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The map label for this gene is insF1 [H]

Identifier: 119855374

GI number: 119855374

Start: 191311

End: 192138

Strand: Reverse

Name: insF1 [H]

Synonym: Mkms_5990

Alternate gene names: 119855374

Gene position: 192138-191311 (Counterclockwise)

Preceding gene: 119855375

Following gene: 119855373

Centisome position: 88.64

GC content: 64.01

Gene sequence:

>828_bases
GTGGCGGTGACGTGCCGGGTACTCAAGCTCGCCCGCCAGCCCTACTACCGCTGGCGGGCCCATCCGGTCACCGACGCCGA
AATCGTCGAGGCCTACCGGGCCAACGCGCTGTTCGACGCCCATAAAGACGATCCCGAGTTCGGGTACCGCTATCTGGTCG
AGGAGGCCCGCGATGCTGGTGAGCCGATGGCCGAGCGCACCGCATGGCGGATCTGCTCTCAGCAGGGGTTGTGGAGCGTG
TTCGGAAAGAAGCGCGGCAAGAACGGCAAACCCGGACCACCAGTGCACGATGATCTGGTCGAACGCGACTTCACCGCTAG
TGAACCAAACGCGTTGTGGCTCAGTGACATCACCGAGCATCGCACGGGTGAGGGCAAGCTCTACCTGTGCGCGATCAAGG
ACGTGTTCTCCAACCGCATCGTCGGGTATTCGATCGACTCCCGGATGAAGTCCCGGTTGGCTACTGCCGCGCTCAGTAGT
GCGGTGGCACGCCGCGGGGATGTGGACGGTTGCATTCTGCACAGCGACCGCGGCAGTCAATTTCGAAGCCGAAAGTTCGT
CCACGCCCTGCACCATCACGGCATGGTCGGCTCGATGGGTCGTGTCGGGGCGGCCGGCGACAACGCGGCCATGGAGAGCT
TCTTCAGCCTGCTGCAGAAGAACGTCCTGGACCGCCGTCGGTGGGACACCCGCGAGCAACTACGCATCGCCATCGTGATC
TGGATCGAACGCACCTACCACCGCCGCCGACGACAGCTCACCCTCGGGCGGTTGACCCCGATCGAATTCGAAGCAATCAT
GACCACGCCGGCCAGTCAGGCCGCGTGA

Upstream 100 bases:

>100_bases
ACGAAATCTTGCGCCGGGCGGCCGCGTACTTGTCGCAGGCCAATCTGCCGGGAAAAGGCTCTACCCGCTCGTAAGTGAGC
TCGCCGCCGACGGGATTCCC

Downstream 100 bases:

>100_bases
CGCAATCTGTCACCTGATCGTGCAGCAGACCCCAGGATCAAAGAATCCGTACCCGAGGACCAGATCGCGAAGTACGACTC
TGATCTACGCGAAGGGTTCA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MAVTCRVLKLARQPYYRWRAHPVTDAEIVEAYRANALFDAHKDDPEFGYRYLVEEARDAGEPMAERTAWRICSQQGLWSV
FGKKRGKNGKPGPPVHDDLVERDFTASEPNALWLSDITEHRTGEGKLYLCAIKDVFSNRIVGYSIDSRMKSRLATAALSS
AVARRGDVDGCILHSDRGSQFRSRKFVHALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWDTREQLRIAIVI
WIERTYHRRRRQLTLGRLTPIEFEAIMTTPASQAA

Sequences:

>Translated_275_residues
MAVTCRVLKLARQPYYRWRAHPVTDAEIVEAYRANALFDAHKDDPEFGYRYLVEEARDAGEPMAERTAWRICSQQGLWSV
FGKKRGKNGKPGPPVHDDLVERDFTASEPNALWLSDITEHRTGEGKLYLCAIKDVFSNRIVGYSIDSRMKSRLATAALSS
AVARRGDVDGCILHSDRGSQFRSRKFVHALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWDTREQLRIAIVI
WIERTYHRRRRQLTLGRLTPIEFEAIMTTPASQAA
>Mature_274_residues
AVTCRVLKLARQPYYRWRAHPVTDAEIVEAYRANALFDAHKDDPEFGYRYLVEEARDAGEPMAERTAWRICSQQGLWSVF
GKKRGKNGKPGPPVHDDLVERDFTASEPNALWLSDITEHRTGEGKLYLCAIKDVFSNRIVGYSIDSRMKSRLATAALSSA
VARRGDVDGCILHSDRGSQFRSRKFVHALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWDTREQLRIAIVIW
IERTYHRRRRQLTLGRLTPIEFEAIMTTPASQAA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=240, Percent_Identity=30.4166666666667, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1788405, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787263, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786753, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786570, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786490, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789981, Length=235, Percent_Identity=30.2127659574468, Blast_Score=121, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31270; Mature: 31139

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTCRVLKLARQPYYRWRAHPVTDAEIVEAYRANALFDAHKDDPEFGYRYLVEEARDAG
CCHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
EPMAERTAWRICSQQGLWSVFGKKRGKNGKPGPPVHDDLVERDFTASEPNALWLSDITEH
CCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCEEEHHHHHHC
RTGEGKLYLCAIKDVFSNRIVGYSIDSRMKSRLATAALSSAVARRGDVDGCILHSDRGSQ
CCCCCCEEEEEEHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
FRSRKFVHALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWDTREQLRIAIVI
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEE
WIERTYHRRRRQLTLGRLTPIEFEAIMTTPASQAA
EEHHHHHHHHHHHHHCCCCCCEEHEEEECCHHCCC
>Mature Secondary Structure 
AVTCRVLKLARQPYYRWRAHPVTDAEIVEAYRANALFDAHKDDPEFGYRYLVEEARDAG
CHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
EPMAERTAWRICSQQGLWSVFGKKRGKNGKPGPPVHDDLVERDFTASEPNALWLSDITEH
CCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCEEEHHHHHHC
RTGEGKLYLCAIKDVFSNRIVGYSIDSRMKSRLATAALSSAVARRGDVDGCILHSDRGSQ
CCCCCCEEEEEEHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
FRSRKFVHALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWDTREQLRIAIVI
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEE
WIERTYHRRRRQLTLGRLTPIEFEAIMTTPASQAA
EEHHHHHHHHHHHHHCCCCCCEEHEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]