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The map label for this gene is potC [H]

Identifier: 119868644

GI number: 119868644

Start: 2743543

End: 2744400

Strand: Reverse

Name: potC [H]

Synonym: Mkms_2609

Alternate gene names: 119868644

Gene position: 2744400-2743543 (Counterclockwise)

Preceding gene: 119868645

Following gene: 119868642

Centisome position: 47.83

GC content: 65.73

Gene sequence:

>858_bases
ATGACCACCCAAGCCGGCGCCGCGGTCGCCGCCGCGGCCGAGCAGCCGCCCCGACCGAAAACCGTTCGGGGAACTCCGAA
GTGGGGCGACTGGAGCCTGCGGATCGTCGCCGGCCTGGTGCTGCTGTACCTGTTCATCCCGATCTTCGTGATCGTGCTGT
TCTCGTTCAACGACCCCAAGGGGAAGTTCAACTACAGCTGGCAGGGCTTCACGCTCGACAACTGGCTCGACCCGTTCAAG
TACCCGGCGCTGACGAACGCGATGAAGTTGAGCCTCAACGTCGCCGGGGTGTCGACGCTCATCGCGCTGGTACTCGGCAC
GCTGGTGGCCATCGCGCTGGTGCGTCAACGCTGGCGCGGACAGCGTGCCGTCGACACGTTCCTGGTGCTTCCGCTCACCG
CGCCCGAGGTGGTGATGGGCGCATCGCTGCTGGTGCTGTTCCTCGACCTGGGCTGGGCGACCGGATACGTCACGATCGTG
TTGGCCCACATCGCCTTCGAGGTCAGCTTCATCGCGATGACGGTGCGCGCCCGGGTGCGGGGGTTCGACTGGACACTCGA
GGATGCGTCGATGGATCTGGGCGCGAGTCCGACCCGGACCTTCTTCAAGGTGACGCTGCCGCTGATCGTCCCCGGCATCG
TCGCCGCGGCGATGCTCTCGTTCGCGCTGTCGCTCGACGACTTCATCATCACCTATTTCGTCAGCGGGTCGACCGTGACG
TATCCGCTCTACGTCAACGCGGCGGTCAAGGCCGCGGTGCCACCGCAGATCAACGTGATCGCGACGGCGATCCTCGTGGT
CAGCCTGATCTTGTTGGCGGCGGGCACGCTCTACCGCCGCAAGCGCATCGACGTCTAG

Upstream 100 bases:

>100_bases
AGGACTATCCGGCGGCCGCGGCGCTGAGCCTGGTTTTGATGGGCACGATCCTGGCCGGTGTGCTGCTCTACACGCGGGCG
CTGGGCACGGAGGACCTGGT

Downstream 100 bases:

>100_bases
GCCGGTTTCCGACGAAACAGCATTCCCTGTCGTCAAGCGCCCCGCTTGGCAGCAGGGAATGCTGTTTCGCGAGAGCGCGG
CGTCAGCCGACCTCGACCGG

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTTQAGAAVAAAAEQPPRPKTVRGTPKWGDWSLRIVAGLVLLYLFIPIFVIVLFSFNDPKGKFNYSWQGFTLDNWLDPFK
YPALTNAMKLSLNVAGVSTLIALVLGTLVAIALVRQRWRGQRAVDTFLVLPLTAPEVVMGASLLVLFLDLGWATGYVTIV
LAHIAFEVSFIAMTVRARVRGFDWTLEDASMDLGASPTRTFFKVTLPLIVPGIVAAAMLSFALSLDDFIITYFVSGSTVT
YPLYVNAAVKAAVPPQINVIATAILVVSLILLAAGTLYRRKRIDV

Sequences:

>Translated_285_residues
MTTQAGAAVAAAAEQPPRPKTVRGTPKWGDWSLRIVAGLVLLYLFIPIFVIVLFSFNDPKGKFNYSWQGFTLDNWLDPFK
YPALTNAMKLSLNVAGVSTLIALVLGTLVAIALVRQRWRGQRAVDTFLVLPLTAPEVVMGASLLVLFLDLGWATGYVTIV
LAHIAFEVSFIAMTVRARVRGFDWTLEDASMDLGASPTRTFFKVTLPLIVPGIVAAAMLSFALSLDDFIITYFVSGSTVT
YPLYVNAAVKAAVPPQINVIATAILVVSLILLAAGTLYRRKRIDV
>Mature_284_residues
TTQAGAAVAAAAEQPPRPKTVRGTPKWGDWSLRIVAGLVLLYLFIPIFVIVLFSFNDPKGKFNYSWQGFTLDNWLDPFKY
PALTNAMKLSLNVAGVSTLIALVLGTLVAIALVRQRWRGQRAVDTFLVLPLTAPEVVMGASLLVLFLDLGWATGYVTIVL
AHIAFEVSFIAMTVRARVRGFDWTLEDASMDLGASPTRTFFKVTLPLIVPGIVAAAMLSFALSLDDFIITYFVSGSTVTY
PLYVNAAVKAAVPPQINVIATAILVVSLILLAAGTLYRRKRIDV

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=229, Percent_Identity=38.4279475982533, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787081, Length=231, Percent_Identity=38.5281385281385, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787714, Length=250, Percent_Identity=38.4, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788764, Length=168, Percent_Identity=29.7619047619048, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30993; Mature: 30862

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQAGAAVAAAAEQPPRPKTVRGTPKWGDWSLRIVAGLVLLYLFIPIFVIVLFSFNDPK
CCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKFNYSWQGFTLDNWLDPFKYPALTNAMKLSLNVAGVSTLIALVLGTLVAIALVRQRWRG
CCEECEECCCCHHHCCCCCCCCHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
QRAVDTFLVLPLTAPEVVMGASLLVLFLDLGWATGYVTIVLAHIAFEVSFIAMTVRARVR
CHHHHEEEEEECCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFDWTLEDASMDLGASPTRTFFKVTLPLIVPGIVAAAMLSFALSLDDFIITYFVSGSTVT
CCCEEECCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEE
YPLYVNAAVKAAVPPQINVIATAILVVSLILLAAGTLYRRKRIDV
EEEEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTQAGAAVAAAAEQPPRPKTVRGTPKWGDWSLRIVAGLVLLYLFIPIFVIVLFSFNDPK
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKFNYSWQGFTLDNWLDPFKYPALTNAMKLSLNVAGVSTLIALVLGTLVAIALVRQRWRG
CCEECEECCCCHHHCCCCCCCCHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
QRAVDTFLVLPLTAPEVVMGASLLVLFLDLGWATGYVTIVLAHIAFEVSFIAMTVRARVR
CHHHHEEEEEECCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFDWTLEDASMDLGASPTRTFFKVTLPLIVPGIVAAAMLSFALSLDDFIITYFVSGSTVT
CCCEEECCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEE
YPLYVNAAVKAAVPPQINVIATAILVVSLILLAAGTLYRRKRIDV
EEEEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]