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The map label for this gene is nisX1 [H]

Identifier: 119855210

GI number: 119855210

Start: 35038

End: 35937

Strand: Reverse

Name: nisX1 [H]

Synonym: Mkms_5824

Alternate gene names: 119855210

Gene position: 35937-35038 (Counterclockwise)

Preceding gene: 119855211

Following gene: 119855208

Centisome position: 16.58

GC content: 66.44

Gene sequence:

>900_bases
GTGAGCCGCTTCCAGTTCGTCGCCGACCACCGAGACACCTTCGAGGTGAAGTGGCTGTGTGCGGTCGTGGAGGTCGCACG
ATCATCATTTTACGCGTGGCTGGCCGCCGCGGACGGTCGTGCCGCCCGCCGGGCTGCTGACGAGGTGCTCGAGGCGCGGA
TCCGTACTGTGCACGACACCGACAACACCTATGGGGCGCCGCGGATCACCGCCGAGCTCAACGACGGCGCACCGCCAGAT
GAGCGGGTCAATCACAAGCGGGTGGCCCGGGTGATGCGCACCGCGGGGATCGCCGGCTACCGGCGTCGGCGCCGGGTCAA
GACCACGCAGTCCGATCCGGCCAACCAGAAGGTGCCTGACCTTCTCAAGCGGGACTTCACCGCCGCGCAGGTCAACACCC
GCTATGTCGGCGACATCACCTACTTGCCGCTGGCCACCGGCGGCAACCTCTACCTGGCCACGGTGATCGACTGCTGTTCA
CGCCGTGTCACCGGCTGGGCGATCGCCGATCACATGCGCACCGAACTCGTCGCCGACGCCCTTAGCGCTGCGACCGCACT
GCGGGGGTCGATGGCCGGTGCGGTGTTCCACACGGACCACGGAAGTCAGTACACATCAAGGGATTTCGCCACACTGTGCG
GCGAGATGGGTGTCATTCAGTCGATGGGCGGTGTGGGGTCCAGTGCCGACAATGCGTTGGCCGAATCGTTCAACGGCACC
CTCAAACGCGAAGTCCTGCAAGACCGTGCCTGCTGGCCCGACGCGGCGACCTGCCGCCGGGAGGTGTTCCGATGGCTGAC
CCGCTACAACACCCAACGGCGGCACTCCCACTGCCGCTATTCCAGCCCCGCCATCTACGAAAGGACCCTGACACCGGCTA
CGCTGCCCGAAGCCGCCTAA

Upstream 100 bases:

>100_bases
GGGCCGAGAATCAGGCGCTGCGGGCGGATAAGACTCGGTTGAGCACCGAGCGTGACATTCTGCGGTCGGCGGCCAAGTAT
TTCGCCGGGGAGACGAACTG

Downstream 100 bases:

>100_bases
CCACAAATCCCGTGTCCACCACTTGGGGGCAAGGCCCTCTGACCGGTTGTCCAACGACAAGGGCGCAGTTCTCGTTGAGA
CTTGTTGAGAATTGTCTGTC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSRFQFVADHRDTFEVKWLCAVVEVARSSFYAWLAAADGRAARRAADEVLEARIRTVHDTDNTYGAPRITAELNDGAPPD
ERVNHKRVARVMRTAGIAGYRRRRRVKTTQSDPANQKVPDLLKRDFTAAQVNTRYVGDITYLPLATGGNLYLATVIDCCS
RRVTGWAIADHMRTELVADALSAATALRGSMAGAVFHTDHGSQYTSRDFATLCGEMGVIQSMGGVGSSADNALAESFNGT
LKREVLQDRACWPDAATCRREVFRWLTRYNTQRRHSHCRYSSPAIYERTLTPATLPEAA

Sequences:

>Translated_299_residues
MSRFQFVADHRDTFEVKWLCAVVEVARSSFYAWLAAADGRAARRAADEVLEARIRTVHDTDNTYGAPRITAELNDGAPPD
ERVNHKRVARVMRTAGIAGYRRRRRVKTTQSDPANQKVPDLLKRDFTAAQVNTRYVGDITYLPLATGGNLYLATVIDCCS
RRVTGWAIADHMRTELVADALSAATALRGSMAGAVFHTDHGSQYTSRDFATLCGEMGVIQSMGGVGSSADNALAESFNGT
LKREVLQDRACWPDAATCRREVFRWLTRYNTQRRHSHCRYSSPAIYERTLTPATLPEAA
>Mature_298_residues
SRFQFVADHRDTFEVKWLCAVVEVARSSFYAWLAAADGRAARRAADEVLEARIRTVHDTDNTYGAPRITAELNDGAPPDE
RVNHKRVARVMRTAGIAGYRRRRRVKTTQSDPANQKVPDLLKRDFTAAQVNTRYVGDITYLPLATGGNLYLATVIDCCSR
RVTGWAIADHMRTELVADALSAATALRGSMAGAVFHTDHGSQYTSRDFATLCGEMGVIQSMGGVGSSADNALAESFNGTL
KREVLQDRACWPDAATCRREVFRWLTRYNTQRRHSHCRYSSPAIYERTLTPATLPEAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=246, Percent_Identity=32.9268292682927, Blast_Score=129, Evalue=5e-30,
Organism=Escherichia coli, GI1788405, Length=290, Percent_Identity=33.448275862069, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787263, Length=290, Percent_Identity=33.448275862069, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786753, Length=290, Percent_Identity=33.448275862069, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786570, Length=290, Percent_Identity=33.448275862069, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786490, Length=290, Percent_Identity=33.448275862069, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789981, Length=264, Percent_Identity=28.7878787878788, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790724, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789424, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789224, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788305, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787669, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786558, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33206; Mature: 33074

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFQFVADHRDTFEVKWLCAVVEVARSSFYAWLAAADGRAARRAADEVLEARIRTVHDT
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCC
DNTYGAPRITAELNDGAPPDERVNHKRVARVMRTAGIAGYRRRRRVKTTQSDPANQKVPD
CCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LLKRDFTAAQVNTRYVGDITYLPLATGGNLYLATVIDCCSRRVTGWAIADHMRTELVADA
HHHHCCHHHHCCCEEECCEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LSAATALRGSMAGAVFHTDHGSQYTSRDFATLCGEMGVIQSMGGVGSSADNALAESFNGT
HHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHH
LKREVLQDRACWPDAATCRREVFRWLTRYNTQRRHSHCRYSSPAIYERTLTPATLPEAA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHECCCCCCCCCCCC
>Mature Secondary Structure 
SRFQFVADHRDTFEVKWLCAVVEVARSSFYAWLAAADGRAARRAADEVLEARIRTVHDT
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCC
DNTYGAPRITAELNDGAPPDERVNHKRVARVMRTAGIAGYRRRRRVKTTQSDPANQKVPD
CCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LLKRDFTAAQVNTRYVGDITYLPLATGGNLYLATVIDCCSRRVTGWAIADHMRTELVADA
HHHHCCHHHHCCCEEECCEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LSAATALRGSMAGAVFHTDHGSQYTSRDFATLCGEMGVIQSMGGVGSSADNALAESFNGT
HHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHH
LKREVLQDRACWPDAATCRREVFRWLTRYNTQRRHSHCRYSSPAIYERTLTPATLPEAA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]