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The map label for this gene is hupR [H]

Identifier: 119899257

GI number: 119899257

Start: 3256251

End: 3257171

Strand: Direct

Name: hupR [H]

Synonym: azo2967

Alternate gene names: 119899257

Gene position: 3256251-3257171 (Clockwise)

Preceding gene: 119899252

Following gene: 119899258

Centisome position: 74.41

GC content: 71.99

Gene sequence:

>921_bases
ATGGCCTCACCGATCACCCTCGATGCCCTGCGCGTGCTCGACGCCATCGACCGCAAGCAGAGCTTTGCCGCCGCGGCCGA
AGCCTTGTTCCGCGTGCCTTCCGCGCTGTCCTACACGGTGAGCAAGCTGGAGGAAGACCTCGGCGTGCAGTTGTTCGACC
GCAGCAAGCGCCGCGCGGTGCTGACGCCCGCGGGCCGTCTGGTACTGGAACAGGGCCGCCACATCCTCACCGCCACCGAG
GAACTCACCCGGCTGGTGCAGGCGGTGGGCGACGGCTGGGAGGTGGAGCTGCGCATCGCGGTGGACAGCGTGCTCGACTT
CGCGCCGATCTACGCGCTGGTCGCGGAGTTCCAGACGCTGCAGCACCGCACCGAGCTGCTGCTGAGCGAGGAAGTGCTGG
GCGGCAGCTGGGATGCGCTCAACACCGGGCGCTGCGACCTCGTCATCGGCGCCGCCGGCGAGGCGATTGCGGGCGGCATC
GCCACGCGCGCGCTCGGCGAGGTGGAATTCGTCTTCGCGGTGGCCGCGGGGCATCCGCTGTGCGCGCTGGCGCAGCCGCT
GGCGACCGAGGCGCTGCTCGACTTTCCCACCGTGGTGGTGGCCGACAGCTCGCGCTACCTGCCGGCGCGCTCCACCGGCC
TGCTGGACGGCCGCAGCCGCGTGGTGGTGCCGTCGATCGCCCGCAAGATCGAAGCCCAATGCCTTGGCCTCGGGGTGGGC
TATCTGCCGCGCCACCGCATCGGCGCCGAGCTGGCGGCCGGCACGCTGTGCGAACTCAGCCTGGAAAAGGCCCATCCGCC
GCAGGCGCTGTCGATCGCCTGGCGCAGCGCCGCGCGCGGCAAGGCGCTGCGCTGGTTCCTCGACCGCCTGGCCGCGCTGC
GCTTCGACAGCCGCGCCGGCCTCGTGCCGGTTTCGGGCTGA

Upstream 100 bases:

>100_bases
TTTTTTGATCAGTCTCGGTGACTGGTGAGCGAATGATAGGTAGCGGCATCCGAAAAAAATAACGGACAATATCGACCATT
AAGTTCAAACCGTTTGAACA

Downstream 100 bases:

>100_bases
AATACGCCGCGTGTCGCGGTCCGTCGCGGTGGTCTAGGCTGAAGCCACGCCGGTGCCGCCCGCGGTCACCGCAGCGCACC
GGCCTTCGTCCCTTACCCAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MASPITLDALRVLDAIDRKQSFAAAAEALFRVPSALSYTVSKLEEDLGVQLFDRSKRRAVLTPAGRLVLEQGRHILTATE
ELTRLVQAVGDGWEVELRIAVDSVLDFAPIYALVAEFQTLQHRTELLLSEEVLGGSWDALNTGRCDLVIGAAGEAIAGGI
ATRALGEVEFVFAVAAGHPLCALAQPLATEALLDFPTVVVADSSRYLPARSTGLLDGRSRVVVPSIARKIEAQCLGLGVG
YLPRHRIGAELAAGTLCELSLEKAHPPQALSIAWRSAARGKALRWFLDRLAALRFDSRAGLVPVSG

Sequences:

>Translated_306_residues
MASPITLDALRVLDAIDRKQSFAAAAEALFRVPSALSYTVSKLEEDLGVQLFDRSKRRAVLTPAGRLVLEQGRHILTATE
ELTRLVQAVGDGWEVELRIAVDSVLDFAPIYALVAEFQTLQHRTELLLSEEVLGGSWDALNTGRCDLVIGAAGEAIAGGI
ATRALGEVEFVFAVAAGHPLCALAQPLATEALLDFPTVVVADSSRYLPARSTGLLDGRSRVVVPSIARKIEAQCLGLGVG
YLPRHRIGAELAAGTLCELSLEKAHPPQALSIAWRSAARGKALRWFLDRLAALRFDSRAGLVPVSG
>Mature_305_residues
ASPITLDALRVLDAIDRKQSFAAAAEALFRVPSALSYTVSKLEEDLGVQLFDRSKRRAVLTPAGRLVLEQGRHILTATEE
LTRLVQAVGDGWEVELRIAVDSVLDFAPIYALVAEFQTLQHRTELLLSEEVLGGSWDALNTGRCDLVIGAAGEAIAGGIA
TRALGEVEFVFAVAAGHPLCALAQPLATEALLDFPTVVVADSSRYLPARSTGLLDGRSRVVVPSIARKIEAQCLGLGVGY
LPRHRIGAELAAGTLCELSLEKAHPPQALSIAWRSAARGKALRWFLDRLAALRFDSRAGLVPVSG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082024, Length=287, Percent_Identity=38.6759581881533, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787949, Length=283, Percent_Identity=38.1625441696113, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1789492, Length=290, Percent_Identity=37.9310344827586, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1786713, Length=279, Percent_Identity=34.0501792114695, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786508, Length=298, Percent_Identity=28.1879194630872, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790262, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32706; Mature: 32575

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPITLDALRVLDAIDRKQSFAAAAEALFRVPSALSYTVSKLEEDLGVQLFDRSKRRAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCCCEE
LTPAGRLVLEQGRHILTATEELTRLVQAVGDGWEVELRIAVDSVLDFAPIYALVAEFQTL
ECCHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHH
QHRTELLLSEEVLGGSWDALNTGRCDLVIGAAGEAIAGGIATRALGEVEFVFAVAAGHPL
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCH
CALAQPLATEALLDFPTVVVADSSRYLPARSTGLLDGRSRVVVPSIARKIEAQCLGLGVG
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCC
YLPRHRIGAELAAGTLCELSLEKAHPPQALSIAWRSAARGKALRWFLDRLAALRFDSRAG
CCCCHHHCHHHHHCHHHEEEHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
LVPVSG
EEECCC
>Mature Secondary Structure 
ASPITLDALRVLDAIDRKQSFAAAAEALFRVPSALSYTVSKLEEDLGVQLFDRSKRRAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCCCEE
LTPAGRLVLEQGRHILTATEELTRLVQAVGDGWEVELRIAVDSVLDFAPIYALVAEFQTL
ECCHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHH
QHRTELLLSEEVLGGSWDALNTGRCDLVIGAAGEAIAGGIATRALGEVEFVFAVAAGHPL
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCH
CALAQPLATEALLDFPTVVVADSSRYLPARSTGLLDGRSRVVVPSIARKIEAQCLGLGVG
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCC
YLPRHRIGAELAAGTLCELSLEKAHPPQALSIAWRSAARGKALRWFLDRLAALRFDSRAG
CCCCHHHCHHHHHCHHHEEEHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
LVPVSG
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]