Click here to switch to the map view.

The map label for this gene is gpsA [H]

Identifier: 119899104

GI number: 119899104

Start: 3094335

End: 3095324

Strand: Direct

Name: gpsA [H]

Synonym: azo2814

Alternate gene names: 119899104

Gene position: 3094335-3095324 (Clockwise)

Preceding gene: 119899103

Following gene: 119899107

Centisome position: 70.71

GC content: 71.11

Gene sequence:

>990_bases
TTGAAGCGGCTGAAGATCGCGGTCCTTGGCGCCGGCGCCTGGGGCACGGCACTCGCCCAGGCCTTCGCCGATACGCACGA
GGCGGTGCTGTGGGGGCGTGACGCGGCGCATATCGACGCCACCCGGCATGCGGCGGAAAACACCCGCTACCTGCCCGGTG
TCGCACTGCATCCGCAACTCGCCCTCACCGCCGACTTGCCCGCGGCGGCGCTCGGTGCCGACCTGCACCTGGTGGTCACG
CCGCTGGCCGGCCTGCGCGACACGCTGCGGCTGCTCAACGACATCCAGCCGGATACCCCGGTCATCTGGGCCTGCAAGGG
CCTCGAAGCGGGCAGCGGCAAGCTCCCGCACGAAATCGTCGCCGACGAGCTGGGCGCCACGCCCTGCGGCGTCCTCACCG
GTCCGAGTTTCGCAGCCGAAGTGGCCCGTGGCCTGCCGGCCGCGATCACCCTTGCCGCCAGCGACGTCGAGTTCGCGCGC
CACTGGGTGCATGCGCTGCACCGTCCGCGCCTGCGGCTGTACGCCAACGCCGACGTGGTCGGATGCGAAATCGGCGGTGC
GCTCAAGAACGTCATGGCGATTGCCGCCGGCGTTTCGGACGGCATGGGCTTCGGCCTCAACGCACGCGCGGCCCTGATCA
CCCGCGGCCTGGCGGAAATCGCCCGTCTCGCCACCGCCATGGGCGGACACGCCGAGACCCTGATGGGACTCGCCGGCATG
GGCGACCTGATCCTCACCTGCACCGGCGACCTCTCACGCAACCGGCGGGTGGGTCTGGCACTGGCCGCCGGAAACACGCT
GTCCGACATCCTGCGCGACCTCGGTCATGTCGCCGAAGGCGTCTCCACCGCGCACGAGGCTGTCCGTCTCGCCCGCCGCC
ACGGTGTGGAAATGCCGATCTGCGAAGCCGTGGATGCGCTGCTGCATGGCGGCCTGGCCGCGCGCGACGCGGTCGAGCGC
CTGCTCGCACGCGACCCCAAGCGGGAATAA

Upstream 100 bases:

>100_bases
TCGTGCTCGAACACGCGGCTGCCCCGGCCGACGGCTGGGTCAGGGTCCGCCACCCCGATGGCGCCAGCGGTTTCGTGCGC
GTCACCGAGGTCTGGGGCCT

Downstream 100 bases:

>100_bases
GCGCGCGCCCCCCTTCAGAGTTCGACGGGCAGGCTTTGCGGCCCGTCTCCTGCGCCGACGAAGTCCTGCTGCCGCCACGC
TTCGAACACCATCACCGCCA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKRLKIAVLGAGAWGTALAQAFADTHEAVLWGRDAAHIDATRHAAENTRYLPGVALHPQLALTADLPAAALGADLHLVVT
PLAGLRDTLRLLNDIQPDTPVIWACKGLEAGSGKLPHEIVADELGATPCGVLTGPSFAAEVARGLPAAITLAASDVEFAR
HWVHALHRPRLRLYANADVVGCEIGGALKNVMAIAAGVSDGMGFGLNARAALITRGLAEIARLATAMGGHAETLMGLAGM
GDLILTCTGDLSRNRRVGLALAAGNTLSDILRDLGHVAEGVSTAHEAVRLARRHGVEMPICEAVDALLHGGLAARDAVER
LLARDPKRE

Sequences:

>Translated_329_residues
MKRLKIAVLGAGAWGTALAQAFADTHEAVLWGRDAAHIDATRHAAENTRYLPGVALHPQLALTADLPAAALGADLHLVVT
PLAGLRDTLRLLNDIQPDTPVIWACKGLEAGSGKLPHEIVADELGATPCGVLTGPSFAAEVARGLPAAITLAASDVEFAR
HWVHALHRPRLRLYANADVVGCEIGGALKNVMAIAAGVSDGMGFGLNARAALITRGLAEIARLATAMGGHAETLMGLAGM
GDLILTCTGDLSRNRRVGLALAAGNTLSDILRDLGHVAEGVSTAHEAVRLARRHGVEMPICEAVDALLHGGLAARDAVER
LLARDPKRE
>Mature_329_residues
MKRLKIAVLGAGAWGTALAQAFADTHEAVLWGRDAAHIDATRHAAENTRYLPGVALHPQLALTADLPAAALGADLHLVVT
PLAGLRDTLRLLNDIQPDTPVIWACKGLEAGSGKLPHEIVADELGATPCGVLTGPSFAAEVARGLPAAITLAASDVEFAR
HWVHALHRPRLRLYANADVVGCEIGGALKNVMAIAAGVSDGMGFGLNARAALITRGLAEIARLATAMGGHAETLMGLAGM
GDLILTCTGDLSRNRRVGLALAAGNTLSDILRDLGHVAEGVSTAHEAVRLARRHGVEMPICEAVDALLHGGLAARDAVER
LLARDPKRE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=339, Percent_Identity=30.3834808259587, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24307999, Length=335, Percent_Identity=30.4477611940298, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1790037, Length=329, Percent_Identity=45.2887537993921, Blast_Score=262, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI32564399, Length=349, Percent_Identity=28.9398280802292, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI193210136, Length=358, Percent_Identity=28.2122905027933, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32564403, Length=358, Percent_Identity=28.2122905027933, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17507425, Length=343, Percent_Identity=27.9883381924198, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193210134, Length=345, Percent_Identity=26.0869565217391, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324513, Length=358, Percent_Identity=31.2849162011173, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320181, Length=362, Percent_Identity=30.1104972375691, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17136200, Length=343, Percent_Identity=28.8629737609329, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136202, Length=343, Percent_Identity=28.8629737609329, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136204, Length=343, Percent_Identity=28.8629737609329, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI22026922, Length=348, Percent_Identity=26.4367816091954, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281362270, Length=242, Percent_Identity=32.6446280991736, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI45551945, Length=242, Percent_Identity=32.6446280991736, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24648969, Length=197, Percent_Identity=34.010152284264, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 34208; Mature: 34208

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLKIAVLGAGAWGTALAQAFADTHEAVLWGRDAAHIDATRHAAENTRYLPGVALHPQL
CCCEEEEEEECCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCCCCEEECCCE
ALTADLPAAALGADLHLVVTPLAGLRDTLRLLNDIQPDTPVIWACKGLEAGSGKLPHEIV
EEECCCCHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHH
ADELGATPCGVLTGPSFAAEVARGLPAAITLAASDVEFARHWVHALHRPRLRLYANADVV
HHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCEE
GCEIGGALKNVMAIAAGVSDGMGFGLNARAALITRGLAEIARLATAMGGHAETLMGLAGM
EEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
GDLILTCTGDLSRNRRVGLALAAGNTLSDILRDLGHVAEGVSTAHEAVRLARRHGVEMPI
CCEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
CEAVDALLHGGLAARDAVERLLARDPKRE
HHHHHHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKRLKIAVLGAGAWGTALAQAFADTHEAVLWGRDAAHIDATRHAAENTRYLPGVALHPQL
CCCEEEEEEECCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCCCCEEECCCE
ALTADLPAAALGADLHLVVTPLAGLRDTLRLLNDIQPDTPVIWACKGLEAGSGKLPHEIV
EEECCCCHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHH
ADELGATPCGVLTGPSFAAEVARGLPAAITLAASDVEFARHWVHALHRPRLRLYANADVV
HHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCEE
GCEIGGALKNVMAIAAGVSDGMGFGLNARAALITRGLAEIARLATAMGGHAETLMGLAGM
EEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
GDLILTCTGDLSRNRRVGLALAAGNTLSDILRDLGHVAEGVSTAHEAVRLARRHGVEMPI
CCEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
CEAVDALLHGGLAARDAVERLLARDPKRE
HHHHHHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA