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The map label for this gene is rpoC [H]

Identifier: 119899712

GI number: 119899712

Start: 3747393

End: 3751607

Strand: Reverse

Name: rpoC [H]

Synonym: azo3423

Alternate gene names: 119899712

Gene position: 3751607-3747393 (Counterclockwise)

Preceding gene: 119899713

Following gene: 119899711

Centisome position: 85.73

GC content: 64.56

Gene sequence:

>4215_bases
ATGAAGAGCCTGCTCGCTGACCTGTTCAAGCAAACCCTGCCGAACGAGGAAGAGTTCGACGCGATCACCATCGGTCTCGC
GTCGCCGGACAAGATCCGCTCGTGGTCCTACGGTGAGGTGAAGAAGCCCGAGACCATCAACTACCGTACCTTCAAGCCGG
AACGCGACGGCCTGTTCTGCGCCAAGATTTTCGGCCCGGTGAAGGATTACGAGTGCCTGTGCGGCAAGTACAAGCGCCTC
AAGCACCGTGGTGTGATCTGCGAGAAGTGCGGCGTCGAGGTGACCCTCTCCAAGGTGCGCCGCGAGCGCATGGGTCACAT
CGAACTGGCCAGCCCGGTTGCCCACATCTGGTTCCTGAAGAGCCTGCCGAGCCGCCTCGGCATGGTGCTCGACATGACCC
TGCGCGACATCGAGCGCGTGCTGTACTTCGAAGCCTTCGTCGTGGTTGAGCCGGGCATGACCCCGCTCAACCGCGCCCAG
CTGCTCACCGAAGACGACTACCTCGCCAAGGTCGAGGAATACGGCGACGACTTCGACGCCGTGATGGGTGCCGAGGGCAT
CCGCGAGCTGCTGCGCACGCTCGACGTGAACCAGGAGATCGAACGCCTGCGTTCCGACCTGGAGACGACCGGTTCCGAAG
CCAAGATCAAGAAGTTCTCCAAGCGCCTGAAGGTGCTTGAGGCCTTCCAGCAATCCGGCATCAAGCCGGAATGGATGATC
CTGGAAGTGCTGCCGGTGCTGCCGCCGGATCTGCGCCCGCTGGTGCCGCTGGATGGTGGCCGCTTCGCGACGTCCGACCT
GAACGACCTCTACCGCCGCGTCATCAACCGCAACAACCGCCTGAAGCGCCTGCTCGAACTGAAGGCGCCGGACATCATCG
TCCGCAACGAAAAGCGCATGCTGCAGGAGTCGGTGGACTCCCTGCTCGACAACGGCCGCCGCGGCAAGGCGATGACCGGC
GCCAACAAGCGTCCGCTGAAGTCGCTGGCCGACATGATCAAGGGCAAGGGCGGCCGCTTCCGCCAGAACCTGCTCGGCAA
GCGGGTGGACTACTCGGGTCGTTCCGTGATTACCGTGGGCCCGCAGCTCAAGCTGCACCAGTGCGGTCTGCCCAAGCTGA
TGGCGCTCGAGCTGTTCAAGCCCTTCATCTTCAACAAGCTCGAACTGATGGGGCTGGCGACGACCATCAAGCAGGCCAAG
AAGATGGTGGAGTCGCAGGAGCCGGTGGTGTGGGACATCCTCGAAGATGTCATCCGCGAACACCCGGTGATGCTGAACCG
CGCGCCCACGCTGCACCGTCTCGGCATCCAGGCTTTTGAGCCGGTGCTGATCGAAGGCAAGGCGATCCAGCTGCATCCGC
TGGTCTGCGTGGCGTTCAACGCCGACTTCGACGGTGACCAGATGGCCGTCCACGTGCCGCTGTCGCTGGAAGCGCAAATG
GAAGCGCGCACGCTGATGCTGGCCTCCAACAACGTGCTGTCGCCCGCCAACGGCGACCCGATCATCGTTCCGTCGCAGGA
CATCGTGCTCGGCCTGTACTACGCGACCCGCGAAGGCGTGAACGTGCCGGGCGAAGGCATGCTGTTTACCGACGTGGGTG
AAGTGAAGCGCGCCTACGAGTCGGGTCAGATCTCGCTGCACGCCCGCGTGACGGTGCGTCTGAAGGAGTTCGACCGCGGT
CCGGAGGGTGAGCGCATCGAGCGCGTGGTGCGTCACAACACCACCGCCGGCCGTGCCATCCTGTCGGAGATTCTGCCGGC
AGGCCTGCCCTTCAGCGTGATCGACAAGCCGCTGAAGAAGAAGGAAATCTCGAAGCTGATCAACGCGTCGTTCCGCCGCT
GCGGCCTGCGCGCGACGGTGATCTTCGCCGATCAGCTGATGCAATACGGCTACCGTCTCGCCACCCGCGCCGGTATCTCG
ATCGCGGTCAAGGACATGCTGGTGCCGGATCTGAAGGAAGACCTGATCCGCGCCGCCGAAGCCGAAGTCAAGGAAATCGC
CCAGCAGTACACGTCGGGTCTGGTGACCGACGGCGAGCGCTACAACAAGGTCGTGGATATCTGGGGTCGCTGCGGCGACC
AGGTGGCCAAGGCGATGATGGAGCAGCTCGGCCAGGAGCCGGTGGTCGACCGCAACGGCAATACCGTTAAGCAGGAAGCG
TTCAACTCCATCTACATGATGGCCGACTCCGGTGCCCGTGGTTCGGCGGCGCAGATCCGTCAGCTGGCCGGCATGCGCGG
CCTGATGGCGAAGCCGGACGGCTCGATCATCGAGACGCCGATCACGACCAACTTCCGCGAAGGCCTGAACGTTCTGCAGT
ACTTCATCTCGACCCACGGCGCCCGTAAGGGTCTGGCGGATACCGCGCTGAAGACCGCGAACTCCGGCTACCTCACTCGC
CGCCTGGTCGACGTGACGCAGGATCTGGTCGTCATCGAAGACGATTGCGGCACGCGCGAAGGCTTCAACATGAAGGCCCT
GATCGAGGGCGGTGAAGTCGTCGAACCGCTGCGCGAACGCATCCTCGGCCGCGTCTGCGCCGAGGACGTGGTCAATCCGG
ATACCCAGGAAACCGCCATCGAGGCCGGCACCCTGCTCGACGAGGACATGGTCGACCTGATCGAAAGCCTCGGCGTCGAT
GAGGTCAAGGTCCGCACCCCGCTGACCTGCGAAACGCGCTACGGCCTGTGCGCCAAGTGCTATGGCCGCGACCTCGGCCG
CGGCGCGATGGTCAATGCCGGCGAGGCCGTCGGCGTCATCGCGGCCCAGTCGATCGGCGAGCCGGGCACGCAGCTGACCA
TGCGTACCTTCCACGTCGGTGGCGCGGCCTCCCGGGCGGCTGCGGCGAGCGGTGTCGAAGCCAAGTCGAGCGGTACGATC
CGTTTCGCCGGCAACATGCGCTACGTGGCCAACGCCAAGGGCGAGAAGGTCGTCATTGCACGTTCCGCCGAAGTGGTGGT
GGCCGACGACATGGGCCGCGAGCGTGAGCGTCACAAGCTGCCGTACGGCGCGATGCTGCTGGTCGATGACGGCGCCCAGG
TCAAGGCCGGCGCCCAACTGGCCTCGTGGGATCCGCACACCCGCCCGATCGTCACCGAGTACTCCGGTACGGTGAAGTTC
GAGAACGTCGAAGAAGGCGTGACGGTTGCGAAGCAGATCGACGAGGTCACCGGCCTGTCGACGCTCGTGGTCATCGATTC
GAAGCGTCGCTCCAGCTCCGGCGCCGCCAAGGGCGTGCGTCCGCAGGTGAAGCTGCTGGACGAGAACGGCGAAGAGGTGC
GGATCGCCGGCACCGACCACGCGGTCGCGATCACCTTCCAGGTCGGCTCGCTGATCACCGTGAAGGACGGCCAGCAGGTC
AGCGTCGGCGACATCCTGGCCCGTATCCCGCAGGAATCGGCGAAGACGCGCGACATTACCGGCGGTCTGCCGCGTGTGGC
GGAACTGTTCGAAGCGCGTTCGCCGAAGGACGCCGGCCTGCTGGCCGAGTACACCGGTACGGTTTCGTTCGGCAAGGACA
CCAAGGGCAAGCAGCGTCTCGTGATCACCGAGCCGGACGGCACGGTGCACGAGTTCCTGATCCCGAAGGACAAGCACCTG
ATGGTCCACGACGGCCAGGTGGTGAACAAGGGCGAGCTGATCGTCGACGGTCCTGCGGATCCGCACGACATCCTGCGTCT
GCAGGGCATCAACGAACTTGCGCGCTACATCATCGACGAGGTGCAGGACGTCTATCGTCTGCAGGGCGTGAAGATCAACG
ACAAGCACATCGAGGTGATCGTCCGCCAGATGCTGCGTCGCGTCGTCATCACCGATCCGGGCGATACCAAGTTCATCCGC
GAGGAGCAGGTCGAGCGCTCGGAAGTGCTGGACGAGAACGATCGCATCGAGGCGGAAGGCAAGCTGCCGGCGCAGTACGA
AAACGTGCTGCTGGGTATTACCAAGGCGTCGCTGTCCACCGACTCGTTCATCTCGGCGGCCTCGTTCCAGGAAACCACCC
GCGTGCTGACCGAAGCGGCGATCATGGGCAAGCGCGACGAACTGCGTGGCCTGAAGGAGAACGTCATCGTCGGTCGCCTG
ATCCCCGCCGGTACCGGCCTGGCCTACCACCGCAGCCGTCGCTCGCAGTCGGCCGGAGAGGACCTCGGCATCGAGCACGC
GTGGGCGCCGATCGAAACGCCCGCCGAGGAGCAGCACGACATTTCCGCGAGTTGA

Upstream 100 bases:

>100_bases
TCGACATCGATCTCGACCGCGAGTGACCCGGAAGCCAAACCTGCCTGCGATTGAATCCCGGGGACGCGGCTTCGCCGCCG
CGTCCCGGATGGAGTGATAC

Downstream 100 bases:

>100_bases
CTCCGGCGGGATAATCGGAATAAAATCCGGCCTCTTTTTGTGGACTGACCAATCGTAGTCAGTCGCAGCCGGAATAATCC
GCCCGAGGCGGCCCGTGGTG

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1404; Mature: 1404

Protein sequence:

>1404_residues
MKSLLADLFKQTLPNEEEFDAITIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRL
KHRGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLNRAQ
LLTEDDYLAKVEEYGDDFDAVMGAEGIRELLRTLDVNQEIERLRSDLETTGSEAKIKKFSKRLKVLEAFQQSGIKPEWMI
LEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPDIIVRNEKRMLQESVDSLLDNGRRGKAMTG
ANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPQLKLHQCGLPKLMALELFKPFIFNKLELMGLATTIKQAK
KMVESQEPVVWDILEDVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCVAFNADFDGDQMAVHVPLSLEAQM
EARTLMLASNNVLSPANGDPIIVPSQDIVLGLYYATREGVNVPGEGMLFTDVGEVKRAYESGQISLHARVTVRLKEFDRG
PEGERIERVVRHNTTAGRAILSEILPAGLPFSVIDKPLKKKEISKLINASFRRCGLRATVIFADQLMQYGYRLATRAGIS
IAVKDMLVPDLKEDLIRAAEAEVKEIAQQYTSGLVTDGERYNKVVDIWGRCGDQVAKAMMEQLGQEPVVDRNGNTVKQEA
FNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITTNFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
RLVDVTQDLVVIEDDCGTREGFNMKALIEGGEVVEPLRERILGRVCAEDVVNPDTQETAIEAGTLLDEDMVDLIESLGVD
EVKVRTPLTCETRYGLCAKCYGRDLGRGAMVNAGEAVGVIAAQSIGEPGTQLTMRTFHVGGAASRAAAASGVEAKSSGTI
RFAGNMRYVANAKGEKVVIARSAEVVVADDMGRERERHKLPYGAMLLVDDGAQVKAGAQLASWDPHTRPIVTEYSGTVKF
ENVEEGVTVAKQIDEVTGLSTLVVIDSKRRSSSGAAKGVRPQVKLLDENGEEVRIAGTDHAVAITFQVGSLITVKDGQQV
SVGDILARIPQESAKTRDITGGLPRVAELFEARSPKDAGLLAEYTGTVSFGKDTKGKQRLVITEPDGTVHEFLIPKDKHL
MVHDGQVVNKGELIVDGPADPHDILRLQGINELARYIIDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVITDPGDTKFIR
EEQVERSEVLDENDRIEAEGKLPAQYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRL
IPAGTGLAYHRSRRSQSAGEDLGIEHAWAPIETPAEEQHDISAS

Sequences:

>Translated_1404_residues
MKSLLADLFKQTLPNEEEFDAITIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRL
KHRGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLNRAQ
LLTEDDYLAKVEEYGDDFDAVMGAEGIRELLRTLDVNQEIERLRSDLETTGSEAKIKKFSKRLKVLEAFQQSGIKPEWMI
LEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPDIIVRNEKRMLQESVDSLLDNGRRGKAMTG
ANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPQLKLHQCGLPKLMALELFKPFIFNKLELMGLATTIKQAK
KMVESQEPVVWDILEDVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCVAFNADFDGDQMAVHVPLSLEAQM
EARTLMLASNNVLSPANGDPIIVPSQDIVLGLYYATREGVNVPGEGMLFTDVGEVKRAYESGQISLHARVTVRLKEFDRG
PEGERIERVVRHNTTAGRAILSEILPAGLPFSVIDKPLKKKEISKLINASFRRCGLRATVIFADQLMQYGYRLATRAGIS
IAVKDMLVPDLKEDLIRAAEAEVKEIAQQYTSGLVTDGERYNKVVDIWGRCGDQVAKAMMEQLGQEPVVDRNGNTVKQEA
FNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITTNFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
RLVDVTQDLVVIEDDCGTREGFNMKALIEGGEVVEPLRERILGRVCAEDVVNPDTQETAIEAGTLLDEDMVDLIESLGVD
EVKVRTPLTCETRYGLCAKCYGRDLGRGAMVNAGEAVGVIAAQSIGEPGTQLTMRTFHVGGAASRAAAASGVEAKSSGTI
RFAGNMRYVANAKGEKVVIARSAEVVVADDMGRERERHKLPYGAMLLVDDGAQVKAGAQLASWDPHTRPIVTEYSGTVKF
ENVEEGVTVAKQIDEVTGLSTLVVIDSKRRSSSGAAKGVRPQVKLLDENGEEVRIAGTDHAVAITFQVGSLITVKDGQQV
SVGDILARIPQESAKTRDITGGLPRVAELFEARSPKDAGLLAEYTGTVSFGKDTKGKQRLVITEPDGTVHEFLIPKDKHL
MVHDGQVVNKGELIVDGPADPHDILRLQGINELARYIIDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVITDPGDTKFIR
EEQVERSEVLDENDRIEAEGKLPAQYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRL
IPAGTGLAYHRSRRSQSAGEDLGIEHAWAPIETPAEEQHDISAS
>Mature_1404_residues
MKSLLADLFKQTLPNEEEFDAITIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRL
KHRGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLNRAQ
LLTEDDYLAKVEEYGDDFDAVMGAEGIRELLRTLDVNQEIERLRSDLETTGSEAKIKKFSKRLKVLEAFQQSGIKPEWMI
LEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPDIIVRNEKRMLQESVDSLLDNGRRGKAMTG
ANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPQLKLHQCGLPKLMALELFKPFIFNKLELMGLATTIKQAK
KMVESQEPVVWDILEDVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCVAFNADFDGDQMAVHVPLSLEAQM
EARTLMLASNNVLSPANGDPIIVPSQDIVLGLYYATREGVNVPGEGMLFTDVGEVKRAYESGQISLHARVTVRLKEFDRG
PEGERIERVVRHNTTAGRAILSEILPAGLPFSVIDKPLKKKEISKLINASFRRCGLRATVIFADQLMQYGYRLATRAGIS
IAVKDMLVPDLKEDLIRAAEAEVKEIAQQYTSGLVTDGERYNKVVDIWGRCGDQVAKAMMEQLGQEPVVDRNGNTVKQEA
FNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITTNFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
RLVDVTQDLVVIEDDCGTREGFNMKALIEGGEVVEPLRERILGRVCAEDVVNPDTQETAIEAGTLLDEDMVDLIESLGVD
EVKVRTPLTCETRYGLCAKCYGRDLGRGAMVNAGEAVGVIAAQSIGEPGTQLTMRTFHVGGAASRAAAASGVEAKSSGTI
RFAGNMRYVANAKGEKVVIARSAEVVVADDMGRERERHKLPYGAMLLVDDGAQVKAGAQLASWDPHTRPIVTEYSGTVKF
ENVEEGVTVAKQIDEVTGLSTLVVIDSKRRSSSGAAKGVRPQVKLLDENGEEVRIAGTDHAVAITFQVGSLITVKDGQQV
SVGDILARIPQESAKTRDITGGLPRVAELFEARSPKDAGLLAEYTGTVSFGKDTKGKQRLVITEPDGTVHEFLIPKDKHL
MVHDGQVVNKGELIVDGPADPHDILRLQGINELARYIIDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVITDPGDTKFIR
EEQVERSEVLDENDRIEAEGKLPAQYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRL
IPAGTGLAYHRSRRSQSAGEDLGIEHAWAPIETPAEEQHDISAS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI39725938, Length=1033, Percent_Identity=24.1045498547919, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI4505939, Length=942, Percent_Identity=24.3099787685775, Blast_Score=179, Evalue=2e-44,
Organism=Homo sapiens, GI103471997, Length=238, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=3e-15,
Organism=Escherichia coli, GI2367335, Length=1382, Percent_Identity=68.5238784370478, Blast_Score=1929, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=662, Percent_Identity=26.4350453172205, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71987878, Length=579, Percent_Identity=26.5975820379965, Blast_Score=150, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6320061, Length=901, Percent_Identity=23.5294117647059, Blast_Score=169, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324690, Length=740, Percent_Identity=25.1351351351351, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI281360912, Length=1008, Percent_Identity=25.297619047619, Blast_Score=197, Evalue=4e-50,
Organism=Drosophila melanogaster, GI17530899, Length=575, Percent_Identity=25.9130434782609, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI17647875, Length=698, Percent_Identity=23.6389684813754, Blast_Score=124, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 155016; Mature: 155016

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLLADLFKQTLPNEEEFDAITIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFC
CHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEE
AKIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLK
EHHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHH
SLPSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLNRAQLLTEDDYLAKVEEYGDDFDA
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHCCCCHHHHHHHHCCCCHHH
VMGAEGIRELLRTLDVNQEIERLRSDLETTGSEAKIKKFSKRLKVLEAFQQSGIKPEWMI
HHCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPDIIVRNEKRM
EEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQESVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVG
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEC
PQLKLHQCGLPKLMALELFKPFIFNKLELMGLATTIKQAKKMVESQEPVVWDILEDVIRE
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCVAFNADFDGDQMAVHVPLSLEAQM
CCEEECCCCCHHHHCHHHCCCEEEECCEEEEEEEEEEEEECCCCCCCEEEEECCCCCCCH
EARTLMLASNNVLSPANGDPIIVPSQDIVLGLYYATREGVNVPGEGMLFTDVGEVKRAYE
HHEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCCCCEEEECHHHHHHHHH
SGQISLHARVTVRLKEFDRGPEGERIERVVRHNTTAGRAILSEILPAGLPFSVIDKPLKK
CCCEEEEEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHCCHHHH
KEISKLINASFRRCGLRATVIFADQLMQYGYRLATRAGISIAVKDMLVPDLKEDLIRAAE
HHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCHHHHHHHHHHH
AEVKEIAQQYTSGLVTDGERYNKVVDIWGRCGDQVAKAMMEQLGQEPVVDRNGNTVKQEA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
FNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITTNFREGLNVLQYFISTHG
CCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCC
ARKGLADTALKTANSGYLTRRLVDVTQDLVVIEDDCGTREGFNMKALIEGGEVVEPLRER
CCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHH
ILGRVCAEDVVNPDTQETAIEAGTLLDEDMVDLIESLGVDEVKVRTPLTCETRYGLCAKC
HHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCCHHHHH
YGRDLGRGAMVNAGEAVGVIAAQSIGEPGTQLTMRTFHVGGAASRAAAASGVEAKSSGTI
HCCCCCCCCEECCCCHHEEEEHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCCEE
RFAGNMRYVANAKGEKVVIARSAEVVVADDMGRERERHKLPYGAMLLVDDGAQVKAGAQL
EEECCEEEEECCCCCEEEEEECCCEEEECCCCCHHHHHCCCCCEEEEEECCCCEECCCEE
ASWDPHTRPIVTEYSGTVKFENVEEGVTVAKQIDEVTGLSTLVVIDSKRRSSSGAAKGVR
CCCCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
PQVKLLDENGEEVRIAGTDHAVAITFQVGSLITVKDGQQVSVGDILARIPQESAKTRDIT
CEEEEECCCCCEEEEECCCCEEEEEEEECCEEEECCCCEECHHHHHHHCCCHHCCCCCCC
GGLPRVAELFEARSPKDAGLLAEYTGTVSFGKDTKGKQRLVITEPDGTVHEFLIPKDKHL
CCCHHHHHHHHCCCCCCCCCEEEECCCEEECCCCCCCCEEEEECCCCCEEHEECCCCCEE
MVHDGQVVNKGELIVDGPADPHDILRLQGINELARYIIDEVQDVYRLQGVKINDKHIEVI
EEECCEEECCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHH
VRQMLRRVVITDPGDTKFIREEQVERSEVLDENDRIEAEGKLPAQYENVLLGITKASLST
HHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCHHHCCEEEEEEHHCCCC
DSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHRSRRSQSAGE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCEEEEEECCCCCHHHHHHHHCCCCCC
DLGIEHAWAPIETPAEEQHDISAS
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSLLADLFKQTLPNEEEFDAITIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFC
CHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEE
AKIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLK
EHHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHH
SLPSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLNRAQLLTEDDYLAKVEEYGDDFDA
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHCCCCHHHHHHHHCCCCHHH
VMGAEGIRELLRTLDVNQEIERLRSDLETTGSEAKIKKFSKRLKVLEAFQQSGIKPEWMI
HHCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPDIIVRNEKRM
EEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQESVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVG
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEC
PQLKLHQCGLPKLMALELFKPFIFNKLELMGLATTIKQAKKMVESQEPVVWDILEDVIRE
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCVAFNADFDGDQMAVHVPLSLEAQM
CCEEECCCCCHHHHCHHHCCCEEEECCEEEEEEEEEEEEECCCCCCCEEEEECCCCCCCH
EARTLMLASNNVLSPANGDPIIVPSQDIVLGLYYATREGVNVPGEGMLFTDVGEVKRAYE
HHEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCCCCEEEECHHHHHHHHH
SGQISLHARVTVRLKEFDRGPEGERIERVVRHNTTAGRAILSEILPAGLPFSVIDKPLKK
CCCEEEEEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHCCHHHH
KEISKLINASFRRCGLRATVIFADQLMQYGYRLATRAGISIAVKDMLVPDLKEDLIRAAE
HHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCHHHHHHHHHHH
AEVKEIAQQYTSGLVTDGERYNKVVDIWGRCGDQVAKAMMEQLGQEPVVDRNGNTVKQEA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
FNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITTNFREGLNVLQYFISTHG
CCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCC
ARKGLADTALKTANSGYLTRRLVDVTQDLVVIEDDCGTREGFNMKALIEGGEVVEPLRER
CCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHH
ILGRVCAEDVVNPDTQETAIEAGTLLDEDMVDLIESLGVDEVKVRTPLTCETRYGLCAKC
HHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCCHHHHH
YGRDLGRGAMVNAGEAVGVIAAQSIGEPGTQLTMRTFHVGGAASRAAAASGVEAKSSGTI
HCCCCCCCCEECCCCHHEEEEHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCCEE
RFAGNMRYVANAKGEKVVIARSAEVVVADDMGRERERHKLPYGAMLLVDDGAQVKAGAQL
EEECCEEEEECCCCCEEEEEECCCEEEECCCCCHHHHHCCCCCEEEEEECCCCEECCCEE
ASWDPHTRPIVTEYSGTVKFENVEEGVTVAKQIDEVTGLSTLVVIDSKRRSSSGAAKGVR
CCCCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
PQVKLLDENGEEVRIAGTDHAVAITFQVGSLITVKDGQQVSVGDILARIPQESAKTRDIT
CEEEEECCCCCEEEEECCCCEEEEEEEECCEEEECCCCEECHHHHHHHCCCHHCCCCCCC
GGLPRVAELFEARSPKDAGLLAEYTGTVSFGKDTKGKQRLVITEPDGTVHEFLIPKDKHL
CCCHHHHHHHHCCCCCCCCCEEEECCCEEECCCCCCCCEEEEECCCCCEEHEECCCCCEE
MVHDGQVVNKGELIVDGPADPHDILRLQGINELARYIIDEVQDVYRLQGVKINDKHIEVI
EEECCEEECCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHH
VRQMLRRVVITDPGDTKFIREEQVERSEVLDENDRIEAEGKLPAQYENVLLGITKASLST
HHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCHHHCCEEEEEEHHCCCC
DSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHRSRRSQSAGE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCEEEEEECCCCCHHHHHHHHCCCCCC
DLGIEHAWAPIETPAEEQHDISAS
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA