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The map label for this gene is rsmB [H]

Identifier: 119899412

GI number: 119899412

Start: 3429690

End: 3430982

Strand: Reverse

Name: rsmB [H]

Synonym: azo3122

Alternate gene names: 119899412

Gene position: 3430982-3429690 (Counterclockwise)

Preceding gene: 119899413

Following gene: 119899411

Centisome position: 78.4

GC content: 71.38

Gene sequence:

>1293_bases
ATGCAAAAAAAGACAACCGCTCCCGACGCGCCTTCGCGCGCGCTGCTCATCCAGGCTACCCAGGCGCTCGGCGCCGTACT
GGCCTTCGATCACCCCGCCGATGCGGTGCTGTCGCGCTACTTCCGCGACAACCGTGACCTCGGTCATCGCGACCGCGGCT
TCATCGCCGAAAACATCTACGGCATCGTCCGCCGCCTGCGCTGGCTGCGCCGCCTGGTGGGCGAGAACGCCAGCCCGCGC
CAGCTGCTGCTGGCGTGGCTCGCCCGGGGCGAGGGCTGGCCGATGCGTCAGTTCGAAGGCCTGGTGTCACCCACGGAGCG
CGACTGGGTGGCGGGCATCAAGGCCGCGACGCTGGAAGAGGGCTCGCTGGCCGAACGCGCCGACCTGCCCGACTGGCTGG
CCGAGCGCCTGCTGCGCACCCACGACGAGGCTGCGCTGCTCGCGCTCGCCCACAGCCTCAATCGCCCGGCGCCGCTCGAC
CTGCGGGTGAATGTGGCGAAGGCGGACCGCGACCGCGTGGTCGCCGCGCTGCGTGAAGCCGGCTTTGGCTGCGAGCCGGG
CCGGTGGTCGCCGCAGGCGGTGCGGCTGGCCGGCAAGCCTGCGCTGCAGAAGCATCCGCTGTTCCTCGACGGCAGCGTCG
AGGTGCAGGACGAGGGCAGCCAGCTGCTCGGCCTGCTGGTGCAGCCCAAGCGCGGCGAGCTGGTGGTCGATTTTTGCGCC
GGGGCTGGCGGCAAGACGCTGCAACTGGGCGCGATGATGCGTTCGACCGGGCGGCTCTATGCCTTCGACGTGTCGGAGAA
GCGGCTTGCGAAGCTCAAGCCGCGGATGGCGCGCGCAGGGCTGTCGAACGTCCATCCGGTGCTGATTGCGCACGAGAACG
ACGCCAAGGTGAAACGCCTCGCAGGCAAGGCCGACCGCGTGCTGGTCGATGCGCCCTGCAGCGGGCTCGGCACGCTGCGG
CGCAATCCGGACCTCAAGTGGCGCCAGAGCGCCGCCGCCGTGGATGAGATGGTGGCCAAGCAGGGCGCCATCCTCGCCGC
CGCCGCGCGTCTGGTGAAGCCGGGCGGGCGGCTGGTCTATGCCACCTGCAGCCTGCTGGCCGAAGAGAACGACGAGATCG
TCGATGCCTTCGTGGCCGCCCACCCCGAGTTTCGCCCGGTGGACGCCGAGGCGGTGCTGGCCAGGCAGGGCGTGGCGCTC
GCGACCGGCGCGCGCCTGCGCCTGTCGCCCGCCGAGCACGATACCGACGGCTTCTTCGCCGCGGTGCTCGAACGGACGGG
CGATGCCGGCTGA

Upstream 100 bases:

>100_bases
CAGACGGGACGGCGCCGCGCGCCGGGGGCGAGCCCGAAATGATTGAACTGAAGGAGGAGGTCGACCCCTTGGCCGGTCTC
CAGCAAAACTGAACGGATCC

Downstream 100 bases:

>100_bases
GCGTCGCCGCGCCCTGGGCGCGGTAGCGGCGCTGGCGCTGCTGATCGTGTCCGCGCCGGCGGCCGGTGTCGAAGCCTTTG
CTGCGCGCGGCGAGGTCGAA

Product: hypothetical protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MQKKTTAPDAPSRALLIQATQALGAVLAFDHPADAVLSRYFRDNRDLGHRDRGFIAENIYGIVRRLRWLRRLVGENASPR
QLLLAWLARGEGWPMRQFEGLVSPTERDWVAGIKAATLEEGSLAERADLPDWLAERLLRTHDEAALLALAHSLNRPAPLD
LRVNVAKADRDRVVAALREAGFGCEPGRWSPQAVRLAGKPALQKHPLFLDGSVEVQDEGSQLLGLLVQPKRGELVVDFCA
GAGGKTLQLGAMMRSTGRLYAFDVSEKRLAKLKPRMARAGLSNVHPVLIAHENDAKVKRLAGKADRVLVDAPCSGLGTLR
RNPDLKWRQSAAAVDEMVAKQGAILAAAARLVKPGGRLVYATCSLLAEENDEIVDAFVAAHPEFRPVDAEAVLARQGVAL
ATGARLRLSPAEHDTDGFFAAVLERTGDAG

Sequences:

>Translated_430_residues
MQKKTTAPDAPSRALLIQATQALGAVLAFDHPADAVLSRYFRDNRDLGHRDRGFIAENIYGIVRRLRWLRRLVGENASPR
QLLLAWLARGEGWPMRQFEGLVSPTERDWVAGIKAATLEEGSLAERADLPDWLAERLLRTHDEAALLALAHSLNRPAPLD
LRVNVAKADRDRVVAALREAGFGCEPGRWSPQAVRLAGKPALQKHPLFLDGSVEVQDEGSQLLGLLVQPKRGELVVDFCA
GAGGKTLQLGAMMRSTGRLYAFDVSEKRLAKLKPRMARAGLSNVHPVLIAHENDAKVKRLAGKADRVLVDAPCSGLGTLR
RNPDLKWRQSAAAVDEMVAKQGAILAAAARLVKPGGRLVYATCSLLAEENDEIVDAFVAAHPEFRPVDAEAVLARQGVAL
ATGARLRLSPAEHDTDGFFAAVLERTGDAG
>Mature_430_residues
MQKKTTAPDAPSRALLIQATQALGAVLAFDHPADAVLSRYFRDNRDLGHRDRGFIAENIYGIVRRLRWLRRLVGENASPR
QLLLAWLARGEGWPMRQFEGLVSPTERDWVAGIKAATLEEGSLAERADLPDWLAERLLRTHDEAALLALAHSLNRPAPLD
LRVNVAKADRDRVVAALREAGFGCEPGRWSPQAVRLAGKPALQKHPLFLDGSVEVQDEGSQLLGLLVQPKRGELVVDFCA
GAGGKTLQLGAMMRSTGRLYAFDVSEKRLAKLKPRMARAGLSNVHPVLIAHENDAKVKRLAGKADRVLVDAPCSGLGTLR
RNPDLKWRQSAAAVDEMVAKQGAILAAAARLVKPGGRLVYATCSLLAEENDEIVDAFVAAHPEFRPVDAEAVLARQGVAL
ATGARLRLSPAEHDTDGFFAAVLERTGDAG

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=313, Percent_Identity=28.4345047923323, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI76150623, Length=313, Percent_Identity=28.4345047923323, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI270288818, Length=370, Percent_Identity=30.5405405405405, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI23199998, Length=311, Percent_Identity=31.5112540192926, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI270288816, Length=312, Percent_Identity=30.7692307692308, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI8922322, Length=311, Percent_Identity=31.5112540192926, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI32698918, Length=170, Percent_Identity=30.5882352941176, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI39995082, Length=271, Percent_Identity=25.830258302583, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI301336155, Length=234, Percent_Identity=28.6324786324786, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI2367212, Length=330, Percent_Identity=32.7272727272727, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI87081985, Length=223, Percent_Identity=31.390134529148, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17536757, Length=299, Percent_Identity=27.0903010033445, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25143471, Length=261, Percent_Identity=28.735632183908, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71998419, Length=230, Percent_Identity=30.8695652173913, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534021, Length=230, Percent_Identity=30.8695652173913, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=310, Percent_Identity=26.7741935483871, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319447, Length=180, Percent_Identity=31.6666666666667, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI22024126, Length=308, Percent_Identity=26.9480519480519, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24668781, Length=345, Percent_Identity=28.4057971014493, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21356513, Length=345, Percent_Identity=28.4057971014493, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21356579, Length=247, Percent_Identity=25.9109311740891, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355201, Length=185, Percent_Identity=30.2702702702703, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920494, Length=166, Percent_Identity=32.5301204819277, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46656; Mature: 46656

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKTTAPDAPSRALLIQATQALGAVLAFDHPADAVLSRYFRDNRDLGHRDRGFIAENIY
CCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GIVRRLRWLRRLVGENASPRQLLLAWLARGEGWPMRQFEGLVSPTERDWVAGIKAATLEE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHCCHHEECCC
GSLAERADLPDWLAERLLRTHDEAALLALAHSLNRPAPLDLRVNVAKADRDRVVAALREA
CCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHC
GFGCEPGRWSPQAVRLAGKPALQKHPLFLDGSVEVQDEGSQLLGLLVQPKRGELVVDFCA
CCCCCCCCCCHHHEEECCCCCCCCCCEEECCCEEECCCCCCEEHEEECCCCCCEEEEEEC
GAGGKTLQLGAMMRSTGRLYAFDVSEKRLAKLKPRMARAGLSNVHPVLIAHENDAKVKRL
CCCCCEEEHHHHHHCCCCEEEEECCHHHHHHHCHHHHHCCCCCCCEEEEEECCCHHHHHH
AGKADRVLVDAPCSGLGTLRRNPDLKWRQSAAAVDEMVAKQGAILAAAARLVKPGGRLVY
CCCCCEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
ATCSLLAEENDEIVDAFVAAHPEFRPVDAEAVLARQGVALATGARLRLSPAEHDTDGFFA
EEHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEECCCEEEECCCCCCCCHHHH
AVLERTGDAG
HHHHHCCCCC
>Mature Secondary Structure
MQKKTTAPDAPSRALLIQATQALGAVLAFDHPADAVLSRYFRDNRDLGHRDRGFIAENIY
CCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GIVRRLRWLRRLVGENASPRQLLLAWLARGEGWPMRQFEGLVSPTERDWVAGIKAATLEE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHCCHHEECCC
GSLAERADLPDWLAERLLRTHDEAALLALAHSLNRPAPLDLRVNVAKADRDRVVAALREA
CCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHC
GFGCEPGRWSPQAVRLAGKPALQKHPLFLDGSVEVQDEGSQLLGLLVQPKRGELVVDFCA
CCCCCCCCCCHHHEEECCCCCCCCCCEEECCCEEECCCCCCEEHEEECCCCCCEEEEEEC
GAGGKTLQLGAMMRSTGRLYAFDVSEKRLAKLKPRMARAGLSNVHPVLIAHENDAKVKRL
CCCCCEEEHHHHHHCCCCEEEEECCHHHHHHHCHHHHHCCCCCCCEEEEEECCCHHHHHH
AGKADRVLVDAPCSGLGTLRRNPDLKWRQSAAAVDEMVAKQGAILAAAARLVKPGGRLVY
CCCCCEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
ATCSLLAEENDEIVDAFVAAHPEFRPVDAEAVLARQGVALATGARLRLSPAEHDTDGFFA
EEHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEECCCEEEECCCCCCCCHHHH
AVLERTGDAG
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]