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The map label for this gene is hypE [H]

Identifier: 119868215

GI number: 119868215

Start: 2296078

End: 2297145

Strand: Reverse

Name: hypE [H]

Synonym: Mkms_2179

Alternate gene names: 119868215

Gene position: 2297145-2296078 (Counterclockwise)

Preceding gene: 119868216

Following gene: 119868214

Centisome position: 40.04

GC content: 69.76

Gene sequence:

>1068_bases
ATGCGTGAGACCCGCGCAGCGATCGACATGGAGAGCTGGGTGTGCCCGGCGCCGCTGCGGGATTCGCCGAACGTCGTGAT
GGGTCACGGCGGTGGCGGCGCGATGTCGGGTGAGCTGATCGAGCATCTGTTCCTGCCCGCGTTCGGTCCGGCCGCGGACG
CGGCGATGGGCGATTCGGCCGTCGTCGAAATCGGCGGGACCCGGCTGGCGTTCTCCACCGATTCGTTCGTCGTCAAGCCG
ATGGTGTTCCCGGGCGGCACGATCGGCGAGCTGGCGGTCAACGGCACGGTCAACGACCTCGCGATGGCCGGCGCGACGCC
GATGGTGCTGTCGACGGCGTTCATCCTCGAGGAAGGCACCTCACTCGACGATCTGGCGCGGGTCGCTCATGCGGTCGGCA
CCGCGGCCTTGGCCGCCGGCGTCAAACTCGTCACCGGCGACACCAAGGTCGTCGATTCCGGGCACGGCGACGGAATCTAT
GTGAACACCACCGGTATCGGGGTGATCGACCGGCGGGCCGACATCCGGCCACAGCGCGCCACCGAGGGCGACGCGGTCAT
CGTCAGCGGCGACATCGGCGTCCACGGGGTCGCCGTTATGAGCTGCCGCGAAGGTCTGGAGTTCGCGACCAGCATCGCCA
GCGACACCGCGCCCCTGCACGGTCTGGTGGCGGCGATGATCGAGACCGGCGCCGACATCCACGCACTTCGCGACCCCACC
CGCGGCGGGATGGCCGCCACTCTGAACGAGATCGCCAAGGCCGCCGAGGTGGGCATGGTGCTCGACGAACGATCGATTCC
GGTGCCACCGGAGGTGCGCGACGCCTGCGGCCTGCTCGGCCTCGATCCGATGTATGTGGCCAACGAGGGCAAGCTGGTGG
CGTTCGTGCCGGCCGCCGACGCCGATCGTGTGGTCGAGGCGATGCGGGCACACCCGCTGGGCGCCCACGCCGCCGTCATC
GGCACCTGCGTCTCCGACCACCCCGGGATGGTCGTCGCCCGCACCGCACTGGGTGGTACGCGGGTGGTCGACCTGCCGAT
CGGCGAACAGCTACCCCGGATCTGTTGA

Upstream 100 bases:

>100_bases
GGCACGGTGTGCACACCCCGCAATCCGTTGGGCGCCACGATGGTCTCCTCCGAGGGCGCCTGCGCGGCCTATTACCTCTA
CCGTCGCCTCGAGGTCAGCC

Downstream 100 bases:

>100_bases
CATGCTGCCGACGCGGCGCCGCGGCGACACGCTCTTCGCCCGGTACGCCTTCCCGCCGAACGAACTCGGATACTGCGGTC
CGCCGGGTAGCGCGACCGTC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MRETRAAIDMESWVCPAPLRDSPNVVMGHGGGGAMSGELIEHLFLPAFGPAADAAMGDSAVVEIGGTRLAFSTDSFVVKP
MVFPGGTIGELAVNGTVNDLAMAGATPMVLSTAFILEEGTSLDDLARVAHAVGTAALAAGVKLVTGDTKVVDSGHGDGIY
VNTTGIGVIDRRADIRPQRATEGDAVIVSGDIGVHGVAVMSCREGLEFATSIASDTAPLHGLVAAMIETGADIHALRDPT
RGGMAATLNEIAKAAEVGMVLDERSIPVPPEVRDACGLLGLDPMYVANEGKLVAFVPAADADRVVEAMRAHPLGAHAAVI
GTCVSDHPGMVVARTALGGTRVVDLPIGEQLPRIC

Sequences:

>Translated_355_residues
MRETRAAIDMESWVCPAPLRDSPNVVMGHGGGGAMSGELIEHLFLPAFGPAADAAMGDSAVVEIGGTRLAFSTDSFVVKP
MVFPGGTIGELAVNGTVNDLAMAGATPMVLSTAFILEEGTSLDDLARVAHAVGTAALAAGVKLVTGDTKVVDSGHGDGIY
VNTTGIGVIDRRADIRPQRATEGDAVIVSGDIGVHGVAVMSCREGLEFATSIASDTAPLHGLVAAMIETGADIHALRDPT
RGGMAATLNEIAKAAEVGMVLDERSIPVPPEVRDACGLLGLDPMYVANEGKLVAFVPAADADRVVEAMRAHPLGAHAAVI
GTCVSDHPGMVVARTALGGTRVVDLPIGEQLPRIC
>Mature_355_residues
MRETRAAIDMESWVCPAPLRDSPNVVMGHGGGGAMSGELIEHLFLPAFGPAADAAMGDSAVVEIGGTRLAFSTDSFVVKP
MVFPGGTIGELAVNGTVNDLAMAGATPMVLSTAFILEEGTSLDDLARVAHAVGTAALAAGVKLVTGDTKVVDSGHGDGIY
VNTTGIGVIDRRADIRPQRATEGDAVIVSGDIGVHGVAVMSCREGLEFATSIASDTAPLHGLVAAMIETGADIHALRDPT
RGGMAATLNEIAKAAEVGMVLDERSIPVPPEVRDACGLLGLDPMYVANEGKLVAFVPAADADRVVEAMRAHPLGAHAAVI
GTCVSDHPGMVVARTALGGTRVVDLPIGEQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=340, Percent_Identity=44.1176470588235, Blast_Score=249, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36236; Mature: 36236

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRETRAAIDMESWVCPAPLRDSPNVVMGHGGGGAMSGELIEHLFLPAFGPAADAAMGDSA
CCCHHHHCCHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCHHCCCCCE
VVEIGGTRLAFSTDSFVVKPMVFPGGTIGELAVNGTVNDLAMAGATPMVLSTAFILEEGT
EEEECCEEEEEECCCEEEEEEECCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHHCCCC
SLDDLARVAHAVGTAALAAGVKLVTGDTKVVDSGHGDGIYVNTTGIGVIDRRADIRPQRA
CHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCEEEEEECCCEEEECCCCCCCCCC
TEGDAVIVSGDIGVHGVAVMSCREGLEFATSIASDTAPLHGLVAAMIETGADIHALRDPT
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCC
RGGMAATLNEIAKAAEVGMVLDERSIPVPPEVRDACGLLGLDPMYVANEGKLVAFVPAAD
CCCHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHCCCCCCCCEEEECCCCEEEEECCCC
ADRVVEAMRAHPLGAHAAVIGTCVSDHPGMVVARTALGGTRVVDLPIGEQLPRIC
HHHHHHHHHCCCCCCHHHHEEEHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MRETRAAIDMESWVCPAPLRDSPNVVMGHGGGGAMSGELIEHLFLPAFGPAADAAMGDSA
CCCHHHHCCHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCHHCCCCCE
VVEIGGTRLAFSTDSFVVKPMVFPGGTIGELAVNGTVNDLAMAGATPMVLSTAFILEEGT
EEEECCEEEEEECCCEEEEEEECCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHHCCCC
SLDDLARVAHAVGTAALAAGVKLVTGDTKVVDSGHGDGIYVNTTGIGVIDRRADIRPQRA
CHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCEEEEEECCCEEEECCCCCCCCCC
TEGDAVIVSGDIGVHGVAVMSCREGLEFATSIASDTAPLHGLVAAMIETGADIHALRDPT
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCC
RGGMAATLNEIAKAAEVGMVLDERSIPVPPEVRDACGLLGLDPMYVANEGKLVAFVPAAD
CCCHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHCCCCCCCCEEEECCCCEEEEECCCC
ADRVVEAMRAHPLGAHAAVIGTCVSDHPGMVVARTALGGTRVVDLPIGEQLPRIC
HHHHHHHHHCCCCCCHHHHEEEHHCCCCCEEEEEEECCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8326860 [H]