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The map label for this gene is ribD [H]

Identifier: 119899093

GI number: 119899093

Start: 3086189

End: 3087280

Strand: Direct

Name: ribD [H]

Synonym: azo2803

Alternate gene names: 119899093

Gene position: 3086189-3087280 (Clockwise)

Preceding gene: 119899092

Following gene: 119899099

Centisome position: 70.52

GC content: 70.79

Gene sequence:

>1092_bases
ATGACCTTTTCGGCGGCTGATCACGCCGCCATGGCGCGCGCGCTCGCGCTCGCTGCCAACGGCCTCTGTACCACCACCCC
CAATCCGCGCGTCGGCTGCGTGCTGGTACGCGACGGTGAGATCGTCGGCGAAGGCTGGCACCAGCGTGCCGGCGAAGCCC
ATGCCGAGGTCCATGCCCTGCGCGCCGCCGGCGAGCGTGCGGCAGGCGCCACGGCCTACGTCACGCTCGAACCCTGCTCC
CACTTCGGCCGCACCCCGCCGTGCTGCGAGGCGCTGGTCGCAGCCGGCGTCCGCCGCGTCGTCGCGGCCATGGAAGACCC
CAACCCGCTGGTCGCCGGCAGCGGCCTCGCGCGACTGCGCGCAGCCGGCATCGACACCGCCCACGGCCTGCTCGAAAGCG
AGGCGCGCGAACTCAACATCGGCTTCATCTCGCGCATGACCCGCGGTCGTCCCTGGGTGCGGCTGAAAGCGGCGGCGACG
CTCGACGGCAAGACCGCACTCGCCAATGGGGTCAGCCAGTGGATTACCGGGGAAGCCGCGCGCAGCGACGGCCATCGCTG
GCGCGCGCGCGCCTGCGCGATCCTGACCGGGATCGGCACCGTGCGCGAAGACGATCCCCAACTCACGGTGCGCGGGGTTC
CGTGCGAACGCCAGCCGCTACGCGTCGTGGTGGATGCACGGCTCGAGATCGGGCGCGAAGCGCGCATCCTGCAGGGCGCG
CCCGTCCTCATTGCCACGGCCATCGAAGAAGGCGAGCGCGCGGCGGAACTGCGCGCCGCCGGCCACGAAGTGCTGTCGCT
CGCCAACGAGGCGGGCAAGGTTGCGCTGCCCGCGCTGCTGCAGGCGCTGGCAGCACGCGGCATCAACGAACTGCACGTCG
AGGCCGGCTTCAAACTCAACGGCTCGTTGCTGCGCGAAGGGTGCGTGGACGAACTGTTGCTGTATATGGCGCCGATGCTG
GTCGGGGACAGTGCGCAGGGCATGTTCAACCTGAGCGCACTGACTTCGCTGGATCAGGCCCTGCGGCTCGACATCCGGGA
TATGCGCCGGATCGGCGAAGACTTCCGCGTCCTGGCCCGCCTGCGCGCTTAG

Upstream 100 bases:

>100_bases
AACTTCGCCGACGTGGACGAATTCTCGGAACTCGTGCGCGAAGTACAGACACGGCCCAAGCGCGGCCGGCCTGCCAATCC
CCAGCCCTCCGGCCCTGAAC

Downstream 100 bases:

>100_bases
GCCGGCACCCCGGTCAGCGCTGCCCGCACATCGCGCAAGCGGCATCCTGCCCGAGCGACACGCTGCGCCACTCCATCGCC
AGGCCATCGAGCAGCAGCAA

Product: AMP deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTFSAADHAAMARALALAANGLCTTTPNPRVGCVLVRDGEIVGEGWHQRAGEAHAEVHALRAAGERAAGATAYVTLEPCS
HFGRTPPCCEALVAAGVRRVVAAMEDPNPLVAGSGLARLRAAGIDTAHGLLESEARELNIGFISRMTRGRPWVRLKAAAT
LDGKTALANGVSQWITGEAARSDGHRWRARACAILTGIGTVREDDPQLTVRGVPCERQPLRVVVDARLEIGREARILQGA
PVLIATAIEEGERAAELRAAGHEVLSLANEAGKVALPALLQALAARGINELHVEAGFKLNGSLLREGCVDELLLYMAPML
VGDSAQGMFNLSALTSLDQALRLDIRDMRRIGEDFRVLARLRA

Sequences:

>Translated_363_residues
MTFSAADHAAMARALALAANGLCTTTPNPRVGCVLVRDGEIVGEGWHQRAGEAHAEVHALRAAGERAAGATAYVTLEPCS
HFGRTPPCCEALVAAGVRRVVAAMEDPNPLVAGSGLARLRAAGIDTAHGLLESEARELNIGFISRMTRGRPWVRLKAAAT
LDGKTALANGVSQWITGEAARSDGHRWRARACAILTGIGTVREDDPQLTVRGVPCERQPLRVVVDARLEIGREARILQGA
PVLIATAIEEGERAAELRAAGHEVLSLANEAGKVALPALLQALAARGINELHVEAGFKLNGSLLREGCVDELLLYMAPML
VGDSAQGMFNLSALTSLDQALRLDIRDMRRIGEDFRVLARLRA
>Mature_362_residues
TFSAADHAAMARALALAANGLCTTTPNPRVGCVLVRDGEIVGEGWHQRAGEAHAEVHALRAAGERAAGATAYVTLEPCSH
FGRTPPCCEALVAAGVRRVVAAMEDPNPLVAGSGLARLRAAGIDTAHGLLESEARELNIGFISRMTRGRPWVRLKAAATL
DGKTALANGVSQWITGEAARSDGHRWRARACAILTGIGTVREDDPQLTVRGVPCERQPLRVVVDARLEIGREARILQGAP
VLIATAIEEGERAAELRAAGHEVLSLANEAGKVALPALLQALAARGINELHVEAGFKLNGSLLREGCVDELLLYMAPMLV
GDSAQGMFNLSALTSLDQALRLDIRDMRRIGEDFRVLARLRA

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=362, Percent_Identity=51.1049723756906, Blast_Score=342, Evalue=3e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38533; Mature: 38402

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSAADHAAMARALALAANGLCTTTPNPRVGCVLVRDGEIVGEGWHQRAGEAHAEVHAL
CCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECCCEECCCHHHHCCHHHHHHHHH
RAAGERAAGATAYVTLEPCSHFGRTPPCCEALVAAGVRRVVAAMEDPNPLVAGSGLARLR
HHCCCCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHH
AAGIDTAHGLLESEARELNIGFISRMTRGRPWVRLKAAATLDGKTALANGVSQWITGEAA
HHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCCHHH
RSDGHRWRARACAILTGIGTVREDDPQLTVRGVPCERQPLRVVVDARLEIGREARILQGA
HCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEECHHHCCCCHHEECCC
PVLIATAIEEGERAAELRAAGHEVLSLANEAGKVALPALLQALAARGINELHVEAGFKLN
CEEEEEEHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCEEC
GSLLREGCVDELLLYMAPMLVGDSAQGMFNLSALTSLDQALRLDIRDMRRIGEDFRVLAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRA
HCC
>Mature Secondary Structure 
TFSAADHAAMARALALAANGLCTTTPNPRVGCVLVRDGEIVGEGWHQRAGEAHAEVHAL
CCCCHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECCCEECCCHHHHCCHHHHHHHHH
RAAGERAAGATAYVTLEPCSHFGRTPPCCEALVAAGVRRVVAAMEDPNPLVAGSGLARLR
HHCCCCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHH
AAGIDTAHGLLESEARELNIGFISRMTRGRPWVRLKAAATLDGKTALANGVSQWITGEAA
HHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCCHHH
RSDGHRWRARACAILTGIGTVREDDPQLTVRGVPCERQPLRVVVDARLEIGREARILQGA
HCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEECHHHCCCCHHEECCC
PVLIATAIEEGERAAELRAAGHEVLSLANEAGKVALPALLQALAARGINELHVEAGFKLN
CEEEEEEHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCEEC
GSLLREGCVDELLLYMAPMLVGDSAQGMFNLSALTSLDQALRLDIRDMRRIGEDFRVLAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]