Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 119899513

GI number: 119899513

Start: 3553798

End: 3554829

Strand: Reverse

Name: gcp

Synonym: azo3224

Alternate gene names: 119899513

Gene position: 3554829-3553798 (Counterclockwise)

Preceding gene: 119899517

Following gene: 119899511

Centisome position: 81.23

GC content: 67.73

Gene sequence:

>1032_bases
ATGAAAGTACTGGGTATCGAAACGTCGTGCGACGAAACAGGGGTCGCCATCTACGATGGAAGCGTGCGGCGCTTGCTGGG
GCACTGCCTGCACTCCCAGATCGATCTGCACGCCGCGTACGGGGGCGTGGTCCCGGAACTCGCGTCGCGCGACCACATCC
GGCGCTTGCCGCTCCTGCTGAAACAGCTCTTTGGCGAAACGGGACTTTCCCGCCGCGATATCGACGCAGTGGCCTACACC
GCGGGGCCGGGGCTTGCCGGTGCGCTGCTCACGGGAGCCAGCTTCGCGGAGGCGTTTGCCCTCGCGGCTGGCGTGCCGGC
ACTGCCAATTCATCACCTGGAGGGGCACCTGTTGTCGCCGCTGCTGGCGGATGACGCGCCCCGCTTCCCTTTTGTCGCGC
TGCTGGTATCCGGCGGCCATACCCAGTTGATGCATGTTGCCGGGGTCGGGCGCTACGAGCTGCTCGGCGAGTCGCTCGAC
GATGCGGCGGGCGAAGCCTTCGACAAGACCGCGAAACTGTTGGGCCTGGGCTATCCCGGCGGGCCGCAACTGTCCGCGCT
TGCTGCGCAGGGCTGCGCCGGTCGTTTCAAGTTGCCTCGTCCCATGCTGCATTCGGGCGATTTCGATTTCAGCTTCAGCG
GGCTGAAGACCGCCGTGTTGAACCGGGTGAGCAGCGACGACTGGGAGCCGGGGCTGGCAGCGGATCTGGCGGCTGACTTC
CAGGAGGCGGTGGTCGAGGTGCTGTGTGCCAAGGCGCTGGCGGCGCTCAAGCACACCGGGCTCGACACTCTGGTTGTCGC
CGGCGGAGTAGGGGCCAACCGACGCTTGCGCGAACGCCTTGATAATCTCGCCGCACGACGGCGGTATCGGGTGTGTTATC
CGGAGCCCGCGCTGTGTACCGACAACGGCGCAATGATTGCGTTTGCGGGCGCGTTGCGGCTGGAGGCCGGCGAGCGTCGA
GCGGCCGCGCCGGCGGTGCGGGTGCGGCCGCGCTGGCCGCTGGTCGAACTGGACGCCCCAGGCTGCCCCTGA

Upstream 100 bases:

>100_bases
AAGTTCGCGAGTCTACCCGTTGCGCGCCGCGGGTGCAAGATCGCACCGGAAAATTCGCCCGACCCGCCGTAGAATGGCGA
ACTCGCAATCGGGCGCTGTC

Downstream 100 bases:

>100_bases
TCAGCCCTTCTTGGCGCCGATGCGACCTTCGGTGCCGGCGAGCAGGCGGCGGATGTTGCCGTGATGTCGCCAGATGAGAA
CCGCCGACATCGCGGCCATG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKVLGIETSCDETGVAIYDGSVRRLLGHCLHSQIDLHAAYGGVVPELASRDHIRRLPLLLKQLFGETGLSRRDIDAVAYT
AGPGLAGALLTGASFAEAFALAAGVPALPIHHLEGHLLSPLLADDAPRFPFVALLVSGGHTQLMHVAGVGRYELLGESLD
DAAGEAFDKTAKLLGLGYPGGPQLSALAAQGCAGRFKLPRPMLHSGDFDFSFSGLKTAVLNRVSSDDWEPGLAADLAADF
QEAVVEVLCAKALAALKHTGLDTLVVAGGVGANRRLRERLDNLAARRRYRVCYPEPALCTDNGAMIAFAGALRLEAGERR
AAAPAVRVRPRWPLVELDAPGCP

Sequences:

>Translated_343_residues
MKVLGIETSCDETGVAIYDGSVRRLLGHCLHSQIDLHAAYGGVVPELASRDHIRRLPLLLKQLFGETGLSRRDIDAVAYT
AGPGLAGALLTGASFAEAFALAAGVPALPIHHLEGHLLSPLLADDAPRFPFVALLVSGGHTQLMHVAGVGRYELLGESLD
DAAGEAFDKTAKLLGLGYPGGPQLSALAAQGCAGRFKLPRPMLHSGDFDFSFSGLKTAVLNRVSSDDWEPGLAADLAADF
QEAVVEVLCAKALAALKHTGLDTLVVAGGVGANRRLRERLDNLAARRRYRVCYPEPALCTDNGAMIAFAGALRLEAGERR
AAAPAVRVRPRWPLVELDAPGCP
>Mature_343_residues
MKVLGIETSCDETGVAIYDGSVRRLLGHCLHSQIDLHAAYGGVVPELASRDHIRRLPLLLKQLFGETGLSRRDIDAVAYT
AGPGLAGALLTGASFAEAFALAAGVPALPIHHLEGHLLSPLLADDAPRFPFVALLVSGGHTQLMHVAGVGRYELLGESLD
DAAGEAFDKTAKLLGLGYPGGPQLSALAAQGCAGRFKLPRPMLHSGDFDFSFSGLKTAVLNRVSSDDWEPGLAADLAADF
QEAVVEVLCAKALAALKHTGLDTLVVAGGVGANRRLRERLDNLAARRRYRVCYPEPALCTDNGAMIAFAGALRLEAGERR
AAAPAVRVRPRWPLVELDAPGCP

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=356, Percent_Identity=36.2359550561798, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI8923380, Length=324, Percent_Identity=31.1728395061728, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=60.7669616519174, Blast_Score=402, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=33.434650455927, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=31.8042813455657, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=367, Percent_Identity=30.7901907356948, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6322891, Length=298, Percent_Identity=27.5167785234899, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI20129063, Length=341, Percent_Identity=34.6041055718475, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21357207, Length=334, Percent_Identity=30.2395209580838, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_AZOSB (A1KAI4)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934726.1
- ProteinModelPortal:   A1KAI4
- SMR:   A1KAI4
- STRING:   A1KAI4
- MEROPS:   M22.001
- GeneID:   4607856
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo3224
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   A1KAI4
- ProtClustDB:   PRK09604
- BioCyc:   ASP62928:AZO3224-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36173; Mature: 36173

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLGIETSCDETGVAIYDGSVRRLLGHCLHSQIDLHAAYGGVVPELASRDHIRRLPLLL
CEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHH
KQLFGETGLSRRDIDAVAYTAGPGLAGALLTGASFAEAFALAAGVPALPIHHLEGHLLSP
HHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHH
LLADDAPRFPFVALLVSGGHTQLMHVAGVGRYELLGESLDDAAGEAFDKTAKLLGLGYPG
HHHCCCCCCCEEEEEECCCCCEEEHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCCC
GPQLSALAAQGCAGRFKLPRPMLHSGDFDFSFSGLKTAVLNRVSSDDWEPGLAADLAADF
CCCHHHHHHHCCCCCCCCCCCHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QEAVVEVLCAKALAALKHTGLDTLVVAGGVGANRRLRERLDNLAARRRYRVCYPEPALCT
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEC
DNGAMIAFAGALRLEAGERRAAAPAVRVRPRWPLVELDAPGCP
CCCCEEEEEEEHEECCCCCCCCCCEEEECCCCCEEEECCCCCC
>Mature Secondary Structure
MKVLGIETSCDETGVAIYDGSVRRLLGHCLHSQIDLHAAYGGVVPELASRDHIRRLPLLL
CEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHH
KQLFGETGLSRRDIDAVAYTAGPGLAGALLTGASFAEAFALAAGVPALPIHHLEGHLLSP
HHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHH
LLADDAPRFPFVALLVSGGHTQLMHVAGVGRYELLGESLDDAAGEAFDKTAKLLGLGYPG
HHHCCCCCCCEEEEEECCCCCEEEHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCCC
GPQLSALAAQGCAGRFKLPRPMLHSGDFDFSFSGLKTAVLNRVSSDDWEPGLAADLAADF
CCCHHHHHHHCCCCCCCCCCCHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QEAVVEVLCAKALAALKHTGLDTLVVAGGVGANRRLRERLDNLAARRRYRVCYPEPALCT
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEC
DNGAMIAFAGALRLEAGERRAAAPAVRVRPRWPLVELDAPGCP
CCCCEEEEEEEHEECCCCCCCCCCEEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA