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The map label for this gene is hepT [H]

Identifier: 119866839

GI number: 119866839

Start: 833037

End: 834065

Strand: Direct

Name: hepT [H]

Synonym: Mkms_0785

Alternate gene names: 119866839

Gene position: 833037-834065 (Clockwise)

Preceding gene: 119866832

Following gene: 119866840

Centisome position: 14.52

GC content: 69.58

Gene sequence:

>1029_bases
TTGTCACAGTATGTTGGCAGGGTGAGGACACCGGCGACTGTGGTGGCGGGCGTGGACTTCGGCGACGCGGCCTTCGCGGC
CGACGTCCGCGCCGGAGTCGCCCGCATCGAGGATCTGATGTCCACCGAGCTGGGCAAGGCGGACGAGCTGATGGCCGAGG
CCGTTCAGCATCTCTTCCAGGCCGGCGGTAAGCGGTTCCGCCCGCTGTTCACTGTGCTGTCGGCGCGGCTCGGGCCCGAA
CCCGACGCCTGGCAGGTGACGGTGGCGGGTGCGGTGATCGAACTGGTGCACCTGGCGACGCTGTACCACGACGACGTCAT
GGACGAGGCCCAGGTCCGGCGCGGGGCGCCGAGCGCCAACGCCCGCTGGGGCAACAACATCGCCATCCTCGCGGGCGACT
ACCTGTTCGCCACCGCGTCGCGGCTGGTGTCGCGGTTGGGGCCGGAGGCCGTGCGGATCATCGCCGACACGTTCGCCCAA
CTGGTGACCGGTCAGATGCGGGAGACCCGCGGTGCGGTCGAGGGCGTCGACGAGATCGAGCACTACCTCAAGGTCGTCTA
CGAGAAGACGGCCTGCCTGATCGCGGCGTCGGGGCGGTTCGGGGCGACGTTCTCCGGCGCCGACGAGACCCAGATCGAGC
GGTTGGCGCGCCTGGGCGGAATCGTCGGCACGGCGTTCCAGATCTCCGACGACATCATCGACATCGACAGCGATCCCGAC
GAATCCGGCAAGGTTCCGGGCACCGATCTACGTGAGGGTGTTCACACTCTGCCGGTGCTCTACGCGCTGCGGGAGTCCGG
TCCCGACACCGACCGCCTGCGCGAACTGCTCGCCCGGCCCGTCGACAACGACGACGATCTCGCCGAGGCCCTGCGGCTGC
TACGCCGCTCACCAGGCATGGAGCAGGCCAAGGCGACCGTCGCCCGCTACGCGCAGCAGGCCCGCGACGAACTGGCCGCC
CTGCCCGACATGCCGGGAAGGCAGGCGCTGGCCTCACTGGTCGACTACACGATCACCCGCCACGGCTGA

Upstream 100 bases:

>100_bases
TCGATCACCAACACGTCGCGACCGGCGCGGGCCGCCCAGGCCGCGGCAGCCGAACCCGCAGGTCCGGCGCCGACAACGAC
CACATCCGCCCGGGTCTTCA

Downstream 100 bases:

>100_bases
ACATCGCCGGAACCCAGACGGCTGTATGCAGCGTTGGATCAGCGAAGACTCACGAGGAGGTAGCTGATGACGTGGAATCC
GCACGCGAACAGGTTCAAGA

Product: trans-hexaprenyltranstransferase

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSQYVGRVRTPATVVAGVDFGDAAFAADVRAGVARIEDLMSTELGKADELMAEAVQHLFQAGGKRFRPLFTVLSARLGPE
PDAWQVTVAGAVIELVHLATLYHDDVMDEAQVRRGAPSANARWGNNIAILAGDYLFATASRLVSRLGPEAVRIIADTFAQ
LVTGQMRETRGAVEGVDEIEHYLKVVYEKTACLIAASGRFGATFSGADETQIERLARLGGIVGTAFQISDDIIDIDSDPD
ESGKVPGTDLREGVHTLPVLYALRESGPDTDRLRELLARPVDNDDDLAEALRLLRRSPGMEQAKATVARYAQQARDELAA
LPDMPGRQALASLVDYTITRHG

Sequences:

>Translated_342_residues
MSQYVGRVRTPATVVAGVDFGDAAFAADVRAGVARIEDLMSTELGKADELMAEAVQHLFQAGGKRFRPLFTVLSARLGPE
PDAWQVTVAGAVIELVHLATLYHDDVMDEAQVRRGAPSANARWGNNIAILAGDYLFATASRLVSRLGPEAVRIIADTFAQ
LVTGQMRETRGAVEGVDEIEHYLKVVYEKTACLIAASGRFGATFSGADETQIERLARLGGIVGTAFQISDDIIDIDSDPD
ESGKVPGTDLREGVHTLPVLYALRESGPDTDRLRELLARPVDNDDDLAEALRLLRRSPGMEQAKATVARYAQQARDELAA
LPDMPGRQALASLVDYTITRHG
>Mature_341_residues
SQYVGRVRTPATVVAGVDFGDAAFAADVRAGVARIEDLMSTELGKADELMAEAVQHLFQAGGKRFRPLFTVLSARLGPEP
DAWQVTVAGAVIELVHLATLYHDDVMDEAQVRRGAPSANARWGNNIAILAGDYLFATASRLVSRLGPEAVRIIADTFAQL
VTGQMRETRGAVEGVDEIEHYLKVVYEKTACLIAASGRFGATFSGADETQIERLARLGGIVGTAFQISDDIIDIDSDPDE
SGKVPGTDLREGVHTLPVLYALRESGPDTDRLRELLARPVDNDDDLAEALRLLRRSPGMEQAKATVARYAQQARDELAAL
PDMPGRQALASLVDYTITRHG

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=313, Percent_Identity=32.2683706070287, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4758430, Length=275, Percent_Identity=25.4545454545455, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI83700220, Length=275, Percent_Identity=25.4545454545455, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1789578, Length=294, Percent_Identity=31.9727891156463, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1786623, Length=231, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17505681, Length=301, Percent_Identity=31.2292358803987, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319475, Length=295, Percent_Identity=30.8474576271186, Blast_Score=129, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6325188, Length=311, Percent_Identity=23.7942122186495, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651612, Length=293, Percent_Identity=32.4232081911263, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281365769, Length=287, Percent_Identity=26.1324041811847, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24660002, Length=287, Percent_Identity=26.1324041811847, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36925; Mature: 36794

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQYVGRVRTPATVVAGVDFGDAAFAADVRAGVARIEDLMSTELGKADELMAEAVQHLFQ
CCCCHHCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGGKRFRPLFTVLSARLGPEPDAWQVTVAGAVIELVHLATLYHDDVMDEAQVRRGAPSAN
HCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ARWGNNIAILAGDYLFATASRLVSRLGPEAVRIIADTFAQLVTGQMRETRGAVEGVDEIE
CCCCCCEEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
HYLKVVYEKTACLIAASGRFGATFSGADETQIERLARLGGIVGTAFQISDDIIDIDSDPD
HHHHHHHHHHHHEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHEECCCEEECCCCCC
ESGKVPGTDLREGVHTLPVLYALRESGPDTDRLRELLARPVDNDDDLAEALRLLRRSPGM
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCH
EQAKATVARYAQQARDELAALPDMPGRQALASLVDYTITRHG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQYVGRVRTPATVVAGVDFGDAAFAADVRAGVARIEDLMSTELGKADELMAEAVQHLFQ
CCCHHCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGGKRFRPLFTVLSARLGPEPDAWQVTVAGAVIELVHLATLYHDDVMDEAQVRRGAPSAN
HCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ARWGNNIAILAGDYLFATASRLVSRLGPEAVRIIADTFAQLVTGQMRETRGAVEGVDEIE
CCCCCCEEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
HYLKVVYEKTACLIAASGRFGATFSGADETQIERLARLGGIVGTAFQISDDIIDIDSDPD
HHHHHHHHHHHHEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHEECCCEEECCCCCC
ESGKVPGTDLREGVHTLPVLYALRESGPDTDRLRELLARPVDNDDDLAEALRLLRRSPGM
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCH
EQAKATVARYAQQARDELAALPDMPGRQALASLVDYTITRHG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]