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The map label for this gene is ompR2 [H]

Identifier: 119899035

GI number: 119899035

Start: 3025977

End: 3026735

Strand: Direct

Name: ompR2 [H]

Synonym: azo2745

Alternate gene names: 119899035

Gene position: 3025977-3026735 (Clockwise)

Preceding gene: 119899033

Following gene: 119899036

Centisome position: 69.15

GC content: 68.77

Gene sequence:

>759_bases
ATGACCAACCAGCCAGATCACATCCTCATCGTCGATGACGATCGCGACATCCGCAGCCTGCTCGCCGATTACCTGGAGAA
GCAGGGCCTGCGCTGCACCACCGCGGCGGACGGCCGCGAGATGAAGGCGGCGCTGGAACGCCACCGTGTCGACCTGATCG
TGCTCGACCTGATGCTGCCGGGCGAAGACGGCCTGACGCTGTGCCGCAACCTGCGCGCCGGCGGCAGCCACGCCAACACG
CCGATCCTGATGCTGACCGCGCGCGGCGAGGACATGGACCGCATCATCGGTCTGGAGATGGGAGCCGACGACTACCTGCC
CAAGCCCTTCGTGCCGCGCGAACTCTATGCCCGCGTACGCGCCATCCTGCGCCGCGCGCGCGCGTTGCCCCCCAACCTCG
ACACCCAGCCGCAGGCGCAGGCGCGCGAGCTGCGCTTCGCGCAGTGGCGGCTCGACACCGTCAACCGCCACCTCATCGAT
GCGCAGGGCACCGTGGTGCCGTTGTCGGGCGCCGAATACCGCATGCTCGGCGTGTTCCTCGCCCATCCGCAGCGCGTGCT
GTCGCGCGATCAGTTGATGGAGCTGACCCAGGGCCGCGAAGCCGACGTGTTCGACCGCTCGATCGACCTGATGGTGAGCC
GCCTGCGCCAGCGCCTGGGGGATAACGCGCGCGAACCCGCCATCATCAAGACCGTGCGCAACGAGGGCTATGTGCTCAGC
GCCGAGGTCGTTGCCGGCGACGGGAGCCTGAGCCAGTGA

Upstream 100 bases:

>100_bases
GGCCGATTTGCATGGGCGTGTCAGCCGCGGCCGGTTTGATACGCTGGGATACATACCGGCGCCGCTGCCTCCCTAAGATG
CGGGCCATGGAGACCCACGC

Downstream 100 bases:

>100_bases
AGCTCCTGCCCCGGAGCCTGTTCGCGCGCCTGATGCTGATCTGGCTGGTCGGCATCGCCGCGGTGCTGACCGTGAGCGTG
CTGCTGTTCGTCGGCGAGCG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTNQPDHILIVDDDRDIRSLLADYLEKQGLRCTTAADGREMKAALERHRVDLIVLDLMLPGEDGLTLCRNLRAGGSHANT
PILMLTARGEDMDRIIGLEMGADDYLPKPFVPRELYARVRAILRRARALPPNLDTQPQAQARELRFAQWRLDTVNRHLID
AQGTVVPLSGAEYRMLGVFLAHPQRVLSRDQLMELTQGREADVFDRSIDLMVSRLRQRLGDNAREPAIIKTVRNEGYVLS
AEVVAGDGSLSQ

Sequences:

>Translated_252_residues
MTNQPDHILIVDDDRDIRSLLADYLEKQGLRCTTAADGREMKAALERHRVDLIVLDLMLPGEDGLTLCRNLRAGGSHANT
PILMLTARGEDMDRIIGLEMGADDYLPKPFVPRELYARVRAILRRARALPPNLDTQPQAQARELRFAQWRLDTVNRHLID
AQGTVVPLSGAEYRMLGVFLAHPQRVLSRDQLMELTQGREADVFDRSIDLMVSRLRQRLGDNAREPAIIKTVRNEGYVLS
AEVVAGDGSLSQ
>Mature_251_residues
TNQPDHILIVDDDRDIRSLLADYLEKQGLRCTTAADGREMKAALERHRVDLIVLDLMLPGEDGLTLCRNLRAGGSHANTP
ILMLTARGEDMDRIIGLEMGADDYLPKPFVPRELYARVRAILRRARALPPNLDTQPQAQARELRFAQWRLDTVNRHLIDA
QGTVVPLSGAEYRMLGVFLAHPQRVLSRDQLMELTQGREADVFDRSIDLMVSRLRQRLGDNAREPAIIKTVRNEGYVLSA
EVVAGDGSLSQ

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=45.4935622317597, Blast_Score=197, Evalue=4e-52,
Organism=Escherichia coli, GI1790863, Length=240, Percent_Identity=35.8333333333333, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=39.1489361702128, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1787229, Length=240, Percent_Identity=36.6666666666667, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=35.8974358974359, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=38.3333333333333, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI2367329, Length=238, Percent_Identity=38.655462184874, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=33.4745762711864, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=36.7521367521368, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=31.6239316239316, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=34.3347639484979, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786911, Length=237, Percent_Identity=34.1772151898734, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=32.4786324786325, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=37.9310344827586, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322000, Length=173, Percent_Identity=27.7456647398844, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28313; Mature: 28182

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQPDHILIVDDDRDIRSLLADYLEKQGLRCTTAADGREMKAALERHRVDLIVLDLMLP
CCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCEEEEEEEEEC
GEDGLTLCRNLRAGGSHANTPILMLTARGEDMDRIIGLEMGADDYLPKPFVPRELYARVR
CCCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHEEEECCCCCCCCCCCCCHHHHHHHH
AILRRARALPPNLDTQPQAQARELRFAQWRLDTVNRHLIDAQGTVVPLSGAEYRMLGVFL
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCEEEHHHHH
AHPQRVLSRDQLMELTQGREADVFDRSIDLMVSRLRQRLGDNAREPAIIKTVRNEGYVLS
HCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCEEEE
AEVVAGDGSLSQ
EEEEECCCCCCC
>Mature Secondary Structure 
TNQPDHILIVDDDRDIRSLLADYLEKQGLRCTTAADGREMKAALERHRVDLIVLDLMLP
CCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCEEEEEEEEEC
GEDGLTLCRNLRAGGSHANTPILMLTARGEDMDRIIGLEMGADDYLPKPFVPRELYARVR
CCCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHEEEECCCCCCCCCCCCCHHHHHHHH
AILRRARALPPNLDTQPQAQARELRFAQWRLDTVNRHLIDAQGTVVPLSGAEYRMLGVFL
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCEEEHHHHH
AHPQRVLSRDQLMELTQGREADVFDRSIDLMVSRLRQRLGDNAREPAIIKTVRNEGYVLS
HCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCEEEE
AEVVAGDGSLSQ
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]