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The map label for this gene is sigZ [H]

Identifier: 119899252

GI number: 119899252

Start: 3251919

End: 3252485

Strand: Direct

Name: sigZ [H]

Synonym: azo2962

Alternate gene names: 119899252

Gene position: 3251919-3252485 (Clockwise)

Preceding gene: 119899251

Following gene: 119899257

Centisome position: 74.31

GC content: 69.14

Gene sequence:

>567_bases
ATGTCCCCGACTTCTCCGGGCGCGGTCGACACCGTGCTGGCCGAAATGGCCCAACCCGTGCTGCGCTACCTGCAGCGCTT
CGTCGGCGACGCCGCGATTGCGCGCGACCTGCAGCAGGAAACCCTGATCCGCATCGCGCGCGGCTACGACAGCTTCGGCG
CCCGCTCGTCGGTCAAGACCTGGGCCTTCGCGATCGCCAACCGGGTGGCGGCGGACTACTACCGCGCGCCGGCCCACCGC
ATGCAGATCGTCGATCTGGACGAGGCGGAAGAAGTCGCCAGCGGCGAGGCGGCGATCGACACCCGGCTGGTCGAAGAAGA
GATGAACCGCTGCGTGCGGCAGGTCATCGACAGCCTGCCCGACACCTACCGCGCGGCGCTGATCCTGCACGACCTGGAAG
GCCTGTCGATCGAGCAGACCGCGCTGATCTGCGAGTGCACGCTGGCCACCGCCAAGATCCGCATCCACCGTGCCCGCCAC
CGCCTGCGCGAGGCGCTGGGCAGGCAGTGCGCCTTCTACCACGACGACCAGGGCGTTTATCGCTGCGACCGCAACACCCC
GGCCTGA

Upstream 100 bases:

>100_bases
GCGTCATCGCCCTGGCGTATCGCCAGCCCGGCCTGCGCGAAGCGATCCTTTATTCCGGTCTCGGCTTATGCTGAGGTCCG
CATCCACTCGAGGCGCATCC

Downstream 100 bases:

>100_bases
CGCGCCGCTAGCCGAGCAGCTTCACCGCCAGCCCCACCAGCGCGCACCCGCCGATCACGTGGATGACGTTGGCCTTGAAG
CGGAACAGCGCCAGCGCCGC

Product: putative RNA polymerase sigma factor SigZ

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSPTSPGAVDTVLAEMAQPVLRYLQRFVGDAAIARDLQQETLIRIARGYDSFGARSSVKTWAFAIANRVAADYYRAPAHR
MQIVDLDEAEEVASGEAAIDTRLVEEEMNRCVRQVIDSLPDTYRAALILHDLEGLSIEQTALICECTLATAKIRIHRARH
RLREALGRQCAFYHDDQGVYRCDRNTPA

Sequences:

>Translated_188_residues
MSPTSPGAVDTVLAEMAQPVLRYLQRFVGDAAIARDLQQETLIRIARGYDSFGARSSVKTWAFAIANRVAADYYRAPAHR
MQIVDLDEAEEVASGEAAIDTRLVEEEMNRCVRQVIDSLPDTYRAALILHDLEGLSIEQTALICECTLATAKIRIHRARH
RLREALGRQCAFYHDDQGVYRCDRNTPA
>Mature_187_residues
SPTSPGAVDTVLAEMAQPVLRYLQRFVGDAAIARDLQQETLIRIARGYDSFGARSSVKTWAFAIANRVAADYYRAPAHRM
QIVDLDEAEEVASGEAAIDTRLVEEEMNRCVRQVIDSLPDTYRAALILHDLEGLSIEQTALICECTLATAKIRIHRARHR
LREALGRQCAFYHDDQGVYRCDRNTPA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=160, Percent_Identity=33.125, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21078; Mature: 20947

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTSPGAVDTVLAEMAQPVLRYLQRFVGDAAIARDLQQETLIRIARGYDSFGARSSVKT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
WAFAIANRVAADYYRAPAHRMQIVDLDEAEEVASGEAAIDTRLVEEEMNRCVRQVIDSLP
HHHHHHHHHHHHHHHCCHHHEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
DTYRAALILHDLEGLSIEQTALICECTLATAKIRIHRARHRLREALGRQCAFYHDDQGVY
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCE
RCDRNTPA
ECCCCCCC
>Mature Secondary Structure 
SPTSPGAVDTVLAEMAQPVLRYLQRFVGDAAIARDLQQETLIRIARGYDSFGARSSVKT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
WAFAIANRVAADYYRAPAHRMQIVDLDEAEEVASGEAAIDTRLVEEEMNRCVRQVIDSLP
HHHHHHHHHHHHHHHCCHHHEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
DTYRAALILHDLEGLSIEQTALICECTLATAKIRIHRARHRLREALGRQCAFYHDDQGVY
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCE
RCDRNTPA
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]