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The map label for this gene is lhr [H]

Identifier: 119867334

GI number: 119867334

Start: 1376496

End: 1381067

Strand: Reverse

Name: lhr [H]

Synonym: Mkms_1284

Alternate gene names: 119867334

Gene position: 1381067-1376496 (Counterclockwise)

Preceding gene: 119867335

Following gene: 119867332

Centisome position: 24.07

GC content: 71.39

Gene sequence:

>4572_bases
GTGACGCCACCTCCGACGGCCCATGACGGCCTCTCCCGGTTCAGCCCGCTGACCCGGGAATGGTTCGCGGGCACGTTCGT
CGAACCGACCCCCGCCCAGGCGCAGGCCTGGTCGGCGATCGCCGACGGCGACAACACGCTGGTCATCGCACCGACCGGCT
CGGGTAAGACGCTCGCGGCCTTCCTGTGGGCGATCGACCGGCTGGCGTCGTCCGAGCCTCGGCCCTCCGGAGCGGGCACC
CGCGTGCTCTACGTGTCGCCGCTCAAGGCGCTGGCCGTCGACGTCGAACGCAACCTGCGCACGCCGCTGACCGGCATCGC
CAGGATCGCCGAACGGAACGGACACACCCCACCCGACATCAGCGTGGGGGTCCGCTCCGGGGACACCACACCCGCGCAGC
GCCGCGAACTCGTCACCCGGCCCCCCGACATCCTCATCACCACGCCGGAGTCGCTGTTCCTGATGCTGACGTCGGCGGCC
CGCGACACGCTCGCCGAGGTGCAGACGGTCATCGTCGACGAGGTGCACGCGCTGGCGGCCACCAAGCGCGGCGCACACCT
CGCCCTGTCGCTCGAACGGCTCGACCAGTTGTTGGAGCGGCCCGCACAGCGCATCGGCCTGTCCGCGACGGTCCGCCCGC
CCGAGGAGGTGGCCCGCTTCCTGTCCGGCCACGCCCCGACGACGATCGTCGCCCCGCCGGCCGCCAAGACCTTCGACCTG
TCGGTGCAGGTGCCGGTGCCCGACATGGCCGACCTCGAGAACAACACCATCTGGCCCGACGTCGAGGAGCAGATCGTCGA
CCTGATCGAGGCGCACCGCTCGTCGATCGTGTTCGCCAATTCGCGCCGACTCGCCGAACGGCTGACGTCGCGGCTCAACG
AGATCCACGCCGAGCGCACCGGCACCGCGCTGGACGGCCGCAACGACCGGGTCGGCGCGGGCGCCCCCGCACAGCTGATG
GGCAGCGGTCAGACCTTCGGCGCCGAACCGTTGCTGGCCAAGGCCCACCACGGGTCGGTCAGCAAGGAGCAACGCGCCCT
GGTCGAAGACGACCTCAAGAGCGGGCGGCTCAAGGCCGTCGTCGCGACGTCCAGCCTGGAACTCGGCATCGACATGGGTG
CGGTGGACCTGGTCATCCAGGTGGAGACCCCGCCGTCGGTGGCCAGCGGCCTGCAGCGGGTCGGCCGGGCCGGCCACCAG
GTCGGTGAGATCTCCCAGGGTGTGCTGTTCCCCAAACACCGCACCGACCTGATCGGCTGCGCGATCACCGTGCAGCGCAT
GCTCACCGGTCAGATCGAGACCATGCGGGTACCCGCCAACCCGCTCGACGTGCTCGCCCAGCACACCGTGGCGGCCGCGG
CCCTCGAACCGCTCGACGCCGACCGCTGGTTCGACGCGGTGCGGCGCAGCGCCCCGTTCGCCACGCTGCCCCGCAGCGCG
TTCGAGGCGACGCTCGACCTGCTGTCGGGGAAGTATCCGTCCACGGAGTTCGCCGAACTGCGCCCGCGTCTGGTGTACGA
CCGCGATGCCGGCACGCTGACCGCGCGGCCGGGAGCGCAGCGGCTGGCCGTCACGTCCGGTGGCGCGATCCCCGACCGCG
GCATGTTCACGGTGTACCTCGCCACCGATTCCGAAAAGCCCTCGCGCGTCGGCGAACTCGACGAAGAGATGGTCTACGAA
TCACGGCCCAGCGACGTGATCTCGCTGGGCGCGACGAGTTGGCGGATCACCGAGATCACCCACGACCGGGTGTTGGTGAT
CCCGGCGCCCGGGCAGCCCGCGCGGCTGCCATTCTGGCGCGGCGACGGGGTGGGCCGGCCCGCCGAACTCGGTGCGGCCG
TCGGCGCATTCACCGGGGAACTCGCCGCGTTGGGCGTCGACGCGTTCGCGCAGCGTTGTCAAGCAATGGGTTTCAACGAC
TACGCGACCGACAACCTCTACCGGCTGCTCGACGATCAGCGCCAGGCCACCGGCACGGTGCCCACCGACACCACCTTCGT
GGTCGAACGGTTCCGCGACGAACTCGGCGACTGGCGGATCATCCTGCACTCCCCCTACGGTCTGCGCGTACACGGCCCGC
TCGCGCTCGCGGTCGGCCGCCGGCTGCGCGAGCGCTACGGCATCGACGAGAAACCGACCGCGTCCGACGACGGCATCATC
GTCCGGTTGCCGGACACCGATTTCGAGTCCGGCGGGGTGGTGTCGTTCGCGGACCTCTTCGTCTTCGACGCCGACGAGAT
CGAACCCATCGTCACCGAGGAGGTCGGCGGGTCGGCATTGTTCGCGTCCCGCTTCCGCGAATGCGCGGCCCGTGCGCTGC
TGCTGCCGCGGCGTCATCCCGGTAAGCGGTCGCCGCTCTGGCATCAGCGCCAGCGCGCCGCGCAACTGCTCGACGTCGCC
CGCAAGTACCCGGACTTCCCCATCGTGCTGGAGGCCGTGCGGGAATGCCTGCAGGACGTCTACGACGTGCCCGCCCTGGT
CGAACTGATGCACCGGATCGCCCAGCGCCGGCTGCGCATCGTGGAGGTGGAGACGGTGACACCGTCGCCATTCGCCGCCT
CCCTGCTGTTCGGTTACGTCGGCGCGTTCATGTACGAGGGTGACAGTCCGCTGGCCGAACGCCGCGCGGCCGCACTGTCA
TTGGACAGCACGCTGCTCGCCGAACTGCTCGGTCGCGTCGAACTGCGCGAGTTGCTCGACGCCGACGTCATCGCCGCCAC
GGCACGCCAACTGCAGCACCTCGCCGAGGACCGGCGGGCGAAAGACGCCGAGGGCGTCGCCGACCTGTTGCGCCTGCTGG
GGCCGTTGACCTCCGAGGAGATCGCCGAACGCTCGACCACCGACGATGTCGGCGGGTGGCTCGAAGGCCTGTTGTCGGCG
AAGCGCGTACTGACGGTGTCGTTCGCCGGTCAGAAGTGGTGGGTGGCGATCGAGGACGTCGGGCTGCTGCGCGACGGCGT
CGGGATCGCGGTGCCGGTCGGTGTCCCACTGTCCTTCCTCGATCCGGTGGTCGATCCGCTCGGGGAGCTGATCGGCCGCT
ACGCGCGCACCCACGGCCCGTTCACCACCGCCGAGGCGGCCGCGCGGTTCGGCCTTGGACTGCGGGTCACCGCCGATGTG
CTGGGCCGGCTCACCGTCGACGGCCGGCTGGTGCGGGGTGAGTTCACCGACCTACCTGCCGGGGATCCCGCGGGCAATGA
GCAGTGGTGCGACGGCGACGTCCTGAAGATCCTGCGCCGCCGGTCGCTGGCCGCGCTGCGGGCCCAGGTGGAGCCGGTCA
GCACCGCGGCGTACGCGCGGTTCCTGCCGGCCTGGCAACACGTCGGCTCGACGCACAGTGCGGGCGTGGACGGGCTCGCC
TCGGCGATCGACCAACTCGCCGGGGTGCCGATCCCGGCGTCGGCGGTGGAGCCGCTCGTCCTGTCCCAGCGGGTGCGCGA
CTATCAGCCCGCAATGCTCGACGAACTGCTGGCCAGCGGCGAGATCCTCTGGTCGGGTGCAGGCCAGATCGGCGGCGGTG
ACGGCTGGATCGCCTTCCACCATGCCGACTCCGCACCGCTGACATTGACCGCGCCGGTCGAACTCGAGTTCACCGAGACC
CACCGCGCCATCACCGAGACATTGGCCGCCGGCGGCGCCTACTTCTTCCGCCAGCTCGCCGACGGTGACACCGAAACCTT
CAAAACCGCGCTGTGGGAATTGATCTGGGCGGGGTGGGTCACCGGGGACACCTTCGCCCCGGTCCGGGCGATGCTCTCCG
GCAGCCGGCGGTCCACCGGCAGGCGCGGCGCCCCCGCACACCGGCAGCGGGCACGCCCGCCGCGGTTGAGCAGCTACAGC
ATCGCGCACGCCCAGACGCGCGCGAGCGATCCGACCGTGGCCGGACGCTGGTCGGCGTTACCTGCCGCGGAGCCCGATTC
GACTGTGCGCGCACACTTCTCGGCCGAATTGCTGCTCAACCGCCATGGCGTGCTCACCAAGGGTGCGGCCGTCGCGGAAG
GCGTGCCCGGCGGGTTCGCGATGCTGTACAAGGTGCTGACCGCTTTCGAGGACGCCGGCCGGTGCCAGCGTGGCTACTTC
GTCGAATCGCTGGGCGGCGCGCAGTTCGCGGTCGCCTCGACAGTGGACCGGCTGCGGACCTATCTCGACGAGGTCGACCA
GGAACGCCGCGAGTACCGCGCCGTGGTGCTGGCGGCCGCCGATCCGGCCAACCCGTACGGCGCCGCGCTGCCCTGGCCGG
CCCGCACCGCCGACGGTGACGCCGAGGGCTCCCACCGCCCCGGCCGCAAGGCGGGTGCGCTGGTGGCGCTGGTCGACGGC
GAGCTGGCGTGGTTCCTGGAACGGGGCGGCCGGTCGCTGCTGAGTTTCACCGACGACGCCGACGCCCAGCTGGCCGCCGC
AGCCGCGCTGGCCGATCTGGTCGGCCGCGGCCGGGTGCAGTCGCTGCTGGTCGAGAAGGTCAACGGGGTGGGGGTGCTGG
AACCCGCCCAGGGTGGCGTGCGTGCCGCGGTCCACGACGCCCTGATCGGCGCCGGGTTCACCCGCACCCCGCGCGGCCTG
AGGCTGCGGTGA

Upstream 100 bases:

>100_bases
CCCCTGCCGTCGAGCGTCGGGTCGTGCCACGCCTTGCGCGGCGAGCCGTGACACAACCCGACACTCGTCGCTTGTCGGTG
GCAGTTGTCACCATGGAGGG

Downstream 100 bases:

>100_bases
AAGCGGGTCGGGTCGAGGCGTCAGTCCCGCGGGCCCGCGGCGACGGCGGCGCTGACCTCCGCTGCCGCCTGATCGAGCGT
GTTGAGGGTCATCTCGTCCA

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: Large helicase-related protein [H]

Number of amino acids: Translated: 1523; Mature: 1522

Protein sequence:

>1523_residues
MTPPPTAHDGLSRFSPLTREWFAGTFVEPTPAQAQAWSAIADGDNTLVIAPTGSGKTLAAFLWAIDRLASSEPRPSGAGT
RVLYVSPLKALAVDVERNLRTPLTGIARIAERNGHTPPDISVGVRSGDTTPAQRRELVTRPPDILITTPESLFLMLTSAA
RDTLAEVQTVIVDEVHALAATKRGAHLALSLERLDQLLERPAQRIGLSATVRPPEEVARFLSGHAPTTIVAPPAAKTFDL
SVQVPVPDMADLENNTIWPDVEEQIVDLIEAHRSSIVFANSRRLAERLTSRLNEIHAERTGTALDGRNDRVGAGAPAQLM
GSGQTFGAEPLLAKAHHGSVSKEQRALVEDDLKSGRLKAVVATSSLELGIDMGAVDLVIQVETPPSVASGLQRVGRAGHQ
VGEISQGVLFPKHRTDLIGCAITVQRMLTGQIETMRVPANPLDVLAQHTVAAAALEPLDADRWFDAVRRSAPFATLPRSA
FEATLDLLSGKYPSTEFAELRPRLVYDRDAGTLTARPGAQRLAVTSGGAIPDRGMFTVYLATDSEKPSRVGELDEEMVYE
SRPSDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDGVGRPAELGAAVGAFTGELAALGVDAFAQRCQAMGFND
YATDNLYRLLDDQRQATGTVPTDTTFVVERFRDELGDWRIILHSPYGLRVHGPLALAVGRRLRERYGIDEKPTASDDGII
VRLPDTDFESGGVVSFADLFVFDADEIEPIVTEEVGGSALFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVA
RKYPDFPIVLEAVRECLQDVYDVPALVELMHRIAQRRLRIVEVETVTPSPFAASLLFGYVGAFMYEGDSPLAERRAAALS
LDSTLLAELLGRVELRELLDADVIAATARQLQHLAEDRRAKDAEGVADLLRLLGPLTSEEIAERSTTDDVGGWLEGLLSA
KRVLTVSFAGQKWWVAIEDVGLLRDGVGIAVPVGVPLSFLDPVVDPLGELIGRYARTHGPFTTAEAAARFGLGLRVTADV
LGRLTVDGRLVRGEFTDLPAGDPAGNEQWCDGDVLKILRRRSLAALRAQVEPVSTAAYARFLPAWQHVGSTHSAGVDGLA
SAIDQLAGVPIPASAVEPLVLSQRVRDYQPAMLDELLASGEILWSGAGQIGGGDGWIAFHHADSAPLTLTAPVELEFTET
HRAITETLAAGGAYFFRQLADGDTETFKTALWELIWAGWVTGDTFAPVRAMLSGSRRSTGRRGAPAHRQRARPPRLSSYS
IAHAQTRASDPTVAGRWSALPAAEPDSTVRAHFSAELLLNRHGVLTKGAAVAEGVPGGFAMLYKVLTAFEDAGRCQRGYF
VESLGGAQFAVASTVDRLRTYLDEVDQERREYRAVVLAAADPANPYGAALPWPARTADGDAEGSHRPGRKAGALVALVDG
ELAWFLERGGRSLLSFTDDADAQLAAAAALADLVGRGRVQSLLVEKVNGVGVLEPAQGGVRAAVHDALIGAGFTRTPRGL
RLR

Sequences:

>Translated_1523_residues
MTPPPTAHDGLSRFSPLTREWFAGTFVEPTPAQAQAWSAIADGDNTLVIAPTGSGKTLAAFLWAIDRLASSEPRPSGAGT
RVLYVSPLKALAVDVERNLRTPLTGIARIAERNGHTPPDISVGVRSGDTTPAQRRELVTRPPDILITTPESLFLMLTSAA
RDTLAEVQTVIVDEVHALAATKRGAHLALSLERLDQLLERPAQRIGLSATVRPPEEVARFLSGHAPTTIVAPPAAKTFDL
SVQVPVPDMADLENNTIWPDVEEQIVDLIEAHRSSIVFANSRRLAERLTSRLNEIHAERTGTALDGRNDRVGAGAPAQLM
GSGQTFGAEPLLAKAHHGSVSKEQRALVEDDLKSGRLKAVVATSSLELGIDMGAVDLVIQVETPPSVASGLQRVGRAGHQ
VGEISQGVLFPKHRTDLIGCAITVQRMLTGQIETMRVPANPLDVLAQHTVAAAALEPLDADRWFDAVRRSAPFATLPRSA
FEATLDLLSGKYPSTEFAELRPRLVYDRDAGTLTARPGAQRLAVTSGGAIPDRGMFTVYLATDSEKPSRVGELDEEMVYE
SRPSDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDGVGRPAELGAAVGAFTGELAALGVDAFAQRCQAMGFND
YATDNLYRLLDDQRQATGTVPTDTTFVVERFRDELGDWRIILHSPYGLRVHGPLALAVGRRLRERYGIDEKPTASDDGII
VRLPDTDFESGGVVSFADLFVFDADEIEPIVTEEVGGSALFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVA
RKYPDFPIVLEAVRECLQDVYDVPALVELMHRIAQRRLRIVEVETVTPSPFAASLLFGYVGAFMYEGDSPLAERRAAALS
LDSTLLAELLGRVELRELLDADVIAATARQLQHLAEDRRAKDAEGVADLLRLLGPLTSEEIAERSTTDDVGGWLEGLLSA
KRVLTVSFAGQKWWVAIEDVGLLRDGVGIAVPVGVPLSFLDPVVDPLGELIGRYARTHGPFTTAEAAARFGLGLRVTADV
LGRLTVDGRLVRGEFTDLPAGDPAGNEQWCDGDVLKILRRRSLAALRAQVEPVSTAAYARFLPAWQHVGSTHSAGVDGLA
SAIDQLAGVPIPASAVEPLVLSQRVRDYQPAMLDELLASGEILWSGAGQIGGGDGWIAFHHADSAPLTLTAPVELEFTET
HRAITETLAAGGAYFFRQLADGDTETFKTALWELIWAGWVTGDTFAPVRAMLSGSRRSTGRRGAPAHRQRARPPRLSSYS
IAHAQTRASDPTVAGRWSALPAAEPDSTVRAHFSAELLLNRHGVLTKGAAVAEGVPGGFAMLYKVLTAFEDAGRCQRGYF
VESLGGAQFAVASTVDRLRTYLDEVDQERREYRAVVLAAADPANPYGAALPWPARTADGDAEGSHRPGRKAGALVALVDG
ELAWFLERGGRSLLSFTDDADAQLAAAAALADLVGRGRVQSLLVEKVNGVGVLEPAQGGVRAAVHDALIGAGFTRTPRGL
RLR
>Mature_1522_residues
TPPPTAHDGLSRFSPLTREWFAGTFVEPTPAQAQAWSAIADGDNTLVIAPTGSGKTLAAFLWAIDRLASSEPRPSGAGTR
VLYVSPLKALAVDVERNLRTPLTGIARIAERNGHTPPDISVGVRSGDTTPAQRRELVTRPPDILITTPESLFLMLTSAAR
DTLAEVQTVIVDEVHALAATKRGAHLALSLERLDQLLERPAQRIGLSATVRPPEEVARFLSGHAPTTIVAPPAAKTFDLS
VQVPVPDMADLENNTIWPDVEEQIVDLIEAHRSSIVFANSRRLAERLTSRLNEIHAERTGTALDGRNDRVGAGAPAQLMG
SGQTFGAEPLLAKAHHGSVSKEQRALVEDDLKSGRLKAVVATSSLELGIDMGAVDLVIQVETPPSVASGLQRVGRAGHQV
GEISQGVLFPKHRTDLIGCAITVQRMLTGQIETMRVPANPLDVLAQHTVAAAALEPLDADRWFDAVRRSAPFATLPRSAF
EATLDLLSGKYPSTEFAELRPRLVYDRDAGTLTARPGAQRLAVTSGGAIPDRGMFTVYLATDSEKPSRVGELDEEMVYES
RPSDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDGVGRPAELGAAVGAFTGELAALGVDAFAQRCQAMGFNDY
ATDNLYRLLDDQRQATGTVPTDTTFVVERFRDELGDWRIILHSPYGLRVHGPLALAVGRRLRERYGIDEKPTASDDGIIV
RLPDTDFESGGVVSFADLFVFDADEIEPIVTEEVGGSALFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVAR
KYPDFPIVLEAVRECLQDVYDVPALVELMHRIAQRRLRIVEVETVTPSPFAASLLFGYVGAFMYEGDSPLAERRAAALSL
DSTLLAELLGRVELRELLDADVIAATARQLQHLAEDRRAKDAEGVADLLRLLGPLTSEEIAERSTTDDVGGWLEGLLSAK
RVLTVSFAGQKWWVAIEDVGLLRDGVGIAVPVGVPLSFLDPVVDPLGELIGRYARTHGPFTTAEAAARFGLGLRVTADVL
GRLTVDGRLVRGEFTDLPAGDPAGNEQWCDGDVLKILRRRSLAALRAQVEPVSTAAYARFLPAWQHVGSTHSAGVDGLAS
AIDQLAGVPIPASAVEPLVLSQRVRDYQPAMLDELLASGEILWSGAGQIGGGDGWIAFHHADSAPLTLTAPVELEFTETH
RAITETLAAGGAYFFRQLADGDTETFKTALWELIWAGWVTGDTFAPVRAMLSGSRRSTGRRGAPAHRQRARPPRLSSYSI
AHAQTRASDPTVAGRWSALPAAEPDSTVRAHFSAELLLNRHGVLTKGAAVAEGVPGGFAMLYKVLTAFEDAGRCQRGYFV
ESLGGAQFAVASTVDRLRTYLDEVDQERREYRAVVLAAADPANPYGAALPWPARTADGDAEGSHRPGRKAGALVALVDGE
LAWFLERGGRSLLSFTDDADAQLAAAAALADLVGRGRVQSLLVEKVNGVGVLEPAQGGVRAAVHDALIGAGFTRTPRGLR
LR

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI284005309, Length=398, Percent_Identity=25.6281407035176, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1787942, Length=1568, Percent_Identity=47.9591836734694, Blast_Score=1300, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17537519, Length=411, Percent_Identity=26.7639902676399, Blast_Score=74, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17537127, Length=410, Percent_Identity=22.6829268292683, Blast_Score=71, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320497, Length=378, Percent_Identity=27.7777777777778, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI9755332, Length=400, Percent_Identity=26.25, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321020, Length=399, Percent_Identity=27.3182957393484, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24647182, Length=367, Percent_Identity=23.7057220708447, Blast_Score=72, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 163787; Mature: 163656

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPPTAHDGLSRFSPLTREWFAGTFVEPTPAQAQAWSAIADGDNTLVIAPTGSGKTLAA
CCCCCCCHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHEECCCCEEEEEECCCCCHHHH
FLWAIDRLASSEPRPSGAGTRVLYVSPLKALAVDVERNLRTPLTGIARIAERNGHTPPDI
HHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
SVGVRSGDTTPAQRRELVTRPPDILITTPESLFLMLTSAARDTLAEVQTVIVDEVHALAA
EEEECCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKRGAHLALSLERLDQLLERPAQRIGLSATVRPPEEVARFLSGHAPTTIVAPPAAKTFDL
HCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCEEEE
SVQVPVPDMADLENNTIWPDVEEQIVDLIEAHRSSIVFANSRRLAERLTSRLNEIHAERT
EEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHC
GTALDGRNDRVGAGAPAQLMGSGQTFGAEPLLAKAHHGSVSKEQRALVEDDLKSGRLKAV
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCEEEE
VATSSLELGIDMGAVDLVIQVETPPSVASGLQRVGRAGHQVGEISQGVLFPKHRTDLIGC
EEECCEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHH
AITVQRMLTGQIETMRVPANPLDVLAQHTVAAAALEPLDADRWFDAVRRSAPFATLPRSA
HHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHCCHHH
FEATLDLLSGKYPSTEFAELRPRLVYDRDAGTLTARPGAQRLAVTSGGAIPDRGMFTVYL
HHHHHHHHCCCCCCCHHHHCCCCEEEECCCCEEEECCCCCEEEEECCCCCCCCCEEEEEE
ATDSEKPSRVGELDEEMVYESRPSDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWR
EECCCCCCHHHCCHHHHHHHCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCCEEC
GDGVGRPAELGAAVGAFTGELAALGVDAFAQRCQAMGFNDYATDNLYRLLDDQRQATGTV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
PTDTTFVVERFRDELGDWRIILHSPYGLRVHGPLALAVGRRLRERYGIDEKPTASDDGII
CCCHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VRLPDTDFESGGVVSFADLFVFDADEIEPIVTEEVGGSALFASRFRECAARALLLPRRHP
EEECCCCCCCCCEEEEEHEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
GKRSPLWHQRQRAAQLLDVARKYPDFPIVLEAVRECLQDVYDVPALVELMHRIAQRRLRI
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEE
VEVETVTPSPFAASLLFGYVGAFMYEGDSPLAERRAAALSLDSTLLAELLGRVELRELLD
EEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADVIAATARQLQHLAEDRRAKDAEGVADLLRLLGPLTSEEIAERSTTDDVGGWLEGLLSA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHH
KRVLTVSFAGQKWWVAIEDVGLLRDGVGIAVPVGVPLSFLDPVVDPLGELIGRYARTHGP
HHEEEEEECCCEEEEEEECCHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
FTTAEAAARFGLGLRVTADVLGRLTVDGRLVRGEFTDLPAGDPAGNEQWCDGDVLKILRR
CCHHHHHHHHCCCEEEHHHHHHEECCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
RSLAALRAQVEPVSTAAYARFLPAWQHVGSTHSAGVDGLASAIDQLAGVPIPASAVEPLV
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
LSQRVRDYQPAMLDELLASGEILWSGAGQIGGGDGWIAFHHADSAPLTLTAPVELEFTET
HHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCCEEEECCEEEEEHHH
HRAITETLAAGGAYFFRQLADGDTETFKTALWELIWAGWVTGDTFAPVRAMLSGSRRSTG
HHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
RRGAPAHRQRARPPRLSSYSIAHAQTRASDPTVAGRWSALPAAEPDSTVRAHFSAELLLN
CCCCCHHHHCCCCCCCCCCEEHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RHGVLTKGAAVAEGVPGGFAMLYKVLTAFEDAGRCQRGYFVESLGGAQFAVASTVDRLRT
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHH
YLDEVDQERREYRAVVLAAADPANPYGAALPWPARTADGDAEGSHRPGRKAGALVALVDG
HHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
ELAWFLERGGRSLLSFTDDADAQLAAAAALADLVGRGRVQSLLVEKVNGVGVLEPAQGGV
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCH
RAAVHDALIGAGFTRTPRGLRLR
HHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPPPTAHDGLSRFSPLTREWFAGTFVEPTPAQAQAWSAIADGDNTLVIAPTGSGKTLAA
CCCCCCHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHEECCCCEEEEEECCCCCHHHH
FLWAIDRLASSEPRPSGAGTRVLYVSPLKALAVDVERNLRTPLTGIARIAERNGHTPPDI
HHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
SVGVRSGDTTPAQRRELVTRPPDILITTPESLFLMLTSAARDTLAEVQTVIVDEVHALAA
EEEECCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKRGAHLALSLERLDQLLERPAQRIGLSATVRPPEEVARFLSGHAPTTIVAPPAAKTFDL
HCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCEEEE
SVQVPVPDMADLENNTIWPDVEEQIVDLIEAHRSSIVFANSRRLAERLTSRLNEIHAERT
EEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHC
GTALDGRNDRVGAGAPAQLMGSGQTFGAEPLLAKAHHGSVSKEQRALVEDDLKSGRLKAV
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCEEEE
VATSSLELGIDMGAVDLVIQVETPPSVASGLQRVGRAGHQVGEISQGVLFPKHRTDLIGC
EEECCEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHH
AITVQRMLTGQIETMRVPANPLDVLAQHTVAAAALEPLDADRWFDAVRRSAPFATLPRSA
HHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHCCHHH
FEATLDLLSGKYPSTEFAELRPRLVYDRDAGTLTARPGAQRLAVTSGGAIPDRGMFTVYL
HHHHHHHHCCCCCCCHHHHCCCCEEEECCCCEEEECCCCCEEEEECCCCCCCCCEEEEEE
ATDSEKPSRVGELDEEMVYESRPSDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWR
EECCCCCCHHHCCHHHHHHHCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCCEEC
GDGVGRPAELGAAVGAFTGELAALGVDAFAQRCQAMGFNDYATDNLYRLLDDQRQATGTV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
PTDTTFVVERFRDELGDWRIILHSPYGLRVHGPLALAVGRRLRERYGIDEKPTASDDGII
CCCHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VRLPDTDFESGGVVSFADLFVFDADEIEPIVTEEVGGSALFASRFRECAARALLLPRRHP
EEECCCCCCCCCEEEEEHEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
GKRSPLWHQRQRAAQLLDVARKYPDFPIVLEAVRECLQDVYDVPALVELMHRIAQRRLRI
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEE
VEVETVTPSPFAASLLFGYVGAFMYEGDSPLAERRAAALSLDSTLLAELLGRVELRELLD
EEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADVIAATARQLQHLAEDRRAKDAEGVADLLRLLGPLTSEEIAERSTTDDVGGWLEGLLSA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHH
KRVLTVSFAGQKWWVAIEDVGLLRDGVGIAVPVGVPLSFLDPVVDPLGELIGRYARTHGP
HHEEEEEECCCEEEEEEECCHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
FTTAEAAARFGLGLRVTADVLGRLTVDGRLVRGEFTDLPAGDPAGNEQWCDGDVLKILRR
CCHHHHHHHHCCCEEEHHHHHHEECCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
RSLAALRAQVEPVSTAAYARFLPAWQHVGSTHSAGVDGLASAIDQLAGVPIPASAVEPLV
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
LSQRVRDYQPAMLDELLASGEILWSGAGQIGGGDGWIAFHHADSAPLTLTAPVELEFTET
HHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCCEEEECCEEEEEHHH
HRAITETLAAGGAYFFRQLADGDTETFKTALWELIWAGWVTGDTFAPVRAMLSGSRRSTG
HHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
RRGAPAHRQRARPPRLSSYSIAHAQTRASDPTVAGRWSALPAAEPDSTVRAHFSAELLLN
CCCCCHHHHCCCCCCCCCCEEHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RHGVLTKGAAVAEGVPGGFAMLYKVLTAFEDAGRCQRGYFVESLGGAQFAVASTVDRLRT
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHH
YLDEVDQERREYRAVVLAAADPANPYGAALPWPARTADGDAEGSHRPGRKAGALVALVDG
HHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
ELAWFLERGGRSLLSFTDDADAQLAAAAALADLVGRGRVQSLLVEKVNGVGVLEPAQGGV
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCH
RAAVHDALIGAGFTRTPRGLRLR
HHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7559321; 9097039; 9278503; 1460056 [H]