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The map label for this gene is nreB [H]

Identifier: 119866656

GI number: 119866656

Start: 656305

End: 657285

Strand: Direct

Name: nreB [H]

Synonym: Mkms_0602

Alternate gene names: 119866656

Gene position: 656305-657285 (Clockwise)

Preceding gene: 119866641

Following gene: 119866657

Centisome position: 11.44

GC content: 69.52

Gene sequence:

>981_bases
ATGAATCGGGCGCGCACCCCCGCGGCCGCACTGTTTCGCCGGGTCTTCTTGATCAACGGCCTCATCTTCACGCTCGGCAC
ACTCGTCCTCGCCGTGTCACCGGCCTCGGTGTCGTCACGCATCCGGCTCACCGAGATCCCGGTCCTGGTCGTCGGTTTGG
CGGTCATTCTGAGCGCCAACGCGTTGCTGCTGCGGTCCAGCCTGGCCCCGCTCGATCGGCTGACCGCGTCCATGCGACGG
GTCGACCCGCCGCGGCGCAGTGACCGTGTCGACGATCGGGGCAGCGGTGATCTGCACCATCTGATCGAATCGTTCAACGC
GATGCTCGACCGGTTGGAGACCGAGCGGACCACGGCCAGCGCATCGGCGCTCGCCGCGCAGGAGAACGAACGGCAGCGCA
TCGCGCGCGAACTGCACGACGAGATCGGGCAGACGTTGACCGTCGCCCTGCTCACGCTCAAACGTGCCGTGGACCGCGCG
CCGGCGGAGATCCGCGGCGAGTTGGAGGAGACCCAGGAGACGGTGCGGGCCAGCCTCGATGAGGTGCGCGGCATCGCCCG
CCGGCTGCGACCGGACGCGCTCGAGGATCTGGGACTGCAGAGCGCGCTCAATGCGCTGTGCAATGAATTCGCCCAGGCGA
CCGGGCTTCCGGTCGTCAAACACATCGCCCTGCCTGCCGCGCGGCTGGCTCCCGACGTCGAGCTGGTCTGCTACCGCATC
GCCCAGGAGTCGCTCACCAACGTCGCGCGCCACGCCGACGCCCGCAAGGTCTGGGTCGACCTGCACGTCGCCGACGATCA
GGTGACGTTGCGGATCGCCGACGACGGGGCGGGCGGTGCGGGTGACGCGGGGGAGGGCGCCGGCATCAGCGGTATGCGGG
AGCGGGCGCTGTTGGTCAACGCGACGCTGACGATCGCGTCTCCACCGGGTGAGGGCACCGAGGTTCGGTTGACCATCCCG
TACCGCGACGGGAGCCGGTGA

Upstream 100 bases:

>100_bases
TCGGCAGGAGACGCGAGGGCCACCATCGGGGCTGACACCCATTTCCGGGGGGCGGTGCCGTGTATGGACATCCTCAGGCC
GGGACGCCACGCTGGTGGGT

Downstream 100 bases:

>100_bases
TGCCGGCGCGGATCCTGCTCGCCGACGACCACGCGCTGGTGCGCAGCGGGTTGCGGCTGATCATCGACGCCGAACCCGAC
CTGCAGGTGGTCGCCGAGGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNRARTPAAALFRRVFLINGLIFTLGTLVLAVSPASVSSRIRLTEIPVLVVGLAVILSANALLLRSSLAPLDRLTASMRR
VDPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTASASALAAQENERQRIARELHDEIGQTLTVALLTLKRAVDRA
PAEIRGELEETQETVRASLDEVRGIARRLRPDALEDLGLQSALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRI
AQESLTNVARHADARKVWVDLHVADDQVTLRIADDGAGGAGDAGEGAGISGMRERALLVNATLTIASPPGEGTEVRLTIP
YRDGSR

Sequences:

>Translated_326_residues
MNRARTPAAALFRRVFLINGLIFTLGTLVLAVSPASVSSRIRLTEIPVLVVGLAVILSANALLLRSSLAPLDRLTASMRR
VDPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTASASALAAQENERQRIARELHDEIGQTLTVALLTLKRAVDRA
PAEIRGELEETQETVRASLDEVRGIARRLRPDALEDLGLQSALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRI
AQESLTNVARHADARKVWVDLHVADDQVTLRIADDGAGGAGDAGEGAGISGMRERALLVNATLTIASPPGEGTEVRLTIP
YRDGSR
>Mature_326_residues
MNRARTPAAALFRRVFLINGLIFTLGTLVLAVSPASVSSRIRLTEIPVLVVGLAVILSANALLLRSSLAPLDRLTASMRR
VDPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTASASALAAQENERQRIARELHDEIGQTLTVALLTLKRAVDRA
PAEIRGELEETQETVRASLDEVRGIARRLRPDALEDLGLQSALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRI
AQESLTNVARHADARKVWVDLHVADDQVTLRIADDGAGGAGDAGEGAGISGMRERALLVNATLTIASPPGEGTEVRLTIP
YRDGSR

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=206, Percent_Identity=34.9514563106796, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787474, Length=200, Percent_Identity=33, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788812, Length=231, Percent_Identity=29.004329004329, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35179; Mature: 35179

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRARTPAAALFRRVFLINGLIFTLGTLVLAVSPASVSSRIRLTEIPVLVVGLAVILSAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEHHHHHHHHHHHHHHHHCC
ALLLRSSLAPLDRLTASMRRVDPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTAS
HHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ASALAAQENERQRIARELHDEIGQTLTVALLTLKRAVDRAPAEIRGELEETQETVRASLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EVRGIARRLRPDALEDLGLQSALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRI
HHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCHHHHHHHH
AQESLTNVARHADARKVWVDLHVADDQVTLRIADDGAGGAGDAGEGAGISGMRERALLVN
HHHHHHHHHHHCCCCEEEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCHHHHCEEEEE
ATLTIASPPGEGTEVRLTIPYRDGSR
EEEEEECCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MNRARTPAAALFRRVFLINGLIFTLGTLVLAVSPASVSSRIRLTEIPVLVVGLAVILSAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEHHHHHHHHHHHHHHHHCC
ALLLRSSLAPLDRLTASMRRVDPPRRSDRVDDRGSGDLHHLIESFNAMLDRLETERTTAS
HHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ASALAAQENERQRIARELHDEIGQTLTVALLTLKRAVDRAPAEIRGELEETQETVRASLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EVRGIARRLRPDALEDLGLQSALNALCNEFAQATGLPVVKHIALPAARLAPDVELVCYRI
HHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCHHHHHHHH
AQESLTNVARHADARKVWVDLHVADDQVTLRIADDGAGGAGDAGEGAGISGMRERALLVN
HHHHHHHHHHHCCCCEEEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCHHHHCEEEEE
ATLTIASPPGEGTEVRLTIPYRDGSR
EEEEEECCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]