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The map label for this gene is coxC [H]

Identifier: 119899588

GI number: 119899588

Start: 3636240

End: 3637091

Strand: Reverse

Name: coxC [H]

Synonym: azo3299

Alternate gene names: 119899588

Gene position: 3637091-3636240 (Counterclockwise)

Preceding gene: 119899589

Following gene: 119899586

Centisome position: 83.11

GC content: 64.44

Gene sequence:

>852_bases
ATGACCGAAGCACTCGAACGTTATTTCGTGCCGGAGCCGTCGAAATTCCCGATCTTCGGCTCGGTGGCGCTGCTGCTGTT
CGGCACCGGCGCGGCGCTGTGGGTCAATCACGTGCCGGCCGGGCCGTGGGTGTTCTTCGCCGGCATCGCGATCCTGATCT
ACATGCTGTTCGGCTGGTTCGGCACCGTCGTGCGCGAATCGGAGTCCGGCAAGTACGGGCACCAGGTGGATACCGCCTTC
CGCTGGTCGATGGGCTGGTTCATCTTCTCCGAGGTGATGTTCTTCGCCGCCTTCTTCGGTGCGCTGTTCTACGTGCGCGT
GCTGGCGGTGCCGGCGCTGTCGTCGGGCGACAACCTTTCCTTGTTGTGGCAGGGCTACAACGGCGCATGGCCCAACGCGG
GGCCGAACGCGGCGGAAAACTTCACGCCGATGGGCGCGTGGGGCATCCCCGCGATCAACACGCTGATCCTGCTCAGTTCC
GGCGCGACCCTCACCTGGGCGCACTACGGCCTGCTGAAGGGCAACCGCGGCCAACTCAAGCTCGGGCTGCTGGTCACGAT
CCTGCTGGGCGCGGTGTTTCTTGCGCTGCAAGCCTACGAATACATCCACGCCTATGCCGAGCTCAACCTGCGGCTGGACA
CCGGCATCTACGGCTCGACCTTCTTCATGCTCACCGGCTTTCACGGCATGCATGTGACCGTGGGCGCCATCATGCTGACG
GTGATGCTGGCGCGCGCGATGGCCGGCCACTTCACCCCGGATAGCCACTTCGGCTTCGAGGCCGCGGCGTGGTACTGGCA
CTTCGTGGACGTGGTGTGGCTGTTCCTGTTCGTCGTCGTCTACTGGCTGTAG

Upstream 100 bases:

>100_bases
CTCGCCGGCGCGGTGTTCGTGCTGGGACTGCTGACGCTGGTGTACTGGGTGGTGGGCTAGGGCGCCTTCCCTGTGGGAGG
GCTGCGGCAAGGAGGCAACC

Downstream 100 bases:

>100_bases
CGGCGGGGCGGGATCACAGCTTGCTGTCGATCAGGCCCGTGGCAAAGCCCGCCATCAGCAGCGTGAACAGGGTGATCGAC
AGCCCGACCCGCAGCGCCAG

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTEALERYFVPEPSKFPIFGSVALLLFGTGAALWVNHVPAGPWVFFAGIAILIYMLFGWFGTVVRESESGKYGHQVDTAF
RWSMGWFIFSEVMFFAAFFGALFYVRVLAVPALSSGDNLSLLWQGYNGAWPNAGPNAAENFTPMGAWGIPAINTLILLSS
GATLTWAHYGLLKGNRGQLKLGLLVTILLGAVFLALQAYEYIHAYAELNLRLDTGIYGSTFFMLTGFHGMHVTVGAIMLT
VMLARAMAGHFTPDSHFGFEAAAWYWHFVDVVWLFLFVVVYWL

Sequences:

>Translated_283_residues
MTEALERYFVPEPSKFPIFGSVALLLFGTGAALWVNHVPAGPWVFFAGIAILIYMLFGWFGTVVRESESGKYGHQVDTAF
RWSMGWFIFSEVMFFAAFFGALFYVRVLAVPALSSGDNLSLLWQGYNGAWPNAGPNAAENFTPMGAWGIPAINTLILLSS
GATLTWAHYGLLKGNRGQLKLGLLVTILLGAVFLALQAYEYIHAYAELNLRLDTGIYGSTFFMLTGFHGMHVTVGAIMLT
VMLARAMAGHFTPDSHFGFEAAAWYWHFVDVVWLFLFVVVYWL
>Mature_282_residues
TEALERYFVPEPSKFPIFGSVALLLFGTGAALWVNHVPAGPWVFFAGIAILIYMLFGWFGTVVRESESGKYGHQVDTAFR
WSMGWFIFSEVMFFAAFFGALFYVRVLAVPALSSGDNLSLLWQGYNGAWPNAGPNAAENFTPMGAWGIPAINTLILLSSG
ATLTWAHYGLLKGNRGQLKLGLLVTILLGAVFLALQAYEYIHAYAELNLRLDTGIYGSTFFMLTGFHGMHVTVGAIMLTV
MLARAMAGHFTPDSHFGFEAAAWYWHFVDVVWLFLFVVVYWL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=283, Percent_Identity=40.9893992932862, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1786633, Length=130, Percent_Identity=33.8461538461538, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6226542, Length=225, Percent_Identity=35.5555555555556, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31415; Mature: 31284

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEALERYFVPEPSKFPIFGSVALLLFGTGAALWVNHVPAGPWVFFAGIAILIYMLFGWF
CCHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
GTVVRESESGKYGHQVDTAFRWSMGWFIFSEVMFFAAFFGALFYVRVLAVPALSSGDNLS
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LLWQGYNGAWPNAGPNAAENFTPMGAWGIPAINTLILLSSGATLTWAHYGLLKGNRGQLK
EEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCCEEEEEEHHEEECCCCCCH
LGLLVTILLGAVFLALQAYEYIHAYAELNLRLDTGIYGSTFFMLTGFHGMHVTVGAIMLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHH
VMLARAMAGHFTPDSHFGFEAAAWYWHFVDVVWLFLFVVVYWL
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TEALERYFVPEPSKFPIFGSVALLLFGTGAALWVNHVPAGPWVFFAGIAILIYMLFGWF
CHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
GTVVRESESGKYGHQVDTAFRWSMGWFIFSEVMFFAAFFGALFYVRVLAVPALSSGDNLS
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LLWQGYNGAWPNAGPNAAENFTPMGAWGIPAINTLILLSSGATLTWAHYGLLKGNRGQLK
EEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCCEEEEEEHHEEECCCCCCH
LGLLVTILLGAVFLALQAYEYIHAYAELNLRLDTGIYGSTFFMLTGFHGMHVTVGAIMLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHH
VMLARAMAGHFTPDSHFGFEAAAWYWHFVDVVWLFLFVVVYWL
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]