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The map label for this gene is ftsK [H]

Identifier: 119855377

GI number: 119855377

Start: 193111

End: 194553

Strand: Reverse

Name: ftsK [H]

Synonym: Mkms_5993

Alternate gene names: 119855377

Gene position: 194553-193111 (Counterclockwise)

Preceding gene: 119855378

Following gene: 119855376

Centisome position: 89.75

GC content: 67.01

Gene sequence:

>1443_bases
ATGACATCGAAGAAGAACACCACCAACAATGGACCGGACAATAACGACTGGTTCGCAGAACTAGTCGTGTCGCTGTTCAC
CGCGGCCGGGTATGTGCTGTGGTGGGCGGTGCTGTTCCCGGCGATCAGCCTGCCCATCATCGCCAGCCTCGTCCTTGCCA
TCAGCCACGGCCCGCGCGTGGGCCTGATCTGCGCGATCGTGTGCAGTGCCGCGTATGCGGTCTGGGCCTGGCTCCAACCG
GGATCGTTTCGCGCCTGGGTGACCGAACCGGTGCGCCGGCGCTGGCTCACTTGGTCGCGCTACGCCCGGACCTGGGAATC
GACCTGCACCCTGCACGGCTTGACCAACACCCTCAGCGGACGCACCCTCACCCCGGCCCTGCGCGCGGTGACGATCGGTA
AAACCACCGATGTGCTGGCGGTGCGGATCGTCACCGGCCAGTCCGTGGCCGATTGGCATAAACAGTCCGACGCGCTGGCC
GCCGCGTGGCGCGCCGACCGCATCGGCATCACCGCCACCTCGCCTGGCGAACTGCGCATCACGTTAATGCGCGCAGACGT
GCTGGCTGAACCGATCGCCCTGCCCATGCCCACCCCGGCCACTCCGGTCGATCTGGTGTCGGTGCGGGTCGGGATCACCG
AAATGCGTCATTGGTGGCAGGTGCCGCTGCTCGGTCACCACGTGCTGATCGCCGGGGCAACCGGCGCAGGTAAAGGCTCA
GTGCTGTGGTCGTTGATCGCCGGCATTGCCCCCGCAGTGAAGACCGGGCTGGTCCGGTTGTGTGTCATCGACCCCAAAGG
CGGCATGGAACTCGGTGCCGGCGCACCCATGTTCACCGTGTTCACCCACGACGCCACCGACACCACCCTGGAGCTGCTGC
GCCAGCTCGCCACGGTGATGCACGCCCGGGCGAATCGGCTGCGCGGCCACACCCGCCTACACACCCCCACGACGTCGGAG
CCGTTGTTCGTGGTGGTGATCGATGAGATCGCCGCACTGACCGCCTATGTCACCGACCGCAAGGTCCGCACCGAAATTGA
ACAACTCCTGGGCTTGCTGCTCTCCCAAGGCCGCGCAGTCGGCATCAGCGTGGTCGCCGCGGTCCAAGACCCGGCCAAAG
ACACCCTGCCGGTACGGCAATTATTCACGGTGCGGATCGGGTTGCGGCTGACCGAAGCCACCCAAACCACCATGGTCCTC
GGCCAAGGGGCACGCGATGCCGGGGCCGAATGCGACCGCATCCCCGACGCCACACCCGGGGTGGGCTACATGATGGTGGA
CGGCACCGCCCAGGCCCAGCGGGTGCGGGCCTTCCACGTCACCGACCACGACATCACCGCCCTGGCCACCCGGTTCCGCC
GACCCGCGCGCCGACCGAACAACAACCACCAGCCACGCAGCACCGATACCGGCCACACCGCGGGTGAGGGTAGCGGTGAA
TAG

Upstream 100 bases:

>100_bases
CGCAGAAGTAACCCATAGCGGGTGTGGGGTGCGGTGAACCGATCACTGCACCCCCCCGCGGGCATTGCTGTCGACCACAC
GCTCACGGAGGACATCTCTC

Downstream 100 bases:

>100_bases
CTCCACGACATCGGCGCAGCTTGTTTTACCGGGCGTGCCGGATACGGTTGACACCGCTCGGGTGGTCGAGCAGATGGTGC
GGCGCGCCGCCTCGATGGGA

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTSKKNTTNNGPDNNDWFAELVVSLFTAAGYVLWWAVLFPAISLPIIASLVLAISHGPRVGLICAIVCSAAYAVWAWLQP
GSFRAWVTEPVRRRWLTWSRYARTWESTCTLHGLTNTLSGRTLTPALRAVTIGKTTDVLAVRIVTGQSVADWHKQSDALA
AAWRADRIGITATSPGELRITLMRADVLAEPIALPMPTPATPVDLVSVRVGITEMRHWWQVPLLGHHVLIAGATGAGKGS
VLWSLIAGIAPAVKTGLVRLCVIDPKGGMELGAGAPMFTVFTHDATDTTLELLRQLATVMHARANRLRGHTRLHTPTTSE
PLFVVVIDEIAALTAYVTDRKVRTEIEQLLGLLLSQGRAVGISVVAAVQDPAKDTLPVRQLFTVRIGLRLTEATQTTMVL
GQGARDAGAECDRIPDATPGVGYMMVDGTAQAQRVRAFHVTDHDITALATRFRRPARRPNNNHQPRSTDTGHTAGEGSGE

Sequences:

>Translated_480_residues
MTSKKNTTNNGPDNNDWFAELVVSLFTAAGYVLWWAVLFPAISLPIIASLVLAISHGPRVGLICAIVCSAAYAVWAWLQP
GSFRAWVTEPVRRRWLTWSRYARTWESTCTLHGLTNTLSGRTLTPALRAVTIGKTTDVLAVRIVTGQSVADWHKQSDALA
AAWRADRIGITATSPGELRITLMRADVLAEPIALPMPTPATPVDLVSVRVGITEMRHWWQVPLLGHHVLIAGATGAGKGS
VLWSLIAGIAPAVKTGLVRLCVIDPKGGMELGAGAPMFTVFTHDATDTTLELLRQLATVMHARANRLRGHTRLHTPTTSE
PLFVVVIDEIAALTAYVTDRKVRTEIEQLLGLLLSQGRAVGISVVAAVQDPAKDTLPVRQLFTVRIGLRLTEATQTTMVL
GQGARDAGAECDRIPDATPGVGYMMVDGTAQAQRVRAFHVTDHDITALATRFRRPARRPNNNHQPRSTDTGHTAGEGSGE
>Mature_479_residues
TSKKNTTNNGPDNNDWFAELVVSLFTAAGYVLWWAVLFPAISLPIIASLVLAISHGPRVGLICAIVCSAAYAVWAWLQPG
SFRAWVTEPVRRRWLTWSRYARTWESTCTLHGLTNTLSGRTLTPALRAVTIGKTTDVLAVRIVTGQSVADWHKQSDALAA
AWRADRIGITATSPGELRITLMRADVLAEPIALPMPTPATPVDLVSVRVGITEMRHWWQVPLLGHHVLIAGATGAGKGSV
LWSLIAGIAPAVKTGLVRLCVIDPKGGMELGAGAPMFTVFTHDATDTTLELLRQLATVMHARANRLRGHTRLHTPTTSEP
LFVVVIDEIAALTAYVTDRKVRTEIEQLLGLLLSQGRAVGISVVAAVQDPAKDTLPVRQLFTVRIGLRLTEATQTTMVLG
QGARDAGAECDRIPDATPGVGYMMVDGTAQAQRVRAFHVTDHDITALATRFRRPARRPNNNHQPRSTDTGHTAGEGSGE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 51877; Mature: 51746

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKKNTTNNGPDNNDWFAELVVSLFTAAGYVLWWAVLFPAISLPIIASLVLAISHGPRV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GLICAIVCSAAYAVWAWLQPGSFRAWVTEPVRRRWLTWSRYARTWESTCTLHGLTNTLSG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHCCCC
RTLTPALRAVTIGKTTDVLAVRIVTGQSVADWHKQSDALAAAWRADRIGITATSPGELRI
CEECCHHHEEEECCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHCCCEEEEECCCCCEEE
TLMRADVLAEPIALPMPTPATPVDLVSVRVGITEMRHWWQVPLLGHHVLIAGATGAGKGS
EEEEHHHHHCCCCCCCCCCCCCHHHHEEEHHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
VLWSLIAGIAPAVKTGLVRLCVIDPKGGMELGAGAPMFTVFTHDATDTTLELLRQLATVM
HHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
HARANRLRGHTRLHTPTTSEPLFVVVIDEIAALTAYVTDRKVRTEIEQLLGLLLSQGRAV
HHHHHHHCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
GISVVAAVQDPAKDTLPVRQLFTVRIGLRLTEATQTTMVLGQGARDAGAECDRIPDATPG
EEEEEEEECCCCCCCCHHHHHHHHHCCEEEECCHHEEEEEECCCCCCCCCCCCCCCCCCC
VGYMMVDGTAQAQRVRAFHVTDHDITALATRFRRPARRPNNNHQPRSTDTGHTAGEGSGE
CEEEEECCCCHHHHEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSKKNTTNNGPDNNDWFAELVVSLFTAAGYVLWWAVLFPAISLPIIASLVLAISHGPRV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GLICAIVCSAAYAVWAWLQPGSFRAWVTEPVRRRWLTWSRYARTWESTCTLHGLTNTLSG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHCCCC
RTLTPALRAVTIGKTTDVLAVRIVTGQSVADWHKQSDALAAAWRADRIGITATSPGELRI
CEECCHHHEEEECCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHCCCEEEEECCCCCEEE
TLMRADVLAEPIALPMPTPATPVDLVSVRVGITEMRHWWQVPLLGHHVLIAGATGAGKGS
EEEEHHHHHCCCCCCCCCCCCCHHHHEEEHHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
VLWSLIAGIAPAVKTGLVRLCVIDPKGGMELGAGAPMFTVFTHDATDTTLELLRQLATVM
HHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
HARANRLRGHTRLHTPTTSEPLFVVVIDEIAALTAYVTDRKVRTEIEQLLGLLLSQGRAV
HHHHHHHCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
GISVVAAVQDPAKDTLPVRQLFTVRIGLRLTEATQTTMVLGQGARDAGAECDRIPDATPG
EEEEEEEECCCCCCCCHHHHHHHHHCCEEEECCHHEEEEEECCCCCCCCCCCCCCCCCCC
VGYMMVDGTAQAQRVRAFHVTDHDITALATRFRRPARRPNNNHQPRSTDTGHTAGEGSGE
CEEEEECCCCHHHHEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]