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The map label for this gene is lgrD [H]

Identifier: 119868354

GI number: 119868354

Start: 2424377

End: 2427901

Strand: Reverse

Name: lgrD [H]

Synonym: Mkms_2318

Alternate gene names: 119868354

Gene position: 2427901-2424377 (Counterclockwise)

Preceding gene: 119868356

Following gene: 119868352

Centisome position: 42.32

GC content: 69.02

Gene sequence:

>3525_bases
ATGTCCACCGAGACCCGTGAAGCGCGCCTGCAGCAGCGCATCGCGCATCTGTTCACCACCGACCCGCAGTTCGCCGCCGC
CCGGCCCGACCCCCGGATCAGCGATGCCGTCGACCGCGATGACACGCGGCTGACCGCCATCGTCTCCGCGGTCATGTCGG
GGTACGCCGACCGGCCGGCACTCGGGCAGCGCGCCGCCGAATTCGTCACCGACCCGCAGACCGGCCGCACCACGATGGAG
CTGCTCCCCCGCTTCGACACCATCACCTACCGGGAGCTGCTCGACCGCGTCCGGGCGCTCACCAACGCGTGGCACGCCGA
CGGGGTGCGCCCCGGCGACCGTGTCGCAATCCTCGGATTCACCGGCATCGACTACACCGTGGTCGACCTCGCCCTGATCC
AGCTCGGCGCGGTCGCGGTGCCGCTGCAGACCAGCGCCGCCGTGGAGGCGTTGCGCCCGATCGTGGCCGAGACCGAACCG
ATGCTCATCGCCACCGGCGTCGATCATGTCGACGCCGCCGCGGAACTCGCACTCACCGGCCACCGTCCGTCCCGGGTGGT
GGTCTTCGACCACCGCGAGCAGGTCGACGACGAACGCGACGCGGTGCGGGCCGCGACGGCCAGGCTGGGAGACGCCGTCC
CCGTCGAGACACTCGCCGAGGTGTTGCGGCGGGGCGCCCATCTGCCCGCCGTGGCGCCGCACGTGTTCGACGAGGCCGAT
CCACTGCGGCTGCTGATCTACACTTCCGGCAGCGCCGGCGCCCCCAAGGGCGCGATGTATCCCGAGAGCAAGGTCGCCGG
CATGTGGCGCGCGTCGGCCAAGGCCGCCTGGAACAACGATCAGACAGCGATTCCGTCGATCACCCTGAACTTCCTGCCGA
TGAGCCACGTCATGGGTCGCGGCCTGCTGTGCGGCACGCTCAGCACCGGTGGCACCGCGTATTTCGCCGCCCGCAGCGAT
CTGTCGACGCTGCTCGAGGACCTGCGCCTGGTACGGCCCACCCAACTCAGCTTCGTGCCGCGGATCTGGGACATGCTCTT
CCAGGAGTTCGTCGGCGAGGTCGACCGGCGGGTGAACGACGGTGCGGACCGCCCCACCGCGGAGGCCGACGTGCTGGCCG
TACAGCGTCACGAGCTGCTCGGTGGCCGGTTCGTCACCGCGATGACCGGTTCGGCGCCCATCTCCCTCGAGATGAAGACA
TGGGTGGAGACCCTGCTCGACATGCACCTGGTCGAGGGTTACGGCTCGACGGAGGCCGGCGCGGTGTTCGTCGACGGCCA
CATCCAGCGCCCACCGGTGCTCGACTACAAACTCGTCGACGTCCCCGACCTCGGCTACTTCAGCACCGACCGGCCGCACC
CGCGCGGTGAGCTGCTGGTCCGCTCCACGCAGCTATTCCCCGGCTACTACAAACGTCCCGACGTCACCGCCGAGGTGTTC
GACGACGACGGCTTCTACCGCACGGGCGACATCGTCGCCGAGGTCGGCCCCGATCAGGTGCAGTACCTCGACCGCCGCAA
CAACGTGCTCAAACTCGCCCAGGGTGAGTTCGTCACCATCTCCAAACTCGAGGCGGTCTTCGCCGGCAGCGCCCTGGTCC
GCCAGATCTACGTGTACGGCAACAGTGCGCGCTCCTACCTGCTGGCCGTCGTCGTGCCGACCGACGATGCGGTGGCCCGG
CACGACCCGGCATCGCTCAAGACCGCGATCAGCGCCTCGCTGCAGCAGGCCGCGAAGACCGCCGGTCTGCAGTCCTACGA
GCTGCCGCGTGACTTCCTCGTCGAGACTCAACCGTTCACGCTGGAGAACGGACTACTGACCGGCATCCGCAAGCTGGCGC
GCCCGAAACTCAAGGCGCGCTACGGCGATCGGCTCGAGGCGCTCTACGTCGAACTGGTCGAAGGACAGGCAGGCGAATTG
CGCACCCTGCGCCGGGACGGCGCGAAGCGTCCGGTGGCCGAGACGGTCGGCCGCGCCGCGGCCGCGCTGCTCGGCGCCGC
CGCCGCCGACGTGCGCCCCGACGCGCACTTCACCGACCTCGGCGGAGACTCGTTGTCGGCGTTGACCTTCGGCAATCTGC
TGCAGGAGATCTTCGGCGTCGACGTCCCGGTCGGGGTGATCGTCAGCCCGGCGGCCGACCTGGCGTCGATCGCGGCGTAC
ATCGAGGCCGAACAGGCCTCGACCGGTAAGCGGCCGACCTACGCGTCGGTGCACGGGCGCGACGCCGAACAGGTACACGC
GCGCGACCTCACCCTGGACAAGTTCATCGACGCCGAAACACTCTCCGCTGCAACAGAACTGCCCGGCCCGAGCGGTGAGG
TGCGCACCGTGCTGCTGACCGGGGCCACCGGATTCCTCGGCCGCTACCTGGCGCTGGACTGGCTCGAACGGATGGCCCTG
GTCGACGGCAAGGTCATCTGCCTGGTCCGCGCGAAGGACGATGCGGCCGCCCGCAAACGCCTCGACGACACCTTCGACAG
CGGCGATCCGAAGCTGCTGGCGCACTACCGCAAGCTGGCCGCCGACCACCTCGAAGTGCTGGCCGGCGACAAGGGTGAGG
CGGATCTCGGGCTGCCGCATCCTGTCTGGCAGCGCCTGGCCGACACCGTCGACCTCATCGTCGACCCGGCCGCCCTGGTC
AACCACGTACTGCCGTACAGCCAGCTGTTCGGGCCCAACGCGCTGGGCACTGCCGAGCTGATCCGGCTTGCGCTCACCAC
CCGCATCAAACCGTTCACCTACGTGTCGACGATCGGCGTCGGCGCCGGTATCGAACCGGGCCGTTTCACCGAGGACGACG
ACATCCGGGTGATCAGCCCGACGCGGGCCGTCGACACCGGGTACGCCAACGGCTACGGCAACAGCAAGTGGGCCGGTGAG
GTGTTGTTGCGCGAGGCGCACGATCTGTGCGGGCTCCCCGTGGCGGTGTTCCGGTGCGACATGATCCTGGCCGACACCAC
CTACGCCGGCCAGCTCAACCTGCCGGACATGTTCACCCGGATGATGCTGAGCCTGGTGACCACGGGTATCGCGCCGAAAT
CGTTCCACCCACTCGACGCAAAGGGCCACCGGCAGAGCGCCCACTACGACGGGCTGCCGGTCGAGTTCGTCGCCGAATCG
ATCTCCGCGCTGGGAGCGCAGGCGGTCGACGAGGCGGGAACGGGTTTCGCCACCTACCACGTGATGAACCCCCACGACGA
CGGGATCGGCCTCGACGAATTCGTCGACTGGCTCGTCGAGGCGGGGTATCGCATCGACCGCATCGACTACTACGCGGCCT
GGCTGCAGCGGTTCGAAACCGCCCTGCGGGCGCTGCCCGAGCGCACTCGGCAGTACTCACTGCTCCCGCTGCTGCACAAC
TACCAGCGGCCTGCGCACCCGATCAACGGGGCGATGGCCCCGACCGACCGGTTCCGCGCTGCGGTGCAGGAGGCAAAGCT
CGGCCCGGACAAGGACATTCCCCACGTCACTCCAGCGGTGATCGTCAAGTACGCCACCGACCTGGAGCTGCTGGGCCTGA
TCTAG

Upstream 100 bases:

>100_bases
GACGAACAGCTCGGAATAAGATTAGTTTGGCTAACGTAGTATCTCAGGGTGCGCAGCGAGGCGCCGCCGGAAACCTGATC
GCCAGTCGTGAGGATTCGTC

Downstream 100 bases:

>100_bases
TCAGGCCACCACGCTCTCCACCCGGACGACCGGAGGGATGGCGAGCATGAGAAGTCCGGTCAGGCCGATCCAGGCGACCA
TGCTGTAGGCGCCCGGCAGT

Product: thioester reductase domain-containing protein

Products: NA

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1174; Mature: 1173

Protein sequence:

>1174_residues
MSTETREARLQQRIAHLFTTDPQFAAARPDPRISDAVDRDDTRLTAIVSAVMSGYADRPALGQRAAEFVTDPQTGRTTME
LLPRFDTITYRELLDRVRALTNAWHADGVRPGDRVAILGFTGIDYTVVDLALIQLGAVAVPLQTSAAVEALRPIVAETEP
MLIATGVDHVDAAAELALTGHRPSRVVVFDHREQVDDERDAVRAATARLGDAVPVETLAEVLRRGAHLPAVAPHVFDEAD
PLRLLIYTSGSAGAPKGAMYPESKVAGMWRASAKAAWNNDQTAIPSITLNFLPMSHVMGRGLLCGTLSTGGTAYFAARSD
LSTLLEDLRLVRPTQLSFVPRIWDMLFQEFVGEVDRRVNDGADRPTAEADVLAVQRHELLGGRFVTAMTGSAPISLEMKT
WVETLLDMHLVEGYGSTEAGAVFVDGHIQRPPVLDYKLVDVPDLGYFSTDRPHPRGELLVRSTQLFPGYYKRPDVTAEVF
DDDGFYRTGDIVAEVGPDQVQYLDRRNNVLKLAQGEFVTISKLEAVFAGSALVRQIYVYGNSARSYLLAVVVPTDDAVAR
HDPASLKTAISASLQQAAKTAGLQSYELPRDFLVETQPFTLENGLLTGIRKLARPKLKARYGDRLEALYVELVEGQAGEL
RTLRRDGAKRPVAETVGRAAAALLGAAAADVRPDAHFTDLGGDSLSALTFGNLLQEIFGVDVPVGVIVSPAADLASIAAY
IEAEQASTGKRPTYASVHGRDAEQVHARDLTLDKFIDAETLSAATELPGPSGEVRTVLLTGATGFLGRYLALDWLERMAL
VDGKVICLVRAKDDAAARKRLDDTFDSGDPKLLAHYRKLAADHLEVLAGDKGEADLGLPHPVWQRLADTVDLIVDPAALV
NHVLPYSQLFGPNALGTAELIRLALTTRIKPFTYVSTIGVGAGIEPGRFTEDDDIRVISPTRAVDTGYANGYGNSKWAGE
VLLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRMMLSLVTTGIAPKSFHPLDAKGHRQSAHYDGLPVEFVAES
ISALGAQAVDEAGTGFATYHVMNPHDDGIGLDEFVDWLVEAGYRIDRIDYYAAWLQRFETALRALPERTRQYSLLPLLHN
YQRPAHPINGAMAPTDRFRAAVQEAKLGPDKDIPHVTPAVIVKYATDLELLGLI

Sequences:

>Translated_1174_residues
MSTETREARLQQRIAHLFTTDPQFAAARPDPRISDAVDRDDTRLTAIVSAVMSGYADRPALGQRAAEFVTDPQTGRTTME
LLPRFDTITYRELLDRVRALTNAWHADGVRPGDRVAILGFTGIDYTVVDLALIQLGAVAVPLQTSAAVEALRPIVAETEP
MLIATGVDHVDAAAELALTGHRPSRVVVFDHREQVDDERDAVRAATARLGDAVPVETLAEVLRRGAHLPAVAPHVFDEAD
PLRLLIYTSGSAGAPKGAMYPESKVAGMWRASAKAAWNNDQTAIPSITLNFLPMSHVMGRGLLCGTLSTGGTAYFAARSD
LSTLLEDLRLVRPTQLSFVPRIWDMLFQEFVGEVDRRVNDGADRPTAEADVLAVQRHELLGGRFVTAMTGSAPISLEMKT
WVETLLDMHLVEGYGSTEAGAVFVDGHIQRPPVLDYKLVDVPDLGYFSTDRPHPRGELLVRSTQLFPGYYKRPDVTAEVF
DDDGFYRTGDIVAEVGPDQVQYLDRRNNVLKLAQGEFVTISKLEAVFAGSALVRQIYVYGNSARSYLLAVVVPTDDAVAR
HDPASLKTAISASLQQAAKTAGLQSYELPRDFLVETQPFTLENGLLTGIRKLARPKLKARYGDRLEALYVELVEGQAGEL
RTLRRDGAKRPVAETVGRAAAALLGAAAADVRPDAHFTDLGGDSLSALTFGNLLQEIFGVDVPVGVIVSPAADLASIAAY
IEAEQASTGKRPTYASVHGRDAEQVHARDLTLDKFIDAETLSAATELPGPSGEVRTVLLTGATGFLGRYLALDWLERMAL
VDGKVICLVRAKDDAAARKRLDDTFDSGDPKLLAHYRKLAADHLEVLAGDKGEADLGLPHPVWQRLADTVDLIVDPAALV
NHVLPYSQLFGPNALGTAELIRLALTTRIKPFTYVSTIGVGAGIEPGRFTEDDDIRVISPTRAVDTGYANGYGNSKWAGE
VLLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRMMLSLVTTGIAPKSFHPLDAKGHRQSAHYDGLPVEFVAES
ISALGAQAVDEAGTGFATYHVMNPHDDGIGLDEFVDWLVEAGYRIDRIDYYAAWLQRFETALRALPERTRQYSLLPLLHN
YQRPAHPINGAMAPTDRFRAAVQEAKLGPDKDIPHVTPAVIVKYATDLELLGLI
>Mature_1173_residues
STETREARLQQRIAHLFTTDPQFAAARPDPRISDAVDRDDTRLTAIVSAVMSGYADRPALGQRAAEFVTDPQTGRTTMEL
LPRFDTITYRELLDRVRALTNAWHADGVRPGDRVAILGFTGIDYTVVDLALIQLGAVAVPLQTSAAVEALRPIVAETEPM
LIATGVDHVDAAAELALTGHRPSRVVVFDHREQVDDERDAVRAATARLGDAVPVETLAEVLRRGAHLPAVAPHVFDEADP
LRLLIYTSGSAGAPKGAMYPESKVAGMWRASAKAAWNNDQTAIPSITLNFLPMSHVMGRGLLCGTLSTGGTAYFAARSDL
STLLEDLRLVRPTQLSFVPRIWDMLFQEFVGEVDRRVNDGADRPTAEADVLAVQRHELLGGRFVTAMTGSAPISLEMKTW
VETLLDMHLVEGYGSTEAGAVFVDGHIQRPPVLDYKLVDVPDLGYFSTDRPHPRGELLVRSTQLFPGYYKRPDVTAEVFD
DDGFYRTGDIVAEVGPDQVQYLDRRNNVLKLAQGEFVTISKLEAVFAGSALVRQIYVYGNSARSYLLAVVVPTDDAVARH
DPASLKTAISASLQQAAKTAGLQSYELPRDFLVETQPFTLENGLLTGIRKLARPKLKARYGDRLEALYVELVEGQAGELR
TLRRDGAKRPVAETVGRAAAALLGAAAADVRPDAHFTDLGGDSLSALTFGNLLQEIFGVDVPVGVIVSPAADLASIAAYI
EAEQASTGKRPTYASVHGRDAEQVHARDLTLDKFIDAETLSAATELPGPSGEVRTVLLTGATGFLGRYLALDWLERMALV
DGKVICLVRAKDDAAARKRLDDTFDSGDPKLLAHYRKLAADHLEVLAGDKGEADLGLPHPVWQRLADTVDLIVDPAALVN
HVLPYSQLFGPNALGTAELIRLALTTRIKPFTYVSTIGVGAGIEPGRFTEDDDIRVISPTRAVDTGYANGYGNSKWAGEV
LLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRMMLSLVTTGIAPKSFHPLDAKGHRQSAHYDGLPVEFVAESI
SALGAQAVDEAGTGFATYHVMNPHDDGIGLDEFVDWLVEAGYRIDRIDYYAAWLQRFETALRALPERTRQYSLLPLLHNY
QRPAHPINGAMAPTDRFRAAVQEAKLGPDKDIPHVTPAVIVKYATDLELLGLI

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI42794756, Length=585, Percent_Identity=27.008547008547, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI42794760, Length=585, Percent_Identity=27.008547008547, Blast_Score=202, Evalue=2e-51,
Organism=Homo sapiens, GI42794758, Length=585, Percent_Identity=27.008547008547, Blast_Score=202, Evalue=2e-51,
Organism=Homo sapiens, GI40807491, Length=598, Percent_Identity=26.7558528428094, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI57165410, Length=599, Percent_Identity=26.2103505843072, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI57165412, Length=602, Percent_Identity=26.4119601328904, Blast_Score=191, Evalue=4e-48,
Organism=Homo sapiens, GI42794754, Length=605, Percent_Identity=25.9504132231405, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI42794752, Length=605, Percent_Identity=25.9504132231405, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI4758332, Length=655, Percent_Identity=23.6641221374046, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI12669909, Length=647, Percent_Identity=23.8021638330757, Blast_Score=169, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17556552, Length=599, Percent_Identity=27.7128547579299, Blast_Score=209, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI17510401, Length=595, Percent_Identity=28.5714285714286, Blast_Score=205, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17564090, Length=478, Percent_Identity=29.0794979079498, Blast_Score=180, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17541856, Length=609, Percent_Identity=23.6453201970443, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193204819, Length=644, Percent_Identity=24.223602484472, Blast_Score=143, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17553312, Length=642, Percent_Identity=24.7663551401869, Blast_Score=139, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI25147511, Length=637, Percent_Identity=22.6059654631083, Blast_Score=137, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320852, Length=586, Percent_Identity=25.4266211604096, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323903, Length=616, Percent_Identity=25.3246753246753, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322182, Length=618, Percent_Identity=23.9482200647249, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319591, Length=736, Percent_Identity=24.4565217391304, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324893, Length=453, Percent_Identity=24.9448123620309, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366413, Length=617, Percent_Identity=28.2009724473258, Blast_Score=226, Evalue=7e-59,
Organism=Drosophila melanogaster, GI24666501, Length=617, Percent_Identity=28.2009724473258, Blast_Score=226, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24666497, Length=617, Percent_Identity=28.2009724473258, Blast_Score=226, Evalue=1e-58,
Organism=Drosophila melanogaster, GI62471681, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI62471687, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24586634, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI22026970, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI62471679, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI62471683, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI62471685, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24586636, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI62471689, Length=484, Percent_Identity=26.4462809917355, Blast_Score=154, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 127632; Mature: 127501

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50075 ACP_DOMAIN ; PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTETREARLQQRIAHLFTTDPQFAAARPDPRISDAVDRDDTRLTAIVSAVMSGYADRPA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCH
LGQRAAEFVTDPQTGRTTMELLPRFDTITYRELLDRVRALTNAWHADGVRPGDRVAILGF
HHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
TGIDYTVVDLALIQLGAVAVPLQTSAAVEALRPIVAETEPMLIATGVDHVDAAAELALTG
CCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHEEEC
HRPSRVVVFDHREQVDDERDAVRAATARLGDAVPVETLAEVLRRGAHLPAVAPHVFDEAD
CCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCC
PLRLLIYTSGSAGAPKGAMYPESKVAGMWRASAKAAWNNDQTAIPSITLNFLPMSHVMGR
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHCC
GLLCGTLSTGGTAYFAARSDLSTLLEDLRLVRPTQLSFVPRIWDMLFQEFVGEVDRRVND
CEEEEECCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GADRPTAEADVLAVQRHELLGGRFVTAMTGSAPISLEMKTWVETLLDMHLVEGYGSTEAG
CCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCC
AVFVDGHIQRPPVLDYKLVDVPDLGYFSTDRPHPRGELLVRSTQLFPGYYKRPDVTAEVF
EEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCEEEEE
DDDGFYRTGDIVAEVGPDQVQYLDRRNNVLKLAQGEFVTISKLEAVFAGSALVRQIYVYG
CCCCCEECCCEEECCCCHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHHHHHHEEHEEC
NSARSYLLAVVVPTDDAVARHDPASLKTAISASLQQAAKTAGLQSYELPRDFLVETQPFT
CCCCEEEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCE
LENGLLTGIRKLARPKLKARYGDRLEALYVELVEGQAGELRTLRRDGAKRPVAETVGRAA
ECCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHH
AALLGAAAADVRPDAHFTDLGGDSLSALTFGNLLQEIFGVDVPVGVIVSPAADLASIAAY
HHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHH
IEAEQASTGKRPTYASVHGRDAEQVHARDLTLDKFIDAETLSAATELPGPSGEVRTVLLT
HHHHHHCCCCCCCEEECCCCCHHHHHHHCCCHHHHCCHHHHHHHHCCCCCCCCEEEEEEE
GATGFLGRYLALDWLERMALVDGKVICLVRAKDDAAARKRLDDTFDSGDPKLLAHYRKLA
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
ADHLEVLAGDKGEADLGLPHPVWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAEL
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCCCCHHHH
IRLALTTRIKPFTYVSTIGVGAGIEPGRFTEDDDIRVISPTRAVDTGYANGYGNSKWAGE
HHHHHHHCCCCEEEHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHH
VLLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRMMLSLVTTGIAPKSFHPLDA
HHHHHHHHHCCCCHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
KGHRQSAHYDGLPVEFVAESISALGAQAVDEAGTGFATYHVMNPHDDGIGLDEFVDWLVE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHH
AGYRIDRIDYYAAWLQRFETALRALPERTRQYSLLPLLHNYQRPAHPINGAMAPTDRFRA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHCCCCCCCCCCCCCCCHHHHHH
AVQEAKLGPDKDIPHVTPAVIVKYATDLELLGLI
HHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
STETREARLQQRIAHLFTTDPQFAAARPDPRISDAVDRDDTRLTAIVSAVMSGYADRPA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCH
LGQRAAEFVTDPQTGRTTMELLPRFDTITYRELLDRVRALTNAWHADGVRPGDRVAILGF
HHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
TGIDYTVVDLALIQLGAVAVPLQTSAAVEALRPIVAETEPMLIATGVDHVDAAAELALTG
CCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHEEEC
HRPSRVVVFDHREQVDDERDAVRAATARLGDAVPVETLAEVLRRGAHLPAVAPHVFDEAD
CCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCC
PLRLLIYTSGSAGAPKGAMYPESKVAGMWRASAKAAWNNDQTAIPSITLNFLPMSHVMGR
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHCC
GLLCGTLSTGGTAYFAARSDLSTLLEDLRLVRPTQLSFVPRIWDMLFQEFVGEVDRRVND
CEEEEECCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GADRPTAEADVLAVQRHELLGGRFVTAMTGSAPISLEMKTWVETLLDMHLVEGYGSTEAG
CCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCC
AVFVDGHIQRPPVLDYKLVDVPDLGYFSTDRPHPRGELLVRSTQLFPGYYKRPDVTAEVF
EEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCEEEEE
DDDGFYRTGDIVAEVGPDQVQYLDRRNNVLKLAQGEFVTISKLEAVFAGSALVRQIYVYG
CCCCCEECCCEEECCCCHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHHHHHHEEHEEC
NSARSYLLAVVVPTDDAVARHDPASLKTAISASLQQAAKTAGLQSYELPRDFLVETQPFT
CCCCEEEEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCE
LENGLLTGIRKLARPKLKARYGDRLEALYVELVEGQAGELRTLRRDGAKRPVAETVGRAA
ECCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHH
AALLGAAAADVRPDAHFTDLGGDSLSALTFGNLLQEIFGVDVPVGVIVSPAADLASIAAY
HHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHH
IEAEQASTGKRPTYASVHGRDAEQVHARDLTLDKFIDAETLSAATELPGPSGEVRTVLLT
HHHHHHCCCCCCCEEECCCCCHHHHHHHCCCHHHHCCHHHHHHHHCCCCCCCCEEEEEEE
GATGFLGRYLALDWLERMALVDGKVICLVRAKDDAAARKRLDDTFDSGDPKLLAHYRKLA
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
ADHLEVLAGDKGEADLGLPHPVWQRLADTVDLIVDPAALVNHVLPYSQLFGPNALGTAEL
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCCCCHHHH
IRLALTTRIKPFTYVSTIGVGAGIEPGRFTEDDDIRVISPTRAVDTGYANGYGNSKWAGE
HHHHHHHCCCCEEEHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHH
VLLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRMMLSLVTTGIAPKSFHPLDA
HHHHHHHHHCCCCHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
KGHRQSAHYDGLPVEFVAESISALGAQAVDEAGTGFATYHVMNPHDDGIGLDEFVDWLVE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHH
AGYRIDRIDYYAAWLQRFETALRALPERTRQYSLLPLLHNYQRPAHPINGAMAPTDRFRA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHCCCCCCCCCCCCCCCHHHHHH
AVQEAKLGPDKDIPHVTPAVIVKYATDLELLGLI
HHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA