Click here to switch to the map view.

The map label for this gene is cdd [H]

Identifier: 119867298

GI number: 119867298

Start: 1333976

End: 1334392

Strand: Direct

Name: cdd [H]

Synonym: Mkms_1248

Alternate gene names: 119867298

Gene position: 1333976-1334392 (Clockwise)

Preceding gene: 119867293

Following gene: 119867299

Centisome position: 23.25

GC content: 66.91

Gene sequence:

>417_bases
ATGTCTCCCGAAATCAAGTGGGAAGTGTTGCGGCGCAAGGCAATTGAGGCATCTACGCTGGCGTATGCGCCCTACTCGGG
GTTTCCGGTGGGCGCGGCGGCGCTCGTCGACGATGACCGAATCGTGACCGGATGCAATGTGGAGAATGTCTCATATGGCC
TGGGTCTCTGTGCCGAGTGCAGTGTGGTCTGCGCCCTGCATTCCGGCGGCGGCGGACGCCTGGTCGCGCTGTCGTGTGTG
GGGCCCGATTCCGAGGTGCTGATGCCCTGTGGCCGGTGCCGTCAGGTGCTGCTCGAACACGGCGGTCCCGATCTGCTGAT
CGACCATCCGCACGGTCCGCGGCCGCTCGGGGAACTCCTGCCCGACGCGTTCGGACCCGACGATCTGGCGCGGCGGGCGG
CGGGGGAGAAGCCGTGA

Upstream 100 bases:

>100_bases
GCCCCGCTCAGAGGGCAGAAGTTAGGGTCGCCTATCTGTCGTGCGGGGTCATCCGGGGCGGTCTTCGGAATCCATTCAGA
GGCGGGGTGAAAGAGCGCAA

Downstream 100 bases:

>100_bases
CGGACTTCACTTTCGACGCGCCCCGGCCGATGTCGCATCTCGATGCTCCGACCGTCATCCGGGTCAAACGCGACGGCGGC
GACCTGCCCGACGAGGCGAT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MSPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDRIVTGCNVENVSYGLGLCAECSVVCALHSGGGGRLVALSCV
GPDSEVLMPCGRCRQVLLEHGGPDLLIDHPHGPRPLGELLPDAFGPDDLARRAAGEKP

Sequences:

>Translated_138_residues
MSPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDRIVTGCNVENVSYGLGLCAECSVVCALHSGGGGRLVALSCV
GPDSEVLMPCGRCRQVLLEHGGPDLLIDHPHGPRPLGELLPDAFGPDDLARRAAGEKP
>Mature_137_residues
SPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDRIVTGCNVENVSYGLGLCAECSVVCALHSGGGGRLVALSCVG
PDSEVLMPCGRCRQVLLEHGGPDLLIDHPHGPRPLGELLPDAFGPDDLARRAAGEKP

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=121, Percent_Identity=41.3223140495868, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540514, Length=113, Percent_Identity=43.3628318584071, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551074, Length=128, Percent_Identity=41.40625, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=132, Percent_Identity=38.6363636363636, Blast_Score=84, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19920920, Length=96, Percent_Identity=39.5833333333333, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582741, Length=107, Percent_Identity=40.1869158878505, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582744, Length=110, Percent_Identity=42.7272727272727, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14461; Mature: 14330

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDRIVTGCNVENVSYGLGLCAEC
CCCCHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCC
SVVCALHSGGGGRLVALSCVGPDSEVLMPCGRCRQVLLEHGGPDLLIDHPHGPRPLGELL
EEEEEEECCCCCEEEEEEECCCCCCEECCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHC
PDAFGPDDLARRAAGEKP
CCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDRIVTGCNVENVSYGLGLCAEC
CCCHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCC
SVVCALHSGGGGRLVALSCVGPDSEVLMPCGRCRQVLLEHGGPDLLIDHPHGPRPLGELL
EEEEEEECCCCCEEEEEEECCCCCCEECCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHC
PDAFGPDDLARRAAGEKP
CCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]