Click here to switch to the map view.

The map label for this gene is gluD [H]

Identifier: 119868235

GI number: 119868235

Start: 2313007

End: 2313885

Strand: Reverse

Name: gluD [H]

Synonym: Mkms_2199

Alternate gene names: 119868235

Gene position: 2313885-2313007 (Counterclockwise)

Preceding gene: 119868236

Following gene: 119868234

Centisome position: 40.33

GC content: 67.35

Gene sequence:

>879_bases
ATGAGCGGCACCGTCCTGTTCGACGCGCCCGGGCCGCGCGCCCGGCGACGCAACATCGTCATCACGCTCATCACGTTGGC
GATCACCGCGCTGATCGTCTGGGTTGTGTACTCGCGGCTCGACGCGAAAGGTCAGCTCACCGCGGCGAAGTGGGAGCCGT
TCCTGACGCCGAACCTGTGGACCACCTACGTGCTGCCCGGCGTGCAGGGCACGTTGACCGCGGCGGCGGTGTCGATCGTG
CTGGCGCTGATCCTGGGATTCGGGCTCGGAGTCGGCAGGCTGTCGGTGATCACGCCGATCCGCTGGGTGTGCGCGGTGAT
CGTGGAGTTCTTCCGCGCGGTCCCGGTGCTGATCATGATGATCTTCGCGTACTTCCTGTACGCGTTCTACGACGTCTTCC
CCTCCAAACACCTTGCGCTGGCCGGCGTCATCACCGGCCTCACGCTCTACAACGGCGCGGTGATCGCCGAGATCGTCCGG
GCCGGGGTGAAGGCGTTGCCGCGCGGTCAGGCCGAGGCCGCCTCGGCGCTGGGCCTGCGCTGGGGGCAGACCCAGCGCTC
GATCCTGCTGCCGCAGGCCGTCACGTCGATGTTGCCGGTCCTGGTGTCCCAACTCGTGGTGGTCCTGAAGGACACCGCGA
TCGGCTACCAGATCACGTTCGTCGAGATGGTGCGTCAGGGCACCGTGGTCGGCTCGTCCTACGGCAATTACATCCCCGCC
CTCATCGTCATCGCCGTGTTGATGATCAGTGTGAACTTCGCGTTGTCCGCCCTGGCGACCAAACTCGAACGCCGGATGCG
GCGGTCGCGGCGCGGACCGGCGCCGCTGGACACCGAGGCCATCGAGCAGGAAGGCGCGCCGGGCGCGAAGGTGGTGTAG

Upstream 100 bases:

>100_bases
CGGATGGCTCGGGAAACGTCTGGCGGTGGCCCGGTGATGAGCGCTTGCGCGAAGAACGGACGGAACCGATGAGCGCTTGC
GCGAAGAACGGACGGAACCG

Downstream 100 bases:

>100_bases
CGACCCCGGCCGCGACAGACTGATCGGGTGATCGAGACCGTTACGGCGCTGGACATCCTTCCCGAGTCGACGTTGCGCAG
CGCCGTCGACGTCATGGTCC

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSGTVLFDAPGPRARRRNIVITLITLAITALIVWVVYSRLDAKGQLTAAKWEPFLTPNLWTTYVLPGVQGTLTAAAVSIV
LALILGFGLGVGRLSVITPIRWVCAVIVEFFRAVPVLIMMIFAYFLYAFYDVFPSKHLALAGVITGLTLYNGAVIAEIVR
AGVKALPRGQAEAASALGLRWGQTQRSILLPQAVTSMLPVLVSQLVVVLKDTAIGYQITFVEMVRQGTVVGSSYGNYIPA
LIVIAVLMISVNFALSALATKLERRMRRSRRGPAPLDTEAIEQEGAPGAKVV

Sequences:

>Translated_292_residues
MSGTVLFDAPGPRARRRNIVITLITLAITALIVWVVYSRLDAKGQLTAAKWEPFLTPNLWTTYVLPGVQGTLTAAAVSIV
LALILGFGLGVGRLSVITPIRWVCAVIVEFFRAVPVLIMMIFAYFLYAFYDVFPSKHLALAGVITGLTLYNGAVIAEIVR
AGVKALPRGQAEAASALGLRWGQTQRSILLPQAVTSMLPVLVSQLVVVLKDTAIGYQITFVEMVRQGTVVGSSYGNYIPA
LIVIAVLMISVNFALSALATKLERRMRRSRRGPAPLDTEAIEQEGAPGAKVV
>Mature_291_residues
SGTVLFDAPGPRARRRNIVITLITLAITALIVWVVYSRLDAKGQLTAAKWEPFLTPNLWTTYVLPGVQGTLTAAAVSIVL
ALILGFGLGVGRLSVITPIRWVCAVIVEFFRAVPVLIMMIFAYFLYAFYDVFPSKHLALAGVITGLTLYNGAVIAEIVRA
GVKALPRGQAEAASALGLRWGQTQRSILLPQAVTSMLPVLVSQLVVVLKDTAIGYQITFVEMVRQGTVVGSSYGNYIPAL
IVIAVLMISVNFALSALATKLERRMRRSRRGPAPLDTEAIEQEGAPGAKVV

Specific function: Part of the binding-protein-dependent transport system for glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=208, Percent_Identity=28.3653846153846, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788226, Length=215, Percent_Identity=29.7674418604651, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=30.4347826086957, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787030, Length=206, Percent_Identity=30.5825242718447, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786874, Length=220, Percent_Identity=26.8181818181818, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788645, Length=228, Percent_Identity=25.4385964912281, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994930, Length=129, Percent_Identity=34.1085271317829, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31464; Mature: 31333

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTVLFDAPGPRARRRNIVITLITLAITALIVWVVYSRLDAKGQLTAAKWEPFLTPNLW
CCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCCCCCCCH
TTYVLPGVQGTLTAAAVSIVLALILGFGLGVGRLSVITPIRWVCAVIVEFFRAVPVLIMM
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFAYFLYAFYDVFPSKHLALAGVITGLTLYNGAVIAEIVRAGVKALPRGQAEAASALGLR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
WGQTQRSILLPQAVTSMLPVLVSQLVVVLKDTAIGYQITFVEMVRQGTVVGSSYGNYIPA
CCCCHHHEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEECCCCCCHHHH
LIVIAVLMISVNFALSALATKLERRMRRSRRGPAPLDTEAIEQEGAPGAKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SGTVLFDAPGPRARRRNIVITLITLAITALIVWVVYSRLDAKGQLTAAKWEPFLTPNLW
CCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCCCCCCCH
TTYVLPGVQGTLTAAAVSIVLALILGFGLGVGRLSVITPIRWVCAVIVEFFRAVPVLIMM
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFAYFLYAFYDVFPSKHLALAGVITGLTLYNGAVIAEIVRAGVKALPRGQAEAASALGLR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
WGQTQRSILLPQAVTSMLPVLVSQLVVVLKDTAIGYQITFVEMVRQGTVVGSSYGNYIPA
CCCCHHHEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEECCCCCCHHHH
LIVIAVLMISVNFALSALATKLERRMRRSRRGPAPLDTEAIEQEGAPGAKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7868586; 12948626 [H]