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The map label for this gene is rlmM [H]

Identifier: 228906474

GI number: 228906474

Start: 1085393

End: 1086454

Strand: Reverse

Name: rlmM [H]

Synonym: azo1009

Alternate gene names: 228906474

Gene position: 1086454-1085393 (Counterclockwise)

Preceding gene: 119897302

Following gene: 119897299

Centisome position: 24.83

GC content: 69.11

Gene sequence:

>1062_bases
GTGTCCGGCCTGCTCGCCTACTGCCGCGCCGGCTTCGAAAAGGAACTCGCTGCGGAGATCGACGACCTCGCCGCCGACGC
CGGCCTGATCGGCTATGTGCGCACCGAGCCGGGCAGCGGCTACGCCGCGTTCGAGACCTTCGAACCGGTGCCGGTGATCA
AGCTCGGCGAATTCGCCGACTGGCGCAAGCCGGTGTTCGCCCGCCAGCTGCTGCCCTGGTTCGACCGCATCGACGACCTG
CCCGAACGCGACCGGGCGCGCCCCCTGGTGGATATGGTCAAGGGCTCCGGCCAGCGTTTTTCCGGGGTTGTGCTCGAAAC
CCCGGACACCGACGAGGCCAAGCAACGCTCCGGCTTCTGCCGCCGCTTCACCGAACCGCTCACGCGCGAACTCGAAAAGG
TGGGCGCGCTGCGGCTCGGCAAGCCGGGCTTCCCGGTGCTGCACGTGATGTTTCCCACCGCCACCAGCGCCTGGCTCGCC
GCCGGCCTCAAGGACCGCTGCGCGCCGTGGCCGATGGGCATTCCGCGCCTGCGCATGCCCTCCAACGCCCCCAGCCGGTC
CACGCTGAAGCTCGCCGAGGCCATCATGACCCTGCTCAGCGACGAGGAACGCGATTCCCTGCTGCGCGCCGGCATGCGCG
CGGTCGACCTCGGCGCCGCGCCCGGCGGCTGGACCTGGCAGCTCGCCCAGCGCGGCATCCGCGTCACCGCGATCGACAAC
GGGCCGCTGCGCGACACCGTGATGGCCACCGAGATGGTCGAACACCTCAAGGCCGACGGCTTCACCTGGCGGCCACAGCG
TCCGGTGGACTGGATGGTATGCGACATGGTCGAGCAACCCAGCCGCATCGCCTCGCTGATGGCCGAATGGATCGCCACCG
GGCGCTGCCGCCACACCATCTTCAATCTCAAGCTGCCGATGAAGCGGCGCCTCGAGGCGGTCGAGCAGTGCCGCGAACTC
ATCCGCAAGCGGCTCGCCAGCATCGGCCCCTTCGACCTGCGCATCAAGCAGCTCTACCACGACCGCGAGGAAGTCACCGC
CTATCTCACCCTGAAGAAGTGA

Upstream 100 bases:

>100_bases
GTGGCGCGGCACCTTATGATGCGCCGCTTCGCAGCATGATACTGCAGCACGCCCAAGGCCCCGCCCGATGTCCTCCCACG
CCCCCGCCTCCAGCTTTTCC

Downstream 100 bases:

>100_bases
GCCCCGCGGCGGGGAAAGCCGTCGGAAGCACTTGTCACGAAACGATTTTCGGCGCACGTGTATAATCGCTGCTTTCCATG
CACCCGGCCTGCCGGCTGGC

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSGLLAYCRAGFEKELAAEIDDLAADAGLIGYVRTEPGSGYAAFETFEPVPVIKLGEFADWRKPVFARQLLPWFDRIDDL
PERDRARPLVDMVKGSGQRFSGVVLETPDTDEAKQRSGFCRRFTEPLTRELEKVGALRLGKPGFPVLHVMFPTATSAWLA
AGLKDRCAPWPMGIPRLRMPSNAPSRSTLKLAEAIMTLLSDEERDSLLRAGMRAVDLGAAPGGWTWQLAQRGIRVTAIDN
GPLRDTVMATEMVEHLKADGFTWRPQRPVDWMVCDMVEQPSRIASLMAEWIATGRCRHTIFNLKLPMKRRLEAVEQCREL
IRKRLASIGPFDLRIKQLYHDREEVTAYLTLKK

Sequences:

>Translated_353_residues
MSGLLAYCRAGFEKELAAEIDDLAADAGLIGYVRTEPGSGYAAFETFEPVPVIKLGEFADWRKPVFARQLLPWFDRIDDL
PERDRARPLVDMVKGSGQRFSGVVLETPDTDEAKQRSGFCRRFTEPLTRELEKVGALRLGKPGFPVLHVMFPTATSAWLA
AGLKDRCAPWPMGIPRLRMPSNAPSRSTLKLAEAIMTLLSDEERDSLLRAGMRAVDLGAAPGGWTWQLAQRGIRVTAIDN
GPLRDTVMATEMVEHLKADGFTWRPQRPVDWMVCDMVEQPSRIASLMAEWIATGRCRHTIFNLKLPMKRRLEAVEQCREL
IRKRLASIGPFDLRIKQLYHDREEVTAYLTLKK
>Mature_352_residues
SGLLAYCRAGFEKELAAEIDDLAADAGLIGYVRTEPGSGYAAFETFEPVPVIKLGEFADWRKPVFARQLLPWFDRIDDLP
ERDRARPLVDMVKGSGQRFSGVVLETPDTDEAKQRSGFCRRFTEPLTRELEKVGALRLGKPGFPVLHVMFPTATSAWLAA
GLKDRCAPWPMGIPRLRMPSNAPSRSTLKLAEAIMTLLSDEERDSLLRAGMRAVDLGAAPGGWTWQLAQRGIRVTAIDNG
PLRDTVMATEMVEHLKADGFTWRPQRPVDWMVCDMVEQPSRIASLMAEWIATGRCRHTIFNLKLPMKRRLEAVEQCRELI
RKRLASIGPFDLRIKQLYHDREEVTAYLTLKK

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=352, Percent_Identity=42.8977272727273, Blast_Score=288, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 39809; Mature: 39677

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLLAYCRAGFEKELAAEIDDLAADAGLIGYVRTEPGSGYAAFETFEPVPVIKLGEFAD
CCCHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEECCCCCCCCCEEECCCHH
WRKPVFARQLLPWFDRIDDLPERDRARPLVDMVKGSGQRFSGVVLETPDTDEAKQRSGFC
HHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHCCCCEECCEEEECCCCHHHHHHHHHH
RRFTEPLTRELEKVGALRLGKPGFPVLHVMFPTATSAWLAAGLKDRCAPWPMGIPRLRMP
HHHHHHHHHHHHHHCCHHCCCCCCCEEEEECCCHHHHHHHHCHHHHCCCCCCCCCCCCCC
SNAPSRSTLKLAEAIMTLLSDEERDSLLRAGMRAVDLGAAPGGWTWQLAQRGIRVTAIDN
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHEECCCCCCCCCHHHHHCCEEEEEECC
GPLRDTVMATEMVEHLKADGFTWRPQRPVDWMVCDMVEQPSRIASLMAEWIATGRCRHTI
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHH
FNLKLPMKRRLEAVEQCRELIRKRLASIGPFDLRIKQLYHDREEVTAYLTLKK
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHEEEEEEECC
>Mature Secondary Structure 
SGLLAYCRAGFEKELAAEIDDLAADAGLIGYVRTEPGSGYAAFETFEPVPVIKLGEFAD
CCHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEECCCCCCCCCEEECCCHH
WRKPVFARQLLPWFDRIDDLPERDRARPLVDMVKGSGQRFSGVVLETPDTDEAKQRSGFC
HHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHCCCCEECCEEEECCCCHHHHHHHHHH
RRFTEPLTRELEKVGALRLGKPGFPVLHVMFPTATSAWLAAGLKDRCAPWPMGIPRLRMP
HHHHHHHHHHHHHHCCHHCCCCCCCEEEEECCCHHHHHHHHCHHHHCCCCCCCCCCCCCC
SNAPSRSTLKLAEAIMTLLSDEERDSLLRAGMRAVDLGAAPGGWTWQLAQRGIRVTAIDN
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHEECCCCCCCCCHHHHHCCEEEEEECC
GPLRDTVMATEMVEHLKADGFTWRPQRPVDWMVCDMVEQPSRIASLMAEWIATGRCRHTI
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHH
FNLKLPMKRRLEAVEQCRELIRKRLASIGPFDLRIKQLYHDREEVTAYLTLKK
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA