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The map label for this gene is yvbU [H]

Identifier: 119868686

GI number: 119868686

Start: 2785752

End: 2786600

Strand: Direct

Name: yvbU [H]

Synonym: Mkms_2653

Alternate gene names: 119868686

Gene position: 2785752-2786600 (Clockwise)

Preceding gene: 119868684

Following gene: 119868687

Centisome position: 48.56

GC content: 66.67

Gene sequence:

>849_bases
ATGACGGTGGGTTTCACGCTCAAGCAACTCGAGTACTTCTGTGCGGTCGCCGAGCACGGCTCGTTCAGCGCCGCCGGCGC
CCGATTGCACGTCTCCCCCTCGGCTGTGGCCTCCTCGGTCGGTGATCTCGAACGCGTCCTGGCCACCCAACTGCTGGTGC
GTCGCAAGGCTCACGGGGTCTCGCTGACCGCCGCAGGCTCCCACACGTTGAAGCGAGCCCGCATTCTGCTCGCCGAGGCA
CGTGAAGTGGAACTCGTGCGAGGCGAGGACGGTAGCCGGCTGGCCGGGCCGGTCTCGATCGGATGCTATTCGACGCTGGC
CGCCTCGGTACTTCCCGGTCTACTCGAGGAGTTCTCCGCCCTGCACCCCGACGACGACCTGTCCTTCGTCGACGGCGGTA
TGGACGACCTGGTGCCGATGCTGCGCCGGTCGGCGCTCGACCTCATCATCACCTACCGCATCAATCTTCCGGTCGGCGTG
CAGGAGGCTGTCCTCTACGAGTGCGATCTGCACGCACTGCTACCCGGCGGGCACCGACTGGCTGAGGAGTCGGCCATCGA
CGTCCAGGAGCTCGCCGGCGAGAACTTGATCTTGCTAGACCTGCCGCCCAGTGGCAGGCACACCCTCGACCTGCTCAGTG
CCGCCGGGATAACCCCCACCATCCGGCACCGAACGCAGAACTTCGAGCTGGTGCGATCCCTGGTGGCCCGCGGTCTCGGC
TACAGCCTGCTCATCCAGAAGCCGCGTATTACCCACAGTTATGAGGGCCTCTCTCTGGTGACTCGGCCCTCCAACCCCGG
CTGTCGCGGGAGGCCGTCGTGTGCATCTGGCCCGCGGCGACCCGGCTGA

Upstream 100 bases:

>100_bases
TCGTCCATGGCTTCATCCTCTCCTACCCAGGCGCCTTGGGTAAGCAGCGAAAACCACTGAATATCCCCGGGTTTTCGCGT
CTTCAACGGGGTCAGCATCC

Downstream 100 bases:

>100_bases
CCAACCGGGCCCGCGCGTTGGTCGACTACGCGAGGGAAACCTCCGCGCCGGCTTTGACGAAGACCTCGTCGACCCCACAG
ACTGACAATCTATGAGTGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTVGFTLKQLEYFCAVAEHGSFSAAGARLHVSPSAVASSVGDLERVLATQLLVRRKAHGVSLTAAGSHTLKRARILLAEA
REVELVRGEDGSRLAGPVSIGCYSTLAASVLPGLLEEFSALHPDDDLSFVDGGMDDLVPMLRRSALDLIITYRINLPVGV
QEAVLYECDLHALLPGGHRLAEESAIDVQELAGENLILLDLPPSGRHTLDLLSAAGITPTIRHRTQNFELVRSLVARGLG
YSLLIQKPRITHSYEGLSLVTRPSNPGCRGRPSCASGPRRPG

Sequences:

>Translated_282_residues
MTVGFTLKQLEYFCAVAEHGSFSAAGARLHVSPSAVASSVGDLERVLATQLLVRRKAHGVSLTAAGSHTLKRARILLAEA
REVELVRGEDGSRLAGPVSIGCYSTLAASVLPGLLEEFSALHPDDDLSFVDGGMDDLVPMLRRSALDLIITYRINLPVGV
QEAVLYECDLHALLPGGHRLAEESAIDVQELAGENLILLDLPPSGRHTLDLLSAAGITPTIRHRTQNFELVRSLVARGLG
YSLLIQKPRITHSYEGLSLVTRPSNPGCRGRPSCASGPRRPG
>Mature_281_residues
TVGFTLKQLEYFCAVAEHGSFSAAGARLHVSPSAVASSVGDLERVLATQLLVRRKAHGVSLTAAGSHTLKRARILLAEAR
EVELVRGEDGSRLAGPVSIGCYSTLAASVLPGLLEEFSALHPDDDLSFVDGGMDDLVPMLRRSALDLIITYRINLPVGVQ
EAVLYECDLHALLPGGHRLAEESAIDVQELAGENLILLDLPPSGRHTLDLLSAAGITPTIRHRTQNFELVRSLVARGLGY
SLLIQKPRITHSYEGLSLVTRPSNPGCRGRPSCASGPRRPG

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=241, Percent_Identity=25.7261410788382, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788887, Length=261, Percent_Identity=28.735632183908, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787601, Length=152, Percent_Identity=32.2368421052632, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790262, Length=236, Percent_Identity=27.9661016949153, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787879, Length=252, Percent_Identity=30.1587301587302, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367136, Length=272, Percent_Identity=27.9411764705882, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=31.8367346938775, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789204, Length=265, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787530, Length=241, Percent_Identity=25.7261410788382, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=28.0487804878049, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30163; Mature: 30032

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGFTLKQLEYFCAVAEHGSFSAAGARLHVSPSAVASSVGDLERVLATQLLVRRKAHGV
CCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCE
SLTAAGSHTLKRARILLAEAREVELVRGEDGSRLAGPVSIGCYSTLAASVLPGLLEEFSA
EEEECCCHHHHHHHHHHHHCCEEEEEECCCCCEECCCEEHHHHHHHHHHHHHHHHHHHHH
LHPDDDLSFVDGGMDDLVPMLRRSALDLIITYRINLPVGVQEAVLYECDLHALLPGGHRL
CCCCCCCHHHCCCHHHHHHHHHHHHEEEEEEEEECCCCCHHHHHEEECCCCEECCCCHHH
AEESAIDVQELAGENLILLDLPPSGRHTLDLLSAAGITPTIRHRTQNFELVRSLVARGLG
HHHHCCCHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHCCC
YSLLIQKPRITHSYEGLSLVTRPSNPGCRGRPSCASGPRRPG
EEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVGFTLKQLEYFCAVAEHGSFSAAGARLHVSPSAVASSVGDLERVLATQLLVRRKAHGV
CCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCE
SLTAAGSHTLKRARILLAEAREVELVRGEDGSRLAGPVSIGCYSTLAASVLPGLLEEFSA
EEEECCCHHHHHHHHHHHHCCEEEEEECCCCCEECCCEEHHHHHHHHHHHHHHHHHHHHH
LHPDDDLSFVDGGMDDLVPMLRRSALDLIITYRINLPVGVQEAVLYECDLHALLPGGHRL
CCCCCCCHHHCCCHHHHHHHHHHHHEEEEEEEEECCCCCHHHHHEEECCCCEECCCCHHH
AEESAIDVQELAGENLILLDLPPSGRHTLDLLSAAGITPTIRHRTQNFELVRSLVARGLG
HHHHCCCHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHCCC
YSLLIQKPRITHSYEGLSLVTRPSNPGCRGRPSCASGPRRPG
EEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]