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The map label for this gene is pepM [H]

Identifier: 119898988

GI number: 119898988

Start: 2975648

End: 2976952

Strand: Direct

Name: pepM [H]

Synonym: azo2698

Alternate gene names: 119898988

Gene position: 2975648-2976952 (Clockwise)

Preceding gene: 119898987

Following gene: 119898989

Centisome position: 68.0

GC content: 61.76

Gene sequence:

>1305_bases
ATGAAAACGAAGATCGTGTATGTCGGCATGAGCGCCGACCTCGTCCACTCAGGCCACCTGAACATCATCCGCCACGCTGC
AAGCCTGGGCGAAGTCGTGATCGGACTGCTGACCGACAAGGCCATTGCGAGTTACAAGCGCATTCCGTACATGCCCTTCG
AGCAAAGGATGGCGGTGGTCGAGAATATCAAGGGCGTCTCGCGCGTCGTGCCCCAGACCACGCTCGACTACACGCCGAAT
CTCGAATTGCTCAAACCCGACTACGTGGTGCACGGCGATGACTGGCGCGAGGGCGTCCAGCGCGAAACGCGGCAGAAAGT
CATCGACACGCTCAAGCAATGGGGCGGCGAACTGGTGGAGATTCCTTACACCGCCGGCATTTCATCCACCCGTCTGCAGG
CCGCGATCAAGGAAATCGGCACCACGCCCGACATCCGGCGCAGCGCCCTGCGCCGCCTGCTGCAGGTCAAGCCGCTGATC
CGCTTTCTCGATATCCATAACGCCCTCTCGGGGCTGATCATCGAGCACACCGCGGTGGATACGCCCAGCGGACGACGCGA
GTTCGACGGCATGTGGGGCAGCAGCCTGACCGACTCGACCGCAAAGGGAAAACCCGACATCGAGGCGGTCGACGTTTCCG
CCCGGGTGCAGACGCTCAACGAAGTCCTGGAAGTCACCACCAAGCCCATCATCTACGACGGCGATACCGGCGGTCAGCCC
GAACATTTCAACTTCACGGTCCGCACGCTGGAGCGCCTGGGCATCTCGGCGATCGTCATCGAGGACAAGACCGGGCTGAA
GCGCAATTCGCTGTTCGGCAACGACGTGCCGCAAACGCAGGAGAGCATCGAGAACTTCTGCAACAAGATCCGCACCGGCA
AGCGCGCGCAGGCGACCGACGAGTTCATGATCATCGCCCGCATCGAAAGCCTCATCCTGGACAAGGGCGTCGATGATGCG
ATCGAACGTGCGCAAGCCTATCTGGCCGCGGGCGCGGACGGCATCATGATCCACAGCCGCAAGACCACGCCCGACGAAAT
CTTCGCGTTCTGCGAGCGCTACCGCCAGCTCGAAAACCGCAAGTACCTGGTGGCGGTGCCGTCCACCTACAACACCGTCA
CCGAAGAAGAACTGCAGCAACGCGGCGTGAACATCGTCATCTACGCCAACCACCTGTTGCGCAGCGCGTACCCGGCCATG
GTCGAGACCGCCAGGTGCATCCTGGAGCATCACCGCTCCTCCGAGTGCGACGCCCGGCTGCTTCCGATCAACGATATATT
GGCACTCATTCCAGGCACCCGATGA

Upstream 100 bases:

>100_bases
GCCCGGGTGGTGGCCGAGAAACGAAACCCGCACCGTTTCTTCAACCACCTGCTGAAGCGCTCGTGCGCCACTCAATCAAA
CATCGGGAGCGAGAAACGAC

Downstream 100 bases:

>100_bases
TGATCGACCCCGGCCATTTCCTCGATTCCCTGCGCCGTCGCGGCGTCGACTTCTTTACCGGCGTTCCCGATTCGCTGCTG
GCGAGTTTCTGCGCCTATGT

Product: putative phosphoenolpyruvate phosphomutase

Products: NA

Alternate protein names: PPH [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKTKIVYVGMSADLVHSGHLNIIRHAASLGEVVIGLLTDKAIASYKRIPYMPFEQRMAVVENIKGVSRVVPQTTLDYTPN
LELLKPDYVVHGDDWREGVQRETRQKVIDTLKQWGGELVEIPYTAGISSTRLQAAIKEIGTTPDIRRSALRRLLQVKPLI
RFLDIHNALSGLIIEHTAVDTPSGRREFDGMWGSSLTDSTAKGKPDIEAVDVSARVQTLNEVLEVTTKPIIYDGDTGGQP
EHFNFTVRTLERLGISAIVIEDKTGLKRNSLFGNDVPQTQESIENFCNKIRTGKRAQATDEFMIIARIESLILDKGVDDA
IERAQAYLAAGADGIMIHSRKTTPDEIFAFCERYRQLENRKYLVAVPSTYNTVTEEELQQRGVNIVIYANHLLRSAYPAM
VETARCILEHHRSSECDARLLPINDILALIPGTR

Sequences:

>Translated_434_residues
MKTKIVYVGMSADLVHSGHLNIIRHAASLGEVVIGLLTDKAIASYKRIPYMPFEQRMAVVENIKGVSRVVPQTTLDYTPN
LELLKPDYVVHGDDWREGVQRETRQKVIDTLKQWGGELVEIPYTAGISSTRLQAAIKEIGTTPDIRRSALRRLLQVKPLI
RFLDIHNALSGLIIEHTAVDTPSGRREFDGMWGSSLTDSTAKGKPDIEAVDVSARVQTLNEVLEVTTKPIIYDGDTGGQP
EHFNFTVRTLERLGISAIVIEDKTGLKRNSLFGNDVPQTQESIENFCNKIRTGKRAQATDEFMIIARIESLILDKGVDDA
IERAQAYLAAGADGIMIHSRKTTPDEIFAFCERYRQLENRKYLVAVPSTYNTVTEEELQQRGVNIVIYANHLLRSAYPAM
VETARCILEHHRSSECDARLLPINDILALIPGTR
>Mature_434_residues
MKTKIVYVGMSADLVHSGHLNIIRHAASLGEVVIGLLTDKAIASYKRIPYMPFEQRMAVVENIKGVSRVVPQTTLDYTPN
LELLKPDYVVHGDDWREGVQRETRQKVIDTLKQWGGELVEIPYTAGISSTRLQAAIKEIGTTPDIRRSALRRLLQVKPLI
RFLDIHNALSGLIIEHTAVDTPSGRREFDGMWGSSLTDSTAKGKPDIEAVDVSARVQTLNEVLEVTTKPIIYDGDTGGQP
EHFNFTVRTLERLGISAIVIEDKTGLKRNSLFGNDVPQTQESIENFCNKIRTGKRAQATDEFMIIARIESLILDKGVDDA
IERAQAYLAAGADGIMIHSRKTTPDEIFAFCERYRQLENRKYLVAVPSTYNTVTEEELQQRGVNIVIYANHLLRSAYPAM
VETARCILEHHRSSECDARLLPINDILALIPGTR

Specific function: Hydrolyzes phosphonopyruvate. Not active towards phosphoenolpyruvate, glycerophosphate, phospho-L-serine or phosphoglycolic acid [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily. PEP mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786525, Length=203, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000918
- InterPro:   IPR012649
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =3.11.1.3 [H]

Molecular weight: Translated: 48543; Mature: 48543

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKIVYVGMSADLVHSGHLNIIRHAASLGEVVIGLLTDKAIASYKRIPYMPFEQRMAVV
CCCEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ENIKGVSRVVPQTTLDYTPNLELLKPDYVVHGDDWREGVQRETRQKVIDTLKQWGGELVE
HHHHHHHHHCCCCCCCCCCCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEE
IPYTAGISSTRLQAAIKEIGTTPDIRRSALRRLLQVKPLIRFLDIHNALSGLIIEHTAVD
ECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
TPSGRREFDGMWGSSLTDSTAKGKPDIEAVDVSARVQTLNEVLEVTTKPIIYDGDTGGQP
CCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEECCCCCCC
EHFNFTVRTLERLGISAIVIEDKTGLKRNSLFGNDVPQTQESIENFCNKIRTGKRAQATD
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCH
EFMIIARIESLILDKGVDDAIERAQAYLAAGADGIMIHSRKTTPDEIFAFCERYRQLENR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
KYLVAVPSTYNTVTEEELQQRGVNIVIYANHLLRSAYPAMVETARCILEHHRSSECDARL
EEEEECCCCCCCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LPINDILALIPGTR
ECHHHHHHHCCCCC
>Mature Secondary Structure
MKTKIVYVGMSADLVHSGHLNIIRHAASLGEVVIGLLTDKAIASYKRIPYMPFEQRMAVV
CCCEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ENIKGVSRVVPQTTLDYTPNLELLKPDYVVHGDDWREGVQRETRQKVIDTLKQWGGELVE
HHHHHHHHHCCCCCCCCCCCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEE
IPYTAGISSTRLQAAIKEIGTTPDIRRSALRRLLQVKPLIRFLDIHNALSGLIIEHTAVD
ECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
TPSGRREFDGMWGSSLTDSTAKGKPDIEAVDVSARVQTLNEVLEVTTKPIIYDGDTGGQP
CCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEECCCCCCC
EHFNFTVRTLERLGISAIVIEDKTGLKRNSLFGNDVPQTQESIENFCNKIRTGKRAQATD
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCH
EFMIIARIESLILDKGVDDAIERAQAYLAAGADGIMIHSRKTTPDEIFAFCERYRQLENR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
KYLVAVPSTYNTVTEEELQQRGVNIVIYANHLLRSAYPAMVETARCILEHHRSSECDARL
EEEEECCCCCCCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LPINDILALIPGTR
ECHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12697754 [H]