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The map label for this gene is 119867660

Identifier: 119867660

GI number: 119867660

Start: 1730980

End: 1732086

Strand: Reverse

Name: 119867660

Synonym: Mkms_1615

Alternate gene names: NA

Gene position: 1732086-1730980 (Counterclockwise)

Preceding gene: 119867662

Following gene: 119867659

Centisome position: 30.19

GC content: 67.75

Gene sequence:

>1107_bases
ATGGAATCATTCGTCCACTTGCGAAAAGGCAAGACGCCGCGGCGACCGCACGCCGATCTCGACGGCCAGAAAGACGACGA
ACTGGGCCGGGGCGGCTTCACCGGGCGGACGGCCAACATGTATCGCCGCAACGACCCGACCGCGTTCCGCACCGTCGGGC
CGCTGCGCCCCATCGACGTGCTCGGCGACCAGCTCAAACCCGGTGACGCAACCGACGCCGACGGCGCACCGCTGCTGATG
TTCTCCAACGCCGACTGCCAGGTCCTGCTGTCGCGGCGCAGCCAGGAGATGCCGTATTTCGCCCGATACGTCGACGGCGA
TCTGCTGTCCTTCGTGCACACCGGGTCCGGTCTGCTCGAGACGGAGTTCGGCCCGTTGCGCTACCGCGCCGGCGACTGGG
TCTACATCCCGAAGGCGTGCACGTTCCGCCAGATCCCGGACACCGAATCCACGCTGCTGATGATCCAGGCCACCGACGAG
TTCCGGGTGCCGCCGGCTGGCCCGCTCGGCCGGCATTTCCCGTTCGACCCGTCGCAGGCCGAGATCCCCGAGCCGGCGCC
CATCGACGACGGCGTCGGCCCGCAGGTCGACGGCGAGTACGAGGTCCGACTGTTCCACGAGGGCGGCCCGACATCGCTGT
TCTACCAACACCATCCGCTCGACGTCGAGGGGTGGCGCGGCGACAACTTCGCATTCACGTTCAACATCGAGGACTACAAC
GTCGTCACCTCCGACAGCGTGCACCTGCCGGCCACCGCGCATCTGTTCATGCAGGCCACCGGCGTGTACGTGATGAACTT
CCTCCCCAAACCGGCCGAGGGGGTGCCCGGCACCGAACGCACCCCCTGGTACCACCGCAACGTCGACTACGACGAGATCG
CGTTCTTCCACGGCGGGACCCTGTACGGCATCCCCATGCCGCCGGGGTTGATCTCGCATGCGCCGCAGGGCGTCCACCAC
GGCGCGCCTGAGAAGGCGCGGGAGCGGGCGCGTCGCAAGTTCGACGAGTACCAACGGGTGGACTGGCAGGTCATCGCCGT
CGACACCCGCAGGCGGTTGATCCCGTCACCGGAGGTACTCGCCAACGACCTGGGGCAGCACTCGTGA

Upstream 100 bases:

>100_bases
ACGGGAGAGTTGGACGGGGCCTTGTGCCGACCCGGAGATAAAAGTAACGTCAGTTTTAGTTCTGCACCGCCGTCCCGACG
CACTGTCACTGGAGACATCG

Downstream 100 bases:

>100_bases
CGACGGCGGTCAAGTACGAGTACGACCGGATCCCGTATCTCGTTGCGTACCAGAACACTTCGGGTGTGCGCGATGTCTAC
GGCGGGGTGGCCGAACTGGT

Product: homogentisate 1,2-dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MESFVHLRKGKTPRRPHADLDGQKDDELGRGGFTGRTANMYRRNDPTAFRTVGPLRPIDVLGDQLKPGDATDADGAPLLM
FSNADCQVLLSRRSQEMPYFARYVDGDLLSFVHTGSGLLETEFGPLRYRAGDWVYIPKACTFRQIPDTESTLLMIQATDE
FRVPPAGPLGRHFPFDPSQAEIPEPAPIDDGVGPQVDGEYEVRLFHEGGPTSLFYQHHPLDVEGWRGDNFAFTFNIEDYN
VVTSDSVHLPATAHLFMQATGVYVMNFLPKPAEGVPGTERTPWYHRNVDYDEIAFFHGGTLYGIPMPPGLISHAPQGVHH
GAPEKARERARRKFDEYQRVDWQVIAVDTRRRLIPSPEVLANDLGQHS

Sequences:

