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The map label for this gene is nhaA2 [H]

Identifier: 119867539

GI number: 119867539

Start: 1604146

End: 1604829

Strand: Reverse

Name: nhaA2 [H]

Synonym: Mkms_1491

Alternate gene names: 119867539

Gene position: 1604829-1604146 (Counterclockwise)

Preceding gene: 119867544

Following gene: 119867538

Centisome position: 27.97

GC content: 61.84

Gene sequence:

>684_bases
ATGAAAACGAAAGGCCTCAGCTCGATTCTGGCCAACACCCGCGTGCTCCTCACGATCTTCGTCATCGCGGTCGCCACCGT
CGCCACCGCGGTCTTTCTCTCCGTGCGCGACAGCGGCTCGGCGGCCGAGGTTGCACTCGACGGGTCGCTAGCCGGCCAAA
CAGTCCGAGACAACAGTCACCGGCTGAACTCGGTACCTGACAGCGATGTCTACTTCGTCGAGTTCCTCGACTTCGAATGC
GAAGGCTGCCGCGCGCTCTACCCGGTCGTCGAGCAGCTGCGCGCCGAGTACGGCGACCGGGTGAACTTCGTACTGCGCTA
CTTCCCGCTACGATCCCACTTCAACGCCGAACGCGCCGCCCGCGCTGTCGAAGCCGCAGCCCAACAAGGCCAACTCGAAG
CGATGTACAAGAAAATGTATGAGACACAAGCCCAGTGGGGTGAACAGCAGGTTCCGGCCGATGATGTGTTCCGCGGATTC
GCCCAACAACTTGGCCTCGACATGAGCACCTTTGACGCCACCTACAACGACCCCGCAACCCTGGAACGCATCCAGCTCGA
CATCAGCGACGGCACCGCACTCGGTGTCCAAGGCACCCCCACCTTCTTCATCAACGACGAACGCATCCAGCCCCGCAGCT
ACGAAGACCTCACCACAGCACTTGATCAGGCTCTCGCGCGCTGA

Upstream 100 bases:

>100_bases
GCACCGTGGCCCTGATCTGCTCCGCGTGGGGCAGGTCCAAACACAGCAGATCGCAGGTATCCAGCGGCTCACTCATATCC
ATATACTAAAGTACGTTGAT

Downstream 100 bases:

>100_bases
TGCCGCCGTCCGCACATGCGGATCGACGGCCGGTAACAGGCAATCGACAGTGCCCCACGAGCGTGGGCGCTTCGCTGATC
AGCAAGATCGAGAACGGCTG

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKTKGLSSILANTRVLLTIFVIAVATVATAVFLSVRDSGSAAEVALDGSLAGQTVRDNSHRLNSVPDSDVYFVEFLDFEC
EGCRALYPVVEQLRAEYGDRVNFVLRYFPLRSHFNAERAARAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPADDVFRGF
AQQLGLDMSTFDATYNDPATLERIQLDISDGTALGVQGTPTFFINDERIQPRSYEDLTTALDQALAR

Sequences:

>Translated_227_residues
MKTKGLSSILANTRVLLTIFVIAVATVATAVFLSVRDSGSAAEVALDGSLAGQTVRDNSHRLNSVPDSDVYFVEFLDFEC
EGCRALYPVVEQLRAEYGDRVNFVLRYFPLRSHFNAERAARAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPADDVFRGF
AQQLGLDMSTFDATYNDPATLERIQLDISDGTALGVQGTPTFFINDERIQPRSYEDLTTALDQALAR
>Mature_227_residues
MKTKGLSSILANTRVLLTIFVIAVATVATAVFLSVRDSGSAAEVALDGSLAGQTVRDNSHRLNSVPDSDVYFVEFLDFEC
EGCRALYPVVEQLRAEYGDRVNFVLRYFPLRSHFNAERAARAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPADDVFRGF
AQQLGLDMSTFDATYNDPATLERIQLDISDGTALGVQGTPTFFINDERIQPRSYEDLTTALDQALAR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 25150; Mature: 25150

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKGLSSILANTRVLLTIFVIAVATVATAVFLSVRDSGSAAEVALDGSLAGQTVRDNSH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
RLNSVPDSDVYFVEFLDFECEGCRALYPVVEQLRAEYGDRVNFVLRYFPLRSHFNAERAA
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHH
RAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPADDVFRGFAQQLGLDMSTFDATYNDPAT
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCC
LERIQLDISDGTALGVQGTPTFFINDERIQPRSYEDLTTALDQALAR
EEEEEEEECCCEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTKGLSSILANTRVLLTIFVIAVATVATAVFLSVRDSGSAAEVALDGSLAGQTVRDNSH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
RLNSVPDSDVYFVEFLDFECEGCRALYPVVEQLRAEYGDRVNFVLRYFPLRSHFNAERAA
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHH
RAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPADDVFRGFAQQLGLDMSTFDATYNDPAT
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCC
LERIQLDISDGTALGVQGTPTFFINDERIQPRSYEDLTTALDQALAR
EEEEEEEECCCEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA