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The map label for this gene is boxD [H]

Identifier: 119899344

GI number: 119899344

Start: 3357353

End: 3358930

Strand: Reverse

Name: boxD [H]

Synonym: azo3054

Alternate gene names: 119899344

Gene position: 3358930-3357353 (Counterclockwise)

Preceding gene: 119899351

Following gene: 119899343

Centisome position: 76.76

GC content: 71.17

Gene sequence:

>1578_bases
GTGAAGCTTGCCAATTACGTATACGGGCAATGGGTGGAAGGCGGCGGCGAGGGGATCGCGCTGCTCGATCCGGTCAATGG
CGAGCACCTGGTCTCGGTGTCCTCGGAAGGTGTGGATGTCGGCCGTGCGCTGAGCTTCGCCCGCGACAGCGGCGGCACTG
CGCTGCGTGCGCTGGGCTACGAGGCCCGCGCCGGCCTGCTCGGCAAGATCGCCGAAGTGCTCACCGCCAACCGCGACGCC
TATTACGACATCTCGCTGCGCAACTCCGGCTCCACCGCCGGCGACATCGCCTTCGATGTCGATGGCGCGATCTTCACCCT
CAAGGCCTACGCCCGCGCCGGCAAGGCCCTTGGCGACGCCCGCCTGCTGAAGGAAGGCGGCCGGGTGGCGCTGGCCAAGA
CCGATGCCTTCCAGGGCCAGCACTTCCTCACCCCGCTGTCGGGCGTCGCGGTGTTCATCAACGCCTTCAATTTCCCGGCC
TGGGGCTTGTGGGAAAAGGCCGCGCCCGCGCTGCTCGCCGGCGTGCCGGTGCTGGTGAAGCCGGCCACCCCCACCGCCTG
GCTGACCCAGCGCATGGTGGCCGACGTGGTTGCCGCCGGCATCCTGCCGCCGGGCGCGCTCAACATCGTCTGTGGCTCCG
CGCGCGATCTGCTCGACCACGTCGGCGAATGCGACGTGGTGTCCTTCACTGGCTCGGCGGACACCGCCGCCCGCATCCGC
ACCCATCCGGCGGTGGTCGCCAGGGCGGTGCGGGTGAATGTGGAGGCCGACAGCGTCAATTCCGCCATCCTCGGCCCCGA
CGCCCAGCCGGGCAGCGCCGAGTTCGATCTCGCGGTGAAGGAGATCGTGCGCGAACTCACCGTCAAGGCCGGGCAGAAAT
GCACCGCCATTCGCCGCATCTTCGCGCCCGCCGCGGTGGCACGCGCGCTGGCCGACGCCGTCGCCGCCAGGCTGGCCGGC
ATGACGGTCGGCAATCCGCGCAGCGAAGGCGTGCGCGTCGGCCCGCTGGTGAGCAAGGCCCAGCAGGCTGCAGCCTTCGA
AGGCCTGGCCAGGCTGCGCCAGGACGCCGAGCTGGTGTTCGGCGGCGGCGAGGGCTTCGTGCCGGTCGATGCCGATCCGG
CCGTTTCCGCCTTCGTCCAGCCCACGCTGCTGTTCTGCGACAAGGGCCTGGCCGCGCAGCATGTGCACGACGTCGAGGTG
TTCGGCCCGGTGGCTACCGTGCTGCCTTATGCCGATACTGCCGAAGTGATCGCGCTCGCCCGCCGCGGCGGCGGTTCGCT
GGTGGCCTCGGTGTATTCCGCCGACGCCGGCTTCCTCGCCGAGCTGGTGCCGGGCATCGCCGAACTGCATGGCCGGGTGA
TGGTGGTGGATGCCGCGATCGGCGGCCAGCACACCGGCCACGGCAACGTGATGCCGACCTGCTTGCACGGCGGGCCGGGC
CGGGCCGGCGGCGGCGAAGAACTGGGCGGCCTGCGCGCGCTCGCGATGTATCACCGGCGTTATGTGGTGCAGGGCGGGCC
GGGGTTGCTGGATGCGCTGTCGGCGGGCGCCGCCGACGCGGCGCTGCTGGGGGCTTGA

Upstream 100 bases:

>100_bases
GTATTCTATATCCAGCAACTGACGAAGCCGATGCAATCCGCTTCACGTCATAGATAGAAGACGCGGCGCAGACCGCAGCA
CAGGTCAACAGGAGGAGCAG

Downstream 100 bases:

>100_bases
TGGTCTTGTCCCTCCCCCTTCAAGGGGGAGGCTAGGAGGGGGATGGGGTTTGGTCTGCTCCCCGCTTACCCCATCCCCAC
CCCAGCCCTCCCCTTGAAGG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MKLANYVYGQWVEGGGEGIALLDPVNGEHLVSVSSEGVDVGRALSFARDSGGTALRALGYEARAGLLGKIAEVLTANRDA
YYDISLRNSGSTAGDIAFDVDGAIFTLKAYARAGKALGDARLLKEGGRVALAKTDAFQGQHFLTPLSGVAVFINAFNFPA
WGLWEKAAPALLAGVPVLVKPATPTAWLTQRMVADVVAAGILPPGALNIVCGSARDLLDHVGECDVVSFTGSADTAARIR
THPAVVARAVRVNVEADSVNSAILGPDAQPGSAEFDLAVKEIVRELTVKAGQKCTAIRRIFAPAAVARALADAVAARLAG
MTVGNPRSEGVRVGPLVSKAQQAAAFEGLARLRQDAELVFGGGEGFVPVDADPAVSAFVQPTLLFCDKGLAAQHVHDVEV
FGPVATVLPYADTAEVIALARRGGGSLVASVYSADAGFLAELVPGIAELHGRVMVVDAAIGGQHTGHGNVMPTCLHGGPG
RAGGGEELGGLRALAMYHRRYVVQGGPGLLDALSAGAADAALLGA

Sequences:

>Translated_525_residues
MKLANYVYGQWVEGGGEGIALLDPVNGEHLVSVSSEGVDVGRALSFARDSGGTALRALGYEARAGLLGKIAEVLTANRDA
YYDISLRNSGSTAGDIAFDVDGAIFTLKAYARAGKALGDARLLKEGGRVALAKTDAFQGQHFLTPLSGVAVFINAFNFPA
WGLWEKAAPALLAGVPVLVKPATPTAWLTQRMVADVVAAGILPPGALNIVCGSARDLLDHVGECDVVSFTGSADTAARIR
THPAVVARAVRVNVEADSVNSAILGPDAQPGSAEFDLAVKEIVRELTVKAGQKCTAIRRIFAPAAVARALADAVAARLAG
MTVGNPRSEGVRVGPLVSKAQQAAAFEGLARLRQDAELVFGGGEGFVPVDADPAVSAFVQPTLLFCDKGLAAQHVHDVEV
FGPVATVLPYADTAEVIALARRGGGSLVASVYSADAGFLAELVPGIAELHGRVMVVDAAIGGQHTGHGNVMPTCLHGGPG
RAGGGEELGGLRALAMYHRRYVVQGGPGLLDALSAGAADAALLGA
>Mature_525_residues
MKLANYVYGQWVEGGGEGIALLDPVNGEHLVSVSSEGVDVGRALSFARDSGGTALRALGYEARAGLLGKIAEVLTANRDA
YYDISLRNSGSTAGDIAFDVDGAIFTLKAYARAGKALGDARLLKEGGRVALAKTDAFQGQHFLTPLSGVAVFINAFNFPA
WGLWEKAAPALLAGVPVLVKPATPTAWLTQRMVADVVAAGILPPGALNIVCGSARDLLDHVGECDVVSFTGSADTAARIR
THPAVVARAVRVNVEADSVNSAILGPDAQPGSAEFDLAVKEIVRELTVKAGQKCTAIRRIFAPAAVARALADAVAARLAG
MTVGNPRSEGVRVGPLVSKAQQAAAFEGLARLRQDAELVFGGGEGFVPVDADPAVSAFVQPTLLFCDKGLAAQHVHDVEV
FGPVATVLPYADTAEVIALARRGGGSLVASVYSADAGFLAELVPGIAELHGRVMVVDAAIGGQHTGHGNVMPTCLHGGPG
RAGGGEELGGLRALAMYHRRYVVQGGPGLLDALSAGAADAALLGA

Specific function: Catalyzes the NADP-dependent oxidation of 3,4- dehydroadipyl-CoA semialdehyde to form cis-3,4-dehydroadipyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=445, Percent_Identity=25.6179775280899, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI21361176, Length=497, Percent_Identity=25.5533199195171, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI25777724, Length=444, Percent_Identity=25.6756756756757, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI115387104, Length=474, Percent_Identity=24.6835443037975, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI153266822, Length=439, Percent_Identity=24.1457858769932, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI25777730, Length=509, Percent_Identity=26.1296660117878, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI25777728, Length=383, Percent_Identity=26.6318537859008, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI25777732, Length=450, Percent_Identity=25.7777777777778, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4507229, Length=420, Percent_Identity=26.4285714285714, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI310128103, Length=362, Percent_Identity=25.9668508287293, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI188035924, Length=362, Percent_Identity=25.9668508287293, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI310128091, Length=299, Percent_Identity=26.4214046822742, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI310128093, Length=299, Percent_Identity=25.752508361204, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI238814322, Length=387, Percent_Identity=23.7726098191214, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI25777721, Length=433, Percent_Identity=26.7898383371824, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI21614513, Length=272, Percent_Identity=26.8382352941176, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI301500698, Length=216, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1787653, Length=516, Percent_Identity=43.9922480620155, Blast_Score=377, Evalue=1e-105,
Organism=Escherichia coli, GI1789015, Length=437, Percent_Identity=26.5446224256293, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787715, Length=487, Percent_Identity=27.7207392197125, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87082295, Length=494, Percent_Identity=25.3036437246964, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI87081896, Length=445, Percent_Identity=27.8651685393258, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786504, Length=443, Percent_Identity=26.6365688487585, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787684, Length=310, Percent_Identity=25.8064516129032, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788042, Length=431, Percent_Identity=27.8422273781903, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787558, Length=440, Percent_Identity=22.7272727272727, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787250, Length=437, Percent_Identity=24.9427917620137, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081926, Length=476, Percent_Identity=23.3193277310924, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17551164, Length=466, Percent_Identity=25.5364806866953, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562198, Length=450, Percent_Identity=24.4444444444444, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25143876, Length=355, Percent_Identity=25.9154929577465, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI25143874, Length=355, Percent_Identity=25.9154929577465, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25144435, Length=434, Percent_Identity=25.8064516129032, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995606, Length=384, Percent_Identity=23.6979166666667, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17534447, Length=357, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995613, Length=382, Percent_Identity=23.8219895287958, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532534, Length=357, Percent_Identity=26.0504201680672, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32564151, Length=312, Percent_Identity=25.9615384615385, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534176, Length=312, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320917, Length=499, Percent_Identity=25.250501002004, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324950, Length=376, Percent_Identity=25.531914893617, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323822, Length=443, Percent_Identity=24.1534988713318, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319478, Length=451, Percent_Identity=22.8381374722838, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323821, Length=440, Percent_Identity=22.5, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325196, Length=418, Percent_Identity=26.555023923445, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650465, Length=495, Percent_Identity=24.6464646464646, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129399, Length=443, Percent_Identity=26.6365688487585, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24585660, Length=457, Percent_Identity=24.0700218818381, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281362580, Length=443, Percent_Identity=24.1534988713318, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI62472918, Length=443, Percent_Identity=24.1534988713318, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI62472926, Length=443, Percent_Identity=24.1534988713318, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI62472936, Length=443, Percent_Identity=24.1534988713318, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356737, Length=443, Percent_Identity=24.1534988713318, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.77 [H]

Molecular weight: Translated: 53737; Mature: 53737

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLANYVYGQWVEGGGEGIALLDPVNGEHLVSVSSEGVDVGRALSFARDSGGTALRALGY
CCCCCCCCCEEECCCCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEECCCC
EARAGLLGKIAEVLTANRDAYYDISLRNSGSTAGDIAFDVDGAIFTLKAYARAGKALGDA
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHH
RLLKEGGRVALAKTDAFQGQHFLTPLSGVAVFINAFNFPAWGLWEKAAPALLAGVPVLVK
HHHHCCCCEEEEECCCCCCCCCCCCHHHHEEEEECCCCCCCCCHHHHCCHHHCCCCEEEE
PATPTAWLTQRMVADVVAAGILPPGALNIVCGSARDLLDHVGECDVVSFTGSADTAARIR
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHCCCCCEEEECCCCCCHHHHH
THPAVVARAVRVNVEADSVNSAILGPDAQPGSAEFDLAVKEIVRELTVKAGQKCTAIRRI
CCHHHHEEEHEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
FAPAAVARALADAVAARLAGMTVGNPRSEGVRVGPLVSKAQQAAAFEGLARLRQDAELVF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCEEEE
GGGEGFVPVDADPAVSAFVQPTLLFCDKGLAAQHVHDVEVFGPVATVLPYADTAEVIALA
ECCCCEEECCCCHHHHHHHCHHHEEECCCCCHHHCCCHHHHCCHHHHCCCCCHHHHHHHH
RRGGGSLVASVYSADAGFLAELVPGIAELHGRVMVVDAAIGGQHTGHGNVMPTCLHGGPG
HCCCCCEEHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEECCCCC
RAGGGEELGGLRALAMYHRRYVVQGGPGLLDALSAGAADAALLGA
CCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCCCHHHCCC
>Mature Secondary Structure
MKLANYVYGQWVEGGGEGIALLDPVNGEHLVSVSSEGVDVGRALSFARDSGGTALRALGY
CCCCCCCCCEEECCCCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEECCCC
EARAGLLGKIAEVLTANRDAYYDISLRNSGSTAGDIAFDVDGAIFTLKAYARAGKALGDA
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHH
RLLKEGGRVALAKTDAFQGQHFLTPLSGVAVFINAFNFPAWGLWEKAAPALLAGVPVLVK
HHHHCCCCEEEEECCCCCCCCCCCCHHHHEEEEECCCCCCCCCHHHHCCHHHCCCCEEEE
PATPTAWLTQRMVADVVAAGILPPGALNIVCGSARDLLDHVGECDVVSFTGSADTAARIR
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHCCCCCEEEECCCCCCHHHHH
THPAVVARAVRVNVEADSVNSAILGPDAQPGSAEFDLAVKEIVRELTVKAGQKCTAIRRI
CCHHHHEEEHEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
FAPAAVARALADAVAARLAGMTVGNPRSEGVRVGPLVSKAQQAAAFEGLARLRQDAELVF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCEEEE
GGGEGFVPVDADPAVSAFVQPTLLFCDKGLAAQHVHDVEVFGPVATVLPYADTAEVIALA
ECCCCEEECCCCHHHHHHHCHHHEEECCCCCHHHCCCHHHHCCHHHHCCCCCHHHHHHHH
RRGGGSLVASVYSADAGFLAELVPGIAELHGRVMVVDAAIGGQHTGHGNVMPTCLHGGPG
HCCCCCEEHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEECCCCC
RAGGGEELGGLRALAMYHRRYVVQGGPGLLDALSAGAADAALLGA
CCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12399500 [H]