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The map label for this gene is yxbG [H]

Identifier: 119867335

GI number: 119867335

Start: 1381171

End: 1381962

Strand: Reverse

Name: yxbG [H]

Synonym: Mkms_1285

Alternate gene names: 119867335

Gene position: 1381962-1381171 (Counterclockwise)

Preceding gene: 119867337

Following gene: 119867334

Centisome position: 24.09

GC content: 73.36

Gene sequence:

>792_bases
ATGGACATCGACAACAGCGTCGTGGCGATCACCGGCGCCGGTTCCGGGATCGGGCGTGCCCTCGCGGAGTCGTTCGCCGC
CGCCGGCGCCCGCTTGGTGCTCGGCGACGTCGACGATGCCGGACTGGCCGTCACCGCGGAACGTCTGGCGGCCGACGGCG
CCGACGTCAGCACCATGCACGCCGATGCCAGTTCGGCCCACGACATCGCGGCCATGGCCGCTGCGCAACCGGTTGACGTC
TTCGTCGCCAACGCCGGCGTGATGGGCGCCCCCGGACTGGGCACCGAGGCGGACTGGGACCGCATCCTCGACGTGAACCT
GCGCGCGCACGTGCGTGCGGCCACGCTGCTGGTACCGCAGTGGCAGGCCCGCGGCCGCGGCCACTTCGTCAGCGTCGCGT
CGGCCGCCGGACTGCTCACCCAGATCGGCGCCGCGGGCTACGCGGTGAGCAAGCACGCAGCGGTGGGCTTCGCCGAATGG
CTCGCGGTCACCTACGGCGACGACGGCATCGGCGTGACGTGCGTCTGCCCGATGGGGGTCGACACCCCGCTGCTGAACAC
GATCCGCGATGCGGCCGACGCCGAGGTCCGCCTGGGTGCGGAGTCCGTCGTGCAGGCCGGCGCCGTCATCAGCCCGCGCG
AGGTCGCCGATCAGACGGTCGCCGCGATGCGCGACGGCCGGTTCCTGGTGCTGCCCCACCCCGCCGTGCGCGACATGCTC
GCGGGCAAGGTCGCCGACCACGACCGGTGGATCGCCGGGATGCGCCGCTACCAGCGGTCGCTGCGGCAGTGA

Upstream 100 bases:

>100_bases
CGGTTACGCCGCTTCCGGTGACGGTTTTCTTACGTGCCGGAGCGGTCTTGCGCGGTACCCGGCGGACCGCGTCACGACGC
GGGTTCGGCAGGATCGGCCC

Downstream 100 bases:

>100_bases
CCACCCCTGCCGTCGAGCGTCGGGTCGTGCCACGCCTTGCGCGGCGAGCCGTGACACAACCCGACACTCGTCGCTTGTCG
GTGGCAGTTGTCACCATGGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MDIDNSVVAITGAGSGIGRALAESFAAAGARLVLGDVDDAGLAVTAERLAADGADVSTMHADASSAHDIAAMAAAQPVDV
FVANAGVMGAPGLGTEADWDRILDVNLRAHVRAATLLVPQWQARGRGHFVSVASAAGLLTQIGAAGYAVSKHAAVGFAEW
LAVTYGDDGIGVTCVCPMGVDTPLLNTIRDAADAEVRLGAESVVQAGAVISPREVADQTVAAMRDGRFLVLPHPAVRDML
AGKVADHDRWIAGMRRYQRSLRQ

Sequences:

>Translated_263_residues
MDIDNSVVAITGAGSGIGRALAESFAAAGARLVLGDVDDAGLAVTAERLAADGADVSTMHADASSAHDIAAMAAAQPVDV
FVANAGVMGAPGLGTEADWDRILDVNLRAHVRAATLLVPQWQARGRGHFVSVASAAGLLTQIGAAGYAVSKHAAVGFAEW
LAVTYGDDGIGVTCVCPMGVDTPLLNTIRDAADAEVRLGAESVVQAGAVISPREVADQTVAAMRDGRFLVLPHPAVRDML
AGKVADHDRWIAGMRRYQRSLRQ
>Mature_263_residues
MDIDNSVVAITGAGSGIGRALAESFAAAGARLVLGDVDDAGLAVTAERLAADGADVSTMHADASSAHDIAAMAAAQPVDV
FVANAGVMGAPGLGTEADWDRILDVNLRAHVRAATLLVPQWQARGRGHFVSVASAAGLLTQIGAAGYAVSKHAAVGFAEW
LAVTYGDDGIGVTCVCPMGVDTPLLNTIRDAADAEVRLGAESVVQAGAVISPREVADQTVAAMRDGRFLVLPHPAVRDML
AGKVADHDRWIAGMRRYQRSLRQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI142976729, Length=242, Percent_Identity=30.5785123966942, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI40807363, Length=243, Percent_Identity=30.0411522633745, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=32.0855614973262, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI25282469, Length=225, Percent_Identity=31.1111111111111, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI20149619, Length=235, Percent_Identity=32.7659574468085, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI32483357, Length=188, Percent_Identity=30.8510638297872, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI15277342, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=30.0546448087432, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI5031737, Length=186, Percent_Identity=31.7204301075269, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=28.4210526315789, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI4758504, Length=203, Percent_Identity=31.5270935960591, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=221, Percent_Identity=27.1493212669683, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082100, Length=220, Percent_Identity=32.7272727272727, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786812, Length=229, Percent_Identity=28.82096069869, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082160, Length=180, Percent_Identity=30.5555555555556, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=31.7948717948718, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17564282, Length=219, Percent_Identity=30.5936073059361, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193203115, Length=241, Percent_Identity=30.7053941908714, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=242, Percent_Identity=30.1652892561983, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567345, Length=200, Percent_Identity=28, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=187, Percent_Identity=31.5508021390374, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=190, Percent_Identity=27.3684210526316, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=27.979274611399, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581726, Length=249, Percent_Identity=28.5140562248996, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=33.1360946745562, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI23397609, Length=183, Percent_Identity=33.879781420765, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639444, Length=206, Percent_Identity=28.6407766990291, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281364892, Length=235, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=208, Percent_Identity=32.6923076923077, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640492, Length=254, Percent_Identity=24.8031496062992, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28571526, Length=183, Percent_Identity=30.0546448087432, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221510726, Length=242, Percent_Identity=27.6859504132231, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=30, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI18859837, Length=187, Percent_Identity=26.7379679144385, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27071; Mature: 27071

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDNSVVAITGAGSGIGRALAESFAAAGARLVLGDVDDAGLAVTAERLAADGADVSTMH
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHCCCCCCEEEE
ADASSAHDIAAMAAAQPVDVFVANAGVMGAPGLGTEADWDRILDVNLRAHVRAATLLVPQ
CCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHEEECCHHHHEEEEEEEECC
WQARGRGHFVSVASAAGLLTQIGAAGYAVSKHAAVGFAEWLAVTYGDDGIGVTCVCPMGV
HHCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCC
DTPLLNTIRDAADAEVRLGAESVVQAGAVISPREVADQTVAAMRDGRFLVLPHPAVRDML
CHHHHHHHHHHCCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHH
AGKVADHDRWIAGMRRYQRSLRQ
HHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIDNSVVAITGAGSGIGRALAESFAAAGARLVLGDVDDAGLAVTAERLAADGADVSTMH
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHCCCCCCEEEE
ADASSAHDIAAMAAAQPVDVFVANAGVMGAPGLGTEADWDRILDVNLRAHVRAATLLVPQ
CCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHEEECCHHHHEEEEEEEECC
WQARGRGHFVSVASAAGLLTQIGAAGYAVSKHAAVGFAEWLAVTYGDDGIGVTCVCPMGV
HHCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCC
DTPLLNTIRDAADAEVRLGAESVVQAGAVISPREVADQTVAAMRDGRFLVLPHPAVRDML
CHHHHHHHHHHCCCEEECCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHH
AGKVADHDRWIAGMRRYQRSLRQ
HHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377 [H]