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The map label for this gene is gpmA

Identifier: 119899098

GI number: 119899098

Start: 3091417

End: 3092166

Strand: Reverse

Name: gpmA

Synonym: azo2808

Alternate gene names: 119899098

Gene position: 3092166-3091417 (Counterclockwise)

Preceding gene: 119899105

Following gene: 119899097

Centisome position: 70.66

GC content: 65.47

Gene sequence:

>750_bases
ATGTACAAGATCGTCCTGCTTCGCCACGGTGAATCCACCTGGAACAAGGAAAACCGCTTCACCGGCTGGACCGACGTCGA
CCTCACCGAACTCGGGGTGGGCGAGGCCCGCGCGGCGGGCCAGTTGCTCAAGCGCGAAGGCTACAGCTTCGATCTCGCCT
TCACGTCGGTGCTCAAGCGCGCCAACAAGACGCTGAACATCGTGCTCGAGGAACTCGACGCGCTGTGGCTGCCGGTCGAG
CATTCGTGGCGCCTGAACGAACGCCACTACGGCGCGCTGCAGGGCCTGAACAAGGCCGAGACTGCAGCCAAGTTCGGCGA
CGACCAGGTGCTGGTGTGGCGCCGTTCCTACGACATCCCGCCGCCGGCGCTGGAAGAAGGCGACGAGCGTCTGAACTATG
ACGATCCGCGCTACGGTTCGCTGCCGCGCGCGCGCTTCCCGCGCACCGAATGCCTGGCCGACACCGTGGCTCGCGTGGTG
CCGTACTGGGAAACCGTGATCGTGCCGCAGATCCTCTCCGGCCGCCGGATCCTGATCGCGGCGCACGGCAACAGCCTGCG
CGCCCTCATCAAGTACCTCGATGGCATTTCCGACGGTGACATCGTCGGGCTCAATATTCCCACGGCGCAGCCGCTGGTCT
ATGAGCTTGACGTGAACCTCAAGCCGGTCAAGAGCTACTACCTCGCCGACGAGGACACCATCCGCGCGGCTCAGGCCGCC
GTGGCCGGGCAGGGCAAGGCAAAGGGCTGA

Upstream 100 bases:

>100_bases
TGTCTCTTGCTCGCCTTGGGCAGGCGCATGATTTTGCCATGCGCGCGGCAGCGTGCTGTGCCCAGGCCTTCGTTCATCAT
TCAACCGGATCCGATTTCCC

Downstream 100 bases:

>100_bases
CGCGGACCGGAACCTTCCTCCCATGTTGCACCTGCGGCGCTCCGCCGCGCTCGGCCTGGCGGCGCTGCTGGTGGTGGCGT
CGCCCCAGCAGCCCGTGCGG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MYKIVLLRHGESTWNKENRFTGWTDVDLTELGVGEARAAGQLLKREGYSFDLAFTSVLKRANKTLNIVLEELDALWLPVE
HSWRLNERHYGALQGLNKAETAAKFGDDQVLVWRRSYDIPPPALEEGDERLNYDDPRYGSLPRARFPRTECLADTVARVV
PYWETVIVPQILSGRRILIAAHGNSLRALIKYLDGISDGDIVGLNIPTAQPLVYELDVNLKPVKSYYLADEDTIRAAQAA
VAGQGKAKG

Sequences:

