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The map label for this gene is 119855124

Identifier: 119855124

GI number: 119855124

Start: 246635

End: 247285

Strand: Reverse

Name: 119855124

Synonym: Mkms_5737

Alternate gene names: NA

Gene position: 247285-246635 (Counterclockwise)

Preceding gene: 119855125

Following gene: 119855122

Centisome position: 81.86

GC content: 66.97

Gene sequence:

>651_bases
ATGGGTGAGGCCGCCTCCGCCGACGCGACTTTCGCGTTCGTCGATCTGTCCGGTTTCACCGCCCTGACCGAAATTTGCGG
CGACGAGCAAGCCGCTCACCTCGCCGGACGGCTAGTCGAACTGACGCGTGACTCGTTGGCTCTCGATGTCACGCTGGTGA
AGGCCATGGGTGATGCCGTGATGCTTCACGCCCACGACCCCGACACGATGATGGCGACCATCCTTGACCTCGCCGACCGC
GCCGCCGACGAGGACGGCTTCCTCGGACTACGCGCCGGAATTCACCACGGCAGCGCAGTCCAACGGCACCACGACTACTT
CGGCGATGCCGTCAACACCGCCGCACGCGTCACCGCACTCGCAGGCGCCGGGCACGCCGTCATCACCGAACCGATCCTGA
CCGCGTGTGAAGCGCGCGGCGTCGCAGCCCACCCGCTGGGCGAGACCGAGCTACGCAATATCAGCGCCCCAGTGGCGGTG
TACAGGGTGCAGCTACCGCCGCCGCAATACCCCACCGATCCGGTCTGCGGCATCCGCCTCGACCCACGCACCGCCACCCA
CCATCTGCGTCACAACGACCATGATCTCTGGTTCTGCTCCGACCGCTGCGCCCGGCGCTTCGCAGCACACCCCGCCATGG
ACGAGATCTGA

Upstream 100 bases:

>100_bases
CGGGTCGGGCGCTTCCTGCCCGGATTGGGGCGCCTGCGCACCGGCGGTCACGACACCACCACAGTCAGACACACCGATCG
CGAAGCCGACGGTAGACAGC

Downstream 100 bases:

>100_bases
CGCCACCACCTGACACCCAGTCAGCGGCAGCGCAACCTCGCCGCCACCCGCCCACCGATCGCCGGAGTCCTCGAACGCTG
GGAACACCTGTTGCGTGTCC

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MGEAASADATFAFVDLSGFTALTEICGDEQAAHLAGRLVELTRDSLALDVTLVKAMGDAVMLHAHDPDTMMATILDLADR
AADEDGFLGLRAGIHHGSAVQRHHDYFGDAVNTAARVTALAGAGHAVITEPILTACEARGVAAHPLGETELRNISAPVAV
YRVQLPPPQYPTDPVCGIRLDPRTATHHLRHNDHDLWFCSDRCARRFAAHPAMDEI

Sequences:

>Translated_216_residues
MGEAASADATFAFVDLSGFTALTEICGDEQAAHLAGRLVELTRDSLALDVTLVKAMGDAVMLHAHDPDTMMATILDLADR
AADEDGFLGLRAGIHHGSAVQRHHDYFGDAVNTAARVTALAGAGHAVITEPILTACEARGVAAHPLGETELRNISAPVAV
YRVQLPPPQYPTDPVCGIRLDPRTATHHLRHNDHDLWFCSDRCARRFAAHPAMDEI
>Mature_215_residues
GEAASADATFAFVDLSGFTALTEICGDEQAAHLAGRLVELTRDSLALDVTLVKAMGDAVMLHAHDPDTMMATILDLADRA
ADEDGFLGLRAGIHHGSAVQRHHDYFGDAVNTAARVTALAGAGHAVITEPILTACEARGVAAHPLGETELRNISAPVAVY
RVQLPPPQYPTDPVCGIRLDPRTATHHLRHNDHDLWFCSDRCARRFAAHPAMDEI

Specific function: Catalyzes the formation of the second messenger cAMP [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 23128; Mature: 22997

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEAASADATFAFVDLSGFTALTEICGDEQAAHLAGRLVELTRDSLALDVTLVKAMGDAV
CCCCCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
MLHAHDPDTMMATILDLADRAADEDGFLGLRAGIHHGSAVQRHHDYFGDAVNTAARVTAL
EEEECCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGAGHAVITEPILTACEARGVAAHPLGETELRNISAPVAVYRVQLPPPQYPTDPVCGIRL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEE
DPRTATHHLRHNDHDLWFCSDRCARRFAAHPAMDEI
CCCHHHHHHCCCCCCEEEECHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GEAASADATFAFVDLSGFTALTEICGDEQAAHLAGRLVELTRDSLALDVTLVKAMGDAV
CCCCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
MLHAHDPDTMMATILDLADRAADEDGFLGLRAGIHHGSAVQRHHDYFGDAVNTAARVTAL
EEEECCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGAGHAVITEPILTACEARGVAAHPLGETELRNISAPVAVYRVQLPPPQYPTDPVCGIRL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEE
DPRTATHHLRHNDHDLWFCSDRCARRFAAHPAMDEI
CCCHHHHHHCCCCCCEEEECHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]