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The map label for this gene is msrB [H]

Identifier: 119868298

GI number: 119868298

Start: 2375625

End: 2376035

Strand: Reverse

Name: msrB [H]

Synonym: Mkms_2262

Alternate gene names: 119868298

Gene position: 2376035-2375625 (Counterclockwise)

Preceding gene: 119868299

Following gene: 119868293

Centisome position: 41.41

GC content: 65.69

Gene sequence:

>411_bases
ATGAGTGCTCCGAAGGTGCAACTGACCGACGACGAGTGGCGTCAGAAGCTCAGCCCCGAGGAATTCGCGGTGCTGCGGCG
GGCGGGCACCGAACGTCCGTTCACCGGTGAGTACACCGACACCGAGACCAAGGGCGTCTACCAGTGCCGGGCGTGCGGCG
CGGAACTGTTCCGCAGCTCCGAGAAGTTCGAATCCCATTGCGGCTGGCCGTCGTTCTTCGACCCGGCCGATTCCGACGCG
GTGATCCTGCGGCCCGACGATTCGCTGGGGATGCGACGGGTCGAGGTGGTGTGCGCGAACTGCCACAGCCATCTGGGCCA
CGTGTTCGAAGGCGAGGGCTATCCGACGCCCACCGATCAGCGGTACTGCATCAATTCCATCTCACTGCGGCTGGTGCCGG
CGGGCGGATAG

Upstream 100 bases:

>100_bases
CCGCCTCGACCGGGGCATCGACCCGCTGTGGCTGACCGACCCCGCCGAGGACTCCGCGCAGGTCAAGCGGGCCGCGCCGA
CGGCGTAGTAACTTGGGGTC

Downstream 100 bases:

>100_bases
TCTCCGCCCGCAGCAGCGCCGTGACCCCGGGCGCGCTCAGTGGCGGGCTGTAGTGGAAACCCTGCGCCACATCGCACCCG
TAATCGCGGAGGCGTTCGGC

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSAPKVQLTDDEWRQKLSPEEFAVLRRAGTERPFTGEYTDTETKGVYQCRACGAELFRSSEKFESHCGWPSFFDPADSDA
VILRPDDSLGMRRVEVVCANCHSHLGHVFEGEGYPTPTDQRYCINSISLRLVPAGG

Sequences:

>Translated_136_residues
MSAPKVQLTDDEWRQKLSPEEFAVLRRAGTERPFTGEYTDTETKGVYQCRACGAELFRSSEKFESHCGWPSFFDPADSDA
VILRPDDSLGMRRVEVVCANCHSHLGHVFEGEGYPTPTDQRYCINSISLRLVPAGG
>Mature_135_residues
SAPKVQLTDDEWRQKLSPEEFAVLRRAGTERPFTGEYTDTETKGVYQCRACGAELFRSSEKFESHCGWPSFFDPADSDAV
ILRPDDSLGMRRVEVVCANCHSHLGHVFEGEGYPTPTDQRYCINSISLRLVPAGG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=130, Percent_Identity=46.1538461538462, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI301336162, Length=130, Percent_Identity=46.1538461538462, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI73089054, Length=130, Percent_Identity=46.1538461538462, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI37620216, Length=130, Percent_Identity=46.1538461538462, Blast_Score=127, Evalue=2e-30,
Organism=Homo sapiens, GI117606353, Length=136, Percent_Identity=42.6470588235294, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI7706511, Length=103, Percent_Identity=37.8640776699029, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=45.9016393442623, Blast_Score=119, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=119, Percent_Identity=47.8991596638655, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17553450, Length=119, Percent_Identity=47.8991596638655, Blast_Score=109, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319816, Length=127, Percent_Identity=45.6692913385827, Blast_Score=122, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45553335, Length=131, Percent_Identity=49.618320610687, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356369, Length=131, Percent_Identity=49.618320610687, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24645799, Length=131, Percent_Identity=49.618320610687, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI221378664, Length=132, Percent_Identity=46.2121212121212, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI221378662, Length=139, Percent_Identity=44.6043165467626, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24645804, Length=142, Percent_Identity=45.0704225352113, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24645801, Length=142, Percent_Identity=45.0704225352113, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15218; Mature: 15087

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPKVQLTDDEWRQKLSPEEFAVLRRAGTERPFTGEYTDTETKGVYQCRACGAELFRSS
CCCCCCEECCHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCH
EKFESHCGWPSFFDPADSDAVILRPDDSLGMRRVEVVCANCHSHLGHVFEGEGYPTPTDQ
HHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
RYCINSISLRLVPAGG
CEEECCEEEEEEECCC
>Mature Secondary Structure 
SAPKVQLTDDEWRQKLSPEEFAVLRRAGTERPFTGEYTDTETKGVYQCRACGAELFRSS
CCCCCEECCHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCH
EKFESHCGWPSFFDPADSDAVILRPDDSLGMRRVEVVCANCHSHLGHVFEGEGYPTPTDQ
HHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
RYCINSISLRLVPAGG
CEEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA