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The map label for this gene is yfhK [H]

Identifier: 119899058

GI number: 119899058

Start: 3048521

End: 3049915

Strand: Direct

Name: yfhK [H]

Synonym: azo2768

Alternate gene names: 119899058

Gene position: 3048521-3049915 (Clockwise)

Preceding gene: 119899056

Following gene: 119899059

Centisome position: 69.66

GC content: 70.11

Gene sequence:

>1395_bases
ATGCGCCATCCCTCGTTCCGCTTCACCTTGCTGGCCGGTTTTCTGCTCGTCGCGGGCGTGCTCGGCGCCATCGCCGCGAG
CGCTTGGCTGGGCCTCGCCGACTTCGCTGCGCGCACCCGCGCGCAAGCAACCGAGGCCATCGCGATGTCGGCAGCGCTGC
AGCAACTGGGCGAGCGGACGATCGATCTGGAGCGCGCGCTGCGTCAATTCCTGGTGCTGCGCGATCCGGCCTTGCTGGAG
CGGATCCAGTCCGCGCGCGCGGAAGCCACCGCAGCGCTCGACCGCCTCGATGCCGCGCACCCGGTGTTGCGGGGCCTCAG
CGATGAGTGGCGGCGGCTCTCCGAACCCTCCGCCCTCGCCCCCGAAACCGTGCTTCCACACAGTGCCAGCGAGGCCGCCG
CCGCGCTGCAACGCCTGCGCGAAATCAACGCCACGCTCGCGCGCCGTCTCAACGATCTGCTCGAAAGCCAGAAGGCAACC
GAACTCGACGCGCTCGACCACCGCCGCGAGCAGCTGGCCGCCGAACTTGGCGCGGGTGTCGTGCTGGCGGCCCTGTTCGC
GCTGCTGATCGCATGGTGGATCCTGCGACCACTGCGCCAGCTCAGCCACGCGATCGCAGCCTTGGGCGAGGACCGCTTGG
CGGCACGGGTTGCGGTGGGCGGGCCGGCGGATCTGCGCGAACTGGGCACACGGCTGGACTGGTTGCGCCAACGCCTGGCC
GACCTCGAAGCCAACCGCAACCGCGTGCTGCGCCACGTTTCGCACGAGCTGAAGACGCCGCTCGCATCGCTGCGCGAAGG
CATCGCACTGCTCACCGACGGCGTGCCCGGCCCGCTCAACGCGGCCCAGCGCGAAGTCACCGGCATCCTCGCAGCCAATG
CCCGCAGCCTGCAGGAACGTATCGAACAGTTGCTCGACTACAACGCAAGCCAGTTCAATGCCGCCCAGCTCAACCGCCGC
CCGGTTTCGCTACGCGAGCTGGCCGCCGCGGTCCTCGACGAGCTGCGCCTGCCTGCCGAAAGCAAGGGGCTGAAGCTGTC
CCTCGAAGGCGAGGTGCCGGCGCTGGCTCTGGACGCGGACAAGATGCGCGTCGTGCTCTCCAACCTCATCACCAATGCGA
TTGCCGTCAGCCCTGCCGGCGGCGGGATCAGGCTGAGCCTGTCGCAGCAGCGCGACGGCGTCAGCCTCGACTGCACGGAC
GACGGGCCCGGCGTCGCGCCCGAGGATGCGGAGCGCATCTTCGAGCCCTTCGTGCGCGGACCGACCGCCGCGGGCAAGGG
CAGCGGCCTGGGCCTCGCCATCGCGCGTGAATTCGTCCGGGCCCATGGCGGCATCATCGGCTTGCGTCCGGCCTCGCGCG
GCGCGTGCTTTCACATCGAGCTGCCTTATGCCTGA

Upstream 100 bases:

>100_bases
GCGCATCCGGTTGCACTTCCTTACGTGGCGAGCGCCGCTGCGGCTCGTACACTCGGCTGTCCGTCGCATCCTCGCGGCCC
CCGTACCTCCCCACCCGCCG

Downstream 100 bases:

>100_bases
CCTGCGCCCCATCTGCCTCGCCCTCGTGCTCGCCCTTGCGCTGCAGGGCTGCGTTACCGCGCCGCCGGCCGAACCGCCAC
CACCACACCGCGCCGCCCCC

Product: putative two-component system sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MRHPSFRFTLLAGFLLVAGVLGAIAASAWLGLADFAARTRAQATEAIAMSAALQQLGERTIDLERALRQFLVLRDPALLE
RIQSARAEATAALDRLDAAHPVLRGLSDEWRRLSEPSALAPETVLPHSASEAAAALQRLREINATLARRLNDLLESQKAT
ELDALDHRREQLAAELGAGVVLAALFALLIAWWILRPLRQLSHAIAALGEDRLAARVAVGGPADLRELGTRLDWLRQRLA
DLEANRNRVLRHVSHELKTPLASLREGIALLTDGVPGPLNAAQREVTGILAANARSLQERIEQLLDYNASQFNAAQLNRR
PVSLRELAAAVLDELRLPAESKGLKLSLEGEVPALALDADKMRVVLSNLITNAIAVSPAGGGIRLSLSQQRDGVSLDCTD
DGPGVAPEDAERIFEPFVRGPTAAGKGSGLGLAIAREFVRAHGGIIGLRPASRGACFHIELPYA

Sequences:

>Translated_464_residues
MRHPSFRFTLLAGFLLVAGVLGAIAASAWLGLADFAARTRAQATEAIAMSAALQQLGERTIDLERALRQFLVLRDPALLE
RIQSARAEATAALDRLDAAHPVLRGLSDEWRRLSEPSALAPETVLPHSASEAAAALQRLREINATLARRLNDLLESQKAT
ELDALDHRREQLAAELGAGVVLAALFALLIAWWILRPLRQLSHAIAALGEDRLAARVAVGGPADLRELGTRLDWLRQRLA
DLEANRNRVLRHVSHELKTPLASLREGIALLTDGVPGPLNAAQREVTGILAANARSLQERIEQLLDYNASQFNAAQLNRR
PVSLRELAAAVLDELRLPAESKGLKLSLEGEVPALALDADKMRVVLSNLITNAIAVSPAGGGIRLSLSQQRDGVSLDCTD
DGPGVAPEDAERIFEPFVRGPTAAGKGSGLGLAIAREFVRAHGGIIGLRPASRGACFHIELPYA
>Mature_464_residues
MRHPSFRFTLLAGFLLVAGVLGAIAASAWLGLADFAARTRAQATEAIAMSAALQQLGERTIDLERALRQFLVLRDPALLE
RIQSARAEATAALDRLDAAHPVLRGLSDEWRRLSEPSALAPETVLPHSASEAAAALQRLREINATLARRLNDLLESQKAT
ELDALDHRREQLAAELGAGVVLAALFALLIAWWILRPLRQLSHAIAALGEDRLAARVAVGGPADLRELGTRLDWLRQRLA
DLEANRNRVLRHVSHELKTPLASLREGIALLTDGVPGPLNAAQREVTGILAANARSLQERIEQLLDYNASQFNAAQLNRR
PVSLRELAAAVLDELRLPAESKGLKLSLEGEVPALALDADKMRVVLSNLITNAIAVSPAGGGIRLSLSQQRDGVSLDCTD
DGPGVAPEDAERIFEPFVRGPTAAGKGSGLGLAIAREFVRAHGGIIGLRPASRGACFHIELPYA

Specific function: Probable member of a two-component regulatory system yfhA/yfhK. May activate yfhA by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082128, Length=412, Percent_Identity=33.7378640776699, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=30.5755395683453, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786783, Length=315, Percent_Identity=25.3968253968254, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1790346, Length=258, Percent_Identity=29.8449612403101, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=32.0175438596491, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787894, Length=295, Percent_Identity=27.7966101694915, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789808, Length=268, Percent_Identity=27.9850746268657, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=28.6384976525822, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=227, Percent_Identity=29.5154185022026, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=30.7017543859649, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789149, Length=260, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=28.2685512367491, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=26.8199233716475, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=220, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789403, Length=301, Percent_Identity=26.9102990033223, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788279, Length=288, Percent_Identity=24.6527777777778, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49837; Mature: 49837

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHPSFRFTLLAGFLLVAGVLGAIAASAWLGLADFAARTRAQATEAIAMSAALQQLGERT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDLERALRQFLVLRDPALLERIQSARAEATAALDRLDAAHPVLRGLSDEWRRLSEPSALA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
PETVLPHSASEAAAALQRLREINATLARRLNDLLESQKATELDALDHRREQLAAELGAGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VLAALFALLIAWWILRPLRQLSHAIAALGEDRLAARVAVGGPADLRELGTRLDWLRQRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHH
DLEANRNRVLRHVSHELKTPLASLREGIALLTDGVPGPLNAAQREVTGILAANARSLQER
HHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IEQLLDYNASQFNAAQLNRRPVSLRELAAAVLDELRLPAESKGLKLSLEGEVPALALDAD
HHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECHH
KMRVVLSNLITNAIAVSPAGGGIRLSLSQQRDGVSLDCTDDGPGVAPEDAERIFEPFVRG
HHHHHHHHHHHHHHEECCCCCCEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCC
PTAAGKGSGLGLAIAREFVRAHGGIIGLRPASRGACFHIELPYA
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCCC
>Mature Secondary Structure
MRHPSFRFTLLAGFLLVAGVLGAIAASAWLGLADFAARTRAQATEAIAMSAALQQLGERT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDLERALRQFLVLRDPALLERIQSARAEATAALDRLDAAHPVLRGLSDEWRRLSEPSALA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
PETVLPHSASEAAAALQRLREINATLARRLNDLLESQKATELDALDHRREQLAAELGAGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VLAALFALLIAWWILRPLRQLSHAIAALGEDRLAARVAVGGPADLRELGTRLDWLRQRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHH
DLEANRNRVLRHVSHELKTPLASLREGIALLTDGVPGPLNAAQREVTGILAANARSLQER
HHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IEQLLDYNASQFNAAQLNRRPVSLRELAAAVLDELRLPAESKGLKLSLEGEVPALALDAD
HHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECHH
KMRVVLSNLITNAIAVSPAGGGIRLSLSQQRDGVSLDCTDDGPGVAPEDAERIFEPFVRG
HHHHHHHHHHHHHHEECCCCCCEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCC
PTAAGKGSGLGLAIAREFVRAHGGIIGLRPASRGACFHIELPYA
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]