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The map label for this gene is xerD [H]

Identifier: 119899508

GI number: 119899508

Start: 3550691

End: 3551608

Strand: Direct

Name: xerD [H]

Synonym: azo3219

Alternate gene names: 119899508

Gene position: 3550691-3551608 (Clockwise)

Preceding gene: 119899507

Following gene: 119899509

Centisome position: 81.14

GC content: 63.94

Gene sequence:

>918_bases
GTGACCGCATTCGAACAACAGCTCTCGGCCGAGACGCGCGCCGAACTCGATCTGTTCTGCGACGCACTGTGGCTGGAATT
CGGCCTGGCAGCCAATACCATTGCCGGTTATCGGAGCGATCTCGCGCAATTCGGCGCCTGGCTGGCCAGCCGCGGGACTC
AATTGATCGAAGCGGACGAGAGCCAGCTCACCGCGTATCTCGCCGAATTCAGCCGCCGCGCCAAACCCGCCAGCCAGCGC
CGCCTGATGTCGGCCTGGCGCCGCTTTTACCGAGGGCTGCTCGGCCAGCGCCGTATCGCTCAGGATCCGACCGTCCAGCT
CGACGCCCCGGTGACCGGCGAACGCTTTCCCCGCACCCTCAGCGAAGCACAGGTGGAATCGCTGCTGGCAGCGCCCGACG
TCGACACGATTCACGGCCTGCGGGACCGCAGCATGCTTGAATTGCTGTATGCGAGCGGGCTTCGTGTTTCCGAGCTGGTG
GAATTGAAACTCTTTGCGATCAGCACCGGCGAAGGCGTAATCCGCGTGTTCGGCAAAGGCAGCAAGGAACGCCTCGTTCC
CACCGGCGACATCGCGCTCGAGTGGCTCGGCCGCTACCTGCGCGAAGCGCGGCCAGCCCTGTTGCGCGGGCGGACATGCG
ACGAGGTTTTCGTTTCCCAGCGCGGCGCCGGAATGACGCGCCAGATGTTCTGGCGCATCATCAAGCAATACGCACCCAAG
GCAGGAATTCCAGCACAACGGATCTCGCCCCACACGCTGCGACACGCATTTGCCACGCACCTGATCAATCACGGCGCAGA
CCTCCGCGTCGTGCAATTGCTGCTGGGCCACGCCGATATCTCGACGACGCAAATCTACACGCATGTGGCGCGGGAACGCT
TGAAGCAGCTCCACGCCAGACACCATCCGCGCAGCTAA

Upstream 100 bases:

>100_bases
ACGATTCCAGCCGATATTGCTCTGGGGTAGAGCAAGCGGGTCGGCGAGGCCCTCGGGCCTCGCCGCACCCACCTCGTGAT
CACCACGCCACCCCCCGTCC

Downstream 100 bases:

>100_bases
TACACCGACCCGTCACGCGAGCCCATGTCGAAGCAATCGTCCAACACGCCAGAGACACCCGCCACCCAATATCTCCGCCG
CAACGCGGTGCAATTCACCG

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTAFEQQLSAETRAELDLFCDALWLEFGLAANTIAGYRSDLAQFGAWLASRGTQLIEADESQLTAYLAEFSRRAKPASQR
RLMSAWRRFYRGLLGQRRIAQDPTVQLDAPVTGERFPRTLSEAQVESLLAAPDVDTIHGLRDRSMLELLYASGLRVSELV
ELKLFAISTGEGVIRVFGKGSKERLVPTGDIALEWLGRYLREARPALLRGRTCDEVFVSQRGAGMTRQMFWRIIKQYAPK
AGIPAQRISPHTLRHAFATHLINHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHARHHPRS

Sequences:

>Translated_305_residues
MTAFEQQLSAETRAELDLFCDALWLEFGLAANTIAGYRSDLAQFGAWLASRGTQLIEADESQLTAYLAEFSRRAKPASQR
RLMSAWRRFYRGLLGQRRIAQDPTVQLDAPVTGERFPRTLSEAQVESLLAAPDVDTIHGLRDRSMLELLYASGLRVSELV
ELKLFAISTGEGVIRVFGKGSKERLVPTGDIALEWLGRYLREARPALLRGRTCDEVFVSQRGAGMTRQMFWRIIKQYAPK
AGIPAQRISPHTLRHAFATHLINHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHARHHPRS
>Mature_304_residues
TAFEQQLSAETRAELDLFCDALWLEFGLAANTIAGYRSDLAQFGAWLASRGTQLIEADESQLTAYLAEFSRRAKPASQRR
LMSAWRRFYRGLLGQRRIAQDPTVQLDAPVTGERFPRTLSEAQVESLLAAPDVDTIHGLRDRSMLELLYASGLRVSELVE
LKLFAISTGEGVIRVFGKGSKERLVPTGDIALEWLGRYLREARPALLRGRTCDEVFVSQRGAGMTRQMFWRIIKQYAPKA
GIPAQRISPHTLRHAFATHLINHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHARHHPRS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=55.6313993174061, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI1790244, Length=297, Percent_Identity=32.3232323232323, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790768, Length=171, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790767, Length=173, Percent_Identity=31.2138728323699, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34366; Mature: 34235

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFEQQLSAETRAELDLFCDALWLEFGLAANTIAGYRSDLAQFGAWLASRGTQLIEADE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHH
SQLTAYLAEFSRRAKPASQRRLMSAWRRFYRGLLGQRRIAQDPTVQLDAPVTGERFPRTL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHH
SEAQVESLLAAPDVDTIHGLRDRSMLELLYASGLRVSELVELKLFAISTGEGVIRVFGKG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCEEEEECCC
SKERLVPTGDIALEWLGRYLREARPALLRGRTCDEVFVSQRGAGMTRQMFWRIIKQYAPK
CCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCC
AGIPAQRISPHTLRHAFATHLINHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHAR
CCCCHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
HHPRS
CCCCC
>Mature Secondary Structure 
TAFEQQLSAETRAELDLFCDALWLEFGLAANTIAGYRSDLAQFGAWLASRGTQLIEADE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHH
SQLTAYLAEFSRRAKPASQRRLMSAWRRFYRGLLGQRRIAQDPTVQLDAPVTGERFPRTL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHH
SEAQVESLLAAPDVDTIHGLRDRSMLELLYASGLRVSELVELKLFAISTGEGVIRVFGKG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCEEEEECCC
SKERLVPTGDIALEWLGRYLREARPALLRGRTCDEVFVSQRGAGMTRQMFWRIIKQYAPK
CCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCC
AGIPAQRISPHTLRHAFATHLINHGADLRVVQLLLGHADISTTQIYTHVARERLKQLHAR
CCCCHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
HHPRS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]