Score=179, Evalue=4e-45, Organism=Homo sapiens, GI310128093, Length=452, Percent_Identity=28.3185840707965, Blast_Score=178, Evalue=8e-45, Organism=Homo sapiens, GI310128103, Length=452, Percent_Identity=28.3185840707965, Blast_Score=178, Evalue=1e-44, Organism=Homo sapiens, GI223972651, Length=467, Percent_Identity=28.051391862955, Blast_Score=161, Evalue=2e-39, Organism=Homo sapiens, GI310128091, Length=335, Percent_Identity=31.9402985074627, Blast_Score=157, Evalue=3e-38, Organism=Homo sapiens, GI206597441, Length=353, Percent_Identity=31.1614730878187, Blast_Score=155, Evalue=6e-38, Organism=Homo sapiens, GI206597439, Length=353, Percent_Identity=31.1614730878187, Blast_Score=155, Evalue=6e-38, Organism=Homo sapiens, GI22907049, Length=353, Percent_Identity=31.1614730878187, Blast_Score=155, Evalue=6e-38, Organism=Homo sapiens, GI73466520, Length=340, Percent_Identity=29.1176470588235, Blast_Score=149, Evalue=4e-36, Organism=Homo sapiens, GI4557303, Length=340, Percent_Identity=29.1176470588235, Blast_Score=149, Evalue=5e-36, Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=31.4984709480122, Blast_Score=141, Evalue=1e-33, Organism=Homo sapiens, GI71773324, Length=405, Percent_Identity=27.1604938271605, Blast_Score=137, Evalue=2e-32, Organism=Homo sapiens, GI73695881, Length=363, Percent_Identity=26.4462809917355, Blast_Score=130, Evalue=2e-30, Organism=Homo sapiens, GI73695879, Length=363, Percent_Identity=26.4462809917355, Blast_Score=130, Evalue=2e-30, Organism=Homo sapiens, GI4502043, Length=341, Percent_Identity=27.5659824046921, Blast_Score=130, Evalue=3e-30, Organism=Homo sapiens, GI238814371, Length=341, Percent_Identity=27.5659824046921, Blast_Score=130, Evalue=3e-30, Organism=Homo sapiens, GI310128097, Length=250, Percent_Identity=33.2, Blast_Score=130, Evalue=4e-30, Organism=Homo sapiens, GI238859541, Length=459, Percent_Identity=25.9259259259259, Blast_Score=127, Evalue=2e-29, Organism=Homo sapiens, GI25777736, Length=459, Percent_Identity=25.9259259259259, Blast_Score=127, Evalue=2e-29, Organism=Homo sapiens, GI25777734, Length=459, Percent_Identity=25.9259259259259, Blast_Score=127, Evalue=2e-29, Organism=Homo sapiens, GI310128095, Length=312, Percent_Identity=29.4871794871795, Blast_Score=120, Evalue=2e-27, Organism=Homo sapiens, GI310128087, Length=452, Percent_Identity=23.8938053097345, Blast_Score=107, Evalue=2e-23, Organism=Homo sapiens, GI223972653, Length=183, Percent_Identity=30.6010928961749, Blast_Score=87, Evalue=3e-17, Organism=Homo sapiens, GI310128099, Length=215, Percent_Identity=23.7209302325581, Blast_Score=66, Evalue=7e-11, Organism=Homo sapiens, GI310128101, Length=215, Percent_Identity=23.7209302325581, Blast_Score=66, Evalue=8e-11, Organism=Escherichia coli, GI1787558, Length=474, Percent_Identity=41.1392405063291, Blast_Score=361, Evalue=1e-101, Organism=Escherichia coli, GI87082295, Length=494, Percent_Identity=37.0445344129555, Blast_Score=310, Evalue=2e-85, Organism=Escherichia coli, GI1786504, Length=483, Percent_Identity=37.4741200828157, Blast_Score=309, Evalue=3e-85, Organism=Escherichia coli, GI87081896, Length=481, Percent_Identity=37.8378378378378, Blast_Score=304, Evalue=1e-83, Organism=Escherichia coli, GI1789015, Length=481, Percent_Identity=35.7588357588358, Blast_Score=288, Evalue=5e-79, Organism=Escherichia coli, GI1787715, Length=413, Percent_Identity=38.9830508474576, Blast_Score=280, Evalue=2e-76, Organism=Escherichia coli, GI1787684, Length=486, Percent_Identity=32.3045267489712, Blast_Score=241, Evalue=1e-64, Organism=Escherichia coli, GI87081926, Length=451, Percent_Identity=31.0421286031042, Blast_Score=213, Evalue=2e-56, Organism=Escherichia coli, GI1788042, Length=454, Percent_Identity=27.3127753303965, Blast_Score=157, Evalue=1e-39, Organism=Escherichia coli, GI1787250, Length=433, Percent_Identity=27.9445727482679, Blast_Score=139, Evalue=3e-34, Organism=Escherichia coli, GI1787653, Length=298, Percent_Identity=30.2013422818792, Blast_Score=94, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562198, Length=476, Percent_Identity=42.0168067226891, Blast_Score=354, Evalue=5e-98, Organism=Caenorhabditis elegans, GI25144435, Length=480, Percent_Identity=41.0416666666667, Blast_Score=347, Evalue=1e-95, Organism=Caenorhabditis elegans, GI17551164, Length=484, Percent_Identity=38.4297520661157, Blast_Score=319, Evalue=2e-87, Organism=Caenorhabditis elegans, GI32564736, Length=418, Percent_Identity=41.6267942583732, Blast_Score=314, Evalue=8e-86, Organism=Caenorhabditis elegans, GI133930964, Length=479, Percent_Identity=37.5782881002088, Blast_Score=312, Evalue=3e-85, Organism=Caenorhabditis elegans, GI25143876, Length=483, Percent_Identity=35.1966873706004, Blast_Score=305, Evalue=3e-83, Organism=Caenorhabditis elegans, GI25143874, Length=482, Percent_Identity=35.2697095435685, Blast_Score=304, Evalue=5e-83, Organism=Caenorhabditis elegans, GI71995606, Length=483, Percent_Identity=36.4389233954451, Blast_Score=295, Evalue=4e-80, Organism=Caenorhabditis elegans, GI17534119, Length=481, Percent_Identity=34.5114345114345, Blast_Score=270, Evalue=9e-73, Organism=Caenorhabditis elegans, GI71995613, Length=419, Percent_Identity=36.7541766109785, Blast_Score=247, Evalue=8e-66, Organism=Caenorhabditis elegans, GI71986308, Length=478, Percent_Identity=28.8702928870293, Blast_Score=192, Evalue=5e-49, Organism=Caenorhabditis elegans, GI115534176, Length=478, Percent_Identity=28.0334728033473, Blast_Score=176, Evalue=3e-44, Organism=Caenorhabditis elegans, GI32566756, Length=342, Percent_Identity=31.2865497076023, Blast_Score=140, Evalue=2e-33, Organism=Caenorhabditis elegans, GI25146391, Length=342, Percent_Identity=31.2865497076023, Blast_Score=140, Evalue=2e-33, Organism=Caenorhabditis elegans, GI25146394, Length=342, Percent_Identity=31.2865497076023, Blast_Score=140, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17564084, Length=341, Percent_Identity=29.6187683284457, Blast_Score=132, Evalue=4e-31, Organism=Caenorhabditis elegans, GI17534447, Length=425, Percent_Identity=26.5882352941176, Blast_Score=130, Evalue=2e-30, Organism=Caenorhabditis elegans, GI32564151, Length=393, Percent_Identity=26.2086513994911, Blast_Score=124, Evalue=1e-28, Organism=Caenorhabditis elegans, GI115532534, Length=369, Percent_Identity=26.8292682926829, Blast_Score=123, Evalue=2e-28, Organism=Caenorhabditis elegans, GI71990744, Length=269, Percent_Identity=26.7657992565056, Blast_Score=79, Evalue=6e-15, Organism=Saccharomyces cerevisiae, GI6320917, Length=475, Percent_Identity=41.8947368421053, Blast_Score=369, Evalue=1e-103, Organism=Saccharomyces cerevisiae, GI6324950, Length=474, Percent_Identity=40.7172995780591, Blast_Score=368, Evalue=1e-102, Organism=Saccharomyces cerevisiae, GI6323822, Length=488, Percent_Identity=38.7295081967213, Blast_Score=328, Evalue=1e-90, Organism=Saccharomyces cerevisiae, GI6325196, Length=480, Percent_Identity=37.2916666666667, Blast_Score=319, Evalue=7e-88, Organism=Saccharomyces cerevisiae, GI6323821, Length=487, Percent_Identity=36.5503080082135, Blast_Score=308, Evalue=2e-84, Organism=Saccharomyces cerevisiae, GI6319478, Length=492, Percent_Identity=32.520325203252, Blast_Score=256, Evalue=4e-69, Organism=Saccharomyces cerevisiae, GI6321828, Length=471, Percent_Identity=25.9023354564756, Blast_Score=151, Evalue=3e-37, Organism=Saccharomyces cerevisiae, GI6321826, Length=485, Percent_Identity=24.1237113402062, Blast_Score=105, Evalue=1e-23, Organism=Saccharomyces cerevisiae, GI6323757, Length=324, Percent_Identity=25.3086419753086, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI20129399, Length=475, Percent_Identity=42.1052631578947, Blast_Score=360, Evalue=1e-99, Organism=Drosophila melanogaster, GI24650465, Length=485, Percent_Identity=41.0309278350515, Blast_Score=357, Evalue=1e-98, Organism=Drosophila melanogaster, GI24585660, Length=494, Percent_Identity=37.6518218623482, Blast_Score=327, Evalue=1e-89, Organism=Drosophila melanogaster, GI281362580, Length=484, Percent_Identity=35.7438016528926, Blast_Score=307, Evalue=1e-83, Organism=Drosophila melanogaster, GI62472918, Length=484, Percent_Identity=35.7438016528926, Blast_Score=307, Evalue=1e-83, Organism=Drosophila melanogaster, GI62472926, Length=484, Percent_Identity=35.7438016528926, Blast_Score=307, Evalue=1e-83, Organism=Drosophila melanogaster, GI62472936, Length=484, Percent_Identity=35.7438016528926, Blast_Score=307, Evalue=1e-83, Organism=Drosophila melanogaster, GI21356737, Length=484, Percent_Identity=35.7438016528926, Blast_Score=307, Evalue=1e-83, Organism=Drosophila melanogaster, GI24638878, Length=474, Percent_Identity=27.4261603375527, Blast_Score=182, Evalue=4e-46, Organism=Drosophila melanogaster, GI24638876, Length=474, Percent_Identity=27.4261603375527, Blast_Score=182, Evalue=4e-46, Organism=Drosophila melanogaster, GI24666674, Length=468, Percent_Identity=26.4957264957265, Blast_Score=164, Evalue=2e-40, Organism=Drosophila melanogaster, GI24668425, Length=469, Percent_Identity=25.7995735607676, Blast_Score=136, Evalue=3e-32, Organism=Drosophila melanogaster, GI24668417, Length=469, Percent_Identity=25.7995735607676, Blast_Score=136, Evalue=3e-32, Organism=Drosophila melanogaster, GI24668413, Length=469, Percent_Identity=25.7995735607676, Blast_Score=136, Evalue=3e-32, Organism=Drosophila melanogaster, GI281360301, Length=448, Percent_Identity=26.1160714285714, Blast_Score=126, Evalue=3e-29, Organism=Drosophila melanogaster, GI281360299, Length=448, Percent_Identity=26.1160714285714, Blast_Score=126, Evalue=3e-29, Organism=Drosophila melanogaster, GI281360297, Length=448, Percent_Identity=26.1160714285714, Blast_Score=126, Evalue=3e-29, Organism=Drosophila melanogaster, GI281360295, Length=448, Percent_Identity=26.1160714285714, Blast_Score=126, Evalue=3e-29, Organism=Drosophila melanogaster, GI24586250, Length=448, Percent_Identity=26.1160714285714, Blast_Score=126, Evalue=3e-29, Organism=Drosophila melanogaster, GI45552499, Length=448, Percent_Identity=25.8928571428571, Blast_Score=125, Evalue=5e-29, Organism=Drosophila melanogaster, GI281360303, Length=448, Percent_Identity=25.8928571428571, Blast_Score=125, Evalue=6e-29, Organism=Drosophila melanogaster, GI28574525, Length=436, Percent_Identity=24.3119266055046, Blast_Score=87, Evalue=4e-17, Organism=Drosophila melanogaster, GI28571806, Length=357, Percent_Identity=23.249299719888, Blast_Score=81, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571802, Length=357, Percent_Identity=23.249299719888, Blast_Score=81, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571800, Length=357, Percent_Identity=23.249299719888, Blast_Score=81, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571798, Length=357, Percent_Identity=23.249299719888, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI28571796, Length=357, Percent_Identity=23.249299719888, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI28571794, Length=357, Percent_Identity=23.249299719888, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI281360293, Length=264, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=3e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016161 - InterPro: IPR016163 - InterPro: IPR016160 - InterPro: IPR016162 - InterPro: IPR015590 - InterPro: IPR011985 [H]
Pfam domain/function: PF00171 Aldedh [H]
EC number: 1.2.1.60
Molecular weight: Translated: 53996; Mature: 53865
Theoretical pI: Translated: 5.49; Mature: 5.49
Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTANRRPEGVPQRIQHFIGGKLVDSLADTWFDVIDPVTNQPYAQAAAGQADDVDRAVAAA CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHH KVAFRTGPWPNMQARSRSRVLNRIADAIESRDARLAELESFDSGLPITQALGQARRAAEN HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH FRFFADLVVAQADDAYKVPGSQINYVNRKPKGVAGLITPWNTPFMLESWKLAPALASGCT HHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCHHHHCCCE VVLKPAEFTPLSAGLWADIFRDAGVPDGVFNLVNGIGEEAGDALVKHPDVRVISFTGESA EEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHCCHHHCCCCEEEEEECCCCC TGEIIFRNCATGLKGMSMELGGKSPAVVFADADLDAALDSTLFGVFSLNGERCTAGSRIL CCCEEEEHHHCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHEEEEECCCCEECCCCEEE VEEEIYDEFVERFAARAAGIVVGDPQDPRTEVGALVHPEHFAKVMSYIDVGKTEGRLLCG EHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHCCEECHHHHHHHHHHHHCCCCCCEEEEC GGRPAHLPQGNFVAPTAFADVEPNARIFQEEIFGPVVALSRFQTEEQALALANGVKYGLA CCCCCCCCCCCEECCCEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHE AYIWTNDLKRAHRFAQNVDSGMVWVNSHNVRDLRTPFGGVKASGLGHEGGYRSLDFYTDQ EEEEHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCEEEECCC QAVHITLGDVHTPRFGITAR CEEEEEECCCCCCCCCCCCC >Mature Secondary Structure TANRRPEGVPQRIQHFIGGKLVDSLADTWFDVIDPVTNQPYAQAAAGQADDVDRAVAAA CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHH KVAFRTGPWPNMQARSRSRVLNRIADAIESRDARLAELESFDSGLPITQALGQARRAAEN HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH FRFFADLVVAQADDAYKVPGSQINYVNRKPKGVAGLITPWNTPFMLESWKLAPALASGCT HHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCHHHHCCCE VVLKPAEFTPLSAGLWADIFRDAGVPDGVFNLVNGIGEEAGDALVKHPDVRVISFTGESA EEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHCCHHHCCCCEEEEEECCCCC TGEIIFRNCATGLKGMSMELGGKSPAVVFADADLDAALDSTLFGVFSLNGERCTAGSRIL CCCEEEEHHHCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHEEEEECCCCEECCCCEEE VEEEIYDEFVERFAARAAGIVVGDPQDPRTEVGALVHPEHFAKVMSYIDVGKTEGRLLCG EHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHCCEECHHHHHHHHHHHHCCCCCCEEEEC GGRPAHLPQGNFVAPTAFADVEPNARIFQEEIFGPVVALSRFQTEEQALALANGVKYGLA CCCCCCCCCCCEECCCEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHE AYIWTNDLKRAHRFAQNVDSGMVWVNSHNVRDLRTPFGGVKASGLGHEGGYRSLDFYTDQ EEEEHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCEEEECCC QAVHITLGDVHTPRFGITAR CEEEEEECCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+
Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7737515 [H]