Click here to switch to the map view.

The map label for this gene is colR [H]

Identifier: 119899448

GI number: 119899448

Start: 3466884

End: 3467567

Strand: Direct

Name: colR [H]

Synonym: azo3158

Alternate gene names: 119899448

Gene position: 3466884-3467567 (Clockwise)

Preceding gene: 119899447

Following gene: 119899449

Centisome position: 79.22

GC content: 66.96

Gene sequence:

>684_bases
ATGAACACGCGCCTGCTGATCGTCGAGGACAACCGCGACATCCTCGCCAACCTGGCCGATTACCTGACGCTGAAAGGCTA
TGAGGTGGATTGCGCGCAGGATGGGCTGACCGGCCTGCACCTCGCCGCCACCCACCATTTCGACCTGATCGTGCTCGACG
TGATGCTGCCCGGCATGGATGGCTTCACGCTGTGCAAGCGCCTGCGCGAAGGCGAACGCAGCGACACGCCCATCATCATG
CTGACGGCGCGCGATGCGCTCGACGACCGCCTGATCGGTTTCTCCGCCGGGGCCGACGACTACCTGACCAAGCCGTTCGC
GCTGTCCGAACTGGTCGCCCGCATCGAGGCCGTGCTCAAGCGCAGCCGCGGTGGCGGCCGGCGGCGGCTGCGCGTGGGTG
ACCTCGACTACGATCTCGATACGCTCGAAGTGACCCGCGCCGGACAAGCGCTGCATCTGGGCCCGATCGGCCTCAAGCTG
CTCGCAGTACTGATGCAGAAGAGCCCGGCGGTGGTCCGCCGCGAAGCGCTCGAAACCGCGCTGTGGGGCGATGAGCCGCC
CGACAGCGACAGCCTGCGCAGCCACATCCACGCCCTGCGGCAACAGATCGACAAGCCCTTCCCGACCCCCCTGCTCCATA
CGGTGCATGGCGTTGGCTTCCGCCTTGCCGCGCATGAGGGTTGA

Upstream 100 bases:

>100_bases
GCGCTGGAGCAGTCGCCGCCGCCGTCAGGCAGTCATTCGCGGCCGCAGCGGCACCGATGCCGCGGGCCACTGAGCAGCGC
CCCCACCTGCTCGCTGCCGC

Downstream 100 bases:

>100_bases
GCGCAGCCTCGCGCGCCGCATCGTCGTCGCGTTCACGCTGATGACCTGCGTCGTCGCCGGGCTCTTTTCCGCCGGTGTCG
TCACCGCGATCAGCCTTGCC

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MNTRLLIVEDNRDILANLADYLTLKGYEVDCAQDGLTGLHLAATHHFDLIVLDVMLPGMDGFTLCKRLREGERSDTPIIM
LTARDALDDRLIGFSAGADDYLTKPFALSELVARIEAVLKRSRGGGRRRLRVGDLDYDLDTLEVTRAGQALHLGPIGLKL
LAVLMQKSPAVVRREALETALWGDEPPDSDSLRSHIHALRQQIDKPFPTPLLHTVHGVGFRLAAHEG

Sequences:

>Translated_227_residues
MNTRLLIVEDNRDILANLADYLTLKGYEVDCAQDGLTGLHLAATHHFDLIVLDVMLPGMDGFTLCKRLREGERSDTPIIM
LTARDALDDRLIGFSAGADDYLTKPFALSELVARIEAVLKRSRGGGRRRLRVGDLDYDLDTLEVTRAGQALHLGPIGLKL
LAVLMQKSPAVVRREALETALWGDEPPDSDSLRSHIHALRQQIDKPFPTPLLHTVHGVGFRLAAHEG
>Mature_227_residues
MNTRLLIVEDNRDILANLADYLTLKGYEVDCAQDGLTGLHLAATHHFDLIVLDVMLPGMDGFTLCKRLREGERSDTPIIM
LTARDALDDRLIGFSAGADDYLTKPFALSELVARIEAVLKRSRGGGRRRLRVGDLDYDLDTLEVTRAGQALHLGPIGLKL
LAVLMQKSPAVVRREALETALWGDEPPDSDSLRSHIHALRQQIDKPFPTPLLHTVHGVGFRLAAHEG

Specific function: Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt, zinc and cadmium homeostasis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=36.036036036036, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=36.7256637168142, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=37.8378378378378, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=37.5, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=35.2422907488987, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=36.1233480176211, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=30.6306306306306, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=35.2678571428571, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.8947368421053, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=34.4827586206897, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=30.4932735426009, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=32.9004329004329, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=38.5321100917431, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788713, Length=86, Percent_Identity=44.1860465116279, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=27.6150627615063, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790299, Length=112, Percent_Identity=32.1428571428571, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI145693157, Length=107, Percent_Identity=33.6448598130841, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25072; Mature: 25072

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRLLIVEDNRDILANLADYLTLKGYEVDCAQDGLTGLHLAATHHFDLIVLDVMLPGMD
CCCEEEEEECCHHHHHHHHHHHEECCCEECHHHCCCCEEEEEECCCHHHEEEEHHHCCCC
GFTLCKRLREGERSDTPIIMLTARDALDDRLIGFSAGADDYLTKPFALSELVARIEAVLK
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHEEECCCCHHHHCCCHHHHHHHHHHHHHHH
RSRGGGRRRLRVGDLDYDLDTLEVTRAGQALHLGPIGLKLLAVLMQKSPAVVRREALETA
HCCCCCCCEEEECCCCCCCCHHHHHCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHH
LWGDEPPDSDSLRSHIHALRQQIDKPFPTPLLHTVHGVGFRLAAHEG
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MNTRLLIVEDNRDILANLADYLTLKGYEVDCAQDGLTGLHLAATHHFDLIVLDVMLPGMD
CCCEEEEEECCHHHHHHHHHHHEECCCEECHHHCCCCEEEEEECCCHHHEEEEHHHCCCC
GFTLCKRLREGERSDTPIIMLTARDALDDRLIGFSAGADDYLTKPFALSELVARIEAVLK
HHHHHHHHHCCCCCCCCEEEEEECCCCCCHHEEECCCCHHHHCCCHHHHHHHHHHHHHHH
RSRGGGRRRLRVGDLDYDLDTLEVTRAGQALHLGPIGLKLLAVLMQKSPAVVRREALETA
HCCCCCCCEEEECCCCCCCCHHHHHCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHH
LWGDEPPDSDSLRSHIHALRQQIDKPFPTPLLHTVHGVGFRLAAHEG
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9044283 [H]