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The map label for this gene is acnR [H]

Identifier: 119868528

GI number: 119868528

Start: 2613626

End: 2614204

Strand: Reverse

Name: acnR [H]

Synonym: Mkms_2493

Alternate gene names: 119868528

Gene position: 2614204-2613626 (Counterclockwise)

Preceding gene: 119868529

Following gene: 119868514

Centisome position: 45.57

GC content: 69.26

Gene sequence:

>579_bases
ATGCCCCGGGTCACCGACGACCATCTGGCGGCGCGCCGCCGTCAGATCCTCGACGGCGCCCGGCGCTGCTTCGCGCGATA
CGGATACGACAAGGCGACCGTGCGGCGGCTCGAAGACACCATCGGGCTGTCGCGCGGCGCCATCTTCCACCACTTCCGGG
ACAAGGACACGTTGTTCTTCGAACTGGCCCGCGAAGACGCCGAGCGGATGGCCGACGTCGCCTCCCGCGAGGGGTTGATC
CAGGTCATGCGTGACCTGTTGGCTGCGCCCGACCAGTTCGACTGGCTGGCCACCCGGTTGGAGATCGCGCGCAAGCTGCG
CAACGATCCGGTGTTCCATAAGGGGTGGGAGGAGCGGTCCGCCGAGTTGTCCGCCGCTACCACGGCGCGGCTGCACCGGC
AGAAGGAGGCCGGCCGACTACGCGACGACGTTCCCAGCGAGGTGCTGCAGACCTACCTCGACCTGGTTCTCGACGGGCTG
GTCGCCCGGCTGGCCTCCGGCGACGACCCGAAGAAGCTGGGCGCGGTTCTCGACCTCGTCGAGGCGTCCGTGCGCCAGCA
GGGCTCCAGCGTCAGCTGA

Upstream 100 bases:

>100_bases
CCCCGGTGAGGCCGACTACTACCGCAACGGCGGCATCCTGCAGTACGTGCTGCGCAACATGCTGAAGACCAAGTAACCAG
CGCTGGCAGGAGCTGGACTG

Downstream 100 bases:

>100_bases
CGCTGGAGCGACGCGAACGGTGATTCGGCCCACCGCGACTGCGCATCGTCGTACCCGACTCGCGCAGCATGCTGTGGATC
GACCCGTACGAACGGCCGGT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MPRVTDDHLAARRRQILDGARRCFARYGYDKATVRRLEDTIGLSRGAIFHHFRDKDTLFFELAREDAERMADVASREGLI
QVMRDLLAAPDQFDWLATRLEIARKLRNDPVFHKGWEERSAELSAATTARLHRQKEAGRLRDDVPSEVLQTYLDLVLDGL
VARLASGDDPKKLGAVLDLVEASVRQQGSSVS

Sequences:

>Translated_192_residues
MPRVTDDHLAARRRQILDGARRCFARYGYDKATVRRLEDTIGLSRGAIFHHFRDKDTLFFELAREDAERMADVASREGLI
QVMRDLLAAPDQFDWLATRLEIARKLRNDPVFHKGWEERSAELSAATTARLHRQKEAGRLRDDVPSEVLQTYLDLVLDGL
VARLASGDDPKKLGAVLDLVEASVRQQGSSVS
>Mature_191_residues
PRVTDDHLAARRRQILDGARRCFARYGYDKATVRRLEDTIGLSRGAIFHHFRDKDTLFFELAREDAERMADVASREGLIQ
VMRDLLAAPDQFDWLATRLEIARKLRNDPVFHKGWEERSAELSAATTARLHRQKEAGRLRDDVPSEVLQTYLDLVLDGLV
ARLASGDDPKKLGAVLDLVEASVRQQGSSVS

Specific function: Represses the aconitase gene acn [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21755; Mature: 21624

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVTDDHLAARRRQILDGARRCFARYGYDKATVRRLEDTIGLSRGAIFHHFRDKDTLFF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
ELAREDAERMADVASREGLIQVMRDLLAAPDQFDWLATRLEIARKLRNDPVFHKGWEERS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AELSAATTARLHRQKEAGRLRDDVPSEVLQTYLDLVLDGLVARLASGDDPKKLGAVLDLV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EASVRQQGSSVS
HHHHHHCCCCCC
>Mature Secondary Structure 
PRVTDDHLAARRRQILDGARRCFARYGYDKATVRRLEDTIGLSRGAIFHHFRDKDTLFF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
ELAREDAERMADVASREGLIQVMRDLLAAPDQFDWLATRLEIARKLRNDPVFHKGWEERS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
AELSAATTARLHRQKEAGRLRDDVPSEVLQTYLDLVLDGLVARLASGDDPKKLGAVLDLV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EASVRQQGSSVS
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910 [H]