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The map label for this gene is pknB [H]

Identifier: 119899363

GI number: 119899363

Start: 3383307

End: 3384761

Strand: Reverse

Name: pknB [H]

Synonym: azo3073

Alternate gene names: 119899363

Gene position: 3384761-3383307 (Counterclockwise)

Preceding gene: 119899364

Following gene: 119899362

Centisome position: 77.35

GC content: 51.13

Gene sequence:

>1455_bases
ATGGCATGTTTGGCCCGATGGGGTCTAACCCTGCGTGCGAGGCGACCCGCGCGAAAAGCCGCGCAGGCGCCTCAACTCCA
CGTTAGAAATCTACTGGAAACGTTCCACATGAAGCTGAAGCTAATCAAGAAGCTTGGCGATGGTGCATTCGCTGACGTAT
GGCGAGCACTCGATGAACTCGATCGAGAAGTCGCAGTGAAAGTAATCCGTCCTGCCAATGTAGGTGTCGCCGATGCCTTG
GCGCACGCGAAGGCTTTGGCAAGGGCTAGTCATCCAAATGTCGTCGCCGTGCATACGTTGGAGACGATCACCGACCCTGA
TACTGGCGATAGTGTGGATTGCGTCGTGATGGAATTACTACATGGCCACACGTTGTCTGAAAGATTGCAGGGCAACAAGC
TGACGCTACCGGAACTCCACAGTATCGGCACTGGCATTATCAGTGGCCTGCGTCATATCCACAATCAAGGCATGACCCAT
GGTGATCTGCATGAGGAAAATGTGATGATCGTTGGGGATGTCGCTAAGGTGATCGACATCCTTTACCTTGCCTCACTGGC
TGCGCTCACAACCGAGAAGAGAGAGACAAAACTGAAGCGCGACCTGCTTAGCCTTCGACTTCTCTTGCAGTTACTTATCA
AAGACTCAGAACTTGATCCCGCGGAAGCAACTGAGTTCAACAACCTGATCGAAGTTGACGCAGATATCGATGACATAGAA
TTTGCATTTCGGAAGATCGTCACCCCCGAAAACGTGAAAGACAATGCGCGCGTGGTCGAGCACATATTCGCGCGAGTTGC
CGAGGAGGGTTTTGTTGAAGGCCCAGAATATGCGGAGGCGCTCGTTGAGGAAACCCCATCTTCTGCCATGCTTCCGTTGC
TCAAGAGGTTGATTAGCGAAAAGGGCTATGAATCAAAACACAGGGATTACGTCGAATTGGTGTGGTATCAGTTAGCAAAT
GACGAGAAGGTCTTATTCCTTCAGCATCTTGGTGCGTCGATTGATCAAGAGACGCCAAAGGGCAGATATTGGCCGAACCT
CCGCTTGCTGTCCGCTCTAGGGAAGGAGGCTTGGAATGGACTTCCTCTTCGAGTGCGTATTCGACTAGAGGGACTGATCG
TCAAAGATGTTCTTGCTGGACACAAGGATATACATAGCGCCCAGGCGGTATCGGGTGGTTCGCTTGGAACTTACGCTCGG
TCACTGTGGCGACGGTTCAGGAAACCCGAAGATCTTGCCGACAACCTTATTTCCCTGCTGCGCCAGAATTGGTATACGCA
GAATTACGTCGGGGAATACTTTCTTAACAGTGTTCCAGAAATTGCGCGCGTAACAAAACGGCGAGATGAATTTATTAAGG
CCTTACGAGTGGCAGTGGCTAACGATGCTCGGTTGATCGTAAGAAAGATCGACAACTTGCCCGATGACTGGGTGGAGGAA
ATTCAAGGAAACTAA

Upstream 100 bases:

>100_bases
GCCAGAAAAGGAAATCGAGCAACTACATCTCCATCTTGCTCAGGCCGCCAAGCTGCTTCCGCAGGTGCTTACATTATGCG
AACTTCGGGCAAAGACGTGA

Downstream 100 bases:

>100_bases
GAAGTTCTAATAATTGCGTAAACGAGGACGTCAAACTCTTCGCTGCGCTTCGAGTTTGCCGCCTGCTACGCGGATCGTTG
GGCAACTCAATCGGAGGACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MACLARWGLTLRARRPARKAAQAPQLHVRNLLETFHMKLKLIKKLGDGAFADVWRALDELDREVAVKVIRPANVGVADAL
AHAKALARASHPNVVAVHTLETITDPDTGDSVDCVVMELLHGHTLSERLQGNKLTLPELHSIGTGIISGLRHIHNQGMTH
GDLHEENVMIVGDVAKVIDILYLASLAALTTEKRETKLKRDLLSLRLLLQLLIKDSELDPAEATEFNNLIEVDADIDDIE
FAFRKIVTPENVKDNARVVEHIFARVAEEGFVEGPEYAEALVEETPSSAMLPLLKRLISEKGYESKHRDYVELVWYQLAN
DEKVLFLQHLGASIDQETPKGRYWPNLRLLSALGKEAWNGLPLRVRIRLEGLIVKDVLAGHKDIHSAQAVSGGSLGTYAR
SLWRRFRKPEDLADNLISLLRQNWYTQNYVGEYFLNSVPEIARVTKRRDEFIKALRVAVANDARLIVRKIDNLPDDWVEE
IQGN

Sequences:

>Translated_484_residues
MACLARWGLTLRARRPARKAAQAPQLHVRNLLETFHMKLKLIKKLGDGAFADVWRALDELDREVAVKVIRPANVGVADAL
AHAKALARASHPNVVAVHTLETITDPDTGDSVDCVVMELLHGHTLSERLQGNKLTLPELHSIGTGIISGLRHIHNQGMTH
GDLHEENVMIVGDVAKVIDILYLASLAALTTEKRETKLKRDLLSLRLLLQLLIKDSELDPAEATEFNNLIEVDADIDDIE
FAFRKIVTPENVKDNARVVEHIFARVAEEGFVEGPEYAEALVEETPSSAMLPLLKRLISEKGYESKHRDYVELVWYQLAN
DEKVLFLQHLGASIDQETPKGRYWPNLRLLSALGKEAWNGLPLRVRIRLEGLIVKDVLAGHKDIHSAQAVSGGSLGTYAR
SLWRRFRKPEDLADNLISLLRQNWYTQNYVGEYFLNSVPEIARVTKRRDEFIKALRVAVANDARLIVRKIDNLPDDWVEE
IQGN
>Mature_483_residues
ACLARWGLTLRARRPARKAAQAPQLHVRNLLETFHMKLKLIKKLGDGAFADVWRALDELDREVAVKVIRPANVGVADALA
HAKALARASHPNVVAVHTLETITDPDTGDSVDCVVMELLHGHTLSERLQGNKLTLPELHSIGTGIISGLRHIHNQGMTHG
DLHEENVMIVGDVAKVIDILYLASLAALTTEKRETKLKRDLLSLRLLLQLLIKDSELDPAEATEFNNLIEVDADIDDIEF
AFRKIVTPENVKDNARVVEHIFARVAEEGFVEGPEYAEALVEETPSSAMLPLLKRLISEKGYESKHRDYVELVWYQLAND
EKVLFLQHLGASIDQETPKGRYWPNLRLLSALGKEAWNGLPLRVRIRLEGLIVKDVLAGHKDIHSAQAVSGGSLGTYARS
LWRRFRKPEDLADNLISLLRQNWYTQNYVGEYFLNSVPEIARVTKRRDEFIKALRVAVANDARLIVRKIDNLPDDWVEEI
QGN

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI4503787, Length=146, Percent_Identity=28.0821917808219, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17136690, Length=159, Percent_Identity=27.0440251572327, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585924, Length=159, Percent_Identity=27.0440251572327, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR005543
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 54446; Mature: 54315

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACLARWGLTLRARRPARKAAQAPQLHVRNLLETFHMKLKLIKKLGDGAFADVWRALDEL
CCCHHHCCCHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DREVAVKVIRPANVGVADALAHAKALARASHPNVVAVHTLETITDPDTGDSVDCVVMELL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCCCCHHHHHHHHH
HGHTLSERLQGNKLTLPELHSIGTGIISGLRHIHNQGMTHGDLHEENVMIVGDVAKVIDI
HCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHH
LYLASLAALTTEKRETKLKRDLLSLRLLLQLLIKDSELDPAEATEFNNLIEVDADIDDIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEECCCCHHHH
FAFRKIVTPENVKDNARVVEHIFARVAEEGFVEGPEYAEALVEETPSSAMLPLLKRLISE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
KGYESKHRDYVELVWYQLANDEKVLFLQHLGASIDQETPKGRYWPNLRLLSALGKEAWNG
CCCCCHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LPLRVRIRLEGLIVKDVLAGHKDIHSAQAVSGGSLGTYARSLWRRFRKPEDLADNLISLL
CCEEEEEEECHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
RQNWYTQNYVGEYFLNSVPEIARVTKRRDEFIKALRVAVANDARLIVRKIDNLPDDWVEE
HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
IQGN
HCCC
>Mature Secondary Structure 
ACLARWGLTLRARRPARKAAQAPQLHVRNLLETFHMKLKLIKKLGDGAFADVWRALDEL
CCHHHCCCHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DREVAVKVIRPANVGVADALAHAKALARASHPNVVAVHTLETITDPDTGDSVDCVVMELL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCCCCHHHHHHHHH
HGHTLSERLQGNKLTLPELHSIGTGIISGLRHIHNQGMTHGDLHEENVMIVGDVAKVIDI
HCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHH
LYLASLAALTTEKRETKLKRDLLSLRLLLQLLIKDSELDPAEATEFNNLIEVDADIDDIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEECCCCHHHH
FAFRKIVTPENVKDNARVVEHIFARVAEEGFVEGPEYAEALVEETPSSAMLPLLKRLISE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
KGYESKHRDYVELVWYQLANDEKVLFLQHLGASIDQETPKGRYWPNLRLLSALGKEAWNG
CCCCCHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LPLRVRIRLEGLIVKDVLAGHKDIHSAQAVSGGSLGTYARSLWRRFRKPEDLADNLISLL
CCEEEEEEECHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
RQNWYTQNYVGEYFLNSVPEIARVTKRRDEFIKALRVAVANDARLIVRKIDNLPDDWVEE
HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
IQGN
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]