Click here to switch to the map view.

The map label for this gene is waaE2 [H]

Identifier: 119899852

GI number: 119899852

Start: 3909437

End: 3910396

Strand: Direct

Name: waaE2 [H]

Synonym: azo3563

Alternate gene names: 119899852

Gene position: 3909437-3910396 (Clockwise)

Preceding gene: 119899851

Following gene: 119899853

Centisome position: 89.34

GC content: 73.02

Gene sequence:

>960_bases
ATGTCCCAACCGCTGCCTTCCTCCCTGCCCGACTTCACCCGCGGCCGCGTTCTCGTCGTCGGCGACGTGATGCTCGACCG
CTACTGGCATGGCTCCACCACGCGCATCTCGCCCGAGGCCCCGGTGCCGGTGGTGAAGGTGGAAGGCGACGAATTCCGCG
CCGGCGGCGCCGGCAACGTCGCGCTCAACGCCGCCTCGCTGGGCGCCGGCGCCGAGCTGGTCGGGCTGGTCGGGCGTGAC
GAAGCCGCCCGCCTGCTGCGCGAACGGCTGCAAGCCGGCGGCGTGGTGTGTCGCCTGGAAGAAGCGCCGCAACACCCCAC
GATCACCAAGCTGCGCATCATCAGCCGCCACCAGCAGCTGATCCGGCTCGACTTCGAGGACAACTTCGCGGTGCTGGAAT
CGGCCGGCATCGAAGCCGCGTTCGAAGCGGCGCTGCCGGGCAGCGGCGCGGTCGTGCTCTCCGACTACGGCAAGGGCACG
CTGGCCGGCGTCGGCACGCTGGTCCGGGTCGCACGCGAACGCGGGCTGCCGGTGGTGGTCGACCCCAAGGGCACCGATTT
CGCGCGCTACCGCGGCGCCACCGTGATCACCCCCAATCTCGCCGAGTTCGAGGCGGTGGTGGGCCACTGCGCAGACGAAG
CCACGCTGGTCTCGCGCGGCGAGGCGCTGCGCGACACGCTGGACCTCGACGCGCTGCTGGTCACCCGCTCCGAGCGCGGC
ATGACGCTGCTCGAACGCGGCCACGCCCCGCTCAACCTGCCGACGCGCGCGCGCGACGTGTTCGACGTGACCGGCGCGGG
CGACACCGTGGTCGCAGTGCTCGGCGCCGGCCTCGCCTGCGGGCTGACGCTGGCCGAAGCCACCGCGCTCGCCAACCTCG
CGGCCGGCGTCGTGGTCGGCAAGCTGGGCACCGCCACGGTCAGCGCCGTCGAACTCGCCGATGCCCTGCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCCGGCACCGCAGGCCCCGGGCGACCGCGTTCGCCGCGCCGCCGGAGCGGCCTTCGTGGGATAATTGCGGACTTTTCAA
CACGCTAGCGCGCCTTGCCG

Downstream 100 bases:

>100_bases
GGCGCCCGCGGCCCCCAGACGTACTGAAAGAGGAAAACCGAGATGATCATCGTTACCGGCGGCGCCGGCTTCATCGGCAG
CAACATCGTGCAGGGCCTCA

Product: ADP-heptose synthase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSQPLPSSLPDFTRGRVLVVGDVMLDRYWHGSTTRISPEAPVPVVKVEGDEFRAGGAGNVALNAASLGAGAELVGLVGRD
EAARLLRERLQAGGVVCRLEEAPQHPTITKLRIISRHQQLIRLDFEDNFAVLESAGIEAAFEAALPGSGAVVLSDYGKGT
LAGVGTLVRVARERGLPVVVDPKGTDFARYRGATVITPNLAEFEAVVGHCADEATLVSRGEALRDTLDLDALLVTRSERG
MTLLERGHAPLNLPTRARDVFDVTGAGDTVVAVLGAGLACGLTLAEATALANLAAGVVVGKLGTATVSAVELADALRAA

Sequences:

>Translated_319_residues
MSQPLPSSLPDFTRGRVLVVGDVMLDRYWHGSTTRISPEAPVPVVKVEGDEFRAGGAGNVALNAASLGAGAELVGLVGRD
EAARLLRERLQAGGVVCRLEEAPQHPTITKLRIISRHQQLIRLDFEDNFAVLESAGIEAAFEAALPGSGAVVLSDYGKGT
LAGVGTLVRVARERGLPVVVDPKGTDFARYRGATVITPNLAEFEAVVGHCADEATLVSRGEALRDTLDLDALLVTRSERG
MTLLERGHAPLNLPTRARDVFDVTGAGDTVVAVLGAGLACGLTLAEATALANLAAGVVVGKLGTATVSAVELADALRAA
>Mature_318_residues
SQPLPSSLPDFTRGRVLVVGDVMLDRYWHGSTTRISPEAPVPVVKVEGDEFRAGGAGNVALNAASLGAGAELVGLVGRDE
AARLLRERLQAGGVVCRLEEAPQHPTITKLRIISRHQQLIRLDFEDNFAVLESAGIEAAFEAALPGSGAVVLSDYGKGTL
AGVGTLVRVARERGLPVVVDPKGTDFARYRGATVITPNLAEFEAVVGHCADEATLVSRGEALRDTLDLDALLVTRSERGM
TLLERGHAPLNLPTRARDVFDVTGAGDTVVAVLGAGLACGLTLAEATALANLAAGVVVGKLGTATVSAVELADALRAA

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=310, Percent_Identity=60.6451612903226, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 33122; Mature: 32991

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPLPSSLPDFTRGRVLVVGDVMLDRYWHGSTTRISPEAPVPVVKVEGDEFRAGGAGNV
CCCCCCCCCCCCCCCCEEEEEHHHHHHEECCCCCEECCCCCCCEEEECCCEECCCCCCCE
ALNAASLGAGAELVGLVGRDEAARLLRERLQAGGVVCRLEEAPQHPTITKLRIISRHQQL
EEEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCCEE
IRLDFEDNFAVLESAGIEAAFEAALPGSGAVVLSDYGKGTLAGVGTLVRVARERGLPVVV
EEEECCCCEEEEECCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEE
DPKGTDFARYRGATVITPNLAEFEAVVGHCADEATLVSRGEALRDTLDLDALLVTRSERG
CCCCCCHHHHCCCEEECCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHCCEEEEEECCCCC
MTLLERGHAPLNLPTRARDVFDVTGAGDTVVAVLGAGLACGLTLAEATALANLAAGVVVG
CCHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEE
KLGTATVSAVELADALRAA
CCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQPLPSSLPDFTRGRVLVVGDVMLDRYWHGSTTRISPEAPVPVVKVEGDEFRAGGAGNV
CCCCCCCCCCCCCCCEEEEEHHHHHHEECCCCCEECCCCCCCEEEECCCEECCCCCCCE
ALNAASLGAGAELVGLVGRDEAARLLRERLQAGGVVCRLEEAPQHPTITKLRIISRHQQL
EEEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCCEE
IRLDFEDNFAVLESAGIEAAFEAALPGSGAVVLSDYGKGTLAGVGTLVRVARERGLPVVV
EEEECCCCEEEEECCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEE
DPKGTDFARYRGATVITPNLAEFEAVVGHCADEATLVSRGEALRDTLDLDALLVTRSERG
CCCCCCHHHHCCCEEECCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHCCEEEEEECCCCC
MTLLERGHAPLNLPTRARDVFDVTGAGDTVVAVLGAGLACGLTLAEATALANLAAGVVVG
CCHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEE
KLGTATVSAVELADALRAA
CCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA