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The map label for this gene is desA3 [H]

Identifier: 119868351

GI number: 119868351

Start: 2421005

End: 2422399

Strand: Reverse

Name: desA3 [H]

Synonym: Mkms_2315

Alternate gene names: 119868351

Gene position: 2422399-2421005 (Counterclockwise)

Preceding gene: 119868352

Following gene: 119868346

Centisome position: 42.22

GC content: 63.23

Gene sequence:

>1395_bases
GTGACCACCACTGTCGAGAGCCCCCTGGCCCGTCTCACCGAGCAGGAGTTGGAAAAGCTCGCCAAGGAACTCGACGCGAT
ACACGACGAGATCTTCAGTGAACTCGGCGACCGGGACCGCAACTACATCAAGGCGGTCATCTCGGTCCAGCGCCAGATCG
TGGTCGCCGGTCGGGTACTGCTGCTCGCCTCACGGTCGCGGACTGCCCTGGTGGCGGGCACGGCCTGTCTGGGTATGGCC
AAGATCCTGGAGAACATGGAACTCGGCCACAACATCCTGCACGGCCAATGGGACTGGATGAACGATCCTGACATCCACTC
ATCGGTCTGGGACTGGGACACCGCCTCGACCGCGAAGGCCTGGAAGCACTCGCACAACTACATTCACCACACCTATACCA
ACATCCGTGGCAAGGACAAGGATCTCGGCTACGAGATCATGCGGATCGATCCCAACCAGAAGTGGCGCCCCGCCAATCTC
GGCCAACCGCTCTACAACTTCCTGCTCACGGTCCTGTTCGAATGGGGCGTGGCGTTGCACGACACCGACGTCGAGGCACT
GTGGCGCGGCCAGAAGACGATGGCCGATCTCAAGGAGGATTTCCGGGGCATCGCCGGCAAAGCGCGCCTGCAGATCATCA
AGGACTACGTCGGCTGGCCGTTGATCAGCGCCGGCGCCTTCGCGCTCGCACAGTTGGCTCTGCGCGGGCGAATCGACCAG
CCTGCCGAGTCGCGGGTGGCCAGGCGACTTCGCCAAATATCGACCAAGGGTCGCATCGGCGCAACGGCCACTGTGCTCGA
CCGTCTGCTACCCGGCGTCGAGAGCACATTCCTGCGCACTTTGGCGGCCGACGCTCTGGCCAACCTCATTCGCAACGTGT
GGGCGCACGCCATCATCTTCTGCGGCCACTTTCCCGACCAGACATATACATTCAGTGAAGAGGAAGTGGAGAACGAGTCG
CGCGGTGGGTGGTACGTCCGCCAATTGATCGGCGCAGCCAACATCGAGGGCAGCCCGCTCTTCCACGTGATCAGCGGAAA
CCTCGGTTACCAGGTCGAACACCACCTCTATCCCGACATGCCGAGCAGCCGGTACTCCGAGATCGCGCCCAGAATCAAAG
ACATCTGCGAGCGGTACGAATTACCGTACAACTCCGGACGATTCGGCAAACAATGGTTCTCGGTGCACCGCACCATCTTC
CGTCTGGCCTTTCCGGGCGGGAAGCCGCGACCCAAGCCCGGGCCCTACCGCAGCCAGGATCGGAACCCGACCCGGGAAGC
CCCGAGCGAAGCCGTACGATTCCGCGACCGCCTTCCCGCCGAACATCCGGATGCCGGTCCCGAGCACGCGTCTACCGGCG
TCGCGGTGCAGCCGCCGCCGCGCGGCAACGACTGA

Upstream 100 bases:

>100_bases
CCTGCGGTCTGGAGAAGTCACCGAACCGACCGGGCAGGACGTCCGGATCTGCATCCACGCCGCTGAAGGCGACGTCGAAT
TCGAACTCTGAGGAGCCACT

Downstream 100 bases:

>100_bases
CGCTCCGCTGCGTCCTCAGTCGAACAGCCCGGTCTGGCCCAGTCCGGTGATGCCGCTGGGTGGGGTCAGGCCGAGATGCG
TCCAGGCCGACGCGGTGGCC

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(9)-desaturase; Stearoyl-CoA desaturase [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTTTVESPLARLTEQELEKLAKELDAIHDEIFSELGDRDRNYIKAVISVQRQIVVAGRVLLLASRSRTALVAGTACLGMA
KILENMELGHNILHGQWDWMNDPDIHSSVWDWDTASTAKAWKHSHNYIHHTYTNIRGKDKDLGYEIMRIDPNQKWRPANL
GQPLYNFLLTVLFEWGVALHDTDVEALWRGQKTMADLKEDFRGIAGKARLQIIKDYVGWPLISAGAFALAQLALRGRIDQ
PAESRVARRLRQISTKGRIGATATVLDRLLPGVESTFLRTLAADALANLIRNVWAHAIIFCGHFPDQTYTFSEEEVENES
RGGWYVRQLIGAANIEGSPLFHVISGNLGYQVEHHLYPDMPSSRYSEIAPRIKDICERYELPYNSGRFGKQWFSVHRTIF
RLAFPGGKPRPKPGPYRSQDRNPTREAPSEAVRFRDRLPAEHPDAGPEHASTGVAVQPPPRGND

Sequences:

>Translated_464_residues
MTTTVESPLARLTEQELEKLAKELDAIHDEIFSELGDRDRNYIKAVISVQRQIVVAGRVLLLASRSRTALVAGTACLGMA
KILENMELGHNILHGQWDWMNDPDIHSSVWDWDTASTAKAWKHSHNYIHHTYTNIRGKDKDLGYEIMRIDPNQKWRPANL
GQPLYNFLLTVLFEWGVALHDTDVEALWRGQKTMADLKEDFRGIAGKARLQIIKDYVGWPLISAGAFALAQLALRGRIDQ
PAESRVARRLRQISTKGRIGATATVLDRLLPGVESTFLRTLAADALANLIRNVWAHAIIFCGHFPDQTYTFSEEEVENES
RGGWYVRQLIGAANIEGSPLFHVISGNLGYQVEHHLYPDMPSSRYSEIAPRIKDICERYELPYNSGRFGKQWFSVHRTIF
RLAFPGGKPRPKPGPYRSQDRNPTREAPSEAVRFRDRLPAEHPDAGPEHASTGVAVQPPPRGND
>Mature_463_residues
TTTVESPLARLTEQELEKLAKELDAIHDEIFSELGDRDRNYIKAVISVQRQIVVAGRVLLLASRSRTALVAGTACLGMAK
ILENMELGHNILHGQWDWMNDPDIHSSVWDWDTASTAKAWKHSHNYIHHTYTNIRGKDKDLGYEIMRIDPNQKWRPANLG
QPLYNFLLTVLFEWGVALHDTDVEALWRGQKTMADLKEDFRGIAGKARLQIIKDYVGWPLISAGAFALAQLALRGRIDQP
AESRVARRLRQISTKGRIGATATVLDRLLPGVESTFLRTLAADALANLIRNVWAHAIIFCGHFPDQTYTFSEEEVENESR
GGWYVRQLIGAANIEGSPLFHVISGNLGYQVEHHLYPDMPSSRYSEIAPRIKDICERYELPYNSGRFGKQWFSVHRTIFR
LAFPGGKPRPKPGPYRSQDRNPTREAPSEAVRFRDRLPAEHPDAGPEHASTGVAVQPPPRGND

Specific function: Desaturates stearoyl-CoA to form oleoyl-CoA [H]

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Probable). Note=Has been shown to be membrane-associated but no reliable trans-membrane regions are predicted by bioinformatics tools [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: NA

Molecular weight: Translated: 52391; Mature: 52260

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTVESPLARLTEQELEKLAKELDAIHDEIFSELGDRDRNYIKAVISVQRQIVVAGRVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LLASRSRTALVAGTACLGMAKILENMELGHNILHGQWDWMNDPDIHSSVWDWDTASTAKA
EEECCCCCEEEHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
WKHSHNYIHHTYTNIRGKDKDLGYEIMRIDPNQKWRPANLGQPLYNFLLTVLFEWGVALH
HHHCCCCEEEHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
DTDVEALWRGQKTMADLKEDFRGIAGKARLQIIKDYVGWPLISAGAFALAQLALRGRIDQ
CCCHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
PAESRVARRLRQISTKGRIGATATVLDRLLPGVESTFLRTLAADALANLIRNVWAHAIIF
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGHFPDQTYTFSEEEVENESRGGWYVRQLIGAANIEGSPLFHVISGNLGYQVEHHLYPDM
CCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCCCC
PSSRYSEIAPRIKDICERYELPYNSGRFGKQWFSVHRTIFRLAFPGGKPRPKPGPYRSQD
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
RNPTREAPSEAVRFRDRLPAEHPDAGPEHASTGVAVQPPPRGND
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure 
TTTVESPLARLTEQELEKLAKELDAIHDEIFSELGDRDRNYIKAVISVQRQIVVAGRVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LLASRSRTALVAGTACLGMAKILENMELGHNILHGQWDWMNDPDIHSSVWDWDTASTAKA
EEECCCCCEEEHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
WKHSHNYIHHTYTNIRGKDKDLGYEIMRIDPNQKWRPANLGQPLYNFLLTVLFEWGVALH
HHHCCCCEEEHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
DTDVEALWRGQKTMADLKEDFRGIAGKARLQIIKDYVGWPLISAGAFALAQLALRGRIDQ
CCCHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
PAESRVARRLRQISTKGRIGATATVLDRLLPGVESTFLRTLAADALANLIRNVWAHAIIF
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGHFPDQTYTFSEEEVENESRGGWYVRQLIGAANIEGSPLFHVISGNLGYQVEHHLYPDM
CCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCCCC
PSSRYSEIAPRIKDICERYELPYNSGRFGKQWFSVHRTIFRLAFPGGKPRPKPGPYRSQD
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
RNPTREAPSEAVRFRDRLPAEHPDAGPEHASTGVAVQPPPRGND
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]