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The map label for this gene is cat1 [H]

Identifier: 119899596

GI number: 119899596

Start: 3643550

End: 3645082

Strand: Reverse

Name: cat1 [H]

Synonym: azo3307

Alternate gene names: 119899596

Gene position: 3645082-3643550 (Counterclockwise)

Preceding gene: 119899597

Following gene: 119899595

Centisome position: 83.3

GC content: 65.88

Gene sequence:

>1533_bases
ATGTCCAACTCGCTTTCCAACCCGAACGCCGACCGCGTCCTCTCGCCGCGTCTGCGCAACAAGATCATGTCCGCCGAGGC
CGCCGCCGCCCTCATCCCGTCCGGGGTGAATGTCGGCATGAGCGGCTTCACCGGCGCCGGCTACCCCAAGGCGGTGCCGG
CCGCGCTCGCCAAGCGCATCATGGATGCCAACCTCAACGGCAAGAACTTCAAGATCGGCGTATGGACCGGCGCCTCCACC
GCGCCCGAACTCGACGGCGCGCTCGCGATGGTCGACGGCGTGGAGCTGCGCCTGCCCTACCAGTCCGACCCCACCTGCCG
CAAGCGCATCAATGCCGGCGAGATGGAATACCTCGACATGCACCTGTCGCAGGTCGCGCAGTTCGTCTGGTTCGGCTTCC
TCGGCAAGCTCGACGTGGCGGTGGTGGAAGTGGCGGGCATCCTGGAGGACGGCCGCCTGGTGCCGTCGTCCTCGGTGGGT
AACAACAAGACCTGGCTGGATCAGGCCGACAAGGTCATCCTGGAAGTGAACAGCTGGCAGAACCCGGCGCTGGAAGGGAT
GCACGACATCTACTACGGCACCGCGCTGCCGCCGTACCGCAAGCCGATCCCGCTGCTGAAGACCGACGACCGCATCGGCG
AACCTTATCTGCGTTGCGACCCGGACAAGATCATCGCGGTGGTCGAAACCCATACCCCGGACCGCAACTCGGCGTTTTCC
GCGCCGGACGAGAACTCCCGCCGCATCGCCGGTCACATCCTCGAATTCCTCGAGCACGAGGTGAAGAAGGGCCGCCTGCC
GCCCAACCTGCTGCCGCTGCAGTCGGGCGTGGGCAACATTGCCAACGCGGTGATGGCGGGGCTCAACGAGGGCCCGTTCG
ACAACCTCACCGCCTACACCGAGGTGCTGCAGGACGGCATGCTCGACCTGATCAAGTCGGGCAAGCTCAGCTGCGCTTCC
GCCACCGCGTTTTCGCTGTCGCCGGCCGCGCTGTCCGAACTCAATGCCGACCTCGCGCGCTACCGCGAGCGCATCATCCT
GCGCCCGCAGGAGATCTCGAATCATCCGGAGCTGATCCGCCGCCTCGGCGTGATCGCGATGAACGGCATGATCGAGGCCG
ACATCTACGGCAACGTGAACTCCACCCATGTGATGGGCACGCGGATCATGAACGGCATCGGCGGCTCGGGCGATTTCGCG
CGCAACGCCTACATCTCGATCTTCATGACGCCGTCGCAGGCCAAGGGCGGCGACATCTCCTGCATCGTGCCGATGGCGTC
GCACGTGGACCACACCGAGCACGACGTGCAGGTACTGGTGACCGAGCAGGGCCTGGCCGACCTGCGCGGGCTGTCGCCCA
AGCAGCGCGCGCGCGTGATCATCGACAACTGTGCGCACCCGCACTTCCGCCCGGCGCTGATGGATTACTACAAGCGCTCG
CTGATGCACTCCGAAGGCAAGCAGACGCCGCACCTGCTGGACGAGGCGCTGTCCTGGCACCTGAAGTACCTGCGCGGCGG
CCAGATGTTGTAA

Upstream 100 bases:

>100_bases
CGTGCCGCGGACCGACAGCGCAGGGCGGGAGCGAGGAGGCAGAAGTGGCGTTCCTGGAGGGAGCGCCGTGTCAGACCTAC
AGGCCCAGGCCCATACCAGA

Downstream 100 bases:

>100_bases
GTCGCGCGGCGGTGTAGAGTCGGGGGCAGGCACCCGCCCGGCGCGGCGGGGCCCACCAACAACAAGAGGCCGATCCTGGA
GACGACCGCCCCCGCCCTCC

Product: coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSNSLSNPNADRVLSPRLRNKIMSAEAAAALIPSGVNVGMSGFTGAGYPKAVPAALAKRIMDANLNGKNFKIGVWTGAST
APELDGALAMVDGVELRLPYQSDPTCRKRINAGEMEYLDMHLSQVAQFVWFGFLGKLDVAVVEVAGILEDGRLVPSSSVG
NNKTWLDQADKVILEVNSWQNPALEGMHDIYYGTALPPYRKPIPLLKTDDRIGEPYLRCDPDKIIAVVETHTPDRNSAFS
APDENSRRIAGHILEFLEHEVKKGRLPPNLLPLQSGVGNIANAVMAGLNEGPFDNLTAYTEVLQDGMLDLIKSGKLSCAS
ATAFSLSPAALSELNADLARYRERIILRPQEISNHPELIRRLGVIAMNGMIEADIYGNVNSTHVMGTRIMNGIGGSGDFA
RNAYISIFMTPSQAKGGDISCIVPMASHVDHTEHDVQVLVTEQGLADLRGLSPKQRARVIIDNCAHPHFRPALMDYYKRS
LMHSEGKQTPHLLDEALSWHLKYLRGGQML

Sequences:

>Translated_510_residues
MSNSLSNPNADRVLSPRLRNKIMSAEAAAALIPSGVNVGMSGFTGAGYPKAVPAALAKRIMDANLNGKNFKIGVWTGAST
APELDGALAMVDGVELRLPYQSDPTCRKRINAGEMEYLDMHLSQVAQFVWFGFLGKLDVAVVEVAGILEDGRLVPSSSVG
NNKTWLDQADKVILEVNSWQNPALEGMHDIYYGTALPPYRKPIPLLKTDDRIGEPYLRCDPDKIIAVVETHTPDRNSAFS
APDENSRRIAGHILEFLEHEVKKGRLPPNLLPLQSGVGNIANAVMAGLNEGPFDNLTAYTEVLQDGMLDLIKSGKLSCAS
ATAFSLSPAALSELNADLARYRERIILRPQEISNHPELIRRLGVIAMNGMIEADIYGNVNSTHVMGTRIMNGIGGSGDFA
RNAYISIFMTPSQAKGGDISCIVPMASHVDHTEHDVQVLVTEQGLADLRGLSPKQRARVIIDNCAHPHFRPALMDYYKRS
LMHSEGKQTPHLLDEALSWHLKYLRGGQML
>Mature_509_residues
SNSLSNPNADRVLSPRLRNKIMSAEAAAALIPSGVNVGMSGFTGAGYPKAVPAALAKRIMDANLNGKNFKIGVWTGASTA
PELDGALAMVDGVELRLPYQSDPTCRKRINAGEMEYLDMHLSQVAQFVWFGFLGKLDVAVVEVAGILEDGRLVPSSSVGN
NKTWLDQADKVILEVNSWQNPALEGMHDIYYGTALPPYRKPIPLLKTDDRIGEPYLRCDPDKIIAVVETHTPDRNSAFSA
PDENSRRIAGHILEFLEHEVKKGRLPPNLLPLQSGVGNIANAVMAGLNEGPFDNLTAYTEVLQDGMLDLIKSGKLSCASA
TAFSLSPAALSELNADLARYRERIILRPQEISNHPELIRRLGVIAMNGMIEADIYGNVNSTHVMGTRIMNGIGGSGDFAR
NAYISIFMTPSQAKGGDISCIVPMASHVDHTEHDVQVLVTEQGLADLRGLSPKQRARVIIDNCAHPHFRPALMDYYKRSL
MHSEGKQTPHLLDEALSWHLKYLRGGQML

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=489, Percent_Identity=48.4662576687117, Blast_Score=461, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17538151, Length=478, Percent_Identity=25.1046025104602, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=226, Percent_Identity=31.4159292035398, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319456, Length=520, Percent_Identity=45.1923076923077, Blast_Score=427, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55633; Mature: 55502

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSLSNPNADRVLSPRLRNKIMSAEAAAALIPSGVNVGMSGFTGAGYPKAVPAALAKRI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
MDANLNGKNFKIGVWTGASTAPELDGALAMVDGVELRLPYQSDPTCRKRINAGEMEYLDM
HHCCCCCCEEEEEEEECCCCCCCCCCCEEEECCEEEEECCCCCCHHHHHCCCCCHHHHHH
HLSQVAQFVWFGFLGKLDVAVVEVAGILEDGRLVPSSSVGNNKTWLDQADKVILEVNSWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCC
NPALEGMHDIYYGTALPPYRKPIPLLKTDDRIGEPYLRCDPDKIIAVVETHTPDRNSAFS
CCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCEEECCCCEEEEEEECCCCCCCCCC
APDENSRRIAGHILEFLEHEVKKGRLPPNLLPLQSGVGNIANAVMAGLNEGPFDNLTAYT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCHHHHHHHHHHCCCCCCCCHHHHHH
EVLQDGMLDLIKSGKLSCASATAFSLSPAALSELNADLARYRERIILRPQEISNHPELIR
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHH
RLGVIAMNGMIEADIYGNVNSTHVMGTRIMNGIGGSGDFARNAYISIFMTPSQAKGGDIS
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEE
CIVPMASHVDHTEHDVQVLVTEQGLADLRGLSPKQRARVIIDNCAHPHFRPALMDYYKRS
EEEECHHCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHEECCCCCCCCHHHHHHHHHH
LMHSEGKQTPHLLDEALSWHLKYLRGGQML
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SNSLSNPNADRVLSPRLRNKIMSAEAAAALIPSGVNVGMSGFTGAGYPKAVPAALAKRI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
MDANLNGKNFKIGVWTGASTAPELDGALAMVDGVELRLPYQSDPTCRKRINAGEMEYLDM
HHCCCCCCEEEEEEEECCCCCCCCCCCEEEECCEEEEECCCCCCHHHHHCCCCCHHHHHH
HLSQVAQFVWFGFLGKLDVAVVEVAGILEDGRLVPSSSVGNNKTWLDQADKVILEVNSWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCC
NPALEGMHDIYYGTALPPYRKPIPLLKTDDRIGEPYLRCDPDKIIAVVETHTPDRNSAFS
CCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCEEECCCCEEEEEEECCCCCCCCCC
APDENSRRIAGHILEFLEHEVKKGRLPPNLLPLQSGVGNIANAVMAGLNEGPFDNLTAYT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCHHHHHHHHHHCCCCCCCCHHHHHH
EVLQDGMLDLIKSGKLSCASATAFSLSPAALSELNADLARYRERIILRPQEISNHPELIR
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHH
RLGVIAMNGMIEADIYGNVNSTHVMGTRIMNGIGGSGDFARNAYISIFMTPSQAKGGDIS
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEE
CIVPMASHVDHTEHDVQVLVTEQGLADLRGLSPKQRARVIIDNCAHPHFRPALMDYYKRS
EEEECHHCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHEECCCCCCCCHHHHHHHHHH
LMHSEGKQTPHLLDEALSWHLKYLRGGQML
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]