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The map label for this gene is pgm [H]

Identifier: 119899068

GI number: 119899068

Start: 3057734

End: 3059125

Strand: Direct

Name: pgm [H]

Synonym: azo2778

Alternate gene names: 119899068

Gene position: 3057734-3059125 (Clockwise)

Preceding gene: 119899067

Following gene: 119899069

Centisome position: 69.87

GC content: 67.96

Gene sequence:

>1392_bases
ATGACCCAGTCCAAGCCCTTTGTTCCCGCCCCTGAAATCTTCAAGGCCTACGACATCCGCGGCATCGTCGACAAGACGCT
GACGGTCGAGGCGGTGCGCGCCATCGGCCAGGCCCTCGGCTCCGAGGCCCGCGCCCGCGGCCAGAAGGCGATCGCGGTCG
GCCGCGACGGCCGCCTGTCCGGCCCGGCACTCGCCGGCGCACTGGCCGACGGCATCCGCGCCGCCGGCGTGGACGTGGTC
GACATCGGCTGCGTACCCACCCCGCTCACCTACTTCGCCGCCTACCACCTCGGCACCGACTCCTGCGTGTCGGTCACCGG
CAGCCACAACCCGCCGGACTACAACGGCCTCAAGATGGTGCTCGGCGGCCAGACGCTGTACGGCGAACAGATCCTCGACC
TGCGCCGCCGCCTGATCGAGGGCGACCTCACCGAGGGCGCCGGGGAGCTGCGCACGGCGGACGTCAACGCGGCCTATCTG
GAACGCGTCACCTCCGACGTCAAGCTCTCCCGCCCCATGAAGATCGTCATGGACTGCGGCAACGGCGTCGCCGGCGCAAT
CGCCCCGGCGCTGTTCAAGCAGCTCGGCTGCGAACTGGTGGAACTCTTCTGCGAGGTCGACGGCAACTTCCCCAACCACC
ATCCGGATCCGTCCAAGCCCGAAAACCTGGAAGACGTGGTGCGCGCGCTGAAGGAAACCGATGCCGAACTCGGGCTGGCC
TTCGACGGCGACGGCGATCGCCTGGGCGTGGTGACGAAGGACGGCGAGATCATCTTCCCCGACCGCCAGCTGATGCTGTT
CGCCGAGGACGTGCTCTCGCGCGTGCCCGGCGGCGAGATCATCTACGACGTCAAATGCACCCGTAACCTCGCGGGCTGGA
TCAAGCAGCGCGGCGGCAAGGCGACCATGTGGAACACCGGCCACGCACTGGTCAAGGCCAAGCTCAAGGAAACCGGCGCC
CCGCTCGCTGGCGAGATGAGCGGCCACATGTTCTTCAAGGAACGCTGGTACGGTTTCGACGACGGCCTCTACGCCGGCGC
CCGCCTGCTCGAGATCCTGTCGCGCTCGGGCGACGCCAACGCGGTGCTGAAGGGCCTGCCGGACGCGGTGAGCACGCCCG
AACTCAACATCAAGATGAACGAGGGCGAACCCTTCGAACTGGTCAAGCGCCTCAAGGAACAGGCTCAGTTCGACGGCGCG
GTCGAGCGCATCACGCTCGACGGCGTGCGCGTGGAATACGCCGACGGTTTCGGCCTGGCGCGGCCGTCCAACACCACGCC
GGTGGTGGTGCTGCGTTTCGAGGCCAATGACGCGGCCGCGCTCACGCGCATCCAGGACGCCTTCCGTACCGCCATCACTT
CGGTGTGGCCGGGGGTCAAGCTGCCCTTCTGA

Upstream 100 bases:

>100_bases
GACGCAACGGCAGCGGCCGGCTTGCAAACCCAAACATCTAGCAGCGCACTGACATACTATCCTTCCCCGCTACCCATCCT
GATCGCATCGGAAGCCCTCC

Downstream 100 bases:

>100_bases
CCACCCGCCTCCGCACGCGGAGACCATGTCAAGACCGGGGGTTCGTGCTAGCCTCGCACGGATCCCCTTTTCATTTGTTC
ACGCCCCTCCGGACGCATGC

Product: putative phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTQSKPFVPAPEIFKAYDIRGIVDKTLTVEAVRAIGQALGSEARARGQKAIAVGRDGRLSGPALAGALADGIRAAGVDVV
DIGCVPTPLTYFAAYHLGTDSCVSVTGSHNPPDYNGLKMVLGGQTLYGEQILDLRRRLIEGDLTEGAGELRTADVNAAYL
ERVTSDVKLSRPMKIVMDCGNGVAGAIAPALFKQLGCELVELFCEVDGNFPNHHPDPSKPENLEDVVRALKETDAELGLA
FDGDGDRLGVVTKDGEIIFPDRQLMLFAEDVLSRVPGGEIIYDVKCTRNLAGWIKQRGGKATMWNTGHALVKAKLKETGA
PLAGEMSGHMFFKERWYGFDDGLYAGARLLEILSRSGDANAVLKGLPDAVSTPELNIKMNEGEPFELVKRLKEQAQFDGA
VERITLDGVRVEYADGFGLARPSNTTPVVVLRFEANDAAALTRIQDAFRTAITSVWPGVKLPF

Sequences:

>Translated_463_residues
MTQSKPFVPAPEIFKAYDIRGIVDKTLTVEAVRAIGQALGSEARARGQKAIAVGRDGRLSGPALAGALADGIRAAGVDVV
DIGCVPTPLTYFAAYHLGTDSCVSVTGSHNPPDYNGLKMVLGGQTLYGEQILDLRRRLIEGDLTEGAGELRTADVNAAYL
ERVTSDVKLSRPMKIVMDCGNGVAGAIAPALFKQLGCELVELFCEVDGNFPNHHPDPSKPENLEDVVRALKETDAELGLA
FDGDGDRLGVVTKDGEIIFPDRQLMLFAEDVLSRVPGGEIIYDVKCTRNLAGWIKQRGGKATMWNTGHALVKAKLKETGA
PLAGEMSGHMFFKERWYGFDDGLYAGARLLEILSRSGDANAVLKGLPDAVSTPELNIKMNEGEPFELVKRLKEQAQFDGA
VERITLDGVRVEYADGFGLARPSNTTPVVVLRFEANDAAALTRIQDAFRTAITSVWPGVKLPF
>Mature_462_residues
TQSKPFVPAPEIFKAYDIRGIVDKTLTVEAVRAIGQALGSEARARGQKAIAVGRDGRLSGPALAGALADGIRAAGVDVVD
IGCVPTPLTYFAAYHLGTDSCVSVTGSHNPPDYNGLKMVLGGQTLYGEQILDLRRRLIEGDLTEGAGELRTADVNAAYLE
RVTSDVKLSRPMKIVMDCGNGVAGAIAPALFKQLGCELVELFCEVDGNFPNHHPDPSKPENLEDVVRALKETDAELGLAF
DGDGDRLGVVTKDGEIIFPDRQLMLFAEDVLSRVPGGEIIYDVKCTRNLAGWIKQRGGKATMWNTGHALVKAKLKETGAP
LAGEMSGHMFFKERWYGFDDGLYAGARLLEILSRSGDANAVLKGLPDAVSTPELNIKMNEGEPFELVKRLKEQAQFDGAV
ERITLDGVRVEYADGFGLARPSNTTPVVVLRFEANDAAALTRIQDAFRTAITSVWPGVKLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=439, Percent_Identity=35.5353075170843, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1789566, Length=461, Percent_Identity=28.4164859002169, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 49841; Mature: 49710

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSKPFVPAPEIFKAYDIRGIVDKTLTVEAVRAIGQALGSEARARGQKAIAVGRDGRLS
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEEEECCCCCCC
GPALAGALADGIRAAGVDVVDIGCVPTPLTYFAAYHLGTDSCVSVTGSHNPPDYNGLKMV
CHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEE
LGGQTLYGEQILDLRRRLIEGDLTEGAGELRTADVNAAYLERVTSDVKLSRPMKIVMDCG
ECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCEEEEEECC
NGVAGAIAPALFKQLGCELVELFCEVDGNFPNHHPDPSKPENLEDVVRALKETDAELGLA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHEEEE
FDGDGDRLGVVTKDGEIIFPDRQLMLFAEDVLSRVPGGEIIYDVKCTRNLAGWIKQRGGK
ECCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCC
ATMWNTGHALVKAKLKETGAPLAGEMSGHMFFKERWYGFDDGLYAGARLLEILSRSGDAN
EEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCCCHHHHHHHHHHHHHCCCCCH
AVLKGLPDAVSTPELNIKMNEGEPFELVKRLKEQAQFDGAVERITLDGVRVEYADGFGLA
HHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCC
RPSNTTPVVVLRFEANDAAALTRIQDAFRTAITSVWPGVKLPF
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TQSKPFVPAPEIFKAYDIRGIVDKTLTVEAVRAIGQALGSEARARGQKAIAVGRDGRLS
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEEEECCCCCCC
GPALAGALADGIRAAGVDVVDIGCVPTPLTYFAAYHLGTDSCVSVTGSHNPPDYNGLKMV
CHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEE
LGGQTLYGEQILDLRRRLIEGDLTEGAGELRTADVNAAYLERVTSDVKLSRPMKIVMDCG
ECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCEEEEEECC
NGVAGAIAPALFKQLGCELVELFCEVDGNFPNHHPDPSKPENLEDVVRALKETDAELGLA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHEEEE
FDGDGDRLGVVTKDGEIIFPDRQLMLFAEDVLSRVPGGEIIYDVKCTRNLAGWIKQRGGK
ECCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCC
ATMWNTGHALVKAKLKETGAPLAGEMSGHMFFKERWYGFDDGLYAGARLLEILSRSGDAN
EEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCCCHHHHHHHHHHHHHCCCCCH
AVLKGLPDAVSTPELNIKMNEGEPFELVKRLKEQAQFDGAVERITLDGVRVEYADGFGLA
HHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCC
RPSNTTPVVVLRFEANDAAALTRIQDAFRTAITSVWPGVKLPF
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]