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The map label for this gene is pdxA

Identifier: 119899175

GI number: 119899175

Start: 3165517

End: 3166509

Strand: Reverse

Name: pdxA

Synonym: azo2885

Alternate gene names: 119899175

Gene position: 3166509-3165517 (Counterclockwise)

Preceding gene: 119899176

Following gene: 119899174

Centisome position: 72.36

GC content: 72.81

Gene sequence:

>993_bases
ATGGCCGCGCTTCCGGTCCTGGCCGTCACCAGCGGCGAACCCGCCGGCGTCGGGCCCGAACTGTGCGCGCGGCTGCTTGC
GCGCGACTGGCCGGCGCGACTGGTCGTGCTGGGCGACGCCGACCTCATCGCCGCGCGCGCTGCGGCGGTGGGCAGCCCGA
TAGCGGTCCGGCACTACAGCCGCGGCCAGGCCCAGGCCGCCGGCGTGCTCGAGGTGCTCCACATTCCACTCGCCGAACCG
AGCGATGCGGGTCGCCTGGCGGTGGGCAACGCGCGCTACGTGCTGGCGCTGCTCGACCGTGCGCTCGCCGGCTGCGTCGG
CGGCGAGTTTGCCGGCATGGTCACCGCGCCGGTGCACAAGGGCGTGATCTGCGAGTCCGGTATCGCGTTCTCCGGTCATA
CCGAATATCTCGCCGAACATACCGCGACGCCGCTGGTCGTGATGATGCTGGTCGGCGGCGGCATGCGCGTCGCGCTCGCC
ACCACGCATCTGCCACTGGCCGCGGTGTCGGCGGCGATCACGCGGCCGGTGCTCGAACAGACGCTGCGCATCCTTCACGC
CGACCTGGTGCAACGCTTCGGCATCGCCGCACCCCGCATCCTGGTGGCGGGCCTCAACCCGCACGCGGGCGAGGGTGGTC
ACATGGGGCGCGAGGAAATCGAGGTCATCACCCCGGTACTGGACCGCCTGCGCGCCGAAGGCCTGCAACTCGTCGGCCCG
CTGCCGGCCGACACCCTGTTCGCGCCGCACACGCTGGCGCACGGCGACGCGGTGCTGGCGATGTATCACGACCAGGGCCT
GCCGGTGCTCAAGCACGCCAGCTTCGGCGGCGGCGTCAACGTCACGCTCGGTCTGCCGGTGATCCGCACTTCGGTCGACC
ACGGCACGGCGCTCGACCTTGCCGGCAGCGGTCGCGCCGACCCCGGCAGCCTGTACGCCGCGGTCGAGCTGGCCGTGTCG
ATGGCCGAGGCCCGTGCCCGCCAGCCGCGCTGA

Upstream 100 bases:

>100_bases
ATCCTGCGCGAACGCAAGGCCGAAGAGGCCTACGAGGACTGGGTGCGCCAGCTGCGCGACAGCACCTACGTCGAATACCG
CCTCGAAAACGACTGATCCC

Downstream 100 bases:

>100_bases
GCGGCGTTCGAGGAATTTCATGCAAGACCGCGAAACCGACGGCCACCGCGCCAGAAAGCGCTTCGGCCAGAACTTCCTGT
CCGACCCCAACATCATCCGC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MAALPVLAVTSGEPAGVGPELCARLLARDWPARLVVLGDADLIAARAAAVGSPIAVRHYSRGQAQAAGVLEVLHIPLAEP
SDAGRLAVGNARYVLALLDRALAGCVGGEFAGMVTAPVHKGVICESGIAFSGHTEYLAEHTATPLVVMMLVGGGMRVALA
TTHLPLAAVSAAITRPVLEQTLRILHADLVQRFGIAAPRILVAGLNPHAGEGGHMGREEIEVITPVLDRLRAEGLQLVGP
LPADTLFAPHTLAHGDAVLAMYHDQGLPVLKHASFGGGVNVTLGLPVIRTSVDHGTALDLAGSGRADPGSLYAAVELAVS
MAEARARQPR

Sequences:

>Translated_330_residues
MAALPVLAVTSGEPAGVGPELCARLLARDWPARLVVLGDADLIAARAAAVGSPIAVRHYSRGQAQAAGVLEVLHIPLAEP
SDAGRLAVGNARYVLALLDRALAGCVGGEFAGMVTAPVHKGVICESGIAFSGHTEYLAEHTATPLVVMMLVGGGMRVALA
TTHLPLAAVSAAITRPVLEQTLRILHADLVQRFGIAAPRILVAGLNPHAGEGGHMGREEIEVITPVLDRLRAEGLQLVGP
LPADTLFAPHTLAHGDAVLAMYHDQGLPVLKHASFGGGVNVTLGLPVIRTSVDHGTALDLAGSGRADPGSLYAAVELAVS
MAEARARQPR
>Mature_329_residues
AALPVLAVTSGEPAGVGPELCARLLARDWPARLVVLGDADLIAARAAAVGSPIAVRHYSRGQAQAAGVLEVLHIPLAEPS
DAGRLAVGNARYVLALLDRALAGCVGGEFAGMVTAPVHKGVICESGIAFSGHTEYLAEHTATPLVVMMLVGGGMRVALAT
THLPLAAVSAAITRPVLEQTLRILHADLVQRFGIAAPRILVAGLNPHAGEGGHMGREEIEVITPVLDRLRAEGLQLVGPL
PADTLFAPHTLAHGDAVLAMYHDQGLPVLKHASFGGGVNVTLGLPVIRTSVDHGTALDLAGSGRADPGSLYAAVELAVSM
AEARARQPR

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family

Homologues:

Organism=Escherichia coli, GI1786237, Length=318, Percent_Identity=58.8050314465409, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXA_AZOSB (A1K9J6)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934388.1
- ProteinModelPortal:   A1K9J6
- SMR:   A1K9J6
- STRING:   A1K9J6
- GeneID:   4609107
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2885
- eggNOG:   COG1995
- HOGENOM:   HBG451136
- OMA:   NPANAAY
- PhylomeDB:   A1K9J6
- ProtClustDB:   PRK00232
- BioCyc:   ASP62928:AZO2885-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00536
- InterPro:   IPR005255
- TIGRFAMs:   TIGR00557

Pfam domain/function: PF04166 PdxA

EC number: =1.1.1.262

Molecular weight: Translated: 33929; Mature: 33798

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: BINDING 133-133 BINDING 134-134 BINDING 271-271 BINDING 280-280 BINDING 289-289

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALPVLAVTSGEPAGVGPELCARLLARDWPARLVVLGDADLIAARAAAVGSPIAVRHYS
CCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECC
RGQAQAAGVLEVLHIPLAEPSDAGRLAVGNARYVLALLDRALAGCVGGEFAGMVTAPVHK
CCCHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
GVICESGIAFSGHTEYLAEHTATPLVVMMLVGGGMRVALATTHLPLAAVSAAITRPVLEQ
CEEECCCCEECCCHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHH
TLRILHADLVQRFGIAAPRILVAGLNPHAGEGGHMGREEIEVITPVLDRLRAEGLQLVGP
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECC
LPADTLFAPHTLAHGDAVLAMYHDQGLPVLKHASFGGGVNVTLGLPVIRTSVDHGTALDL
CCCCCCCCCCEECCCCEEEEEEECCCCCEEEECCCCCCEEEEECCCEEEECCCCCCEEEE
AGSGRADPGSLYAAVELAVSMAEARARQPR
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AALPVLAVTSGEPAGVGPELCARLLARDWPARLVVLGDADLIAARAAAVGSPIAVRHYS
CCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECC
RGQAQAAGVLEVLHIPLAEPSDAGRLAVGNARYVLALLDRALAGCVGGEFAGMVTAPVHK
CCCHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
GVICESGIAFSGHTEYLAEHTATPLVVMMLVGGGMRVALATTHLPLAAVSAAITRPVLEQ
CEEECCCCEECCCHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHH
TLRILHADLVQRFGIAAPRILVAGLNPHAGEGGHMGREEIEVITPVLDRLRAEGLQLVGP
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECC
LPADTLFAPHTLAHGDAVLAMYHDQGLPVLKHASFGGGVNVTLGLPVIRTSVDHGTALDL
CCCCCCCCCCEECCCCEEEEEEECCCCCEEEECCCCCCEEEEECCCEEEECCCCCCEEEE
AGSGRADPGSLYAAVELAVSMAEARARQPR
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA