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The map label for this gene is dgk [H]

Identifier: 119899433

GI number: 119899433

Start: 3451005

End: 3451646

Strand: Direct

Name: dgk [H]

Synonym: azo3143

Alternate gene names: 119899433

Gene position: 3451005-3451646 (Clockwise)

Preceding gene: 119899432

Following gene: 119899434

Centisome position: 78.86

GC content: 67.29

Gene sequence:

>642_bases
ATGCTCGACAAGGCCCGCTACATCGTCGTCGAAGGCCCGATCGGGGCTGGCAAGACCTCGCTCGCGCGCCGCCTCGCGGC
CCGCCTGCCGGCCGACACGCTGTTCGAGCAGCCCGAAACCAATCCCTTTCTCGGCCGCTTCTACCAGGGTTCCGACCGCT
GGGCGCTGGCCACCCAGCTCTCCTTCCTGTTCCAGCGTTTCGACCAGCTCGCGGCCCACGCCGCCGACCAGGCCGAAGGC
CGCCGCGTGGTATCCGACTTCGTGCTCGACAAGGACCCGCTGTTCGCGGCGCTCAACCTCGCCGACGACGAGCTGGCCCT
GTACCACCGCATCTTCGACGCAATGAAGCCGCCCGCGCCGCCGGTGCCCGACCTCGTGATCTACCTGCAGGCCAAGCCGG
AGACCCTGGCCGAACGCGTGCGCAAGCGCGGCATGGATGCCGAGCGGCGCATCACCGAGGCCTATCTGGAACGCGTTGCC
GAGCGTTACGCGCGCTTCTTCTACGAATACGACGCAGCGCCGCTCTTCGTCGTCGACGCCGGCGTGCTCAACCCGGTCGA
CCACGACGAGGACTTCGAGCTGCTGCTCGACCGCCTACGCAATATGCGTAGTTATCGGGAATTTTTCGGCTACGCCGGCT
GA

Upstream 100 bases:

>100_bases
GCCGTGCTGTACATGAAGCAGCCGCTCAAGCTTGACTATCTGTGGGCGGGCTTGTGTATGCTGGGCGCGGTCTATTTCAT
CTTCCGCAACTAGGCACACC

Downstream 100 bases:

>100_bases
TCCCTCCTCCGCCTCCCGCCCGCCGCGCCCACTTGTGCGCCGCATCAGTTTGCGGAAAACTCCCGCCTCCCTACGGAGTC
TGCCATGAGCTATCTTCAGG

Product: putative deoxyguanosine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MLDKARYIVVEGPIGAGKTSLARRLAARLPADTLFEQPETNPFLGRFYQGSDRWALATQLSFLFQRFDQLAAHAADQAEG
RRVVSDFVLDKDPLFAALNLADDELALYHRIFDAMKPPAPPVPDLVIYLQAKPETLAERVRKRGMDAERRITEAYLERVA
ERYARFFYEYDAAPLFVVDAGVLNPVDHDEDFELLLDRLRNMRSYREFFGYAG

Sequences:

>Translated_213_residues
MLDKARYIVVEGPIGAGKTSLARRLAARLPADTLFEQPETNPFLGRFYQGSDRWALATQLSFLFQRFDQLAAHAADQAEG
RRVVSDFVLDKDPLFAALNLADDELALYHRIFDAMKPPAPPVPDLVIYLQAKPETLAERVRKRGMDAERRITEAYLERVA
ERYARFFYEYDAAPLFVVDAGVLNPVDHDEDFELLLDRLRNMRSYREFFGYAG
>Mature_213_residues
MLDKARYIVVEGPIGAGKTSLARRLAARLPADTLFEQPETNPFLGRFYQGSDRWALATQLSFLFQRFDQLAAHAADQAEG
RRVVSDFVLDKDPLFAALNLADDELALYHRIFDAMKPPAPPVPDLVIYLQAKPETLAERVRKRGMDAERRITEAYLERVA
ERYARFFYEYDAAPLFVVDAGVLNPVDHDEDFELLLDRLRNMRSYREFFGYAG

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24395; Mature: 24395

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKARYIVVEGPIGAGKTSLARRLAARLPADTLFEQPETNPFLGRFYQGSDRWALATQL
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHCCCCCCHHHHHHH
SFLFQRFDQLAAHAADQAEGRRVVSDFVLDKDPLFAALNLADDELALYHRIFDAMKPPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCHHHHHHHHHHHHHCCCCC
PVPDLVIYLQAKPETLAERVRKRGMDAERRITEAYLERVAERYARFFYEYDAAPLFVVDA
CCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GVLNPVDHDEDFELLLDRLRNMRSYREFFGYAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDKARYIVVEGPIGAGKTSLARRLAARLPADTLFEQPETNPFLGRFYQGSDRWALATQL
CCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHCCCCCCHHHHHHH
SFLFQRFDQLAAHAADQAEGRRVVSDFVLDKDPLFAALNLADDELALYHRIFDAMKPPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCHHHHHHHHHHHHHCCCCC
PVPDLVIYLQAKPETLAERVRKRGMDAERRITEAYLERVAERYARFFYEYDAAPLFVVDA
CCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GVLNPVDHDEDFELLLDRLRNMRSYREFFGYAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]