>Translated_249_residues
MYKIVLLRHGESTWNKENRFTGWTDVDLTELGVGEARAAGQLLKREGYSFDLAFTSVLKRANKTLNIVLEELDALWLPVE
HSWRLNERHYGALQGLNKAETAAKFGDDQVLVWRRSYDIPPPALEEGDERLNYDDPRYGSLPRARFPRTECLADTVARVV
PYWETVIVPQILSGRRILIAAHGNSLRALIKYLDGISDGDIVGLNIPTAQPLVYELDVNLKPVKSYYLADEDTIRAAQAA
VAGQGKAKG
>Mature_249_residues
MYKIVLLRHGESTWNKENRFTGWTDVDLTELGVGEARAAGQLLKREGYSFDLAFTSVLKRANKTLNIVLEELDALWLPVE
HSWRLNERHYGALQGLNKAETAAKFGDDQVLVWRRSYDIPPPALEEGDERLNYDDPRYGSLPRARFPRTECLADTVARVV
PYWETVIVPQILSGRRILIAAHGNSLRALIKYLDGISDGDIVGLNIPTAQPLVYELDVNLKPVKSYYLADEDTIRAAQAA
VAGQGKAKG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=250, Percent_Identity=54, Blast_Score=284, Evalue=5e-77,
Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=57.2, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=54.8, Blast_Score=263, Evalue=8e-71,
Organism=Homo sapiens, GI4502445, Length=252, Percent_Identity=50, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI40353764, Length=252, Percent_Identity=50, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=56.1728395061728, Blast_Score=175, Evalue=3e-44,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=65.4471544715447, Blast_Score=322, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6322697, Length=253, Percent_Identity=52.9644268774704, Blast_Score=254, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6324516, Length=286, Percent_Identity=34.2657342657343, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320183, Length=300, Percent_Identity=30.6666666666667, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646216, Length=251, Percent_Identity=53.3864541832669, Blast_Score=270, Evalue=6e-73,
Organism=Drosophila melanogaster, GI85725270, Length=251, Percent_Identity=54.1832669322709, Blast_Score=260, Evalue=7e-70,
Organism=Drosophila melanogaster, GI85725272, Length=251, Percent_Identity=54.1832669322709, Blast_Score=260, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24650981, Length=251, Percent_Identity=54.1832669322709, Blast_Score=260, Evalue=7e-70,
Organism=Drosophila melanogaster, GI28571817, Length=249, Percent_Identity=39.3574297188755, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI28571815, Length=249, Percent_Identity=39.3574297188755, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24648979, Length=249, Percent_Identity=39.3574297188755, Blast_Score=184, Evalue=6e-47,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_AZOSB (A1K9B9)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934311.1
- ProteinModelPortal:   A1K9B9
- SMR:   A1K9B9
- STRING:   A1K9B9
- GeneID:   4607629
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2808
- eggNOG:   COG0588
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- PhylomeDB:   A1K9B9
- ProtClustDB:   PRK14115
- BioCyc:   ASP62928:AZO2808-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 27905; Mature: 27905

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKIVLLRHGESTWNKENRFTGWTDVDLTELGVGEARAAGQLLKREGYSFDLAFTSVLKR
CEEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCEEEHHHHHHHHH
ANKTLNIVLEELDALWLPVEHSWRLNERHYGALQGLNKAETAAKFGDDQVLVWRRSYDIP
CCHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEEGDERLNYDDPRYGSLPRARFPRTECLADTVARVVPYWETVIVPQILSGRRILIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AHGNSLRALIKYLDGISDGDIVGLNIPTAQPLVYELDVNLKPVKSYYLADEDTIRAAQAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCEECHHEEECCCHHHHHHHHH
VAGQGKAKG
HCCCCCCCC
>Mature Secondary Structure
MYKIVLLRHGESTWNKENRFTGWTDVDLTELGVGEARAAGQLLKREGYSFDLAFTSVLKR
CEEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCEEEHHHHHHHHH
ANKTLNIVLEELDALWLPVEHSWRLNERHYGALQGLNKAETAAKFGDDQVLVWRRSYDIP
CCHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEEGDERLNYDDPRYGSLPRARFPRTECLADTVARVVPYWETVIVPQILSGRRILIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AHGNSLRALIKYLDGISDGDIVGLNIPTAQPLVYELDVNLKPVKSYYLADEDTIRAAQAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCEECHHEEECCCHHHHHHHHH
VAGQGKAKG
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA