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The map label for this gene is cpsA1 [H]

Identifier: 119867405

GI number: 119867405

Start: 1449260

End: 1450528

Strand: Direct

Name: cpsA1 [H]

Synonym: Mkms_1355

Alternate gene names: 119867405

Gene position: 1449260-1450528 (Clockwise)

Preceding gene: 119867404

Following gene: 119867406

Centisome position: 25.26

GC content: 69.58

Gene sequence:

>1269_bases
ATGACGAAGTCGGCGACCGCCGCGGAGGCCGTTCTCGCGCGGCTCGACGGAATCCGCGGCTGGCAGGAAGACTGCTACCG
CGACCTCCATCGGCACCCCGAGTTGTCGCATCACGAGGTCAGGACCGCGGGTGTGATCGCCGAACGCCTGGGCCACGACG
GCTATCGGGTGCACGACAAGATCGGCGGCACCGGCGTCGTCGGCGTACTGGAGAACGGATCCGGCCCCACGGTGCTGCTG
CGGGCGGACATGGACGCGTTACCGGTGCGGGAAGCCACCGGACTGGACTACGCCAGTACGGTGAGCAGCGCCGACGCCGA
CGGCCACGAGGTGCCGGTGATGCATGCCTGCGGGCACGACGTCCACGTCACCGCGCTGCTCGGGGCCGCCCAACTGCTCG
CCGAGGGGCGCGATCATTGGAACGGCACCCTGGTCGCGCTGTTCCAACCGGCCGAGGAGTCGGCCGACGGTGCGCGAGCC
ATGGTCCGCGACGGCCTGGCGTCGGTGCTGCCTGCGGTCGACGTCGCGCTCGGACAGCACGTGTTCCCCATTCCGGCCGG
CATCATCGGCACCCATTCCGGCCCCTTCCTGGCCAGCGCCGACAGTATGCGCATCACCGTCTACGGGCGTGGTGCGCACG
GCTCCATGCCGCAGTCGTCCGTCGACCCGGTGGTGCTGGCCGCCATGATCGTGATCCGGCTGCAGACGATCGTGTCCCGG
GAGGTGGCCCCCGTCGACTCCGTCGTGCTCACGGTGGGCAGCATCGAATCCGGCAACAAGAGCAACGTCATCCCCGATCG
GGCGGTGCTCCAGCTCAACATTCGTACCTACGGCGAGCAGACCCGCACGACCGTCCTCGACGCGATCCGCCGGATCGTGA
CGGCCGAGTGCATGGCATCGGGGTGCCCGCGCGAGCCCGAGTTCGAGATGTTCGGCCGGTTCCCGTTGACCGACAACGAC
CCCGGTGCGACCGCGCGGGTGCGTGAGGCGTTCACGGCGTTCTTCGGGGACCGGTGTATGGACATGCCGCAGGGTGCGGC
CAGTGAGGATTTCAGTGAGATCCCGGTCGCCCTCGGGGCGCCGTACACCTACTGGGGGGTGGGTGGCACCGATCCGGCGG
CGTTCCGGCAGGCCATGGAAAGCGGTCGCGTCGAGCAGGACATCCCGGTGAACCACTCACCGCACTATGCGCCCGTCATC
CAACCGACGCTCGATGCCGCGACCCAGGCCATGGTGGTCGCCGCGCTGGCCTGGCTGGCCGCGGCGTGA

Upstream 100 bases:

>100_bases
GCTCCACACCGAAACGCCGCGGCGCAATCGCCGCGGCGTTTCGGCGTCTGTGGGAGGAGGTACACCCGGACCATCCATCT
GCAACGAAGCAGGAGGCCCC

Downstream 100 bases:

>100_bases
CGCCGGTTGCTCTGTGGCAGTGAGGGTTTGACGAAACCGGCACCGGGTCGTGGCAGCGGTCTGTTAACGTCGCGGGGTGC
TTCGGGGATCAGGGGGGTTG

Product: amidohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MTKSATAAEAVLARLDGIRGWQEDCYRDLHRHPELSHHEVRTAGVIAERLGHDGYRVHDKIGGTGVVGVLENGSGPTVLL
RADMDALPVREATGLDYASTVSSADADGHEVPVMHACGHDVHVTALLGAAQLLAEGRDHWNGTLVALFQPAEESADGARA
MVRDGLASVLPAVDVALGQHVFPIPAGIIGTHSGPFLASADSMRITVYGRGAHGSMPQSSVDPVVLAAMIVIRLQTIVSR
EVAPVDSVVLTVGSIESGNKSNVIPDRAVLQLNIRTYGEQTRTTVLDAIRRIVTAECMASGCPREPEFEMFGRFPLTDND
PGATARVREAFTAFFGDRCMDMPQGAASEDFSEIPVALGAPYTYWGVGGTDPAAFRQAMESGRVEQDIPVNHSPHYAPVI
QPTLDAATQAMVVAALAWLAAA

Sequences:

>Translated_422_residues
MTKSATAAEAVLARLDGIRGWQEDCYRDLHRHPELSHHEVRTAGVIAERLGHDGYRVHDKIGGTGVVGVLENGSGPTVLL
RADMDALPVREATGLDYASTVSSADADGHEVPVMHACGHDVHVTALLGAAQLLAEGRDHWNGTLVALFQPAEESADGARA
MVRDGLASVLPAVDVALGQHVFPIPAGIIGTHSGPFLASADSMRITVYGRGAHGSMPQSSVDPVVLAAMIVIRLQTIVSR
EVAPVDSVVLTVGSIESGNKSNVIPDRAVLQLNIRTYGEQTRTTVLDAIRRIVTAECMASGCPREPEFEMFGRFPLTDND
PGATARVREAFTAFFGDRCMDMPQGAASEDFSEIPVALGAPYTYWGVGGTDPAAFRQAMESGRVEQDIPVNHSPHYAPVI
QPTLDAATQAMVVAALAWLAAA
>Mature_421_residues
TKSATAAEAVLARLDGIRGWQEDCYRDLHRHPELSHHEVRTAGVIAERLGHDGYRVHDKIGGTGVVGVLENGSGPTVLLR
ADMDALPVREATGLDYASTVSSADADGHEVPVMHACGHDVHVTALLGAAQLLAEGRDHWNGTLVALFQPAEESADGARAM
VRDGLASVLPAVDVALGQHVFPIPAGIIGTHSGPFLASADSMRITVYGRGAHGSMPQSSVDPVVLAAMIVIRLQTIVSRE
VAPVDSVVLTVGSIESGNKSNVIPDRAVLQLNIRTYGEQTRTTVLDAIRRIVTAECMASGCPREPEFEMFGRFPLTDNDP
GATARVREAFTAFFGDRCMDMPQGAASEDFSEIPVALGAPYTYWGVGGTDPAAFRQAMESGRVEQDIPVNHSPHYAPVIQ
PTLDAATQAMVVAALAWLAAA

Specific function: Can release basic, acidic, aromatic, and, to a lesser extent, aliphatic amino acids [H]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=314, Percent_Identity=27.0700636942675, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: NA

Molecular weight: Translated: 44718; Mature: 44587

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSATAAEAVLARLDGIRGWQEDCYRDLHRHPELSHHEVRTAGVIAERLGHDGYRVHDK
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECC
IGGTGVVGVLENGSGPTVLLRADMDALPVREATGLDYASTVSSADADGHEVPVMHACGHD
CCCCEEEEEEECCCCCEEEEEECCCCCCCHHHCCCCHHHHHCCCCCCCCCCCEEECCCCC
VHVTALLGAAQLLAEGRDHWNGTLVALFQPAEESADGARAMVRDGLASVLPAVDVALGQH
EEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
VFPIPAGIIGTHSGPFLASADSMRITVYGRGAHGSMPQSSVDPVVLAAMIVIRLQTIVSR
CCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EVAPVDSVVLTVGSIESGNKSNVIPDRAVLQLNIRTYGEQTRTTVLDAIRRIVTAECMAS
CCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHC
GCPREPEFEMFGRFPLTDNDPGATARVREAFTAFFGDRCMDMPQGAASEDFSEIPVALGA
CCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHCC
PYTYWGVGGTDPAAFRQAMESGRVEQDIPVNHSPHYAPVIQPTLDAATQAMVVAALAWLA
CEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AA
CC
>Mature Secondary Structure 
TKSATAAEAVLARLDGIRGWQEDCYRDLHRHPELSHHEVRTAGVIAERLGHDGYRVHDK
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECC
IGGTGVVGVLENGSGPTVLLRADMDALPVREATGLDYASTVSSADADGHEVPVMHACGHD
CCCCEEEEEEECCCCCEEEEEECCCCCCCHHHCCCCHHHHHCCCCCCCCCCCEEECCCCC
VHVTALLGAAQLLAEGRDHWNGTLVALFQPAEESADGARAMVRDGLASVLPAVDVALGQH
EEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
VFPIPAGIIGTHSGPFLASADSMRITVYGRGAHGSMPQSSVDPVVLAAMIVIRLQTIVSR
CCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EVAPVDSVVLTVGSIESGNKSNVIPDRAVLQLNIRTYGEQTRTTVLDAIRRIVTAECMAS
CCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHC
GCPREPEFEMFGRFPLTDNDPGATARVREAFTAFFGDRCMDMPQGAASEDFSEIPVALGA
CCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHCC
PYTYWGVGGTDPAAFRQAMESGRVEQDIPVNHSPHYAPVIQPTLDAATQAMVVAALAWLA
CEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7559343; 11427726; 1597179 [H]