>Translated_368_residues
MESFVHLRKGKTPRRPHADLDGQKDDELGRGGFTGRTANMYRRNDPTAFRTVGPLRPIDVLGDQLKPGDATDADGAPLLM
FSNADCQVLLSRRSQEMPYFARYVDGDLLSFVHTGSGLLETEFGPLRYRAGDWVYIPKACTFRQIPDTESTLLMIQATDE
FRVPPAGPLGRHFPFDPSQAEIPEPAPIDDGVGPQVDGEYEVRLFHEGGPTSLFYQHHPLDVEGWRGDNFAFTFNIEDYN
VVTSDSVHLPATAHLFMQATGVYVMNFLPKPAEGVPGTERTPWYHRNVDYDEIAFFHGGTLYGIPMPPGLISHAPQGVHH
GAPEKARERARRKFDEYQRVDWQVIAVDTRRRLIPSPEVLANDLGQHS
>Mature_368_residues
MESFVHLRKGKTPRRPHADLDGQKDDELGRGGFTGRTANMYRRNDPTAFRTVGPLRPIDVLGDQLKPGDATDADGAPLLM
FSNADCQVLLSRRSQEMPYFARYVDGDLLSFVHTGSGLLETEFGPLRYRAGDWVYIPKACTFRQIPDTESTLLMIQATDE
FRVPPAGPLGRHFPFDPSQAEIPEPAPIDDGVGPQVDGEYEVRLFHEGGPTSLFYQHHPLDVEGWRGDNFAFTFNIEDYN
VVTSDSVHLPATAHLFMQATGVYVMNFLPKPAEGVPGTERTPWYHRNVDYDEIAFFHGGTLYGIPMPPGLISHAPQGVHH
GAPEKARERARRKFDEYQRVDWQVIAVDTRRRLIPSPEVLANDLGQHS

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: NA

Molecular weight: Translated: 41279; Mature: 41279

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESFVHLRKGKTPRRPHADLDGQKDDELGRGGFTGRTANMYRRNDPTAFRTVGPLRPIDV
CCCCEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCCCCCHHH
LGDQLKPGDATDADGAPLLMFSNADCQVLLSRRSQEMPYFARYVDGDLLSFVHTGSGLLE
HCCCCCCCCCCCCCCCCEEEECCCCHHHHHHCCCCCCCHHHHHHCCHHHHHHHCCCCCEE
TEFGPLRYRAGDWVYIPKACTFRQIPDTESTLLMIQATDEFRVPPAGPLGRHFPFDPSQA
CCCCCEEEECCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
EIPEPAPIDDGVGPQVDGEYEVRLFHEGGPTSLFYQHHPLDVEGWRGDNFAFTFNIEDYN
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCE
VVTSDSVHLPATAHLFMQATGVYVMNFLPKPAEGVPGTERTPWYHRNVDYDEIAFFHGGT
EEECCCEECCHHHEEHHHHHCEEEEECCCCCCCCCCCCCCCCCEECCCCHHHEEEEECCE
LYGIPMPPGLISHAPQGVHHGAPEKARERARRKFDEYQRVDWQVIAVDTRRRLIPSPEVL
EEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
ANDLGQHS
HHHHCCCC
>Mature Secondary Structure
MESFVHLRKGKTPRRPHADLDGQKDDELGRGGFTGRTANMYRRNDPTAFRTVGPLRPIDV
CCCCEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCCCCCHHH
LGDQLKPGDATDADGAPLLMFSNADCQVLLSRRSQEMPYFARYVDGDLLSFVHTGSGLLE
HCCCCCCCCCCCCCCCCEEEECCCCHHHHHHCCCCCCCHHHHHHCCHHHHHHHCCCCCEE
TEFGPLRYRAGDWVYIPKACTFRQIPDTESTLLMIQATDEFRVPPAGPLGRHFPFDPSQA
CCCCCEEEECCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
EIPEPAPIDDGVGPQVDGEYEVRLFHEGGPTSLFYQHHPLDVEGWRGDNFAFTFNIEDYN
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCE
VVTSDSVHLPATAHLFMQATGVYVMNFLPKPAEGVPGTERTPWYHRNVDYDEIAFFHGGT
EEECCCEECCHHHEEHHHHHCEEEEECCCCCCCCCCCCCCCCCEECCCCHHHEEEEECCE
LYGIPMPPGLISHAPQGVHHGAPEKARERARRKFDEYQRVDWQVIAVDTRRRLIPSPEVL
EEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
ANDLGQHS
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]