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The map label for this gene is ygdL [C]

Identifier: 119899667

GI number: 119899667

Start: 3712312

End: 3713148

Strand: Reverse

Name: ygdL [C]

Synonym: azo3378

Alternate gene names: 119899667

Gene position: 3713148-3712312 (Counterclockwise)

Preceding gene: 119899668

Following gene: 119899666

Centisome position: 84.85

GC content: 70.25

Gene sequence:

>837_bases
ATGTCCGATTCCCCTGCTGAACTCCTTGCCCCGCTCGACGAGGCTGTCGCCGCCGAGGCCGACGGCGGTCGCCGTTTCGG
CGGCATCGCGCGTTTGTACGACGATGCTGCCCTTCATCGCCTGAATCTGGCCCACGTCTGTGTGGTCGGAATCGGCGGCG
TCGGTTCGTGGGCGGCGGAAGCGCTGGCGCGCAGCGGCGTGGGCCGTCTGACGCTGATCGATCTCGACCACGTGGCCGAA
TCCAACATCAACCGCCAGGCGCACGCGCTCGATGCCACCCTGGGGCAGGCCAAGGTCCAGGCAATGGCCGAACGCATCCG
CGGCATCAATCCGCGCGCCCGCGTCGATACCGTGGAGGATTTTGTCGAGCCGGACAACGTGGCCGCGCTGCTGCGCGAGT
TCAACCTCGTCATCGACGCCATCGACAACGTCCGCGCCAAGGTTGCGATGGCGGTCCATTGCCGGCGCGCCCGGTTGCCG
CTGCTGATGGCGGGCGGCGCCGGCGGCAAGCGCGACCCGGGCCGCATCCGTGTCGCCGACCTCGTCGCCACCGAGCAGGA
CCCCCTGCTGGCCAAGGTGCGCGCCACGCTGCGGCGCGACCACGCTTTTCCGCGCGCGGCGGGCAAGAAGTTCGGCATCG
AAGTGGTGTACTCCAGCGAGCCGCTACGCTACCCGGCGGCAAGCTGCGAGACCGGCCGCGGGCCGCAGGGGCTCGCCTGC
GCGGGCTTTGGTTCCAGCATGGCGGTGACGGCGAGCGTCGGGCTGTTTCTCGCCGCCCGCGCAATCGACCGGCTGGTGGC
GAAGCCGGTCGCGGCCGAAGCGGGAGCAAACGCATGA

Upstream 100 bases:

>100_bases
GCCCTTGCCCTGCACGCGCGTTGGAGAAGCGGCGGACGCGAGTTCAGCCGGCCGTCCCGGCTGCGGTAACATCGCTTCGC
CTGTGTTTCCGCTCACCGTC

Downstream 100 bases:

>100_bases
ACGCGACGATGCCAAGCGGGCAGGCGGCAACGCCGGCCGACACCGTGTTGCTGTTCGGCCACGGCGCGCGCGACCCGCAA
TGGGCCGGGCCGATGCAGCG

Product: HesA/MoeB/ThiF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSDSPAELLAPLDEAVAAEADGGRRFGGIARLYDDAALHRLNLAHVCVVGIGGVGSWAAEALARSGVGRLTLIDLDHVAE
SNINRQAHALDATLGQAKVQAMAERIRGINPRARVDTVEDFVEPDNVAALLREFNLVIDAIDNVRAKVAMAVHCRRARLP
LLMAGGAGGKRDPGRIRVADLVATEQDPLLAKVRATLRRDHAFPRAAGKKFGIEVVYSSEPLRYPAASCETGRGPQGLAC
AGFGSSMAVTASVGLFLAARAIDRLVAKPVAAEAGANA

Sequences:

>Translated_278_residues
MSDSPAELLAPLDEAVAAEADGGRRFGGIARLYDDAALHRLNLAHVCVVGIGGVGSWAAEALARSGVGRLTLIDLDHVAE
SNINRQAHALDATLGQAKVQAMAERIRGINPRARVDTVEDFVEPDNVAALLREFNLVIDAIDNVRAKVAMAVHCRRARLP
LLMAGGAGGKRDPGRIRVADLVATEQDPLLAKVRATLRRDHAFPRAAGKKFGIEVVYSSEPLRYPAASCETGRGPQGLAC
AGFGSSMAVTASVGLFLAARAIDRLVAKPVAAEAGANA
>Mature_277_residues
SDSPAELLAPLDEAVAAEADGGRRFGGIARLYDDAALHRLNLAHVCVVGIGGVGSWAAEALARSGVGRLTLIDLDHVAES
NINRQAHALDATLGQAKVQAMAERIRGINPRARVDTVEDFVEPDNVAALLREFNLVIDAIDNVRAKVAMAVHCRRARLPL
LMAGGAGGKRDPGRIRVADLVATEQDPLLAKVRATLRRDHAFPRAAGKKFGIEVVYSSEPLRYPAASCETGRGPQGLACA
GFGSSMAVTASVGLFLAARAIDRLVAKPVAAEAGANA

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=124, Percent_Identity=34.6774193548387, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7657339, Length=139, Percent_Identity=35.9712230215827, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789177, Length=253, Percent_Identity=50.5928853754941, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1787048, Length=134, Percent_Identity=38.0597014925373, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082356, Length=140, Percent_Identity=29.2857142857143, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17540406, Length=118, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321790, Length=194, Percent_Identity=28.3505154639175, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322825, Length=233, Percent_Identity=26.1802575107296, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6325438, Length=139, Percent_Identity=28.0575539568345, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582879, Length=141, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24660640, Length=126, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29136; Mature: 29004

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSPAELLAPLDEAVAAEADGGRRFGGIARLYDDAALHRLNLAHVCVVGIGGVGSWAAE
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHH
ALARSGVGRLTLIDLDHVAESNINRQAHALDATLGQAKVQAMAERIRGINPRARVDTVED
HHHHCCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FVEPDNVAALLREFNLVIDAIDNVRAKVAMAVHCRRARLPLLMAGGAGGKRDPGRIRVAD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEE
LVATEQDPLLAKVRATLRRDHAFPRAAGKKFGIEVVYSSEPLRYPAASCETGRGPQGLAC
EEECCCCHHHHHHHHHHHHHCCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
AGFGSSMAVTASVGLFLAARAIDRLVAKPVAAEAGANA
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCC
>Mature Secondary Structure 
SDSPAELLAPLDEAVAAEADGGRRFGGIARLYDDAALHRLNLAHVCVVGIGGVGSWAAE
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHH
ALARSGVGRLTLIDLDHVAESNINRQAHALDATLGQAKVQAMAERIRGINPRARVDTVED
HHHHCCCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FVEPDNVAALLREFNLVIDAIDNVRAKVAMAVHCRRARLPLLMAGGAGGKRDPGRIRVAD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEE
LVATEQDPLLAKVRATLRRDHAFPRAAGKKFGIEVVYSSEPLRYPAASCETGRGPQGLAC
EEECCCCHHHHHHHHHHHHHCCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
AGFGSSMAVTASVGLFLAARAIDRLVAKPVAAEAGANA
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]