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The map label for this gene is traI [C]

Identifier: 119854906

GI number: 119854906

Start: 18698

End: 21538

Strand: Reverse

Name: traI [C]

Synonym: Mkms_5511

Alternate gene names: 119854906

Gene position: 21538-18698 (Counterclockwise)

Preceding gene: 119854907

Following gene: 119854905

Centisome position: 7.13

GC content: 68.74

Gene sequence:

>2841_bases
GTGCTGACGATCTCGCGGCTGAGTCGCTGGAGCATCGGCTACTACAACGACACCGCCAATCAGGCCCGGCAAGCCTCGAT
GGACCGTCAGGCCGCCGGCGGCGGCCTGGGCGAGTACTACTCCGAAGGCGACACCCGGGTCCCGACCTGGGTCGTGGTCG
GCGACAAGGCCACCGTCGGTGAGGCCACCGGACTCGACGGCGCCGCGCTCGACGGCGGGTTTGCTGACACCGAGGTAGCG
GCACGGTGGCTCGACGACGGCGTGACGCCCAACGGGGAGGCCGGACGGGCGTTCGGGACCAACGGGGTGCACGGGTTTGA
CCTGATGTTCGCCGCGCCCAAGAGTGTGTCGCTGCTGCGGTCGCTGACCGACGACGTGGCCGAAAAGGTCATGCAGAACG
CCCACGTCAAAGCAGTCGAAGCCGCGATGACCTACCTGCATGAACATGCCGGGTACACGCGGGTGCACAACCCGCTGACC
AGCAACAAAGACCTCCAGCGGCTGCCCGGGCTGGTCGCGATCGCCTACCAGCACGAGACGAGCCGCTGCGGGGACCCGCA
CCTGCACACGCACGTCATCGTGCCGAATCGCCAGGTCAGAGCTGATGGGCGGCTGGTGTCTATCGACTCCAAGTCGCTGT
ATCACGAAGCCAAAGCCGCCGGGATCATCTACCAGGCCACGCTGCGCCACGAGTTGCACGCCGAGCGGGGCTTCGAATGG
CAGCCCGTCGACGAGCATTCCGGCATGGCCGAGATCGCCGGCGTCACCGCGGCGAGCATCAAGGCGTGGTCGCAGCGTTC
GACGCGGCTGCGGGAATGGGCCAAAGACAACCTGGTCGTCGTCGACGGTGAGCCGACCGCCGCGCAGTTGGCGACCGCGC
AGAAAGCCACCCGGCCCACTAAACCCGAGCAGCTCGCCTGGGACGAACTCAAAGCGATGTGGCGCGCCGACGCGCGCGGT
CTGGATCTGGACCGCGACGCGCATTTCGCCGCGCGCGAGGCGCGGCGCGCACAGGCGCGCTCTCCCCTGGACCGAGCGCG
CATCGCGCACATGGCAGCGCGCATCGACAAGGCCGCGTTCACGCGCGCGGACATGGTGGAGATCGTCGGCGCGCAGCTGC
CCGTCGGCGCGGTCGGGGAACCGCGCGCGCTCATCGAAGCGTTCGTCGACGACGTCGGTGTGCGCATCAGCGCGCCGCGC
GAAGCGCACCACCGCGAGGGGCACGAGAAGTACACCGTCGACGCGATCATGCTCGAGGAGTCCCGCATCCTCGACATGGT
TGATACCTCCGACAACCGCAGTCGACTCGATGTGCGCGCTGCCGATCTCGGGGACCTCTCCGCCGACCAAGAGCGCGCCA
TCCGCAACATCGCCGTCTCCCCATTTCTGGTGCAGCCCTTGCAGGCTCCGGCCGGTGCTGGCAAAACTCACTCACTGAAA
GCGTTGCGCGCCGCCGCGCACCGGGCGAACAAAGAAGTGCTCGTGCTCGCGCCCACCGGCAAAGCCGTCGACGAGGCGAT
GCAGGAGGAAGCCGGCGACCGCGGCCTGACCGTGGCCAAGGCGCTCAAACTCATCGAGGACAACAATCTGGCCATCGACC
GGCGCACCGTGGTCGTCGTCGACGAAGCCTCCATGGTCGGCACCCCCGAGCTGAAAAAACTGCTGTCGGCCGCGGTGGCC
GGGCGCGCGAAGATGGTGCTCGTCGGGGACCCCTACCAGCTGGCGCCGGTGAAAGCCCGCGGCGGCATGTTCGAGCATCT
CTGCGGGGACCTGCCCTGGTCGCAGCGCCTGGGCGAAGTGTGGCGGATGCGCAGCGCCGAGGAGCGCGACGCCTCCCTGG
CGTTGCGGTCCGGGCACGGCAATCGCCTGCGCAAGGCGGTCGGCTGGTATCGCAGTCACGGCCGCCTGCACACCGGCGAC
CCGATCGCGATGGCCAAAGACGCCGGCGATGCCTACCTGGCTGACCGGGCCGCCGGGAAAGACTCACTGATGGTCTGCGA
CTCCTGGGAGATGGCCGACGCGCTCAACCAGCGCGTTCACAACGCCCTCGTCGGCGACGGGCCGTCCGTGCGGGCCGCCC
GCGACCAGCGCATCGCCGTCGGCGACATCATCATCAGCCGCGAAAACGACATCAGCATCCCCGTGCACCCCGGGGCCGAG
CACCCCGTCGGCCAGGCCGTCGACCAAGTACGTAACGGCAACCGGTGGCGCGTGGCCGGCATCGACGAGAAGACCAATCG
GGTGGCCGCCGAACGGCTCACCGACAAAGCGCGCGTCGTCTTCGACGGCGACTACCTGCGCCAGAACGTCACCCTCGGCT
ACGCGGTGACCGTGCACTCCGCCCAGGGAGTCACCGTGGGCAACAAAACCACTCCCGGTGTGTGCCACTCCATCCTGGCC
GACACCTCCAGCCGAGCCATGGCCTATGTCGGCATGACCCGCGCCAAAGACGAAAACCATGCCTACGTCTACCAACGGAT
CAGCGGCGAAGCCGACCACGAACACTCACGCCTGGTCGCCGGGGCTGACATTCACGTCCTGCGGCGCGGCAACAAATGGG
CTGCCGCCCACCACTTCCGCACCATCCTGGCCAACGACGACCGGCCCCGCACCATGCACGCCGAAGCTGAACGCACCGAA
CGTGACCTACTCCCCCAACCCGTCAGCGACCTGCTGATCGCCCAAGAGCAGCGCCGCAGCGCCCGCAGCGCGGTATGGCG
CGAACACAGCGCCGCCGGCCGGGCCGCGGCTGCGGCCTACCAGCGGATGGCCACCGTCGCCGAGACCGTCGCCGAACGCG
ACCGTGACCGGGGGCGCGACATCGACGGCCTCGAACTCTGA

Upstream 100 bases:

>100_bases
AGTTGTGCAATACTCGGCTTCGGGCGCTGGCGCGCCCGAACCCCGGCCGCCTGGCGGCGGCCTGTCCGGCTTGGTGAGGT
GGTCTGGTGGCGGCGCGACC

Downstream 100 bases:

>100_bases
TCTGCTGACGCACAGTGCCACCAACGCGCGATAGCGTCAGAACCTGACCGGTTGCTGCGGGGAGCCAGCGGCCAACGACG
CAAGGAGTGCACCAGGTGAA

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 946; Mature: 946

Protein sequence:

>946_residues
MLTISRLSRWSIGYYNDTANQARQASMDRQAAGGGLGEYYSEGDTRVPTWVVVGDKATVGEATGLDGAALDGGFADTEVA
ARWLDDGVTPNGEAGRAFGTNGVHGFDLMFAAPKSVSLLRSLTDDVAEKVMQNAHVKAVEAAMTYLHEHAGYTRVHNPLT
SNKDLQRLPGLVAIAYQHETSRCGDPHLHTHVIVPNRQVRADGRLVSIDSKSLYHEAKAAGIIYQATLRHELHAERGFEW
QPVDEHSGMAEIAGVTAASIKAWSQRSTRLREWAKDNLVVVDGEPTAAQLATAQKATRPTKPEQLAWDELKAMWRADARG
LDLDRDAHFAAREARRAQARSPLDRARIAHMAARIDKAAFTRADMVEIVGAQLPVGAVGEPRALIEAFVDDVGVRISAPR
EAHHREGHEKYTVDAIMLEESRILDMVDTSDNRSRLDVRAADLGDLSADQERAIRNIAVSPFLVQPLQAPAGAGKTHSLK
ALRAAAHRANKEVLVLAPTGKAVDEAMQEEAGDRGLTVAKALKLIEDNNLAIDRRTVVVVDEASMVGTPELKKLLSAAVA
GRAKMVLVGDPYQLAPVKARGGMFEHLCGDLPWSQRLGEVWRMRSAEERDASLALRSGHGNRLRKAVGWYRSHGRLHTGD
PIAMAKDAGDAYLADRAAGKDSLMVCDSWEMADALNQRVHNALVGDGPSVRAARDQRIAVGDIIISRENDISIPVHPGAE
HPVGQAVDQVRNGNRWRVAGIDEKTNRVAAERLTDKARVVFDGDYLRQNVTLGYAVTVHSAQGVTVGNKTTPGVCHSILA
DTSSRAMAYVGMTRAKDENHAYVYQRISGEADHEHSRLVAGADIHVLRRGNKWAAAHHFRTILANDDRPRTMHAEAERTE
RDLLPQPVSDLLIAQEQRRSARSAVWREHSAAGRAAAAAYQRMATVAETVAERDRDRGRDIDGLEL

Sequences:

>Translated_946_residues
MLTISRLSRWSIGYYNDTANQARQASMDRQAAGGGLGEYYSEGDTRVPTWVVVGDKATVGEATGLDGAALDGGFADTEVA
ARWLDDGVTPNGEAGRAFGTNGVHGFDLMFAAPKSVSLLRSLTDDVAEKVMQNAHVKAVEAAMTYLHEHAGYTRVHNPLT
SNKDLQRLPGLVAIAYQHETSRCGDPHLHTHVIVPNRQVRADGRLVSIDSKSLYHEAKAAGIIYQATLRHELHAERGFEW
QPVDEHSGMAEIAGVTAASIKAWSQRSTRLREWAKDNLVVVDGEPTAAQLATAQKATRPTKPEQLAWDELKAMWRADARG
LDLDRDAHFAAREARRAQARSPLDRARIAHMAARIDKAAFTRADMVEIVGAQLPVGAVGEPRALIEAFVDDVGVRISAPR
EAHHREGHEKYTVDAIMLEESRILDMVDTSDNRSRLDVRAADLGDLSADQERAIRNIAVSPFLVQPLQAPAGAGKTHSLK
ALRAAAHRANKEVLVLAPTGKAVDEAMQEEAGDRGLTVAKALKLIEDNNLAIDRRTVVVVDEASMVGTPELKKLLSAAVA
GRAKMVLVGDPYQLAPVKARGGMFEHLCGDLPWSQRLGEVWRMRSAEERDASLALRSGHGNRLRKAVGWYRSHGRLHTGD
PIAMAKDAGDAYLADRAAGKDSLMVCDSWEMADALNQRVHNALVGDGPSVRAARDQRIAVGDIIISRENDISIPVHPGAE
HPVGQAVDQVRNGNRWRVAGIDEKTNRVAAERLTDKARVVFDGDYLRQNVTLGYAVTVHSAQGVTVGNKTTPGVCHSILA
DTSSRAMAYVGMTRAKDENHAYVYQRISGEADHEHSRLVAGADIHVLRRGNKWAAAHHFRTILANDDRPRTMHAEAERTE
RDLLPQPVSDLLIAQEQRRSARSAVWREHSAAGRAAAAAYQRMATVAETVAERDRDRGRDIDGLEL
>Mature_946_residues
MLTISRLSRWSIGYYNDTANQARQASMDRQAAGGGLGEYYSEGDTRVPTWVVVGDKATVGEATGLDGAALDGGFADTEVA
ARWLDDGVTPNGEAGRAFGTNGVHGFDLMFAAPKSVSLLRSLTDDVAEKVMQNAHVKAVEAAMTYLHEHAGYTRVHNPLT
SNKDLQRLPGLVAIAYQHETSRCGDPHLHTHVIVPNRQVRADGRLVSIDSKSLYHEAKAAGIIYQATLRHELHAERGFEW
QPVDEHSGMAEIAGVTAASIKAWSQRSTRLREWAKDNLVVVDGEPTAAQLATAQKATRPTKPEQLAWDELKAMWRADARG
LDLDRDAHFAAREARRAQARSPLDRARIAHMAARIDKAAFTRADMVEIVGAQLPVGAVGEPRALIEAFVDDVGVRISAPR
EAHHREGHEKYTVDAIMLEESRILDMVDTSDNRSRLDVRAADLGDLSADQERAIRNIAVSPFLVQPLQAPAGAGKTHSLK
ALRAAAHRANKEVLVLAPTGKAVDEAMQEEAGDRGLTVAKALKLIEDNNLAIDRRTVVVVDEASMVGTPELKKLLSAAVA
GRAKMVLVGDPYQLAPVKARGGMFEHLCGDLPWSQRLGEVWRMRSAEERDASLALRSGHGNRLRKAVGWYRSHGRLHTGD
PIAMAKDAGDAYLADRAAGKDSLMVCDSWEMADALNQRVHNALVGDGPSVRAARDQRIAVGDIIISRENDISIPVHPGAE
HPVGQAVDQVRNGNRWRVAGIDEKTNRVAAERLTDKARVVFDGDYLRQNVTLGYAVTVHSAQGVTVGNKTTPGVCHSILA
DTSSRAMAYVGMTRAKDENHAYVYQRISGEADHEHSRLVAGADIHVLRRGNKWAAAHHFRTILANDDRPRTMHAEAERTE
RDLLPQPVSDLLIAQEQRRSARSAVWREHSAAGRAAAAAYQRMATVAETVAERDRDRGRDIDGLEL

Specific function: traI Has Been Identified As DNA Helicase I And It Also Has An Additional Activity Of Site-Specific Nicking At Orit. DNA Helicase I Is A Potent DNA-Dependent ATPase. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 103243; Mature: 103243

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00018 EF_HAND_1 ; PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTISRLSRWSIGYYNDTANQARQASMDRQAAGGGLGEYYSEGDTRVPTWVVVGDKATVG
CCCHHHHCCCCCCEECCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEEEECCCCCCC
EATGLDGAALDGGFADTEVAARWLDDGVTPNGEAGRAFGTNGVHGFDLMFAAPKSVSLLR
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHH
SLTDDVAEKVMQNAHVKAVEAAMTYLHEHAGYTRVHNPLTSNKDLQRLPGLVAIAYQHET
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHCCCEEEEEEECCC
SRCGDPHLHTHVIVPNRQVRADGRLVSIDSKSLYHEAKAAGIIYQATLRHELHAERGFEW
CCCCCCCCEEEEEECCCEEECCCCEEEECCHHHHHHHHHCCEEEHHHHHHHHHHHCCCCC
QPVDEHSGMAEIAGVTAASIKAWSQRSTRLREWAKDNLVVVDGEPTAAQLATAQKATRPT
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCC
KPEQLAWDELKAMWRADARGLDLDRDAHFAAREARRAQARSPLDRARIAHMAARIDKAAF
CCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TRADMVEIVGAQLPVGAVGEPRALIEAFVDDVGVRISAPREAHHREGHEKYTVDAIMLEE
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEECCHHHHHCCCCCEEEEEEEEECC
SRILDMVDTSDNRSRLDVRAADLGDLSADQERAIRNIAVSPFLVQPLQAPAGAGKTHSLK
CHHEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHHH
ALRAAAHRANKEVLVLAPTGKAVDEAMQEEAGDRGLTVAKALKLIEDNNLAIDRRTVVVV
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECEEEEEE
DEASMVGTPELKKLLSAAVAGRAKMVLVGDPYQLAPVKARGGMFEHLCGDLPWSQRLGEV
ECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCEECEEHHCCCHHHHHHCCCCHHHHHHHH
WRMRSAEERDASLALRSGHGNRLRKAVGWYRSHGRLHTGDPIAMAKDAGDAYLADRAAGK
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEECCCCCEEECCCCCHHHHHHCCCC
DSLMVCDSWEMADALNQRVHNALVGDGPSVRAARDQRIAVGDIIISRENDISIPVHPGAE
CCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCEEEECCCCCC
HPVGQAVDQVRNGNRWRVAGIDEKTNRVAAERLTDKARVVFDGDYLRQNVTLGYAVTVHS
CCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHCCEEEEEEEEEC
AQGVTVGNKTTPGVCHSILADTSSRAMAYVGMTRAKDENHAYVYQRISGEADHEHSRLVA
CCCEEECCCCCHHHHHHHHHCCCCCEEEEEECHHCCCCCCEEEEEECCCCCCCCCCEEEE
GADIHVLRRGNKWAAAHHFRTILANDDRPRTMHAEAERTERDLLPQPVSDLLIAQEQRRS
CCCEEEEECCCCCHHHHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
ARSAVWREHSAAGRAAAAAYQRMATVAETVAERDRDRGRDIDGLEL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLTISRLSRWSIGYYNDTANQARQASMDRQAAGGGLGEYYSEGDTRVPTWVVVGDKATVG
CCCHHHHCCCCCCEECCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEEEECCCCCCC
EATGLDGAALDGGFADTEVAARWLDDGVTPNGEAGRAFGTNGVHGFDLMFAAPKSVSLLR
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHH
SLTDDVAEKVMQNAHVKAVEAAMTYLHEHAGYTRVHNPLTSNKDLQRLPGLVAIAYQHET
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHCCCEEEEEEECCC
SRCGDPHLHTHVIVPNRQVRADGRLVSIDSKSLYHEAKAAGIIYQATLRHELHAERGFEW
CCCCCCCCEEEEEECCCEEECCCCEEEECCHHHHHHHHHCCEEEHHHHHHHHHHHCCCCC
QPVDEHSGMAEIAGVTAASIKAWSQRSTRLREWAKDNLVVVDGEPTAAQLATAQKATRPT
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCC
KPEQLAWDELKAMWRADARGLDLDRDAHFAAREARRAQARSPLDRARIAHMAARIDKAAF
CCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TRADMVEIVGAQLPVGAVGEPRALIEAFVDDVGVRISAPREAHHREGHEKYTVDAIMLEE
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEECCHHHHHCCCCCEEEEEEEEECC
SRILDMVDTSDNRSRLDVRAADLGDLSADQERAIRNIAVSPFLVQPLQAPAGAGKTHSLK
CHHEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHHH
ALRAAAHRANKEVLVLAPTGKAVDEAMQEEAGDRGLTVAKALKLIEDNNLAIDRRTVVVV
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECEEEEEE
DEASMVGTPELKKLLSAAVAGRAKMVLVGDPYQLAPVKARGGMFEHLCGDLPWSQRLGEV
ECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCEECEEHHCCCHHHHHHCCCCHHHHHHHH
WRMRSAEERDASLALRSGHGNRLRKAVGWYRSHGRLHTGDPIAMAKDAGDAYLADRAAGK
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEECCCCCEEECCCCCHHHHHHCCCC
DSLMVCDSWEMADALNQRVHNALVGDGPSVRAARDQRIAVGDIIISRENDISIPVHPGAE
CCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCEEEECCCCCC
HPVGQAVDQVRNGNRWRVAGIDEKTNRVAAERLTDKARVVFDGDYLRQNVTLGYAVTVHS
CCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHCCEEEEEEEEEC
AQGVTVGNKTTPGVCHSILADTSSRAMAYVGMTRAKDENHAYVYQRISGEADHEHSRLVA
CCCEEECCCCCHHHHHHHHHCCCCCEEEEEECHHCCCCCCEEEEEECCCCCCCCCCEEEE
GADIHVLRRGNKWAAAHHFRTILANDDRPRTMHAEAERTERDLLPQPVSDLLIAQEQRRS
CCCEEEEECCCCCHHHHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
ARSAVWREHSAAGRAAAAAYQRMATVAETVAERDRDRGRDIDGLEL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]