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The map label for this gene is gntR [H]

Identifier: 119866179

GI number: 119866179

Start: 135419

End: 136174

Strand: Reverse

Name: gntR [H]

Synonym: Mkms_0123

Alternate gene names: 119866179

Gene position: 136174-135419 (Counterclockwise)

Preceding gene: 119866196

Following gene: 119866176

Centisome position: 2.37

GC content: 69.44

Gene sequence:

>756_bases
ATGGCCAAGGCGCTTCGTGGACAACCCCGTCCGATCACGCCGAAGAACCGGAGAGCACCCGTGAACGCCGCCCCCGTCGC
ACGACGTCCGGCGAGGCGGCGCGCCACTCGCCGCGAACAGCTCTCCGACGAGGTGGCGGGGCATCTGCGTGCGGCGATCA
TGACCGGAGCACTGCGGCCAGGGACGTTCATCCGGCTCGACGAGACGGCCGCGGAGCTGGGCGTGAGCATCACCCCGGTC
CGGGAGGCGCTTCGGACATTGCGCGGCGAGGGGATGGTGCGGCTCGAGCCGCACCGCGGGCACGTCGTGGTGCCGATGAC
GCGCGGGGACATCGAGGACATCTTCTGGCTGCAGGCGACGATCGCGGAGAAATTGGCCGAGGCCGCCACCGAACGGATCA
GCGAGACGCAGATCGAGGAGCTCGAGCAGCTCAACTCCGCGCTCGCCGAGGCGGTCGAGCATCAGGATCCGGAGGAGGTG
GCGTTCGCGGAGTTCGCCTTCCACCGGGCGTTCAACCACGCATCGGGGCGGATCAAGCTCGCGTGGTTCCTGTTGCACGT
GGCGCGGTACCTGCCGCCACTGCTGTATGCGACGGATCCGAGCTGGGGCACGGACGCGGTGGCCAGTCACCGGGAGTTGA
TCGCGGCGCTACGGCGGCGGGACGCGGAGACGGTGGTGCGGTTGACGACGGGGCAGTTCACCGACGGGGCGCAGAGGTTG
ATCGTCCGGCTGGAGAAGATCGGGCTCTGGGACTAG

Upstream 100 bases:

>100_bases
CAGAGGCGTCGGGCTCGGAGGTCAACGTGGGTCGGCTCCATCGTCTCGGGGTTGCGTGTGGTTGATATTTGATCAAACAT
TGGATGGCCCCGGTCACACT

Downstream 100 bases:

>100_bases
GCAACCCGGCTTCGCGCGCGTCTATGCGCTGCCGGCGCCCAAATGTTCGGCCCGGGCCTTGAGGTTGTCGGCCAGATAGT
CCAGCGTCTCGCCGATCGCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: P28 protein [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAKALRGQPRPITPKNRRAPVNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRPGTFIRLDETAAELGVSITPV
REALRTLRGEGMVRLEPHRGHVVVPMTRGDIEDIFWLQATIAEKLAEAATERISETQIEELEQLNSALAEAVEHQDPEEV
AFAEFAFHRAFNHASGRIKLAWFLLHVARYLPPLLYATDPSWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRL
IVRLEKIGLWD

Sequences:

>Translated_251_residues
MAKALRGQPRPITPKNRRAPVNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRPGTFIRLDETAAELGVSITPV
REALRTLRGEGMVRLEPHRGHVVVPMTRGDIEDIFWLQATIAEKLAEAATERISETQIEELEQLNSALAEAVEHQDPEEV
AFAEFAFHRAFNHASGRIKLAWFLLHVARYLPPLLYATDPSWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRL
IVRLEKIGLWD
>Mature_250_residues
AKALRGQPRPITPKNRRAPVNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRPGTFIRLDETAAELGVSITPVR
EALRTLRGEGMVRLEPHRGHVVVPMTRGDIEDIFWLQATIAEKLAEAATERISETQIEELEQLNSALAEAVEHQDPEEVA
FAEFAFHRAFNHASGRIKLAWFLLHVARYLPPLLYATDPSWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRLI
VRLEKIGLWD

Specific function: Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081914, Length=187, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28090; Mature: 27958

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKALRGQPRPITPKNRRAPVNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTFIRLDETAAELGVSITPVREALRTLRGEGMVRLEPHRGHVVVPMTRGDIEDIFWLQAT
CCEEEECHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCHHHHHHHHHH
IAEKLAEAATERISETQIEELEQLNSALAEAVEHQDPEEVAFAEFAFHRAFNHASGRIKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHH
AWFLLHVARYLPPLLYATDPSWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRL
HHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCHHHHHH
IVRLEKIGLWD
HHHHHHHCCCC
>Mature Secondary Structure 
AKALRGQPRPITPKNRRAPVNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTFIRLDETAAELGVSITPVREALRTLRGEGMVRLEPHRGHVVVPMTRGDIEDIFWLQAT
CCEEEECHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCHHHHHHHHHH
IAEKLAEAATERISETQIEELEQLNSALAEAVEHQDPEEVAFAEFAFHRAFNHASGRIKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHH
AWFLLHVARYLPPLLYATDPSWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRL
HHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCHHHHHH
IVRLEKIGLWD
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]